Keywords: Hypertrophic cardiomyopathy; Pro-arrhythmic mechanisms; Repolarization reserve; Inter-subject variability; In silico drug testing;
مقالات ISI (ترجمه نشده)
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: AP; Action potential; APD; AP duration; BS; Brugada syndrome; CaMKII; Ca-calmodulin kinase II; CPVT; Catecholaminergic polymorphic ventricular tachycardia; CV; Conduction velocity; DAD; Delayed afterdepolarization; EAD; Early afterdepolarization; ERS; Ear
Keywords: Cardiac fibrosis; Ventricular fibrillation; Repolarization reserve; Oxidative stress; Anti-fibrotic therapy
Keywords: Methadone; QT interval; Channelopathies; Repolarization reserve
New in vitro model for proarrhythmia safety screening: IKs inhibition potentiates the QTc prolonging effect of IKr inhibitors in isolated guinea pig hearts
Keywords: ECG; Guinea pig hearts; Langendorff perfusion; Methods; Proarrhythmia; Rate corrected QT interval; Repolarization reserve; Safety screening; Synergism; Torsades de pointes;
A dual potassium channel activator improves repolarization reserve and normalizes ventricular action potentials
Keywords: AP; action potential; APD; action potential duration; EAD; early afterdepolarization; HF; heart failure; Electrophysiology; Action potential repolarization; Cultured cells; NS3623; Repolarization reserve;
Rabbit models as tools for preclinical cardiac electrophysiological safety testing: Importance of repolarization reserve
Keywords: Pre-clinical safety testing; Cardiac arrhythmias; Repolarization reserve; IKs; Species differences; Rabbit;
Cardiac late Na+ current: Proarrhythmic effects, roles in long QT syndromes, and pathological relationship to CaMKII and oxidative stress
Keywords: AP; action potential; APD; action potential duration; ATX-II; anemone toxin II; [Ca2+]i; intracellular calcium concentration; CaMKII; Ca2+/calmodulin-dependent protein kinase II; DAD; delayed afterdepolarization; EAD; early afterdepolarization; ICa-L; L-t
Repolarization reserve, arrhythmia and new drug development
Keywords: Repolarization reserve; Ion channels; Arrhythmias; QT prolongation; Drug development strategy
Arrhythmia formation in subclinical (“silent”) long QT syndrome requires multiple insults: Quantitative mechanistic study using the KCNQ1 mutation Q357R as example
Keywords: Action potential; β-Adrenergic stimulation; Computational models; Electrophysiology; Isoproterenol; Long-QT syndrome; Repolarization reserve; Silent mutationAP, action potential; APD, action potential duration; CL, cycle length; EAD, early afterdepolariza
Fragmented QRS is associated with torsades de pointes in patients with acquired long QT syndrome
Keywords: Acquired long QT syndrome; Fragmented QRS; Predisposing factor; Repolarization reserve; Torsades de pointesAP, action potential; ECG, electrocardiogram; fQRS, fragmented QRS; LQTS, long QT syndrome; NPV, negative predictable value; PPV, positive predictab
Does small-conductance calcium-activated potassium channel contribute to cardiac repolarization?
Keywords: SK2; Action potential; Apamin; Repolarization reserve; Intracellular calcium;
IKr channel blockade to unmask occult congenital long QT syndrome
Keywords: Long QT syndrome; Potassium channel blockade; Repolarization reserve; T peak-to-end interval