Understanding the pathophysiology of severe asthma to generate new therapeutic opportunities
Keywords: آسم شدید; Severe asthma; airway remodeling; tumor necrosis factor; etanercept; anti-IgE; omalizumab; a disintegrin and metalloprotease 33; airway responsiveness; new treatmentsADAM, A disintegrin and metalloprotease; APP, Amyloid precursor peptide; BAL, Bronchoalve