دانلود مقالات ISI درباره Saha + ترجمه فارسی

Interplay between histone acetylation/deacetylation and poly(ADP-ribosyl)ation in the development of ischemic tolerance in vitro

Keywords: Ischemia tolerance; Preconditioning; NMDA; Histone acetylation/deacetylation; Poly(ADPribosyl)ation; HDAC inhibitors; HAT; histone acetyl transferase; HDAC; histone deacetylase; OGD; oxygen-glucose deprivation; SAHA; suberoylanilide hydroxamic acid; PARP;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Regulation of T-type calcium channel expression by sodium butyrate in prostate cancer cells

Keywords: LNCaP; lymph node carcinoma of the prostate; NaBu; sodium butyrate; NED; neuroendocrine differentiation; SAHA; suberoylanilide hydroxamic acid; 5׳-azaC; 5-azacytidine; NNC 55-0396 (PubChem CID: 11957578); Paclitaxel (PubChem CID: 36314); Sodium butyrate

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

In vitro and in vivo evaluation of novel cinnamyl sulfonamide hydroxamate derivative against colon adenocarcinoma

Keywords: ACFs; aberrant crypt foci; AO/EB; acridine orange/ethidium bromide; CPCSEA; Committee for the Purpose of Control and Supervision of Experiments on Animals; CMC; carboxymethylcellulose; DMEM; Dulbecco's minimum essential media; DMSO; dimethyl sulfoxide;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Thymosin-β4 is a determinant of drug sensitivity for Fenretinide and Vorinostat combination therapy in neuroblastoma

Keywords: Thymosin-β4 (Tβ4); 4-HPR; SAHA; Neuroblastoma; Histone deacetylase inhibitors and retinoic acid receptor alpha (RARα);

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2015 سفارش ترجمه

SAHA triggered MET activation contributes to SAHA tolerance in solid cancer cells

Keywords: SAHA; MET; XL184; Combination therapy;

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2015 سفارش ترجمه

Treatment of chronically FIV-infected cats with suberoylanilide hydroxamic acid

Keywords: FIV; SAHA; Antilatency therapy; HIV; Animal model; HDAC inhibitor;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2014 سفارش ترجمه

Prenatal alcohol exposure causes the over-expression of DHAND and EHAND by increasing histone H3K14 acetylation in C57 BL/6 mice

Keywords: Prenatal alcohol exposure; Histone H3K14 acetylation; Curcumin; SAHA; DHAND; EHAND

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Pentyl-4-yn-VPA, a histone deacetylase inhibitor, ameliorates deficits in social behavior and cognition in a rodent model of autism spectrum disorders

Keywords: Social cognition; SAHA; VPA; H3K9ac

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Suberoylanilide hydroxamic acid radiosensitizes tumor hypoxic cells in vitro through the oxidation of nitroxyl to nitric oxide

Keywords: SAHA; Valproic acid; Tempol; Pulse radiolysis; HNO; NO; Nitroxide; Kinetics; Free radicals;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

SAHA-based novel HDAC inhibitor design by core hopping method

Keywords: SAHA; Core hopping; Docking; ADMET; Molecular dynamics simulation;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

The discovery of colchicine-SAHA hybrids as a new class of antitumor agents

Keywords: Colchicine; SAHA; HDAC; Tubulin; Hybrid;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Radionuclide labeling and evaluation of candidate radioligands for PET imaging of histone deacetylase in the brain

Keywords: Carbon-11; Positron emission tomography; SAHA; Brain; Epigenetics; Brain permeability;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Epigenetic regulation of microRNA expression in renal cell carcinoma

Keywords: ccRCC; clear cell renal cell carcinoma; DNMT; DNA methyltransferase; HDAC; histone deacetylase; miR; microRNA; 5-Aza-2′dC; 5-aza-2′-deoxycytidine; SAHA; suberoylanilide hydroxamic acid; RIN; RNA integrity numbers; SDS-PAGE; sodium dodecyl sulphateâ€

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Prenatal exposure to suberoylanilide hydroxamic acid perturbs corticogenesis

Keywords: HDAC inhibitor; Histone acetylation; SAHA; Neurogenesis; Corticogenesis; Neural stem cells;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Nicotine primes the effect of cocaine on the induction of LTP in the amygdala

Keywords: Nicotine; Cocaine; Gateway hypothesis; LTP; Amygdala; SAHA; Histone acetylation;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Differential regulation of Bdnf expression in cortical neurons by class-selective histone deacetylase inhibitors

Keywords: HDAC; BDNF; SAHA; MS-275; MC1568; CRE

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Chemical regulation of mid- and late-life longevities in Drosophila

Keywords: HDAcI, histone deacetylase inhibitors; NaBu, sodium butyrate; SAHA, suberoylanilide hydroxamic acid or vorinostatSodium butyrate; SAHA; HDAc inhibitors; Longevity regulation; Drosophila; Stage-specific drug sensitivity; Healthy senescence

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Vitamin D in thyroid tumorigenesis and development

Keywords: 1,25(OH)2D3; 1α,25-dihydroxyvitamin D3; 25-OHD3; 25-hydroxyvitamin D3; ATC; anaplastic thyroid cancer; CDK; cyclin-dependent kinase; CDKI; cyclin-dependent kinase inhibitor; CEA; carcinoembryogenic antigen; CT; calcitonin; CYP24A1; 24-hydroxylase; CYP27B

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2013 سفارش ترجمه

Suberoylanilide hydroxamic acid (SAHA) inhibits EGF-induced cell transformation via reduction of cyclin D1 mRNA stability

Keywords: SAHA; cyclin D1 mRNA stability; Cell transformation

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Valproic acid increases white matter repair and neurogenesis after stroke

Keywords: BSA; bovine serum albumin; BrdU; bromodeoxyuridine; CNPase; 2″,3″-cyclic nucleotide 3′-phosphodiesterase; DAPI; 4′,6′-diamidino-2-phenylindole; DCX; doublecortin; GFAP; glial fibrillary acidic protein; GLT1; glutamate transporter 1; HDAC; histon

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Synthesis and biochemical analysis of 2,2,3,3,4,4,5,5,6,6,7,7-dodecafluoro-N-hydroxy-octanediamides as inhibitors of human histone deacetylases

Keywords: Histone deacetylase; Histone deacetylase inhibitors; SAHA; Vorinostat; Oncology;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Histone modifications as a pathogenic mechanism of colorectal tumorigenesis

Keywords: AP2A1; adaptor related protein complex 2, subunit alpha 1; APAF1; apoptotic protease activating factor 1; APC; adenomatous polyposis coli; BRCA1, 2; breast cancer 1, 2; CARM1; co-activator-associated arginine methyltransferase 1; CBP; cAMP-responsive elem

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

Proteins implicated in the increase of adhesivity induced by suberoylanilide hydroxamic acid in leukemic cells

Keywords: SAHA; Adhesion; Cofilin; Vimentin; PAK; HDAC inhibitor

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2012 سفارش ترجمه

Acetylation of EGF receptor contributes to tumor cell resistance to histone deacetylase inhibitors

Keywords: EGFR; CBP; Acetylation; Phosphorylation; SAHA;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

The hallmarks of CDKN1C (p57, KIP2) in cancer

Keywords: AML; acute myeloid leukemia; Bcl-2; B-cell lymphoma 2; Bcl-xL; B-cell lymphoma-x long; BCR-ABL; breakpoint cluster region-V-abl Abelson murine leukemia viral oncogene homolog 1; bHLH; basic helix-loop-helix; BWS; Beckwith-Wiedemann Syndrome; CDK; cy

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Determination of HS270, a new histone deacetylase inhibitor, in rat plasma by LC–MS/MS—Application to a preclinical pharmacokinetic study

Keywords: Histone deacetylase inhibitor; HS270; SAHA; Liquid chromatography/tandem mass spectrometry (LC–MS/MS); Pharmacokinetics

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Synthesis and evaluation of aliphatic-chain hydroxamates capped with osthole derivatives as histone deacetylase inhibitors

Keywords: Histone deacetylase; SAHA; LBH-589; Osthole; Molecular modeling

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

1,25-Dihydroxyvitamin D3 and a superagonistic analog in combination with paclitaxel or suberoylanilide hydroxamic acid have potent antiproliferative effects on anaplastic thyroid cancer

Keywords: Thyroid; Cancer; Vitamin D; Nonsteroidal analog; SAHA; Paclitaxel

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Targeting autophagy during cancer therapy to improve clinical outcomes

Keywords: AMPK; AMP activated protein kinase; ATG; autophagy-related genes; Bif-1; endophilin B1; BNIP3; Bcl-2/adenovirus E1B 19 kDa-interacting protein; CML; chronic myeloid leukemia; CQ; chloroquine; DAP1; death-associated protein 1; HCQ; hydroxychloroquine; HDA

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

The synthesis and evaluation of N1-(4-(2-[18F]-fluoroethyl)phenyl)-N8-hydroxyoctanediamide ([18F]-FESAHA), A PET radiotracer designed for the delineation of histone deacetylase expression in cancer

Keywords: PET; Histone deacetylase; Hydroxamic acid; SAHA; [18F]-FAHA; [18F]-FESAHA

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2011 سفارش ترجمه

Selenium-containing analogs of SAHA induce cytotoxicity in lung cancer cells

Keywords: SAHA; HDAC; Lung cancer

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

Valproic acid stimulates clusterin expression in human astrocytes: Implications for Alzheimer's disease

Keywords: Alzheimer's disease; Clusterin; Epigenetics; SAHA; Valproate; Vorinostat

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Suberoylanilide hydroxamic acid (SAHA) potentiates paclitaxel-induced apoptosis in ovarian cancer cell lines

Keywords: Ovarian cancer; Histone deacetylase inhibitor; SAHA; Paclitaxel; Survivin; Bad

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

In vitro and in vivo histone deacetylase inhibitor therapy with vorinostat and paclitaxel in ovarian cancer models: Does timing matter?

Keywords: Histone deacetylase inhibitor; Mouse ovarian cancer model; Vorinostat; SAHA

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Actions of the anti-cancer drug suberoylanilide hydroxamic acid (SAHA) on human breast cancer cytoarchitecture in silicon microstructures

Keywords: Cancer; Cytoskeleton; MDA-MB-231 cells; SAHA; Silicon microstructures; 3-D

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Suberoylanilide Hydroxyamic Acid Modification of Chromatin Architecture Affects DNA Break Formation and Repair

Keywords: SAHA; Sublethal damage repair; DNA double-strand breaks; DNA rearrangements; Radiosensitizer;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Histone deacetylase inhibitors prevent activation of tumour-reactive NK cells and T cells but do not interfere with their cytolytic effector functions

Keywords: Histone deacetylase inhibitors; SAHA; NK activation; Priming; Cytotoxicity

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

The inhibitors of histone deacetylase suberoylanilide hydroxamate and trichostatin A release nitric oxide upon oxidation

Keywords: HDAC; SAHA; Oxidation; NO; EPR; Free radicals

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Induction of Foxp3+ regulatory T cells with histone deacetylase inhibitors

Keywords: HDAC, histone deacetylase; SAHA, suberoylanilide hydroxamic acid; CTLA-4, cytotoxic T lymphocyte-associated protein 4; GITR, glucocorticoid-induced TNF family related receptor; DNFB, 2,4-dinitro-1-fluorobenzeneHDAC; MS-275; SAHA; Regulatory T cells; Foxp3

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Distinct HIC1-SIRT1-p53 Loop Deregulation in Lung Squamous Carcinoma and Adenocarcinoma Patients

Keywords: 5-aza-dC; 5-aza-2′-deoxycytidine; AD; adenocarcinoma; DBC1; deleted in breast cancer 1; H3K9me; histone H3 methylated at Lys9; H3K9ac; histone H3 acetylated at Lys9; HIC1; hypermethylation in cancer 1; MeCP2; methyl CpG binding protein 2; NSCLC; non-sma

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Cell cycle and apoptotic effects of SAHA are regulated by the cellular microenvironment in HCT116 multicellular tumour spheroids

Keywords: Spheroids; Tumour microenvironment; SAHA; Cell cycle; Cytotoxicity; 3D imaging

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Development of vorinostat: Current applications and future perspectives for cancer therapy

Keywords: Histone deacetylase; HDAC; Epigenetics; Suberoylanilide hydroxamic acid; SAHA; Vorinostat

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Additive effect of apicidin and doxorubicin in sulfatase 1 expressing hepatocellular carcinoma in vitro and in vivo

Keywords: Akt; protein kinase Akt; CHAPs; cyclic-hydroxamic-acid-containing peptides; DAPI; 4,6-diamidino-2-phenylidole dihydrochloride; Erk; extracellular signal-regulated kinase; HCC; hepatocellular carcinoma; HDAC; histone deacetylase; MAPK; mitogen activated pr

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Acetylation of FoxO1 Activates Bim Expression to Induce Apoptosis in Response to Histone Deacetylase Inhibitor Depsipeptide Treatment

Keywords: CBP; cyclic adenosine monophosphate-responsive element-binding protein-binding protein; FHL2; four-and-a-half LIM-domain protein 2; FoxO1; forkhead box class O1; HDAC inhibitor; histone deacetylase inhibitor; PI3-K; phosphatidylinositol 3-kinase; PKB/Akt;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2009 سفارش ترجمه

The histone deacetylase inhibitor suberoylanilide hydroxamic acid sensitises human hepatocellular carcinoma cells to TRAIL-induced apoptosis by TRAIL-DISC activation

Keywords: TRAIL; SAHA; HCC cells; DR5; NF-kB; Akt

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2009 سفارش ترجمه

Chemically distinct HDAC inhibitors prevent adipose conversion of subcutaneous human white preadipocytes at an early stage of the differentiation program

Keywords: C/EBPα; CCAAT/enhancer-binding protein-α; FABP4/aP2; adipose specific fatty acid binding protein; FCS; foetal calf serum; GPDH; Sn-glycerol-3-phosphate dehydrogenase; HBSS; Hank's balanced salt solution; HDAC; histone deacetylase; HDACi; histone deacety

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2009 سفارش ترجمه

A Rationally Designed Histone Deacetylase Inhibitor with Distinct Antitumor Activity against Ovarian Cancer

Keywords: HDAC; histone deacetylase; HDACI; histone deacetylase inhibitor; SAHA; suberoylanilide hydroxamic acid; VPA; valproic acid; AE1/AE3; a mixture of two monoclonal antibodies (AE1 and AE3), with broad specificity against cytokeratins; NOSE; normal ovarian su

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2009 سفارش ترجمه

The R6 lines of transgenic mice: A model for screening new therapies for Huntington's disease

Keywords: AdBDNF/AdNoggin; adenoviral BDNF + adenoviral noggin; AIF; apoptosis inducing factor; asialoEPO; asialoerythropoietin; BDNF; brain-derived neurotrophic factor; CGS; CGS21680; DA; dopamine; DARPP-32; dopamine and cyclic-adenosine monophosphate regulated ph

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2009 سفارش ترجمه

Development of a fluorescence polarization based assay for histone deacetylase ligand discovery

Keywords: HDAC; Histone deacetylases; Suberoylanilide hydroxamic acid; SAHA; Fluorescence polarization; Ligand discovery; High-throughput screening

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2008 سفارش ترجمه

Class II histone deacetylases play pivotal roles in heat shock protein 90-mediated proteasomal degradation of vascular endothelial growth factor receptors

Keywords: Vascular endothelial growth factor receptor; Histone deacetylase inhibitor; Proteasome; Heat shock protein; SAHA; LAQ824

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه