دانلود مقالات ISI درباره SHH، جغد صوتی + ترجمه فارسی

تنظیم اپی ژنتیکی میوگنز جنین و باززایی عضله بزرگسالان با تغییر متیلات هیستون

The epigenetic regulation of embryonic myogenesis and adult muscle regeneration by histone methylation modification

Keywords: SHH، جغد صوتی; SCs, satellite cells; MRFs, myogenic regulatory factors; bHLH, basic helix-loop-helix; MEF2, myocyte enhancer factor 2; Shh, sonic hedgehog; BMP4, bone morphogenic protein 4; p38 MAPK, p38 mitogen-activated protein kinase; H3K4, methylation of histone H3

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

سلول های ستون فقرات پانکراس: یک بازیکن پویا از ارتباط بین سلول در سرطان پانکراس؟

Pancreatic stellate cells: A dynamic player of the intercellular communication in pancreatic cancer

Keywords: SHH، جغد صوتی; CSC, cancer stem cell; ECM, extracellular matrix; EMT, epithelial-mesenchymal transition; IL, interleukin; MDSC, myeloid-derived suppressor cells; miRNA, microRNA; PSC, pancreatic stellate cells; Shh, Sonic hedgehog; SMA, smooth muscle actin; VEGF, vascul

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

یک پروتکل تمایز سریع و ساده برای مطالعه فعالیت پروتئورژنتیک فاکتورهای محلول در فضاهای عصبی

A fast and simple differentiation protocol to study the pro-neurogenic activity of soluble factors in neurospheres

Keywords: SHH، جغد صوتی; Neurosphere assay; EGF receptor; Erk1/2; Akt; ShhaNS, adult; SVZ, derived neurosphere(s); EGF, epidermal growth factor; ERK, extracellular signal-regulated kinases; OB, olfactory bulb; RMS, rostral migratory stream; Shh, Sonic Hedgehog; SVZ, subventricula

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

مکانیزم های چندگانه می توانند باعث افزایش تکثیر سلول های ساقه عضلانی / پرونوتیوئیک ناشی از تائورین از ناحیه ساب مغلوب موش بالغ

Multiple mechanisms mediate the taurine-induced proliferation of neural stem/progenitor cells from the subventricular zone of the adult mouse

Keywords: SHH، جغد صوتی; NPCs, neural precursor cells; SVZ, subventricular zone; EGF, epidermal growth factor; FGF2, fibroblast growth factor 2; BrdU, 5-bromo-2′-deoxyuridine; Shh, sonic hedgehog; Wnt, wingless integrated; CFSE, carboxyfluorescein diacetate succinimidyl ester; Δψ

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

پاتوژنز استئاتوهپاتیت غیرالکلی

Pathogenesis of Nonalcoholic Steatohepatitis

Keywords: SHH، جغد صوتی; Nonalcoholic Fatty Liver Disease; Lipotoxicity; Wound-Healing Response; MisrepairNAFL, nonalcoholic fatty liver; NAFLD, nonalcoholic fatty liver disease; NASH, nonalcoholic steatohepatitis; SHH, sonic hedgehog; SMO, smoothened, frizzled class receptor; TN

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Multiomics approach showing genome-wide copy number alterations and differential gene expression in different types of North-Indian pediatric brain tumors

Keywords: SHH، جغد صوتی; MB, Medulloblastoma; SHH, Sonic Hedgehog; MAGIC, Medulloblastoma advanced. Genomics International Consortium stratifying and targeting pediatric medulloblastoma through genomics; HTA, Human Transcriptome Array 2.0; CNVs, Copy number variations; MIP, Molec

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Shh mediates PDGF-induced contractile-to-synthetic phenotypic modulation in vascular smooth muscle cells through regulation of KLF4

Keywords: SHH، جغد صوتی; PDGF, platelet-derived growth factor; VSMCs, vascular smooth muscle cells; Shh, sonic hedgehog; Gli2, Gli family zinc finger 2; Tpm 4, tropomyosin 4; KLF4, Kru¨ppel-like factor 4; SRF, serum response factor; PDGF-BB, platelet-derived growth factor BB; PDG

