دانلود مقالات ISI درباره Sirt3 + ترجمه فارسی

Exercise increases mitochondrial complex I activity and DRP1 expression in the brains of aged mice

Keywords: PGC-1α; peroxisome proliferator-activated receptor gamma co-activator 1α; TFAM; mitochondrial transcription factor A; BDNF; brain-derived neurotrophic factor; ETC; electron transport chain; OC; old control group; OT; old trained group; YC; young control

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2017 سفارش ترجمه

Melatonin-mediated upregulation of Sirt3 attenuates sodium fluoride-induced hepatotoxicity by activating the MT1-PI3K/AKT-PGC-1α signaling pathway

Keywords: NaF; Sodium; ROS; Reactive oxygen species; O2•−; superoxide; GSH; Glutathione; MDA; Malondialdehyde; Bax; Bcl2-associated X protein; Bcl-2; B-cell CLL/lymphoma 2; GAPDH; Glyceraldehyde-3-Phosphate Dehydrogenase; COXIV; Cytochrome C Oxidase Subunit IV;

دانلود رایگان متن کامل مقاله ISI 65 صفحه سال انتشار : 2017 سفارش ترجمه

SIRT3 in cardiovascular diseases: Emerging roles and therapeutic implications

Keywords: SIRT3; Cardiovascular disease; Oxidative stress; Ischemia-reperfusion injury; Mitochondrial metabolism; Cellular death;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Mitochondrial Sirt3 supports cell proliferation by regulating glutamine-dependent oxidation in renal cell carcinoma

Keywords: Renal cell carcinoma; Sirt3; Mitochondrial oxidation; Glutamate dehydrogenase;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Resveratrol attenuates oxidative stress in mitochondrial Complex I deficiency: Involvement of SIRT3

Keywords: Complex I deficiency; Oxidative stress; Mitochondrial diseases; Pharmacological therapy; Resveratrol; SOD2; SIRT3;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Ablation of SIRT3 causes coronary microvascular dysfunction and impairs cardiac recovery post myocardial ischemia

Keywords: SIRT3; Pericyte; CFR; Myocardial ischemia;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Fusaric acid induces mitochondrial stress in human hepatocellular carcinoma (HepG2) cells

Keywords: Fusaric acid; Sirt3; Nrf2; Lon protease; PGC-1α; pCREB; HSP70; Caspase 3/7

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Altered cellular redox status, sirtuin abundance and clock gene expression in a mouse model of developmentally primed NASH

Keywords: NAFLD; non-alcoholic fatty liver disease; NASH; non-alcoholic steatohepatitis; HF; high fat; C; control; sirt1; sirtuin 1; sirt3; sirtuin 3; Clock; circadian locomotor output cycles kaput; Per2; Bmal1 (also called Arntl1), period 2; Cry2; cryptochrome 2;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Garlic activates SIRT-3 to prevent cardiac oxidative stress and mitochondrial dysfunction in diabetes

Keywords: SIRT3; MnSOD; Garlic; Acetylation; Mitochondria; Diabetic cardiomyopathy; Sirtuins;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Activation of SIRT3 attenuates triptolide-induced toxicity through closing mitochondrial permeability transition pore in cardiomyocytes

Keywords: Triptolide; SIRT3; Mitochondrial permeability transition pore; Cardioprotection;

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2016 سفارش ترجمه

A SIRT3/AMPK/autophagy network orchestrates the protective effects of trans-resveratrol in stressed peritoneal macrophages and RAW 264.7 macrophages

Keywords: AAPH; 2,2′-azobis (2-amidinopropane) dihydrochloride; AMPK; AMP-activated protein kinase; ComC; compound C; Edar; edaravone; 3-MA; 3-methyladenine; MMP; mitochondrial membrane potential; Rapa; rapamycin; Resv; trans-resveratrol; VitC; vitamin C; Autopha

