
High dose of commercial products of kava (Piper methysticum) markedly enhanced hepatic cytochrome P450 1A1 mRNA expression with liver enlargement in rats
Keywords: کبد چرب; CYP, cytochrome P450; CP, cyclophilin A; ER, ethoxyresorufin; EROD, ethoxyresorufin O-deethylase; RT-PCR, reverse transcription-polymerase chain reactionKava; Piper methysticum; Cytochrome P450 1A1; mRNA expression; Real-time RT-PCR; Rat liver; Hepatotoxi