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Melittin induces PTCH1 expression by down-regulating MeCP2 in human hepatocellular carcinoma SMMC-7721 cells

Keywords: SHH، جغد صوتی; HCC, Hepatocellular carcinoma; MBDs, Methyl-CpG-binding proteins; MeCP2, Methyl-CpG binding protein 2; Shh, Sonic hedgehog; HDAC2, Histone deacetylase 2; CDK4, Cyclin-dependent kinase 4; 5-azadC, 5-Aza-2′-deoxycytidine; PTCH-1, Patched-1; SMO, Smoothened;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Sonic Hedgehog signaling regulates vascular differentiation and function in human CD34 positive cells: Vasculogenic CD34+ cells with Sonic Hedgehog

Keywords: SHH، جغد صوتی; SHh, Sonic Hedgehog; EPC, endothelial progenitor cell; EPC-CFA, endothelial progenitor cell-colony forming assay; EC, endothelial cell; VSMC, vascular smooth muscle cell; PTCH, patched receptor; SMO, smoothened; HUVEC, human umbilical vein endothelial cel

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

DNA Copy Number Variations in Patients with Persistent Cloaca

Keywords: SHH، جغد صوتی; urinary bladder; genitalia; female; cloaca; DNA copy number variations; genomeaCGH, array comparative genomic hybridization; CNV, copy number variation; HHAT, hedgehog acyltransferase; SHH, sonic hedgehog; UPIIIA, uroplakin IIIA

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

Heterozygous mutations in the FGF8, SHH and nodal/transforming growth factor beta pathways do not confer increased dopaminergic neuron vulnerability—A zebrafish study

Keywords: SHH، جغد صوتی; fgf8, fibroblast growth factor 8; shh, sonic hedgehog; PD, Parkinson's disease; MPP+, 1-Methyl-4-phenyl-pyridinium; TGF-β, transforming growth factor beta; 6-OHDA, 6-hydroxydopamine; WISH, whole-mount in situ hybridization; TH, tyrosine hydroxylase; FWD,

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

Smoothened controls cyclinD2 expression and regulates the generation of intermediate progenitors in the developing cortex

Keywords: SHH، جغد صوتی; Shh, Sonic hedgehog; Smo, Smoothened; IPCs, intermediate progenitor cells; GFAP, glial fibrillary acidic protein; TH, tyrosine hydroxylaseIntermediate progenitor cell; Astrocyte; Cell cycle; Neocortex; Sonic hedgehog

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Association of HHIP polymorphisms with COPD and COPD-related phenotypes in a Chinese Han population

Keywords: SHH، جغد صوتی; HHIP, hedgehog interacting protein; COPD, chronic obstructive pulmonary disease; GWAS, genome-wide association studies; SHH, sonic hedgehog; SNPs, single nucleotide polymorphisms; BMI, body mass index; FEV1, forced expiratory volume in 1 s; FVC, forced vi

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

PTCH1 mutation and local aggressiveness of odontogenic keratocystic tumors in children: is there a relationship?

Keywords: SHH، جغد صوتی; KCOT, keratocystic odontogenic keratocystic tumor; NBCCS, nevoid basal cell carcinoma syndrome; PCR, polymerase chain reaction; PTCH1, protein patched homolog 1; SHH, sonic hedgehog; IL, interleukin; RANKL, receptor activator of nuclear factor κB ligandJa

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

The effect of purmorphamine and sirolimus on osteogenic differentiation of human bone marrow-derived mesenchymal stem cells

Keywords: SHH، جغد صوتی; Small molecules; Human mesenchymal stem cells; Purmorphamine; Sirolimus; Osteogenic differentiationhBM-MSCs, Human bone marrow-derived mesenchymal stem cells; ALP, Alkaline phosphatase; Shh, Sonic hedgehog

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Elevated adiponectin expression promotes adipose tissue vascularity under conditions of diet-induced obesity

Keywords: SHH، جغد صوتی; Apn-KO, adiponectin knockout mouse; Apn-TG, adiponectin transgenic/overexpressing mouse; CLS, crown-like structure; HFHS, high fat/high sucrose diet; IL-6, interleukin 6; Shh, Sonic Hedgehog; TNFα, tumor necrosis factor alpha; VEGF-A, vascular endothelial

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Epigenetic regulation of neural stem cell fate during corticogenesis

Keywords: SHH، جغد صوتی; Neural stem cells; Transcription factor; Epigenetics; Corticogenesis; Projection neurons; Cortical layerGABA, gamma-aminobutyric acid; FGF, fibroblast growth factor; BMP, bone morphogenetic protein; WNT, wingless int; SHH, sonic hedgehog; RA, retinoic aci

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

In vitro reprogramming of rat bone marrow-derived mesenchymal stem cells into insulin-producing cells by genetically manipulating negative and positive regulators

Keywords: SHH، جغد صوتی; bmMSCs, bone marrow-derived mesenchymal stem cells; Rest/Nrsf, repressor element-1 silencing transcription factor/neuronal restrictive silencing factor; Shh, sonic hedgehog; Pdx1, pancreas and duodenal transcription factor 1; GFP, green fluorescent protei

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Transgenic enrichment of mouse embryonic stem cell-derived progenitor motor neurons

Keywords: SHH، جغد صوتی; pMNs, progenitor motor neurons; PAC, puromycin N-acetyl transferase (PAC); NF, neurofilament; ChAT, choline acetyl transferase, MN, motoneuron; RA, retinoic acid; Shh, sonic hedgehog; Isl1, Islet1; GRE, gene regulatory elements; O4, oligodendrocyte marker

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Prenatal exposure to di-n-butyl phthalate induces anorectal malformations in male rat offspring

Keywords: SHH، جغد صوتی; DBP, di-n-butyl phthalate; ARMs, anorectal malformations; GD, gestation day; PND, postnatal day; BW, bodyweight; AGD, anogenital distance; T, testosterone; AR, androgen receptor; Shh, sonic hedgehog; Bmp4, bone morphogenetic protein; PAEs, phthalic acid e

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

p63 in tooth development

Keywords: SHH، جغد صوتی; BMP, bone morphogenetic protein; FGF, fibroblast growth factor; FGFR, fibroblast growth factor receptor; SHH, sonic hedgehog; TNF, tumor necrosis factor; Apc, adenomatous polyposis coli; SAM, sterile alpha motif; TID, transactivation inhibitory domain; AB

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Nkx3.2-induced suppression of Runx2 is a crucial mediator of hypoxia-dependent maintenance of chondrocyte phenotypes

Keywords: SHH، جغد صوتی; Shh, Sonic hedgehog; Runx2, Runt related transcription factor 2; BMP, bone morphogenic protein; GAG, glycosaminoglycan; RNAi, RNA interference; siRNA, small interference RNA; Hif-1, hypoxia-inducible factor 1; SMMD, spondylo-megaepiphysial-metaphysial dys

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Identification of Hedgehog signaling inhibitors with relevant human exposure by small molecule screening

Keywords: SHH، جغد صوتی; Hh, Hedgehog; HPE, holoprosencephaly; CLP, cleft lip and palate; Ptc1, Patched; Smo, Smoothened; Shh, Sonic Hedgehog; MEF, mouse embryonic fibroblastsHedgehog signaling; Cyclopamine; Small molecule screening; Birth defects

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Activation of Erk by sonic hedgehog independent of canonical hedgehog signalling

Keywords: SHH، جغد صوتی; Shh, sonic hedgehog; Smo, smoothened; Ptch1, Patched-1; Hh, Hedgehog; HMEC, human mammary epithelial cells; FTase II, H-Cys-4-Abz-Met-OH; GST, glutathione S transferase; GFP, green fluorescent protein; MEK, mitogen-activated protein kinase kinase; Erk, ex

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Molecular and toxicologic research in newborn hypospadiac male rats following in utero exposure to di-n-butyl phthalate (DBP)

Keywords: SHH، جغد صوتی; DBP, di-n-butyl phthalate; bw, body weight; GD, gestation day; PND, postnatal day; GT, genital tubercle; Shh, sonic hedgehog; Ptch1, Ptched 1; BMP4, bone morphogenetic protein 4; BMP7, bone morphogenetic protein 7; Fgf8, fibroblast growth factor-8; Fgf10,

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Vitronectin promotes oligodendrocyte differentiation during neurogenesis of human embryonic stem cells

Keywords: SHH، جغد صوتی; hESCs, human embryonic stem cells; VN, vitronectin; Shh, sonic hedgehog; hEBs, human embryoid bodies; RA, retinoic acid; GRM, glial restriction medium; bFGF, fibroblast growth factor; PDGF, platelet-derived growth factor; IGF-I, insulin-like growth factor

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Estradiol promotes proliferation of dopaminergic precursors resulting in a higher proportion of dopamine neurons derived from mouse embryonic stem cells

Keywords: SHH، جغد صوتی; DA, dopamine; E2, estradiol; ER, estrogen receptor; ESC, embryonic stem cells; FGF, Fibroblast growth factor; GAPDH, Glyceraldehyde phosphate dehydrogenase; PD, Parkinson's disease; SHH, Sonic hedgehog; TH, tyrosine hydroxylaseDopamine neurons; Embryonic

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Functional studies of membrane-bound and purified human Hedgehog receptor Patched expressed in yeast

Keywords: SHH، جغد صوتی; Hh, Hedgehog; Shh, Sonic Hedgehog; hSmo, human Smoothened; hPtc, human Patched; AOX1, alcohol oxidase 1; PMSF, phenylmethylsulfonyl fluoride; CBD, calmodulin binding domain; HA, hemagglutinin A; PCR, polymerase chain reaction; SDS-PAGE, sodium dodecyl sul

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Paracrine Hedgehog Signaling in Stomach and Intestine: New Roles for Hedgehog in Gastrointestinal Patterning

Keywords: SHH، جغد صوتی; Dhh, Desert Hedgehog; E, embryonic day; Hh, Hedgehog; Ihh, Indian Hedgehog; ME, muscularis externa; MM, muscularis mucosa; Ptch, Patched; Shh, Sonic Hedgehog; SM, smooth muscle; SMA, smooth muscle actin; Smo, Smoothened; VACTERL, vertebral, anal, cardiac,

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Overexpression of hedgehog pathway molecules and FOXM1 in non-small cell lung carcinomas

Keywords: SHH، جغد صوتی; HH, hedgehog; NSCLC, non-small cell lung cancer; FOXM1, Forkhead Box M1; SHH, sonic hedgehog; PTCH1, patched1; SMO, Smoothened; SCLC, small cell lung cancer; SuFu, suppressor of fusedGLI; FOXM1; Hedgehog; NSCLC; PTCH1; SHH; SMO

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Combined Targeted Treatment to Eliminate Tumorigenic Cancer Stem Cells in Human Pancreatic Cancer

Keywords: SHH، جغد صوتی; CRG, cyclopamine, rapamycin, and gemcitabine; CSC, cancer stem cell; mTOR, mammalian target of rapamycin; Shh, sonic hedgehog

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2009 سفارش ترجمه

Molecular mechanisms of vertebrate retina development: Implications for ganglion cell and photoreceptor patterning

Keywords: SHH، جغد صوتی; A, anterior; P, posterior; D, dorsal; V, ventral; RGC, retinal ganglion cell; BMP, bone morphogenic protein; FGF, fibroblast growth factor; Shh, sonic hedgehog; RA, retinoic acid; TGFβ, transforming growth factor β; RALDH, retinaldehyde dehydrogenase; SOH

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2008 سفارش ترجمه

Embryonic salivary gland dysmorphogenesis in Twisted gastrulation deficient mice

Keywords: SHH، جغد صوتی; BMP, bone morphogenetic protein; BSA, bovine serum albumin; FGF8, fibroblast growth factor 8; Pitx1, paired-like homeodomain transcription factor 1; Shh, sonic hedgehog; SMG, submandibular salivary gland; Tsg, twisted gastrulation; Twsg1, twisted gastrula

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

Soluble factors from neuronal cultures induce a specific proliferation and resistance to apoptosis of cognate mouse skeletal muscle precursor cells

Keywords: SHH، جغد صوتی; mpc, muscle precursor cells; BMP, bone morphogenetic protein; BrdU, bromodeoxyuridine; Shh, sonic hedgehog; STS, staurosporineMuscle precursor cells; Expansion; Survival; Neuron

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه

Activation of the hedgehog pathway in a subset of lung cancers

Keywords: SHH، جغد صوتی; Hedgehog; Lung cancer; Gli1; Su(Fu); PTCH1PTC, patched; PTCH1, human patched gene 1; NSCLC, non-small cell lung cancer; shh, sonic hedgehog; BCC, basal cell carcinoma; Su(Fu), suppressor of fused

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

Myocyte-specific enhancer factor 2A is essential for zebrafish posterior somite development

Keywords: SHH، جغد صوتی; MEF2A, myocyte-specific enhancer factor 2A; hpf, hours post fertilization; MO, morpholino; TUNEL, terminal deoxynucleotide transferase-mediated dUTP nick-end labeling; shh, sonic Hedgehog; ehh, echidna Hedgehog; twhh, tiggywinkle HedgehogMEF2A; Somite; De

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Transcriptional control of Shh/Ptc1 signaling in embryonic development

Keywords: SHH، جغد صوتی; Shh, Sonic Hedgehog; Ptc, patched; Smo, smoothened; Gli, glioblastoma; TGF-β2, transforming growth factor β2; Tbx, T box family member protein; Msx, muscle segment homologue; Lmx, homeodomain protein; Smad, mothers against DPP homologue; TF, transcription

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

Stomach Development Is Dependent on Fibroblast Growth Factor 10/Fibroblast Growth Factor Receptor 2b–Mediated Signaling

Keywords: SHH، جغد صوتی; BSA, bovine serum albumin; E, embryonic day; Fgf, fibroblast growth factor; Fgfr, fibroblast growth factor receptor; Ihh, Indian hedgehog; Shh, Sonic hedgehog; wt, wild-type

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2006 سفارش ترجمه

PPARβ/δ Regulates Paneth Cell Differentiation Via Controlling the Hedgehog Signaling Pathway

Keywords: SHH، جغد صوتی; CFU, colony-forming unit; Hip, Hedgehog interacting protein; Ihh, Indian hedgehog; P, postpartum; PPAR, peroxisome proliferator–activated receptor; RPA, RNase Protection Assay; Shh, Sonic hedgehog

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2006 سفارش ترجمه

Hedgehog Signal Activation in Gastric Pit Cell and in Diffuse-Type Gastric Cancer

Keywords: SHH، جغد صوتی; DHH, Desert hedgehog; GLI, glioma-associated oncogene homolog; Hh, Hedgehog; IHH, Indian hedgehog; KRT8, cytokeratin 8; PCNA, proliferating cell nuclear antigen; PTCH, patched; RT-PCR, reverse-transcription polymerase chain reaction; SHH, Sonic hedgehog;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2006 سفارش ترجمه

Sonic hedgehog signaling in basal cell carcinomas

Keywords: SHH، جغد صوتی; Basal cell carcinoma; Ultraviolet; Mutation; Sonic hedgehog; Patched; Smoothened; BCC, basal cell carcinoma; SHH, sonic hedgehog; PTCH, patched; SMO, smoothened; HIP, hedgehog interacting protein; NBCC, nevoid basal cell carcinoma; XP, xeroderma pigmentos

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه