دانلود مقالات ISI درباره Rho-Kinase + ترجمه فارسی

به روز رسانی در مورد نقش ایریسین در تنظیم فعالیت های غدد درون ریز و متابولیکی

An update on the role of irisin in the regulation of endocrine and metabolic functions

Keywords: AMPK; adenosine monophosphate, activated protein kinase; ATP; adenosine triphosphate; BAT; brown adipose tissue; BMI; body mass index; CAD; coronary artery disease; CK; creatinine kinase; CVD; cardiovascular disease; DM; diabetes mellitus; FNDC5; fibronec

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2018 سفارش ترجمه

مکانیزم های انعقاد انقباض عضلات صاف عروق برجسته اهداف کلیدی در بیماری های عروقی

Evolving mechanisms of vascular smooth muscle contraction highlight key targets in vascular disease

Keywords: AGE; Advanced Glycation End products; ALDH2; aldehyde dehydrogenase 2; AngII; angiotensin II; BKCa; large conductance Ca2+-activated K+ channel; Ca2+; calcium; [Ca2+]c; cytosolic free Ca2+ concentration; CaD; caldesmon, CaM, calmodulin; cAMP; cyclic adeno

دانلود رایگان متن کامل مقاله ISI 103 صفحه سال انتشار : 2018 سفارش ترجمه

تجویز موضعی یک مهار کننده راک / خالص باعث افزایش بقای سلول گانگلیونی شبکیه و بازسازی آکسون پس از آسیب عصبی بینایی

Topical administration of a Rock/Net inhibitor promotes retinal ganglion cell survival and axon regeneration after optic nerve injury

Keywords: Glaucoma; Optic nerve; Regeneration; Rho-kinase; Rock; rho-associated protein kinases; Net; norepinephrine transporters; IOP; intraocular pressure; RGC; retinal ganglion cell; TM; trabecular meshwork; CNS; central nerve system; CTB; cholera toxin B;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

اثرات فازودیل بر فشار خون ریوی در عمل بالینی

Effects of fasudil on pulmonary hypertension in clinical practice

Keywords: Pulmonary hypertension; Pulmonary arterial hypertension; Rho-kinase; Fasudil; CHD; congenital heart diseases; CI; cardiac index; CO; cardiac output; CTD; connective tissue diseases; CTEPH; chronic thromboembolic pulmonary hypertension; ERA; endothelin rec

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

استفاده از کوکسی ساییمیدیل استر دی سکته کربوکسی فلوئورسین برای نظارت بر گلیکسیون پروتئین داخل سلولی

Using carboxyfluorescein diacetate succinimidyl ester to monitor intracellular protein glycation

Keywords: Cellular protein glycation; Carboxyfluorescein diacetate succinimidyl ester (CFDA–SE); Glyoxal; Rho-kinase; Actin; Gelsolin

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

فیبروز کیستیک: به سوی درمان های شخصی

Cystic fibrosis: Toward personalized therapies

Keywords: CFTR; cystic fibrosis transmembrane conductance regulator; rAAV; recombinant adeno-associated virus; NBD; nucleotide binding domain; MSD; membrane spanning domain; iPSC; induced pluripotent stem cells; CRC; conditionally reprogrammed cells; ROCK; Rho-kina

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

درمان طولانی مدت با فوودیل، فیبروز ریوی ناشی از بلومویسین و فشار خون ریوی را از طریق مهار اسمز معکوس

Long-term treatment with fasudil improves bleomycin-induced pulmonary fibrosis and pulmonary hypertension via inhibition of Smad2/3 phosphorylation

Keywords: RhoA; Rho-kinases; Bleomycin; Pulmonary hypertension; Pulmonary fibrosis; PH; pulmonary hypertension; PF; pulmonary fibrosis; ILD; interstitial lung disease; IPF; idiopathic pulmonary fibrosis; CTD; connective tissue disease; ROCK; Rho-kinase; BALF; bronc

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Altered ureteral contractility with ageing: Role of the rho-kinase pathway

Keywords: Ureter; Rho-kinase; Fasudil; Y-27632; Alpha-adrenoceptor; 5-HT;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2018 سفارش ترجمه

Rho-associated kinase inhibitor enhances the culture condition of isolated mouse salivary gland cells in vitro

Keywords: ROCK; Rho-kinase; hESC; human embryonic stem cell; ROCK inhibitor; Y-27632; Hyposalivation; Submandibular salivary gland; Ductal cells; Primary cell culture;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2018 سفارش ترجمه

Role of rho-kinase (ROCK) in tonic but not phasic contraction in the frog stomach smooth muscle

Keywords: Rho-kinase; Contraction; Stomach; Smooth muscle; Frog;

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2018 سفارش ترجمه

Inhibition of Rho kinase by GSK 269962 reverses both corticosterone-induced detrusor overactivity and depression-like behaviour in rats

Keywords: Detrusor overactivity; Depression; GSK 269962; Rho-kinase; Pro-inflammatory cytokines; Rats;

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2018 سفارش ترجمه

Effects of chronic Δ9-tetrahydrocannabinol treatment on Rho/Rho-kinase signalization pathway in mouse brain

Keywords: Brain; Mice; RhoA; Rho-kinase; Δ9-Tetrahydrocannabinol;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2017 سفارش ترجمه

Original articleThe role of arachidonic acid/cyclooxygenase cascade, phosphodiesterase IV and Rho-kinase in H2S-induced relaxation in the mouse corpus cavernosum

Keywords: Arachidonic acid pathway; Corpus cavernosum; Hydrogen sulfide; Phosphodiesterase IV; Rho-kinase;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Functional involvement of protein kinase C, Rho-kinase and TRPC3 decreases while PLC increases with advancement of pregnancy in mediating oxytocin-induced myometrial contractions in water buffaloes (Bubalus bubalis)

Keywords: Oxytocin; Buffalo myometrium; Rho-kinase; PKC; Phospholipase-C; Store-operated Ca2+ channel/transient receptor potential channel;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

ROS-dependent activation of RhoA/Rho-kinase in pulmonary artery: Role of Src-family kinases and ARHGEF1

Keywords: Vascular smooth muscle; Tyrosine kinases; Src-family kinases; Reactive oxygen species; Hypoxia; Rho-kinase; Guanine nucleotide exchange factors; Pulmonary artery;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2017 سفارش ترجمه

Blood-brain barrier dysfunction induced by silica NPs in vitro and in vivo: Involvement of oxidative stress and Rho-kinase/JNK signaling pathways

Keywords: Silica nanoparticles; Blood-brain barrier; Tight junction; Inflammation; Oxidative stress; Rho-kinase;

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2017 سفارش ترجمه

Enhanced Rho-kinase activity: Pathophysiological relevance in type 2 diabetes

Keywords: Correlation; Rho-kinase; Type 2 diabetes;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

Survival of corticostriatal neurons by Rho/Rho-kinase signaling pathway

Keywords: NeuRet vector; neuron-specific retrograde gene transfer lentiviral vector; AAV vector; adeno-associated virus vector; C3 transferase; Clostridium botulinum C3 ADP-ribosyltransferase; Rho-K DN; dominant-negative form for Rho-kinase; Rho GTPase; Rho-kinase;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Impaired vascular function in sepsis-surviving rats mediated by oxidative stress and Rho-Kinase pathway

Keywords: AII; angiotensin II; AT1R; angiotensin II type 1 receptor; CAT; catalase; CLP; cecal ligation and puncture; CT; control; DHE; dihydroethidium; GSH; reduced glutathione; GST; glutathione S-transferase; LOOH; lipid hydroperoxide; MYPT-1; subunit 1 of the my

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Methylmercury affects cerebrovascular reactivity to angiotensin II and acetylcholine via Rho-kinase and nitric oxide pathways in mice

Keywords: Cerebral artery; Acetylcholine; Angiotensin II; Rho-kinase; Methylmercury

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Beneficial Effects of a Novel Bioabsorbable Polymer Coating on Enhanced Coronary Vasoconstricting Responses After Drug-Eluting Stent Implantation in Pigs in Vivo

Keywords: inflammation; polymers; stents; Rho-kinase; DES; drug-eluting stent(s); EES; everolimus-eluting stent(s); PCI; percutaneous coronary intervention; PDLLA-PCL; poly-dl-lactic acid and polycaprolactone; PLA; polylactic acid; P1+D+ stent; stent with a polylac

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Fasudil evokes vasodilatation of rat mesenteric vascular bed via Ca2+ channels and Rho/ROCK pathway

Keywords: Fasudil; Rho-kinase; Mesenteric artery; Endothelium; Calcium blocker; Nitric oxide;

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2016 سفارش ترجمه

Effects of 17β-estradiol and progesterone on the production of adipokines in differentiating 3T3-L1 adipocytes: Role of Rho-kinase

