Suitability of PER.C6® cells to generate epidemic and pandemic influenza vaccine strains by reverse genetics
Keywords: معکوس ژنتیک; Influenza; Reverse genetics; Vaccine
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Development of combined vaccines for rabies and immunocontraception
Keywords: معکوس ژنتیک; Rabies virus ERA; Rabies virus gene relocation; Gonadotropin-releasing hormone (GnRH); Reverse genetics; Contraception;
Histidine at position 1042 of the p150 region of a KRT live attenuated rubella vaccine strain is responsible for the temperature sensitivity
Keywords: معکوس ژنتیک; Rubella virus; KRT vaccine strain; Temperature sensitivity; Reverse genetics
Sequence analysis of the large (L) polymerase gene and trailer of the peste des petits ruminants virus vaccine strain Nigeria 75/1: Expression and use of the L protein in reverse genetics
Keywords: معکوس ژنتیک; Peste des petits ruminants; Morbillivirus; Paramyxovirus; L polymerase; Reverse genetics
Efficient production of Rift Valley fever virus-like particles: The antiviral protein MxA can inhibit primary transcription of bunyaviruses
Keywords: معکوس ژنتیک; Rift Valley fever virus; Bunyavirus; Phlebovirus; Reverse genetics; Minireplicon system; Virus-like particles; Primary transcription; Interferon; MxA protein; Antiviral mechanism
Porcine reproductive and respiratory syndrome virus as a vector: Immunogenicity of green fluorescent protein and porcine circovirus type 2 capsid expressed from dedicated subgenomic RNAs
Keywords: معکوس ژنتیک; PRRSV; Reverse genetics; Foreign gene expression vector; Vaccine vector; Nidovirus; Arterivirus
Development of a hamster kidney cell line expressing stably T7 RNA polymerase using retroviral gene transfer technology for efficient rescue of infectious foot-and-mouth disease virus
Keywords: معکوس ژنتیک; Foot-and-mouth disease virus; Reverse genetics; Stable BHK-21 cell line; T7 RNA polymerase
Towards construction of viral vectors based on avian coronavirus infectious bronchitis virus for gene delivery and vaccine development
Keywords: معکوس ژنتیک; Coronavirus; Avian coronavirus infectious bronchitis virus; Reverse genetics; Viral vector; Gene delivery
Report of the 5th meeting on the evaluation of pandemic influenza prototype vaccines in clinical trials
Keywords: معکوس ژنتیک; AEFI; adverse events following immunisation; AlPO4; aluminium phosphate; Al(OH)3; aluminium hydroxide; CHMP; Committee for Human Medicinal Products; ECBS; Expert Committee on Biological Standardisation; HAI; haemagglutination-inhibition; LAIV; live-attenu
ReviewReverse genetics technology for Rift Valley fever virus: Current and future applications for the development of therapeutics and vaccines
Keywords: معکوس ژنتیک; Vaccine; Rift Valley fever virus; Non-structural protein; Bunyavirus; Phlebovirus; Reverse genetics; cDNA clone; Infectious clone; Minigenome rescue; Virus-like particle; Attenuation;
Glycoprotein gene relocation in rabies virus
Keywords: معکوس ژنتیک; ERA rabies virus; Reverse genetics; Gene rearrangement; Nuclear location signal;
Virus-induced gene silencing in Medicago truncatula and Lathyrus odorata
Keywords: معکوس ژنتیک; Reverse genetics; Leguminosae
A spectroscopic assessment of cellulose and the molecular mechanisms of cellulose biosynthesis in the ascidian Ciona intestinalis
Keywords: معکوس ژنتیک; hpf, hours post fertilization; MFSW, Millipore-filtered seawater; MO, morpholino antisense oligonucleotide.Functional genomics; Fourier transform infrared spectroscopy; Reverse genetics; Horizontal gene transfer
Establishment of reverse genetics system of betanodavirus for the efficient recovery of infectious particles
Keywords: معکوس ژنتیک; Fish virus; Betanodavirus; Reverse genetics; Infectious cDNA
An improved reverse genetics system for generation of bovine viral diarrhea virus as a BAC cDNA
Keywords: معکوس ژنتیک; Bacterial artificial chromosome; Full length cDNA clone; Reverse genetics; BVDV
Contribution of the leader sequence to homologous viral interference among Sendai virus strains
Keywords: معکوس ژنتیک; Paramyxovirus; Sendai virus; Persistent infection; Homologous interference; Reverse genetics; Leader sequence
RNA polymerase I-mediated expression of viral RNA for the rescue of infectious virulent and avirulent Rift Valley fever viruses
Keywords: معکوس ژنتیک; Bunyavirus; Phlebovirus; Rift Valley fever virus; Nonstructural protein NSs; Expression of reporter protein; Reverse genetics; RNA polymerase I;
Amino acid substitutions in the structural or nonstructural proteins of a vaccine strain of equine arteritis virus are associated with its attenuation
Keywords: معکوس ژنتیک; Equine arteritis virus; Reverse genetics; Infectious clone; Structural and nonstructural proteins; Attenuation; Vaccine;
Identification of virulence determinants of porcine reproductive and respiratory syndrome virus through construction of chimeric clones
Keywords: معکوس ژنتیک; PRRSV; Reverse genetics; Infectious clone; Modified live vaccines; Virulence
Generation and evaluation of reassortant influenza vaccines made by reverse genetics for H9N2 avian influenza in Korea
Keywords: معکوس ژنتیک; Avian influenza virus; Reverse genetics; Vaccine
Anti-lipopolysaccharide factor in Litopenaeus vannamei (LvALF): A broad spectrum antimicrobial peptide essential for shrimp immunity against bacterial and fungal infection
Keywords: معکوس ژنتیک; Anti-lipopolysaccharide factor; Antimicrobial peptide; Shrimp; Reverse genetics
The potential of a protease activation mutant of a highly pathogenic avian influenza virus for a pandemic live vaccine
Keywords: معکوس ژنتیک; Highly pathogenic influenza; Influenza life vaccine; Reverse genetics
A live attenuated cold-adapted influenza A H7N3 virus vaccine provides protection against homologous and heterologous H7 viruses in mice and ferrets
Keywords: معکوس ژنتیک; Avian influenza H7 virus; Reverse genetics; Live attenuated H7N3 virus vaccine; Immunogenicity; Efficacy
Genetic disruption of KSHV major latent nuclear antigen LANA enhances viral lytic transcriptional program
Keywords: معکوس ژنتیک; KSHV; LANA; Viral latency; Lytic replication; Viral transcriptional program; Reverse genetics
Reverse genetics approaches to combat pathogenic arenaviruses
Keywords: معکوس ژنتیک; Arenaviruses; Lassa virus; Junin virus; Lymphocytic choriomeningitis virus; Reverse genetics; Antivirals
Attenuation of porcine reproductive and respiratory syndrome virus strain MN184 using chimeric construction with vaccine sequence
Keywords: معکوس ژنتیک; Porcine respiratory and reproductive syndrome virus (PRRSV); Reverse genetics; Infectious clone; Chimera; Attenuation; Vaccine
SARS coronavirus replicase proteins in pathogenesis
Keywords: معکوس ژنتیک; SARS coronavirus; SARS-CoV; Replication; Pathogenesis; Reverse genetics; Protein processing; Temperature-sensitive mutants; ts mutants
Reverse genetics for peste-des-petits-ruminants virus (PPRV): Promoter and protein specificities
Keywords: معکوس ژنتیک; Peste-des-petits-ruminants virus (PPRV); Minigenome; Reverse genetics; Homologous/heterologous rescue; Chimeric minigenomes; PPRV proteins
Rift Valley fever virus lacking NSm proteins retains high virulence in vivo and may provide a model of human delayed onset neurologic disease
Keywords: معکوس ژنتیک; Rift Valley fever virus; NSm protein; Viral virulence factors; Bunyaviridae; Phlebovirus; Pathogenesis; Recombinant virus; Molecular pathogenesis; Reverse genetics; Hemorrhagic fever; Acute hepatic disease; Delayed neurologic disease; Rat model
Involvement of nucleoprotein, phosphoprotein, and matrix protein genes of rabies virus in virulence for adult mice
Keywords: معکوس ژنتیک; Rabies virus; Pathogenicity; Nucleoprotein; Phosphoprotein; Matrix protein; Reverse genetics
Avian-virus-like receptor specificity of the hemagglutinin impedes influenza virus replication in cultures of human airway epithelium
Keywords: معکوس ژنتیک; Influenza; Pandemics; Host range; Reverse genetics; Sialic acid; Receptor specificity, Cell tropism; Replication efficiency, Human airway epithelial cultures
The threat of peste des petits ruminants: progress in vaccine development for disease control
Keywords: معکوس ژنتیک; Peste des petits ruminants (PPR); Morbillivirus; Marker vaccine; Reverse genetics; Poxvirus recombinant vaccines
Tackling the intractable – Approaching the genetics of Chlamydiales
Keywords: معکوس ژنتیک; Chlamydia; Chlamydophia; Reverse genetics; Transcriptome analysis; Proteomics; Autotransporter; Surface display
An improved method for infectious bursal disease virus rescue using RNA polymerase II system
Keywords: معکوس ژنتیک; Infectious bursal disease virus; Reverse genetics; RNA polymerase II
Localizing the reovirus packaging signals using an engineered m1 and s2 ssRNA
Keywords: معکوس ژنتیک; Reovirus; Reverse genetics; M1 gene
Derivation of a novel SARS-coronavirus replicon cell line and its application for anti-SARS drug screening
Keywords: معکوس ژنتیک; SARS; Coronavirus; SARS-CoV; Reverse genetics; Replicon; Drug screening;
Evaluation of Newcastle disease virus chimeras expressing the Hemagglutinin-Neuraminidase protein of velogenic strains in the context of a mesogenic recombinant virus backbone
Keywords: معکوس ژنتیک; Newcastle disease; Hemagglutinin-Neuraminidase; Reverse genetics; Avian paramyxovirus; Pathogenicity indexes; Emerging diseases
A second RGD motif in the 1D capsid protein of a SAT1 type foot-and-mouth disease virus field isolate is not essential for attachment to target cells
Keywords: معکوس ژنتیک; FMDV; RGD; Integrin; Cell binding; Reverse genetics;
Generation of the influenza B viruses with improved growth phenotype by substitution of specific amino acids of hemagglutinin
Keywords: معکوس ژنتیک; Influenza B virus; Growth characteristics; Antigenic properties; Reverse genetics
The use of monoreassortants and reverse genetics to map reovirus lysis of a ras-transformed cell line
Keywords: معکوس ژنتیک; Reovirus; Monoreassortants; Reverse genetics; S4; Sigma 3
Are all lyssavirus genes equal for phylogenetic analyses?
Keywords: معکوس ژنتیک; Lyssavirus; Reverse genetics; Phylogenetic analysis; Protein co-variation
Control of rabies: Epidemiology of rabies in Asia and development of new-generation vaccines for rabies
Keywords: معکوس ژنتیک; Rabies virus; Molecular epidemiology; Asia; N gene; Vaccine; Reverse genetics; M geneVirus de la rage; épidémiologie moléculaire; Asie, Gène N; Vaccin; génétique réverse; gène M
Rescue system for measles virus from cloned cDNA driven by vaccinia virus Lister vaccine strain
Keywords: معکوس ژنتیک; Measles virus; Reverse genetics; Vaccinia virus Lister strain; Apoptosis
Passage in Vero cells alters the characteristics of measles AIK-C vaccine strain
Keywords: معکوس ژنتیک; Measles virus; Temperature sensitivity; Measles vaccine; Vero cells; Plaque assay; Reverse genetics
Pbcrk-1, the Plasmodium berghei orthologue of P. falciparum cdc-2 related kinase-1 (Pfcrk-1), is essential for completion of the intraerythrocytic asexual cycle
Keywords: معکوس ژنتیک; Plasmodium; Phosphorylation; Protein kinase; Cell cycle; Signal transduction; Reverse genetics
Development of a novel Borna disease virus reverse genetics system using RNA polymerase II promoter and SV40 nuclear import signal
Keywords: معکوس ژنتیک; Borna disease virus; Negative-strand RNA virus; Reverse genetics; RNA polymerase II promoter; SV40 nuclear import signal
Genetic mapping of the cold-adapted phenotype of B/Ann Arbor/1/66, the master donor virus for live attenuated influenza vaccines (FluMist®)
Keywords: معکوس ژنتیک; FluMist®; Influenza B virus; B/Ann Arbor/1/66 strain; Cold-adaptation; Reverse genetics
The development and characterization of H5 influenza virus vaccines derived from a 2003 human isolate
Keywords: معکوس ژنتیک; Avian influenza virus; Vaccine; Pandemic; Reverse genetics
Pathogenic potential of North American H7N2 avian influenza virus: A mutagenesis study using reverse genetics
Keywords: معکوس ژنتیک; Avian influenza virus; H7N2 subtype; Pathogenicity; Reverse genetics
Generation of High-yield Vaccine Strain Wholly Derived from Avian Influenza Viruses by Reverse Genetics
Keywords: معکوس ژنتیک; avian influenza virus; reverse genetics; high yield strain; vaccine evaluation;