Keywords: Mesenchymal stem cells; SASP; Stress-induced senescence; Signaling pathway; DNA damage response; Senescence propagation;
مقالات ISI (ترجمه نشده)
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Keywords: H2DCFDA; 2â²,7â²-dichlorofluorescein diacetate; 5-Aza-dC; 5-aza-2-deoxycytidine; CDCFDA; 5-(and-6)-carboxy-2â²,7â²-dichlorofluorescein diacetate; AdhSOD3; adenoviral vector containing human ECSOD cDNA; GFP; adenovirus containing green fluorescent prot
Keywords: Atherosclerosis; Sterile inflammation; Damage-associated molecular patterns; NLRP3 inflammasome; Immune cells; AAASP; age-associated arterial secretory phenotype; AIM; Absent in Melanoma; ALRs; AIM 2-like receptors; AGER/RAGE; advanced glycation endproduc
Keywords: Senescence; Lung; SASP; Extracellular vesicles; Exosome; Autophagy;
Keywords: α-CGRP; alpha-calcitonin gene related peptide; Ang; angiopoietin; AE2; anion exchanger 2; ADP; adenosine diphosphate; ADPKD; autosomal dominant polycystic kidney disease; ATP; adenosine triphosphate; ASBT; sodium-dependent bile acid transporter; AQP; aqu
Keywords: QPA; quaternary protoberberine alkaloid; TF; transcriptional factor; UC; ulcerative colitis; IEC-6; intestinal epithelial cell-6; XBP1; X-box-binding protein 1; MIC; minimal inhibitory concentration; SAR; structure-activity relationship; SASP; Sulfasalazi
Keywords: ALP; alkaline phosphatase; BMPs; bone morphogenetic proteins; C/EBPÃ; CCAAT/enhancer binding protein beta; CIA; collagen II induced arthritis; CTD; C-terminal domain; Cx43; connexin43; Cxs; connexins; DMOADs; disease-modifying osteoarthritis drugs; ECM;
Keywords: Type 2 diabetes; Metaflammation; Inflammageing; Immune system; Immunometabolism; Senescence; SASP; Epigenetic alterations; microRNA; Mediterranean diet; Fasting regimen; Microbiota; Antihyperglycaemic agent; Hyperglycaemic memory; Oxidative stress;
Keywords: CDK; cyclin-dependent kinase; CKD; chronic kidney disease; DR; dietary restriction; ESRD; end stage renal disease; FOXO4; Forkhead BOX O 4; HSP-90; heat shock protein 90; IF; interstitial fibrosis; IL-6; interleukin-6; IRI; ischemia reperfusion injury; NS
Keywords: AKI; acute kidney injury; α-SMA; αâsmooth muscle actin; CKD; chronic kidney disease; ECM; extracellular matrix; CTGF; (connective tissue growth factor); DC; dendritic cells; DTR; diphtheria toxin receptor; EGF; epidermal growth factor; EMT; epithelial
Keywords: DSS; dextran sulfate sodium; UC; ulcerative colitis; Pal; palmatine; IBD; inflammatory bowel disease; UPLC-MS; ultra-performance liquid chromatography coupled with mass spectrometry; DAI; assessment of disease activity index; SASP; sulfasalazine; H&E; hem
Keywords: BME; Basal Medium Eagle; CCL2; C-C motif chemokine ligand 2; CM; conditioned medium; cSCC; cutaneous squamous cell carcinoma; CTGF; connective tissue growth factor; CXCL1; C-X-C motif chemokine ligand 1; DMEM; Dulbecco's modified Eagle's medium; EGF;
Keywords: ERK; extracellular signal regulated kinase; FXR; farsenoid X receptor; HCC; hepatocellular carcinoma; HSCs; hepatic stellate cells; IL1β; Interleukin 1 beta; IL18; Interleukin 18; IKKβ; inhibitor of nuclear factor kappa-B kinase subunit beta; JAK; Janus
Keywords: SASP; senescence-associated secretory phenotype; OA; osteoarthritis; COPD; chronic obstructive pulmonary disease; IPF; idiopathic pulmonary fibrosis; ROS; reactive oxygen species; DDR; DNA damage response; ATM; ataxia-telangiectasia mutated; ATR; ataxia-t
Keywords: ac; acetylation; BET; bromodomain and extra terminal family proteins; BMP7; bone morphogenic protein 7; BRD4; bromodomain-containing protein 4; bp; base pairs; CKD; chronic kidney disease; CTGF; connective tissue growth factor; DDR; DNA damage response; D
Keywords: Aging; B cells; Inflammation; Vaccine responses; SASP;
Keywords: constrictive pericarditis; pericardial interstitial cell; senescence; structural remodeling; BMP; bone morphogenetic protein; DMEM; Dulbecco's modified Eagle's medium; ECM; extracellular matrix; IPCP; idiopathic and postsurgical constrictive pericarditis;
Keywords: ACL; ATP citrate lyase; AMPK; adenosine monophosphate kinase; ARG1; l-arginine-metabolizing enzyme arginase 1; BCAA; branched-chain amino acid; Bcl2; B-cell lymphoma 2; CAF; cancer-associated fibroblast; CIC; cancer-initiating cell; COX2; cytochrome oxida
Keywords: Cell senescence; Cell cycle arrest; SASP; Rapamycin; Nrf2;
Keywords: prostatectomy; incontinence pads; robotics; urinary; records as topic; QOL; quality of life; RARP; robot-assisted radical prostatectomy; SASP; self-addressed stamped postcard;
Keywords: Aβ; amyloid-beta; AD; Alzheimer's disease; ADCC; antibody dependent cell-mediated cytotoxicity; ALS; amyotrophic lateral sclerosis; APCs; antigen presenting cells; APOE; apolipoprotein E; APP; amyloid precursor protein; APP/PS1; amyloid precursor prote
Keywords: PG; proteoglycan; IDD; intervertebral disc degeneration; SASP; senescence-associated secretory phenotype; SAβ-gal; senescence-associated β-galactosidase; MMP; Matrix metalloproteinase; ADAMTS; A disintegrin and metalloproteinase with thrombospondin moti
Keywords: Senescence; Amniochorion; Sterile inflammation; Pregnancy; Preterm birth; Cell free fetal DNA; DAMPs; SASP;
Keywords: ATM; ataxia telangiectasia mutated; DDR; DNA-damage response; MAPK; mitogen-activated protein kinase; MMP; matrix metalloproteinase; mTOR; mammalian target of rapamycin; PKD1; protein kinase D1; SASP; senescence-associated secretory phenotype; SCC; squamo
Keywords: Autophagy; Senescence; Oxidized lipids; SASP; DAMP;
Keywords: mTORC1; mammalian target of rapamycin complex 1; SADF; senescence-associated DNA damage foci; SAHF; senescence-associated heterochromatic foci; SASP; senescence-associated secretory phenotype; SA-β-GAL; senescence-associated β-galactosidase; Cellular se
Keywords: senescence; tumor immune microenvironment; SASP
Keywords: COPD; chronic obstructive pulmonary disease; RS; replicative senescence; SIPS; stress induced premature senescence; OIS; oncogene induced senescence; SASP; senescence associated secretory phenotype; TNF-a; tumor necrosis factor-a; TNFR1; TNFa receptor 1;
Keywords: SASP; senescence-associated secretory phenotype; DDR; DNA-damage response; OIS; oncogene-induced senescence; ROS; reactive oxygen species; HMGB1; nuclear protein high mobility group box 1; SAHF; senescence-associated heterochromatin foci; SMS; senescence-
Keywords: SA-βgal; senescence-associated β-galactosidase; SASP; senescence-associated secretory phenotype; FDA; Food and Drug Administration; GHRKO; growth hormone receptor knockout; ATTAC; apoptosis through targeted activation of caspase 8; BubR1; budding uninhi
Keywords: COX-2; cyclo-oxygenase-2; 5-FU; 5-fluorouracil; HE; hematoxylin and eosin; HQT; Huangqin Tang; HQTL; low dose of HQT extract with 1Â g/kg; HQTM; medium dose of HQT extract with 2Â g/kg; HQTH; high dose of HQT extract with 4Â g/kg; IBD; inflammatory bowel
Keywords: BMP; bone morphogenetic protein; EMT; epithelial-mesenchymal transition; MET; mesenchymal-epithelial transition; SA-β-gal; senescence β-galactosidase; SASP; senescence-associated secretory phenotype; TGF-β; transforming growth factor β;
Keywords: Gy; gray; Ab; antibody; TGF-β; transforming growth factor-β; TNF; tumor necrosis factor; SASP; senescence-associated secretory phenotype; MCP-1; monocyte chemoattractant protein-1; MHC; major histocompatibility complex; DAMP; damage-associated molecular
Keywords: Chip-qPCR; chromatin immunoprecipitation quantitative polymerase chain reaction; COL1A1; collagen alpha-1(I) chain; DDR; DNA damage response; DEM; diethylmaleate; EJC; exon junction complex; ETP; etoposide; H3K4me3; trimethylation of histone H3 at Lys4; H
Keywords: ARF; alternative reading frame; αSMA; alpha smooth muscle actin; CDK; cyclin-dependent kinase; DDR; DNA damage response; ECM; extracellular matrix; EMT; epithelial mesenchymal transition; FGF; fibroblast growth factor; HDAC; histone deacetylase; HIC1; hy
Keywords: ATM; ataxia telangiectasia mutated; ATP; adenosine triphosphate; Chk2; checkpoint kinase 2; DNA-PKcs; DNA-dependent protein kinase catalytic subunit; DUSP; dual-specificity phosphatase; HIV; human immunodeficiency virus; IL; interleukin; MCP1; monocyte ch
Keywords: Cancer; Aging; Elderly; Telomeres; Inflammaging; Immunosenescence; IL-6; MCP-1; RANTES; IGF-1; SASP; Chitinase; CRAMP; Aging genes
Keywords: Senolytic; an agent that targets senescent cells; ADME; absorption, distribution, metabolism, and excretion of a drug; SASP; senescence-associated secretory phenotype; mTOR; mammalian target of rapamycin; JAK; Janus-activated kinase; GLP; good laboratory
Keywords: ASA; aminosalicylates; CD; Crohn's disease; DIN; Drug Identification Number; GPRD; General Practice Research Database; IBD; inflammatory bowel disease; MP; mercaptopurine; ODB; Ontario Drug Database; SASP; sulfasalazine; TR; Thompson Reuters; UC; ulcerati
Keywords: Endothelial cells; Immunosenescence; SASP; Ageing
Kuijieling regulates the differentiation of Treg and Th17 cells to ameliorate experimental colitis in rats
Keywords: UC; ulcerative colitis; KJL; Kuijieling; Tregcells; regulatory T cells; Th17cells; T helper 17 cells; Foxp3; forkhead box P3; RORγt; retinoic acid-related orphan receptor γt; TGF-β1; transforming growth factor-β1; IL; interleukin; STAT; signal transdu
Role of extracellular vesicles in rheumatoid arthritis
Keywords: FLS; fibroblast-like synoviocyte; APC; antigen presenting cell; EV; extracellular vesicle; MMP; matrix metalloproteinase; VEGF; vascular endothelial growth factor; Id1; inhibitor of DNA binding 1; CD13; aminopeptidase N; MCP; monocyte chemoattractant prot
Ginsenoside F1 suppresses astrocytic senescence-associated secretory phenotype
Keywords: Astrocytic senescent; Ginsenoside F1; p38MAPK; NF-κB; SASP; Glioblastoma;
DNA damage, metabolism and aging in pro-inflammatory T cells
Keywords: EC; endothelial cell; ROS; reactive oxygen species; ATP; adenosine 5â²-triphosphate; ER; endoplasmic reticulum; mtDNA; mitochondrial DNA; ETC; electron transport chain; mROS; mitochondrial ROS; NADPH; nicotinamide adenine dinucleotide phosphate; TNF-α;
Selenium unmasks protective iron armor: A possible defense against cutaneous inflammation and cancer
Keywords: GPX4; Glutathione Peroxidase 4; System XC; Cystine/Glutamate Antiporter-System XC; TNFα; Tumor necrosis factor alpha; VEGF; Vascular endothelial growth factor; S1P; Sphingosine-1 phosphate; IL-22; Interleukin-22; Trx1; Thioredoxin; Txnrd1; Thioredoxin re
Cancer secretome and inflammation: The bright and the dark sides of NF-κB
Keywords: Secretome; Inflammation; Senescence; SASP; NF-κB; Immunity;
SIPS as a model to study age-related changes in proteolysis and aggregate formation
Keywords: AGEs; advanced glycation endproducts; ALP; autophagy-lysosomal pathway; ATM; ataxia teleangiectasia mutated; BrdU; bromodeoxyuridine; DDR; DNA damage response; DOX; doxorubicin; HDFs; Human diploid fibroblasts; H2O2; hydrogen peroxide; ICAM; intercellular
Divergent mechanisms of metabolic dysfunction drive fibroblast and T-cell senescence
Keywords: Ageing; T-cell; Fibroblast; Senescence; Metabolism; SASP;
Blockade of vascular endothelial growth factor receptor-1 (Flt-1), reveals a novel analgesic for osteoarthritis-induced joint pain
Keywords: OA; osteoarthritis; PMM; partial medial meniscectomy; h; hour; PWT; paw withdrawal threshold; PTT; paw thermal threshold; DRG; dorsal root ganglion; IT; intrathecal; IA; intraarticular; RT-PCR; Real-time polymerase chain reaction; P; probability; SEM; sta
Tris (2-chloroethyl) phosphate induces senescence-like phenotype of hepatocytes via the p21Waf1/Cip1-Rb pathway in a p53-independent manner
Keywords: DMSO; dimethyl sulfoxide; FBS; fetal bovine serum; IL; 6 interleukin-6; MAPK; mitogen-activated protein kinase; MTT; 3-(4 5-dimethyithiazol-2-yl)-2,5-diphenyl-tetrazolium bromide; Rb; retinoblastoma; SA-β-Gal; senescence-associated β-galactosidase; SASP