Keywords: RT، رونویسی معکوس; TERT, Telomerase reverse transcriptase; hTERT, Human telomerase reverse transcriptase; RT, Reverse transcriptase; TR, Telomerase RNA; hTR, Human telomerase RNA; RNP, Ribonucleoprotein; TEN, Essential N-terminal domain; TRBD, Telomerase RNA binding domain;
مقالات ISI RT، رونویسی معکوس (ترجمه نشده)
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Keywords: RT، رونویسی معکوس; FRT, female reproductive tract; LCM, laser capture micro-dissection; PRR, pattern recognition receptors; STIs, sexually transmitted infections; TLR, toll-like receptor; TBO, toluidine blue O; OCT, optimal cutting temperature; RT, reverse transcriptase; TA
Resolution of Specific Nucleotide Mismatches by Wild-Type and AZT-Resistant Reverse Transcriptases during HIV-1 Replication
Keywords: RT، رونویسی معکوس; RT, reverse transcriptase; WT, wild-type; AZTR, AZT-resistant; RIO, retroviral inside-out; LTR, long terminal repeat; ppt, polypurine tract; RSV, Rous sarcoma virus; PBS, primer binding site; RRE, Rev response elementretroviral error mechanisms; forced co
Discovery of non-peptide small molecular CXCR4 antagonists as anti-HIV agents: Recent advances and future opportunities
Keywords: RT، رونویسی معکوس; AIDS; HIV-1; CXCR4; Small molecular; Entry inhibitors; Drug designHIV-1, human immunodeficiency virus-1; AIDS, acquired immunodeficiency syndrome; WHO, world health organization; HAART, highly active antiretroviral therapy; RT, reverse transcriptase; NNRT
Systematic evaluation of methyl ester bioisosteres in the context of developing alkenyldiarylmethanes (ADAMs) as non-nucleoside reverse transcriptase inhibitors (NNRTIs) for anti-HIV-1 chemotherapy
Keywords: RT، رونویسی معکوس; ADAM, alkenyldiarylmethane; NNRTI, non-nucleoside reverse transcriptase inhibitor; RT, reverse transcriptase; HIV-1, human immunodeficiency virus type 1; AIDS, acquired immune deficiency syndrome; ART, antiretroviral therapy; NRTI, nucleoside reverse tran
Response to potent anti-HBV agents in chronic hepatitis B and combined effect of HBV reverse transcriptase mutations
Keywords: RT، رونویسی معکوس; HBV, hepatitis B virus; NA, nucleos(t)ide analogues; CHB, chronic hepatitis B; RT, reverse transcriptase; CVR, complete virological response; ETV, entecavir; TDF, tenofovir; RMSD, root mean square deviationHepatitis B virus; Nucleos(t)ide analogues; Rever
E138A in HIV-1 reverse transcriptase is more common in subtype C than B: Implications for rilpivirine use in resource-limited settings
Keywords: RT، رونویسی معکوس; RT, reverse transcriptase; NNRTI, nonnucleoside reverse transcriptase inhibitor; RPV, rilpivirine; ETR, etravirine; EV, efavirenz; NVP, nevirapine; PrEP, pre-exposure prophylaxisHIV-1; Reverse transcriptase; NNRTI; Rilpivirine; E138A; Resistance
Molecular mechanism of HIV-1 resistance to 3′-azido-2′,3′-dideoxyguanosine
Keywords: RT، رونویسی معکوس; RT, reverse transcriptase; RNase H, ribonuclease H; WT, wild-type; NRTI, nucleoside RT inhibitor; TP, triphosphate; DP, diphosphate; MP, monophosphate; T/P, template/primer; NRTIs, nucleoside reverse transcriptase inhibitors; 3′-Azido-ddG, 3′-azido-2′,3′-
Amino acid substitutions away from the RNase H catalytic site increase the thermal stability of Moloney murine leukemia virus reverse transcriptase through RNase H inactivation
Keywords: RT، رونویسی معکوس; HIV-1, human immunodeficiency virus type 1; MMLV, Moloney murine leukemia virus; RNase H, ribonuclease H; RT, reverse transcriptase; PAGE, polyacrylamide gel electrophoresisMoloney murine leukemia virus; Reverse transcriptase; RNase H activity; Template–p
Characterization and chromosomal organization of Ty1-copia retrotransposons in wax gourd
Keywords: RT، رونویسی معکوس; dN, non-synonymous substitution; dS, synonymous substitution; FISH, fluorescent in situ hybridization; LTR, long terminal repeat; PCR, polymerase chain reaction; RT, reverse transcriptase; TE, transposable elementWax gourd; Ty1-copia retrotransposons; Rev
A mechanistic and structural investigation of modified derivatives of the diaryltriazine class of NNRTIs targeting HIV-1 reverse transcriptase
Keywords: RT، رونویسی معکوس; HIV-1, human immunodeficiency virus type 1; RT, reverse transcriptase; NNRTI, non-nucleoside reverse transcriptase inhibitor; DAPY, diarylpyrimidine; DATA, diaryltriazine; NNIBP, non-nucleoside inhibitor binding pocket; PDB, protein data bankHIV-1; Revers
Specific features of HIV-1 integrase inhibition by bisphosphonate derivatives
Keywords: RT، رونویسی معکوس; HIV; Integrase; Bisphosphonates; Inhibitors; SARHAART, highly active antiretroviral therapy; IN, integrase; BP, bisphosphonate; INSTI, integrase strand transfer inhibitor; LEDGF, lens epithelium derived growth factor; RT, reverse transcriptase; VDPA, viny
Evolution of the ONSEN retrotransposon family activated upon heat stress in Brassicaceae
Keywords: RT، رونویسی معکوس; LTR, long terminal repeat; ABRC, Arabidopsis biological resource center; BLAST, basic local alignment search tool; TAIR, the Arabidopsis information resource; RT, reverse transcriptase; CDS, coding DNA sequence; TE, transposable elementRetrotransposon; Br
A M-MLV reverse transcriptase with reduced RNaseH activity allows greater sensitivity of gene expression detection in formalin fixed and paraffin embedded prostate cancer samples
Keywords: RT، رونویسی معکوس; CDH1, E-Cadherin; CDH2, N-Cadherin; FFPE, Formalin fixed paraffin embedded; MMLV, Moloney Murine Leukemia Virus; qRT-PCR, quantitative real-time PCR; RT, reverse transcriptase; RT-PCR, reverse transcriptase PCRFFPE; Reverse transcriptase; M-MLV; PCR
Constitutive expression of CYP3A mRNA in Bama miniature pig tissues
Keywords: RT، رونویسی معکوس; ACTB, β-actin; AMV, Avian myeloblastosis virus; cDNA, DNA complementary to RNA; CYP, cytochrome P450; DEPC, diethylpyrocarbonate; dNTP, deoxyribonucleoside triphosphate; mRNA, messenger RNA; RT, reverse transcriptase; RT-PCR, reverse transcriptase-polymer
Nutritional mismatch in postnatal life of low birth weight rat offspring leads to increased phosphorylation of hepatic eukaryotic initiation factor 2 α in adulthood
Keywords: RT، رونویسی معکوس; MPR, maternal protein restriction; LP, low protein; eIF2α (Ser51), eukaryotic initiation factor-2α (Serine 51); GRP78/94, Glucose regulated protein 78/94; Xbp1, X-box binding protein 1; RT, reverse transcriptase; CHOP, C/EBP homologous protein; cDNA, copy
Role of Motif B Loop in Allosteric Regulation of RNA-Dependent RNA Polymerization Activity
Keywords: RT، رونویسی معکوس; RdRP, RNA-dependent RNA polymerase; MD, molecular dynamics; RT, reverse transcriptase; dsRNA, double-stranded RNA; rNTP, ribonucleoside triphosphate; NNI, non-nucleoside inhibitorantiviral therapy; drug discovery; RNA viruses; RNA-dependent RNA polymerase
Ester prodrugs of acyclic nucleoside thiophosphonates compared to phosphonates: Synthesis, antiviral activity and decomposition study
Keywords: RT، رونویسی معکوس; Nucleotide analogue; Prodrug; Thiophosphonate; Antiviral activity; MetabolismHIV, human immunodeficiency virus; HBV, hepatitis B virus; RT, reverse transcriptase; dNTP, deoxynucleotide; ANP, acyclic nucleoside phosphonate; PMEA, 9-[2-phosphonomethoxyethyl
HLA class II allele frequencies in the Lebanese population
Keywords: RT، رونویسی معکوس; HLA, Human leukocyte antigen; PCR, Polymerase chain reaction; RT, Reverse transcriptase; MHC, Major histocompatibility complex; CD, Celiac disease; MS, Multiple sclerosis; HPV, Human papilloma virus; SCC, Squamous cell carcinoma; SSP, Sequence specific pr
Kinetic analysis of reverse transcriptase activity of bacterial family A DNA polymerases
Keywords: RT، رونویسی معکوس; K4pol, family A DNA polymerase from Thermotoga petrophila strain K4; M1pol, family A DNA polymerase from Thermus thermophilus strain M1; MMLV, Moloney murine leukemia virus; RT, reverse transcriptase; SDS–PAGE, sodium dodecyl sulfate–polyacrylamide gel el
Taro α-galactosidase: A new gene product for blood conversion
Keywords: RT، رونویسی معکوس; α-Gal, α-galactosidase; RT, Reverse transcriptase; RACE, Rapid amplification of cDNA ends; RBC, Red blood cells; ESI-MS-MS, Electrospray ionization-tandem mass spectrometryTaro α-galactosidase; Colocasia esculenta; Pichia pastoris expression; Mass spectro
A new mechanism to ensure integration during LINE retrotransposition: A suggestion from analyses of the 5′ extra nucleotides
Keywords: RT، رونویسی معکوس; ATM, ataxia-telangiectasia mutated; bp, base pair; DSB, DNA double-strand break; kbp, kilo base pair; LINE, long interspersed element; mRNA, messenger RNA; NHEJ, non-homologous end joining; ORF, open reading frame; RT, reverse transcriptase; TPRT, target-
Two CYP3A-like genes in the marine mussel Mytilus edulis: mRNA expression modulation following short-term exposure to endocrine disruptors
Keywords: RT، رونویسی معکوس; Pollution; Ecotoxicology; Mussel; CYP3APCR, polymerase chain reaction; RT, Reverse transcriptase; STW, sewage treatment works; E2, 17beta-estradiol; TBT, tributyltin
GATA-4/-6 and HNF-1/-4 families of transcription factors control the transcriptional regulation of the murine Muc5ac mucin during stomach development and in epithelial cancer cells
Keywords: RT، رونویسی معکوس; Bp, basepair; ED, embryonic day; EMSA, electrophoretic mobility shift assay; HNF, hepatocyte nuclear factor; kb, kilobase; PCR, polymerase chain reaction; PND, post natal day; RT, reverse transcriptase; TF, transcription factorMuc5ac; Stomach; Transcripti
Molecular Biology of the Hepatitis B Virus for Clinicians
Keywords: RT، رونویسی معکوس; Hepadnavirus; rcDNA; pgRNA; HBsAg; genotypeHBV, hepatitis B virus; HCC, hepatocellular cancer; DR, direct repeat; ORF, open reading frames; RT, reverse transcriptase; TP, terminal protein; LHB, large envelope protein; pHSA, poly-human serum albumin; IL, i
Silicon delays Tobacco ringspot virus systemic symptoms in Nicotiana tabacum
Keywords: RT، رونویسی معکوس; AUDPC, Area under the disease progress curve; C, Control (0.1 mM soluble silicon, K2SiO3); DPI, days post-inoculation; ICP-OES, Inductively coupled plasma-optical emission spectroscopy; PCR, polymerase chain reaction; RT, reverse transcriptase; RT-PCR, re
Oxymatrine inhibits hepatitis B infection with an advantage of overcoming drug-resistance
Keywords: RT، رونویسی معکوس; Hsc70, heat-stress cognate 70; HBV, hepatitis B virus; OMTR, oxymatrine; RT, reverse transcriptase; CHB, chronic hepatitis BOxymatrine; Hsc70; Antiviral therapy; Drug resistance; Hepatitis B virus
Functional properties and substrate characterization of human CYP26A1, CYP26B1, and CYP26C1 expressed by recombinant baculovirus in insect cells
Keywords: RT، رونویسی معکوس; RA, retinoic acid; atRA, all-trans retinoic acid; CYP, cytochrome P450; hb5, human cytochrome b5; hOR, cytochrome P450-NADPH reductase; RT, Reverse Transcriptase; RALDH, Retinaldehyde dehydrogenase; BSA, bovine serum albuminRetinoic Acid; Metabolism; CYP2
Synthesis of new 2′-deoxy-2′-fluoro-4′-azido nucleoside analogues as potent anti-HIV agents
Keywords: RT، رونویسی معکوس; 4′-Azido-2′-deoxy-2′-fluoro nucleosides; Anti-HIV activity; Nucleoside reverse transcriptase inhibitor (NRTI); Drug-resistanceIR, infrared; NMR, nuclear magnetic resonance; HRMS, high resolution mass spectrometry; RT, reverse transcriptase; RTMDR, reverse
Accumulation and activation of natural killer cells in local intraperitoneal HIV-1/MuLV infection results in early control of virus infected cells
Keywords: RT، رونویسی معکوس; DN, double negative; DP, double positive; MCMV, murine cytomegalovirus; MuLV, murine leukemia virus; RT, reverse transcriptase; SIV, simian immunodeficiency virusNK cell; HIV-1; Murine leukemia virus; Acute infection; CD27; Mac-1
T cell hybridomas to study MHC-II restricted B-cell receptor-mediated antigen presentation by human B cells
Keywords: RT، رونویسی معکوس; APC, antigen presenting cell; BCR, B cell receptor; TCR, T-cell receptor; RT, reverse transcriptase; HAT, hypoxanthine/aminopterin/thymadineB cells; Antigen presentation; B cell receptor; MHC class II
Acyclic nucleoside thiophosphonates as potent inhibitors of HIV and HBV replication
Keywords: RT، رونویسی معکوس; Modified nucleotide; Thiophosphonate; Antiviral activity; HIV; HBVHIV, human immunodeficiency virus; HBV, hepatitis B virus; RT, reverse transcriptase; NRTIs, nucleoside RT inhibitors; NtRTIs, nucleotide RT inhibitors; dNTP, deoxynucleotide; ANPs, acyclic
Silencing of a putative inner arm dynein heavy chain results in flagellar immotility in Trypanosoma brucei
Keywords: RT، رونویسی معکوس; RNAi, RNA interference; HC, heavy chain; kb, kilobase; aa, amino acid; PCR, polymerase chain reaction; PFR, paraflagellar rod; ATP, adenosine triphosphate; RT, reverse transcriptase; DAPI, 4′,6-diamidino-2-phenylindole; DIC, differential interference cont
Reverse transcriptase mutation K65N confers a decreased replication capacity to HIV-1 in comparison to K65R due to a decreased RT processivity
Keywords: RT، رونویسی معکوس; HIV-1, Human immunodeficiency virus type 1; RT, Reverse transcriptase; TFV, tenofovir; TDF, tenofovir disoproxil fumarate; ddI, didanosineReplication; Attenuation; RT mutation; K65R, Lys65Arg; K65N, Lys65Asn
Variable influence of mutational patterns in reverse-transcriptase domain on replication capacity of hepatitis B virus isolates from antiviral-experienced patients
Keywords: RT، رونویسی معکوس; HBV, hepatitis B virus; HBsAg, hepatitis B surface antigen; RT, reverse transcriptase; Pol, polymerase; PCR, polymerase chain reaction; cccDNA, covalently closed circular DNA; NCBI, National center for biotechnology information; CT, threshold cycle; CV, c
Egr-1 regulates the transcriptional repression of mouse δ-aminolevulinic acid synthase 1 by heme
Keywords: RT، رونویسی معکوس; ALAS, δ-aminolevulinate synthase; PGC-1α, peroxisome proliferator-activated receptor γ coactivator 1 α; DMEM, Dulbecco's modified Eagle's medium; FCS, fetal calf serum; SA, succinylacetone; HRE, heme-responsive element; RT, reverse transcriptase; EMSA, el
Evolutionary pattern of full hepatitis B virus genome during sequential nucleos(t)ide analog therapy
Keywords: RT، رونویسی معکوس; CHB, chronic hepatitis B; HBV, hepatitis B virus; NUC, nucleos(t)ide analog; RT, reverse transcriptase; LAM, lamivudine; ADV, adefovir dipivoxil; LDT, telbivudine; ETV, entecavir; ALT, alanine amino transferase; ORF, open reading frame; HBeAg, hepatitis B
Mechanistic insights into the roles of three linked single-stranded template binding residues of MMLV reverse transcriptase in misincorporation and mispair extension fidelity of DNA synthesis
Keywords: RT، رونویسی معکوس; MMLV, Moloney murine leukemia virus; RT, reverse transcriptase; HIV-1, human immunodeficiency virus type 1; WT, wide typeFidelity; HIV-1; Kinetics; Moloney murine leukemia virus; Reverse transcriptase; Structure–function
The Reverse Transcriptase Encoded by the Non-LTR Retrotransposon R2 Is as Error-Prone as That Encoded by HIV-1
Keywords: RT، رونویسی معکوس; RT, reverse transcriptase; LTR, long terminal repeat; HIV-1, human immunodeficiency virus type 1; MuLV, murine leukemia virus; AMV, avian myeloblastosis virus; TPRT, target-primed reverse transcription; T/P, template/primerreverse transcriptases; retrotra
Secondary Structure of the HIV Reverse Transcription Initiation Complex by NMR
Keywords: RT، رونویسی معکوس; HIV; reverse transcriptase; initiation complex; RNA; NMRHIV, human immunodeficiency virus; RT, reverse transcriptase; PBS, primer binding site; TROSY, transverse relaxation optimized spectroscopy; NOESY, nuclear Overhauser enhancement spectroscopy; NOE, n
Identification and expression profiling of Ceratitis capitata genes coding for β-hexosaminidases
Keywords: RT، رونویسی معکوس; Cc, Ceratitis capitata; EST, Expression Sequence Tag; MYA, Million Years Ago; CT, Cross Threshold; PCR, polymerase chain reaction; RT, reverse transcriptase; ISH, in situ hybridization; FISH, fluorescent in situ hybridization; TSA, tyramide signal amplifi
Mutations in the Gene Encoding C8orf38 Block Complex I Assembly by Inhibiting Production of the Mitochondria-Encoded Subunit ND1
Keywords: RT، رونویسی معکوس; mtDNA, mitochondrial DNA; BN-PAGE, blue native-PAGE; COPP, complex I phylogenetic profile; GFP, green fluorescent protein; PK, proteinase K; 2D, two-dimensional; RT, reverse transcriptase; MLPA, multiplex ligation-dependent probe amplification; DMEM, Dulb
Complete Modification Maps for the Cytosolic Small and Large Subunit rRNAs of Euglena gracilis: Functional and Evolutionary Implications of Contrasting Patterns between the Two rRNA Components
Keywords: RT، رونویسی معکوس; SSU, small subunit; LSU, large subunit; Nm, ribose-methylated nucleoside; Ψ, pseudouridine; snoRNA, small nucleolar RNA; RT, reverse transcriptase; TLC, thin-layer chromatography; m5U, 5-methyluridine; m1Ψ, 1-methylpseudouridine; m1acp3Ψ, 1-methyl-3-(3-am
Magnetic-silica based nucleic acid extraction for Human Immunodeficiency Virus Type-1 drug-resistance testing in low viremic patients
Keywords: RT، رونویسی معکوس; HIV-1, Human Immunodeficiency Virus Type-1; NeM, NucliSENS easyMAG; PCR, polymerase chain reaction; P, protease; RT, reverse transcriptase; PI, protease inhibitor; NRTI, nucleoside reverse transcriptase inhibitor; NNRTI, non-nucleoside reverse transcripta
Hypomethylation of the interleukin-10 gene in breast cancer tissues
Keywords: RT، رونویسی معکوس; Interleukin-10; Methylation; Breast cancerCpG, cytosine guanine dinucleotide; IL-10, interleukin-10; RT, reverse transcriptase; PCR, polymerase chain reaction
Expression of HYAL1 and Survivin RNA as Diagnostic Molecular Markers for Bladder Cancer
Keywords: RT، رونویسی معکوس; urinary bladder; carcinoma; tumor markers; biological; urine; gene expressionNPV, negative predictive value; PCR, polymerase chain reaction; PPV, positive predictive value; RT, reverse transcriptase
A novel ryanodine receptor expressed in pancreatic islets by alternative splicing from type 2 ryanodine receptor gene
Keywords: RT، رونویسی معکوس; Cyclic ADP-ribose; Ryanodine receptor; Alternative splicing; Pancreatic isletscADPR, cyclic ADP-ribose; RyR, ryanodine receptor; PCR, polymerase chain reaction; RT, reverse transcriptase; RACE, rapid amplification of cDNA end; HBSS, Hank’s balanced salt s
Development of a lentiviral vector system to study the role of the Andes virus glycoproteins
Keywords: RT، رونویسی معکوس; ANDV, Andes virus; CMV, Cytomegalovirus; HIV, Human immunodeficiency virus; GFP, green fluorescent protein; GPC, glycoprotein precursor; mβCD, methyl-β-cyclodextrin; RT, reverse transcriptase; SIV, Simian immunodeficiency virus; VSV, Vesicular stomatitis
Formation of the tRNALys packaging complex in HIV-1
Keywords: RT، رونویسی معکوس; HIV-1, human immunodeficiency virus type 1; MA, matrix protein; CA, capsid protein; NC, nucleocapsid protein; PR, protease; RT, reverse transcriptase; IN, integrase; PBS, primer binding site; MuLV, murine leukemia virus; AMV, avian myeloblastosis virus; a
Genetic diversity of Ty1-copia retrotransposons in a wild species of Cucumis (C. hystrix)
Keywords: RT، رونویسی معکوس; LTR, long terminal repeat; ORF, open reading frame; PCR, polymerase chain reaction; RT, reverse transcriptase; RT-PCR, reverse transcription PCR; TE, transposable elementCucumis hystrix; Retrotransposons; Reverse transcriptase; Heterogeneity; Transcriptio