
Regulation of SIRT1 in aging: Roles in mitochondrial function and biogenesis
Keywords: SIRT1, sirtuin 1; PGC-1α, peroxisome proliferator activated receptor γ co-activator 1α; HIF-1α, hypoxia-inducible factor 1α; ROS, reactive oxygen species; RC, respiratory chain; NAD, nicotinamide adenine dinucleotide; mtDNA, mitochondrial DNA; OXPHOS, oxi