
Resistance to Selumetinib (AZD6244) in Colorectal Cancer Cell Lines is Mediated by p70S6K and RPS6 Activation 1
Keywords: MEK, mitogen-activated protein kinase; ERK, extracellular signal-regulated kinase; p70S6K, p70 S6 kinase; RPS6, ribosomal protein S6; RSK, p90 ribosomal S6 kinase; CRC, colorectal cancer