Keywords: Adipocyte; Adipokines; 17β-estradiol; Progesterone; Rho-kinase

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Rho-kinase signaling controls nucleocytoplasmic shuttling of class IIa Histone Deacetylase (HDAC7) and transcriptional activation of orphan nuclear receptor NR4A1

Keywords: ROCK; Rho kinase; OPHN1; Oligophrenin-1; HDAC7; Histone Deacetylase 7; MYPT1; myosin phosphatase subunit 1; MLCP; myosin light chain phosphatase; MLCK; myosin light chain kinase; NR4A1; nuclear receptor subfamily 4, group A, member 1; iPSCs; induced pluri

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Increased Rho-kinase-mediated prostate contractions associated with impairment of β-adrenergic-cAMP-signaling pathway by chronic nitric oxide deficiency

Keywords: Prostate; Nitric oxide; Rho-kinase; Beta-adrenergic pathway; L-NAME;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Cardiovascular pharmacologyEpidermal growth factor induces Ca2+ sensitization through Rho-kinase-dependent phosphorylation of myosin phosphatase target subunit 1 in vascular smooth muscle

Keywords: Smooth muscle; Epidermal growth factor; Myosin light chain phosphatase; Rho-kinase; Vasoconstriction; Myosin phosphatase target subunit 1;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Infralimbic cortex Rho-kinase inhibition causes antidepressant-like activity in rats

Keywords: IL, Infralimbic cortex; ROCK, Rho-kinase; fmi, forceps minor of the corpus callosumBehavior; Depression; Infralimbic cortex; Rho-kinase; Y-27632

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Protective effect of a novel Rho kinase inhibitor WAR–5 in experimental autoimmune encephalomyelitis by modulating inflammatory response and neurotrophic factors

Keywords: Experimental autoimmune encephalomyelitis; Rho-kinase; Y-27632 derivatives; NF–κB signaling

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Inhibition of the mevalonate pathway ameliorates anoxia-induced down-regulation of FKBP12.6 and intracellular calcium handling dysfunction in H9c2 cells

Keywords: DMEM; Dulbecco's modified Eagle's medium; DMSO; dimethylsulfoxide; FKBP; FK506-binding protein; FPP; farnesyl pyrophosphate; GAPDH; glyceraldehyde phosphate dehydrogenase; GGPP; geranylgeranyl pyrophosphate; HMG-CoA; 3-hydroxy-3-methylglutaryl-coenzyme A;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Antitumoral effect of a selective Rho-kinase inhibitor Y-27632 against Ehrlich ascites carcinoma in mice

Keywords: Rho-kinase; Y-27632; Ehrlich ascites carcinoma; Experimental tumor;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Rho-kinase limits BMP-4-stimulated osteocalcin synthesis in osteoblasts: Regulation of the p38 MAP kinase pathway

Keywords: Rho-kinase; BMP-4; Osteocalcin; MAP kinase; Osteoblast;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Bilateral crosstalk of rho- and extracellular-signal-regulated-kinase (ERK) pathways is confined to an unidirectional mode in spinal muscular atrophy (SMA)

Keywords: (ROCK); Rho-kinase; (ERK); extracellular signal regulated kinase; (SMA); Spinal Muscular Atrophy; Survival of motoneuron protein; Nuclear protein; Neurite outgrowth;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Long-term inhibition of Rho-kinase restores the LTP impaired in chronic forebrain ischemia rats by regulating GABAA and GABAB receptors

Keywords: ANOVA; analysis of variance; BCAO; bilateral common carotid artery occlusion; fEPSP; field excitatory postsynaptic potentiation; LTD; long-term depression; LTP; long-term potentiation; NMDA; N-methyl-d-aspartate; RT-PCR; real-time polymerase chain reactio

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Cell permeable peptide conjugated nanoerythrosomes of fasudil prolong pulmonary arterial vasodilation in PAH rats

Keywords: Targeted delivery; Rho-kinase; Fasudil; Nanoerythrosomes; Controlled release; Pulmonary arterial hypertension; Pulmonary delivery; SafetyALP, alkaline phosphatase; BAL, bronchoalveolar lavage; CAR, CARSKNKDC; 5-HT, 5-hydroxytryptamine; LDH, lactate dehydr

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

t-PA, but not desmoteplase, induces plasmin-dependent opening of a blood-brain barrier model under normoxic and ischaemic conditions

Keywords: BBB; blood-brain barrier; CNBr-fgn; cyanogen bromide-digested fibrinogen; FITC; fluorescein isothiocyanate; ICH; intracerebral haemorrhage; OGD; oxygen-glucose deprivation; LDLR; low density lipoprotein receptor; LRP-1; LDLR-related protein 1; PFA; parafo

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Effects of Rho-kinase inhibition in lung tissue with chronic inflammation

Keywords: Y-27632; Rho-kinase; Inflammation; Distal lung; Asthma

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Unfractionated heparin attenuates lung vascular leak in a mouse model of sepsis:Role of RhoA/Rho kinase pathway

Keywords: ALI; Acute lung injury; ROCK; Rho-kinase; LPS; Lipopolysaccharide; UFH; Unfractionated heparin; RT-PCR; Reverse Transcribed-Polymerase Chain Reaction; MYPT1; Myosin phosphatase target subunit 1; MLC; Myosin light-chain; unfractionated heparin; sepsis; acu

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Rho-kinase negatively regulates thyroid hormone-stimulated osteocalcin synthesis in osteoblasts

Keywords: Thyroid hormone; Rho-kinase; Osteocalcin; Osteoblast;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Pulmonary, gastrointestinal and urogenital pharmacologySignaling cross-talk between cannabinoid and muscarinic systems actives Rho-kinase and increases the contractile responses of the bovine ciliary muscle

Keywords: Cannabinoid; Muscarinic system; Ciliary muscle; Rho-kinase; Protein kinase C;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Aurora A kinase negatively regulates Rho-kinase by phosphorylation in vivo

Keywords: AurA; Aurora-A kinase; Drok; Drosophila Rho-kinase; Sqh; spaghetti squash (Myosin II regulatory light chain); Zip; zipper (Myosin II); Aurora-A kinase; Rho-kinase; Spaghetti squash; Myosin; Actin; Drosophila;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Effects of exercise training and RhoA/ROCK inhibition on plaque in ApoE−/− mice

Keywords: Exercise; Rho-kinase; Fasudil; Atherosclerosis; Plaque;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

H1152 promotes the degradation of polyglutamine-expanded ataxin-3 or ataxin-7 independently of its ROCK-inhibiting effect and ameliorates mutant ataxin-3-induced neurodegeneration in the SCA3 transgenic mouse

Keywords: Polyglutamine-expanded ataxin-3; Polyglutamine-expanded ataxin-7; H1152; Rho-kinase inhibitor; SCA3 transgenic mice; Pontine nuclei; SCA3; Spinocerebellar ataxia type 3; ROCK; Rho-kinase; SCA7; Spinocerebellar ataxia type 7;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Fasudil inhibits ER stress-induced VCAM-1 expression by modulating unfolded protein response in endothelial cells

Keywords: ER stress; Rho-kinase; Fasudil; Atherosclerosis

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Passive stiffness of airway smooth muscle: The next target for improving airway distensibility and treatment for asthma?

Keywords: Regulatable airway stiffness; Calcium-sensitive resistance to stretch; Rho-kinase;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

The role of Rho-kinases in ameloblast differentiation

Keywords: Rho-kinase; Rho-GTPase; Ameloblast; E-cadherin; Cytoskeleton

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Metabolic actions of Rho-kinase in periphery and brain

Keywords: Rho-kinase; glucose metabolism; insulin action; energy homeostasis; leptin action

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Therapeutic impact of eicosapentaenoic acid on ischemic brain damage following transient focal cerebral ischemia in rats

Keywords: Eicosapentaenoic acid; Oxidative stress; Rho-kinase; Focal cerebral ischemia

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Increased leukocyte Rho-associated coiled-coil containing protein kinase activity predicts the presence and severity of coronary vasospastic angina

Keywords: Angina; Calcium antagonist; Coronary vasospasm; Rho-kinase;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Inhibition of Rho-kinase ameliorates myocardial remodeling and fibrosis in pressure overload and myocardial infarction: Role of TGF-β1–TAK1

Keywords: Rho-kinase; TAC; MI; Myocardial fibrosis; TGF-β1–TAK1

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Research ArticleRho inhibitor prevents ischemia-reperfusion injury in rat steatotic liver

Keywords: IR; ischemia-reperfusion; SL; steatotic liver; HSCs; hepatic stellate cells; ROCK; Rho-kinase; MLC; myosin light chain; P-MLC; phosphorylated myosin light chain; NL; normal liver; fasudil; fasudil hydrochloride hydrate; NO; nitric oxide; l-NAME; N-nitro

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه