دانلود مقالات ISI درباره Samr1 + ترجمه فارسی

پروینسولین از طریق تخریب شناختی مرتبط با سن از طریق مسیرهای همگرایی ضد التهابی محافظت می کند

Proinsulin protects against age-related cognitive loss through anti-inflammatory convergent pathways

Keywords: Proinsulin; Therapy; Adeno-associated virus vector; Cognitive loss; Inflammaging; A2M; α-2-macroglobulin; Aβ; amyloid β peptides; AβPP; amyloid β protein precursor; AAV; adeno-associated virus; AD; Alzheimer's disease; Akt; protein kinase B; ANOVA; a

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2017 سفارش ترجمه

متابولومیک در بیماری آلزایمر: نیاز به سیستم عامل های مکمل برای شناسایی بیومارکرها برای شناسایی آسیب شناسی زیر زمینی

Metabolomics in Alzheimer's disease: The need of complementary analytical platforms for the identification of biomarkers to unravel the underlying pathology

Keywords: Aβ; amyloid-beta; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; APCI; atmospheric pressure chemical ionization; APOE; apolipoprotein E; APP; amyloid precursor protein; APPI; atmospheric pressure photoionization; CE; capillary electrophor

دانلود رایگان متن کامل مقاله ISI 57 صفحه سال انتشار : 2017 سفارش ترجمه

گیرنده بیان شده بر روی سلول های میلوئیدی 2 نابود کننده باعث افزایش التهاب عصبی و کمبود شناختی مرتبط با پیری در 8 موش صحرایی موش صحرایی می شود

Triggering receptor expressed on myeloid cells 2 knockdown exacerbates aging-related neuroinflammation and cognitive deficiency in senescence-accelerated mouse prone 8 mice

Keywords: TREM2; Aging; Neuroinflammation; Alzheimer's disease; Cognitive deficiency; SAMP8; SAMR1;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Gut flora-dependent metabolite Trimethylamine-N-oxide accelerates endothelial cell senescence and vascular aging through oxidative stress

Keywords: Ach; acetylcholine; ALT; alanine aminotransferase; AST; aspartate aminotransferase; BMI; body mass index; Collagen/MA; the ratio of collagen content to media area; CPDL; cumulative population doubling level; CVD; cardiovascular disease; DBP; diastolic blo

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2018 سفارش ترجمه

Effects of vitamin D and resveratrol on metabolic associated markers in liver and adipose tissue from SAMP8 mice

Keywords: AD; Alzheimer's disease; AMPK; AMP-activated protein kinase; APP; amyloid precursor protein; AUC; area under the curve; ER; endoplasmic reticulum; EPI; epididymal; FFAs; free fatty acids; GRP78; 78 kDa glucose-regulated protein; GTT; glucose tolerance te

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2017 سفارش ترجمه

Protective effects of NMDA receptor antagonist, memantine, against senescence of PC12 cells: A possible role of nNOS and combined effects with donepezil

Keywords: Aß; amyloid ß; Ach; acetylcholine; AD; Alzheimer disease; CNS; central nervous system; DAF-2; diaminofluorescein-2; DAPI; 4′, 6-diamidino-2-phenylindole; e, i, nNOS; endothelial, inducible, neuronal nitric oxide synthase; HUVEC; human umbilical vein e

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Caloric restriction, resveratrol and melatonin: Role of SIRT1 and implications for aging and related-diseases

Keywords: Aβ; amyloid β protein; AMPK; adenosine monophosphate activated protein kinase; CGNs; cerebellar granule neurons; ETC; electron transport chain; H2O2; hydrogen peroxide; HO-1; heme oxygenase-1; LXR; liver X receptor; MAPK; mitogen-activated protein kinas

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2015 سفارش ترجمه

Vitamin C and lifespan in model organisms

Keywords: ApoE; apolipoprotein E; DOG; 2-deoxy-D-glucose; GLO; L-gulonolactone oxidase; HFHC; high fat/high cholesterol; Nrf2; nuclear factor like 2; ODS; Osteogenic Disorder Shionogi; PGC; peroxisome proliferator-activated receptor gamma coactivator; ROS; reactive

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Age-dependent increases in the oxidative damage of DNA, RNA, and their metabolites in normal and senescence-accelerated mice analyzed by LC-MS/MS: Urinary 8-oxoguanosine as a novel biomarker of aging

Keywords: AD; Alzheimer disease; DFOM; deferoxamine mesylate; ESCODD; European Standard Committee on Oxidative DNA Damage; dGsn; 2′-deoxyguanosine; Gsn; guanosine; 8-oxoguanine; 8-oxo-7,8-dihydroguanine; 8-oxo-dGsn; 8-oxo-7,8-dihydro-2′-deoxyguanosine; 8-oxo-Gs

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Intranasal administration of TAT-haFGF14-154 attenuates disease progression in a mouse model of Alzheimer's disease

Keywords: ACh; acetylcholine; AChE; acetylcholinesterase; AD; Alzheimer's disease; Aβ1-42; β-amyloid protein1-42; BBB; blood-brain barrier; BCA; bicinchoninic acid; ChAT; choline acetyltransferase; ELISA; enzyme-linked immunosorbent assay; GSH-Px; glutath

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2012 سفارش ترجمه

Learning capabilities and CA1-prefrontal synaptic plasticity in a mice model of accelerated senescence

Keywords: Aging; Classical eyelid conditioning; Object recognition; SAMP8; SAMR1; LTP; Activity-dependent synaptic plasticity;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2012 سفارش ترجمه

Disturbance of rapid eye movement sleep in senescence-accelerated mouse prone/8 mice is improved by retinoic acid receptor agonist Am80 (tamibarotene)

Keywords: sleep; aging; vitamin A; cholinergic system; transthyretin; ACh; acetylcholine; ANOVA; analysis of variance; ChAT; choline acetyltransferase; EDTA Na2; disodium ethylenediaminetetraacetic acid; EEG; electroencephalogram; EMG; electromyogram; GAPDH; glycer

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Amelioration of cognitive ability in senescence-accelerated mouse prone 8 (SAMP8) by intra-bone marrow-bone marrow transplantation

Keywords: IBM-BMT; intra-bone marrow-bone marrow transplantation; SAMP8; senescence-accelerated mouse prone 8; SAMR1; senescence-accelerated mouse resistant 1; AD; Alzheimer's disease; HSCs; hemopoietic stem cells; MSCs; mesenchymal stem cells; HO-1; heme oxygenase

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Age-related expression of calcium/calmodulin-dependent protein kinase II A in the hippocampus and cerebral cortex of senescence accelerated mouse prone/8 mice is modulated by anti-Alzheimer's disease drugs

Keywords: Alzheimer's disease; calcium/calmodulin-dependent protein kinase II-α; senescence accelerated mouse; anti-AD drugs; AD; Alzheimer's disease; ANOVA; analysis of variance; BW; Ba-Wei-Di-Huang decoction; CaMKII; calcium/calmodulin-dependent protein kinase I

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Senescence accelerated mouse strain is sensitive to neurodegeneration induced by mild impairment of oxidative metabolism

Keywords: Aβ; β-Amyloid peptide; AD; Alzheimer's disease; APP; Amyloid precursor protein; mt; mammillothalamic tract; NeuN; Neuronal specific nuclear protein; SAMP8; Senescence accelerated prone 8; SAMR1; Senescence accelerated resistant 1; SmTN; Submedial thalam

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Age-related difference in nociceptive behavior between SAMP6 and SAMR1 strains

Keywords: von Frey test; Hot plate test; Formalin paw test; SAMR1; SAMP6;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2008 سفارش ترجمه

Sleep wake profile and EEG spectral power in young or old senescence accelerated mice

Keywords: Sleep-wake cycle; Aging; Senescence accelerated mouse; SAMP8; SAMR1; EEG theta rhythm;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

REM sleep control during aging in SAM mice: a role for inducible nitric oxide synthase

Keywords: Sleep-wake cycle; Aging; Senescence Accelerated Mouse; SAMP8; SAMR1; REM sleep; Nitric oxide; Inducible nitric oxide synthase; Inhibitor;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه