Keywords: Vaccine; Genetically engineered; Virus; Replicon; Live-attenuated; Directive; Europe; Reverse genetics;
مقالات ISI (ترجمه نشده)
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: Bromocriptine; Dengue virus; Focus assay; Time-of-drug addition; Replicon; Antiviral drug; DENV; dengue virus; DF; dengue fever; DHF; dengue hemorrhagic fever; DSS; dengue shock syndrome; NS; non-structural; BRC; bromocriptine; HTS; high-throughput screen
Keywords: Respiratory syncytial virus; Replicon; Diversity-oriented synthesis;
Keywords: RSV; Replicon; HTS; Antiviral; Luminescence; Multiplex
Keywords: Dengue vaccine; Pseudoinfectious virus; Replicon; Packaging cell; Immunogenicity;
Keywords: Vaccine; Rift Valley fever virus; Comparative; Sheep; Nonspreading; Replicon; R566; Clone 13; NSR-Gn;
A helicase-containing module defines a family of pCD630-like plasmids in Clostridium difficile
Keywords: Plasmid; Replicon; Helicase; Replication;
Establishment of robust HCV genotype 4d, 5a, and 6a replicon systems
Keywords: Hepatitis C virus; Genotype; Subtype; Replicon; Direct acting antiviral;
A near full-length open reading frame next generation sequencing assay for genotyping and identification of resistance-associated variants in hepatitis C virus
Keywords: RAS; NGS; Genotyping; Subgenome; RT-PCR; Replicon;
Current status and future development of infectious cell-culture models for the major genotypes of hepatitis C virus: Essential tools in testing of antivirals and emerging vaccine strategies
Keywords: HCV; Hepatitis C virus; Cell culture; In vitro; Full-length HCV; Chimeric HCV; HCV treatment in vitro; HCV vaccine; Pseudo-particle; Replicon; HCVcc; Neutralizing antibodies; Direct acting antivirals; DAA;
Discovery of novel tricyclic indole derived inhibitors of HCV NS5B RNA dependent RNA polymerase
Keywords: HCV; NS5B; Tricyclic Indole; Pyridone; Replicon;
Insights into the coordinated interplay of the sHP hairpin and its co-existing and mutually-exclusive dengue virus terminal RNA elements for viral replication
Keywords: Dengue virus (DENV); Replicon; RNA elements; Viral genome circularization; Mutagenesis analysis; Suppressor screening;
Zika Virus Replicons for Drug Discovery
Keywords: Zika; Drug discovery; Replicon; Flavivirus;
Discovery of 2-(4-sulfonamidophenyl)-indole 3-carboxamides as potent and selective inhibitors with broad hepatitis C virus genotype activity targeting HCV NS4B
Keywords: CQDSXYOVMHALPF-UHFFFAOYSA-N; OBULGMCFXOTNNK-ZDUSSCGKSA-N; DUGHOSNYUCLBTI-UHFFFAOYSA-N; HCV inhibitor; Replicon; 2-(4-Sulfonamidophenyl)-indole 3-carboxamides; NS4B;
The N-terminus of classical swine fever virus (CSFV) nonstructural protein 2 modulates viral genome RNA replication
Keywords: Classical swine fever virus; Nonstructural protein 2; Replication; Replicon
Control of alphavirus-based gene expression using engineered riboswitches
Keywords: Alphavirus; Replicon; Riboswitch; Aptamer; Venezuelan equine encephalitis virus;
Advances in experimental systems to study hepatitis C virus in vitro and in vivo
Keywords: Hepatitis C virus; Model systems; Replicon; Pseudoparticles; Soluble E2; Cell culture-derived HCV; Hepatocye-based models; Animal models;
6-(Azaindol-2-yl)pyridine-3-sulfonamides as potent and selective inhibitors targeting hepatitis C virus NS4B
Keywords: SNKXAUJPUHFFKN-NSHDSACASA-N; ZLGQGMUTVCQNFC-NSHDSACASA-N; HCV inhibitors; Replicon; 6-(Azaindol-2-yl)pyridine-3-sulfonamides; Structure-activity relationship; NS4B;
A simple and efficient strategy for the de novo construction of greater-than-genome-length hepatitis B virus replicons
Keywords: Hepatitis B virus; Greater-than-genome-length; Replicon; Construction strategy; Q5 high-fidelity DNA polymerase;
FMDV replicons encoding green fluorescent protein are replication competent
Keywords: FMDV; Replicon; Fluorescence; Replication;
The flavonoid apigenin inhibits hepatitis C virus replication by decreasing mature microRNA122 levels
Keywords: HCV; MicroRNA; Replicon; Polyphenol;
Transient replication of a hepatitis C virus genotype 1b replicon chimera encoding NS5A-5B from genotype 3a
Keywords: Hepatitis C virus; Genotype 3; Replicon; NS5A; NS5B; chimera;
Suppression of hepatitis C virus replication by cyclin-dependent kinase inhibitors
Keywords: HCV; CDK inhibitor; Rb; Replicon; Chimera mice;
A cyclic peptide mimic of an RNA recognition motif of human La protein is a potent inhibitor of hepatitis C virus
Keywords: Cyclic peptide; HCV translation; Replicon; Beta-turn;
Discovery of N-(4â²-(indol-2-yl)phenyl)sulfonamides as novel inhibitors of HCV replication
Keywords: XWIQJWPECYLWPI-UHFFFAOYSA-N; WIPLOYWKZIZQLE-UHFFFAOYSA-N; VXAPAEVOOKHHDG-UHFFFAOYSA-N; HCV inhibitors; Replicon; N-(Indol-2-yl)phenyl sulfonamide; Structure-activity relationship;
Discovery of novel HCV inhibitors: Synthesis and biological activity of 6-(indol-2-yl)pyridine-3-sulfonamides targeting hepatitis C virus NS4B
Keywords: HCV inhibitors; Replicon; 6-(Indol-2-yl)pyridine-3-sulfonamides; NS4B;
A new system to measure and compare hepatitis C virus replication capacity using full-length, replication competent viruses
Keywords: Fitness; Drug resistance; Immune escape; Replicon; HCV;
Utility of the Sindbis replicon system as an Env-targeted HIV vaccine
Keywords: VEEV; Venezuelan equine encephalitis virus; SFV; Semliki forest virus; SIN; Sindbis virus; nsPs; non-structural proteins; PKR; dsRNA-dependent protein kinase R; 2â²5â²OAS; 2â²5â²-linked oligoadenylate synthetase; Env; HIV-1 envelope protein; SIV; simi
RNA: The new revolution in nucleic acid vaccines
Keywords: Replicon; Manufacturing; Safety; Stability; Human;
Salmonid alphavirus replicon is functional in fish, mammalian and insect cells and in vivo in shrimps (Litopenaeus vannamei)
Keywords: Salmonid alphavirus; Replicon; Sav; dsRNA;
Development of a DNA-launched replicon as a vaccine for porcine reproductive and respiratory syndrome virus
Keywords: PRRSV; Replicon; DNA vaccine; Study in pigs
Characterization of three cryptic plasmids from Lactobacillus plantarum G63 that was isolated from Chinese pickle
Keywords: Lactobacillus plantarum; Cryptic plasmid; Replicon; Rep; IS; Mobilization
BiologÃa molecular aplicada del virus de la hepatitis C
Keywords: Virus de la hepatitis C; Hepatitis crónica C; ProteÃnas virales; Replicón; Cultivo celular del VHC; Hepatitis C virus; Chronic hepatitis C; Viral proteins; Replicons; HCV cell culture;
Tegobuvir (GS-9190) potency against HCV chimeric replicons derived from consensus NS5B sequences from genotypes 2b, 3a, 4a, 5a, and 6a
Keywords: HCV; NS5B; GS-9190; Tegobuvir; Chimeric; Replicon
Efficacy of three candidate Rift Valley fever vaccines in sheep
Keywords: Vaccine; Rift Valley fever virus; Sheep; Vector vaccine; Subunit; Nonspreading; Replicon;
Two independent replicons can support replication of the anthrax toxin-encoding plasmid pXO1 of Bacillus anthracis
Keywords: Plasmid pXO1; Replication; Replicon; TargeTron mutagenesis;
Beet soil-borne mosaic virus RNA-4 encodes a 32 kDa protein involved in symptom expression and in virus transmission through Polymyxa betae
Keywords: Benyvirus; Polymyxa betae; Trans-replication; Replicon; Transmission
Characterization of cell lines stably transfected with rubella virus replicons
Keywords: Rubella virus; Replicon; Togavirus; Persistent infection; Apoptosis; Interferon
Two PDZ binding motifs within NS5 have roles in Tick-borne encephalitis virus replication
Keywords: Flaviviruses; Tick-borne encephalitis virus replication; PDZ domains; NS5; Replicon;
Replicon-based Japanese encephalitis virus vaccines elicit immune response in mice
Keywords: Japanese encephalitis virus; Replicon; Packaging cell line; Pseudo-infectious particles;
Immunogenicity of a DNA-launched replicon-based canine parvovirus DNA vaccine expressing VP2 antigen in dogs
Keywords: DNA vaccine; Replicon; Canine parvovirus; Immunization; Dog;
Molecular and phenotypic characterisation of Extended Spectrum β-lactamase CTX-M Escherichia coli from farm animals in Great Britain
Keywords: Antibiotic resistance; Poultry; Cattle; Virulence; Replicon
Infected dendritic cells are sufficient to mediate the adjuvant activity generated by Venezuelan equine encephalitis virus replicon particles
Keywords: Adjuvant; Dendritic cell; Replicon; Alphavirus;
High prevalence of CTX-M-15-producing Klebsiella pneumoniae isolates in Asian countries: diverse clones and clonal dissemination
Keywords: Klebsiella pneumoniae; Extended-spectrum β-lactamase; Replicon
Mutational analysis of three predicted 5′-proximal stem-loop structures in the genome of tick-borne encephalitis virus indicates different roles in RNA replication and translation
Keywords: Flavivirus; TBEV; RNA replication and translation; Replicon; 5′noncoding region
Mutations in HCV non-structural genes do not contribute to resistance to nitazoxanide in replicon-containing cells
Keywords: Nitazoxanide; Hepatitis C virus; Drug resistance; Replicon; Cell culture
Discovery of benzimidazole-diamide finger loop (Thumb Pocket I) allosteric inhibitors of HCV NS5B polymerase: Implementing parallel synthesis for rapid linker optimization
Keywords: Hepatitis C virus; HCV; NS5B polymerase; Inhibition; Allosteric inhibitors; Replicon; Replication
Utilizing liver-specific microRNA-122 to modulate replication of dengue virus replicon
Keywords: Dengue virus; Replicon; microRNA-122;
Characterisation of the CTX-M-15-encoding gene in Klebsiella pneumoniae strains from the Barcelona metropolitan area: plasmid diversity and chromosomal integration
Keywords: blaCTX-M-15; Replicon; Klebsiella pneumoniae
Enhanced potency of individual and bivalent DNA replicon vaccines or conventional DNA vaccines by formulation with aluminum phosphate
Keywords: Botulinum neurotoxin; DNA vaccine; Replicon; Bivalent vaccine; Aluminum phosphate