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2016 سفارش ترجمه

Novel thiourea-based sirtuin inhibitory warheads

Keywords: β-NAD+; β-nicotinamide adenine dinucleotide; 2′-O-AADPR; 2′-O-acyl-ADP-ribose; IC50; the inhibitor concentration at which an enzymatic reaction velocity is reduced by 50%; SPPS; solid phase peptide synthesis; RP-HPLC; reversed-phase high pressure li

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Sirt3 binds to and deacetylates mitochondrial pyruvate carrier 1 to enhance its activity

Keywords: MPC1; Sirt3; Acetylation; Cell growth;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Skeletal muscle Sirt3 expression and mitochondrial respiration are regulated by a prenatal low-protein diet

Keywords: Maternal low-protein diet; Skeletal muscle respiration; Mitochondria; SIRT3; SDH

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Characterization of novel mechanisms for steatosis from global protein hyperacetylation in ethanol-induced mouse hepatocytes

Keywords: Lysine acetylation; Ethanol; Hyperacetylation; SIRT3; AML-12 cell; Steatosis;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

SIRT3 regulates progression and development of diseases of aging

Keywords: mitochondria; sirtuins; SIRT3; aging; disease

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

{2-[1-(3-Methoxycarbonylmethyl-1H-indol-2-yl)-1-methyl-ethyl]-1H-indol-3-yl}-acetic acid methyl ester (MIAM) inhibited human hepatocellular carcinoma growth through upregulation of Sirtuin-3 (SIRT3)

Keywords: Indole compound; MIAM; Hepatocellular carcinoma; HepG2 xenografts; Apoptosis; SIRT3; Hypoxic environment

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Cyclophilin D and myocardial ischemia-reperfusion injury: A fresh perspective

Keywords: ANT; adenine nucleotide translocator; ATP; adenosine triphosphate; ATP5G; ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C1 (subunit 9); BAK; BCL2-antagonist/killer; BAX; BCL2-associated X protein; BCL-2; B cell lymphoma protein 2; C1QBP

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Mechanisms of cell death pathway activation following drug-induced inhibition of mitochondrial complex I

Keywords: Sirt3; Efavirenz; Complex I inhibition; Mitochondria; Peroxynitrite; Drug-induced liver injury (DILI)CBA, coumarin-7-boronic acid; CYP, cytochrome P450; CypD, cyclophilin D; ETC, electron transport chain; Fe-TCP, Fe(III) tetrakis(4-carboxyphenyl) porphyri

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Sirtuin 3 regulates Foxo3a-mediated antioxidant pathway in microglia

Keywords: AD; Alzheimer's disease; Cat; catalase; CNS; central nervous system; CC; corpus callosum; Foxo3a; forkhead box O 3a; LPS; lipopolysaccharide; mnSod; manganese superoxide dismutase; PD; Parkinson's disease; ROS; reactive oxygen species; Sirt 3; sirtuin

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2015 سفارش ترجمه

Sirtuin 3 interacts with Lon protease and regulates its acetylation status

Keywords: Lon; Lon protease; CDDO; 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid; PMSF; phenylmethanesulfonyl fluoride; SIRT3; sirtuin 3; AADPR; 2′-O-acetyl-ADP ribose; DMEM; Dulbecco's modified Eagle's medium; NAD; nicotinammide adenina dinucleotide; EGTA; ethyl

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Decreased mitochondrial SIRT3 expression is a potential molecular biomarker associated with poor outcome in breast cancer

Keywords: Sirt3; Breast cancer; Clinical outcomes; Sirtuins; Metabolism; Mitochondria;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Pituitary adenylate cyclase-activating polypeptide protects against β-amyloid toxicity

Keywords: Alzheimer's disease; PACAP; SIRT3; Mitochondrial respiration;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Sirt3 controls chromosome alignment by regulating spindle dynamics during mitosis

Keywords: Sirt3; Spindle assembly checkpoint; Chromosome alignment; Spindle dynamics;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Small-molecule inhibitors at the PSD-95/nNOS interface attenuate MPP+-induced neuronal injury through Sirt3 mediated inhibition of mitochondrial dysfunction

Keywords: Parkinson's disease; PSD-95; nNOS; Mitochondrial dysfunction; Sirt3

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

SIRT3 deacetylates and increases pyruvate dehydrogenase activity in cancer cells

Keywords: Pyruvate dehydrogenase; SIRT3; PDHA1; Acetylation; Carcinogenesis; Warburg; Free radicals;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Sirtuins: guardians of mammalian healthspan

Keywords: aging; longevity; age-associated disease; NAD+; mitochondria; SIRT1; SIRT3; SIRT6

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2014 سفارش ترجمه

SIRT3 protects cardiomyocytes from oxidative stress-mediated cell death by activating NF-κB

Keywords: SIRT3; NF-κB; Cardiomyocytes; Oxidative stress; Apoptosis;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Identification of novel SIRT3 inhibitor scaffolds by virtual screening

Keywords: SIRT3; Inhibitor scaffold; Virtual screening; Shape matching; Docking;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Research ArticleAdipose tissue and liver expression of SIRT1, 3, and 6 increase after extensive weight loss in morbid obesity

Keywords: SIRT1; SIRT3; SIRT6; NAFLD; Insulin resistance; Metabolism;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Poly(ADP-ribose) polymerase inhibition prevents reactive oxygen species induced inhibition of aldehyde dehydrogenase2 activity

Keywords: poly(ADP-ribose) polymerase; ROS; Aldehyde dehydrogenase 2; SIRT3;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

The SIRT2 polymorphism rs10410544 and risk of Alzheimer's disease in two Caucasian case-control cohorts

Keywords: Sirtuin; Alzheimer's disease; SIRT2; SIRT3; APOE; Genetics;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Berberine reverts hepatic mitochondrial dysfunction in high-fat fed rats: A possible role for SirT3 activation

Keywords: ACC; acetyl-CoA carboxylase; AMPK; AMP-activated protein kinase; BBR; berberine-supplemented HFD group; Ctl; control low fat diet-fed group; FAME; fatty acid methyl ester; FCCP; carbonylcyanide-P-trifluoromethoxyphenylhydrazon; FFA; free fatty acids; HFD;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Regulation of mitochondrial FoF1ATPase activity by Sirt3-catalyzed deacetylation and its deficiency in human cells harboring 4977 bp deletion of mitochondrial DNA

Keywords: Energy metabolism; FoF1ATPase; Lysine acetylation; Mitochondrial disease; Oxidative stress; Sirt3;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

SIRT3 deacetylates FOXO3 to protect mitochondria against oxidative damage

Keywords: BAEC; bovine aortic endothelial cell; CR; caloric restriction; EC; endothelial cell; HUVEC; human umbilical vein endothelial cell; OCR; oxygen consumption rate; ROS; reactive oxygen species; SIRT3; FOXO3; Mitochondrial homeostasis; Mitochondrial biogenesi

دانلود رایگان متن کامل مقاله ISI 55 صفحه سال انتشار : 2013 سفارش ترجمه

Identification of Sirtuin 3, a mitochondrial protein deacetylase, as a new contributor to tamoxifen resistance in breast cancer cells

Keywords: Tamoxifen; Drug resistance; SIRT3; ERβ; Breast cancer

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

The role of SIRT3 in mitochondrial homeostasis and cardiac adaptation to hypertrophy and aging

Keywords: ALDH2; aldehyde dehydrogenase 2; AMPK; adenosine monophosphate kinase; CREB; cyclic AMP response element binding protein; GNAT; Gcn5-related N-acetyltransferase; HAT; histone acetyltransferase; HDAC; histone deacetylase; LCAD; long chain acetyl-CoA dehydr

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Exploring the electrostatic repulsion model in the role of Sirt3 in directing MnSOD acetylation status and enzymatic activity

Keywords: s: ROS; reactive oxygen species; CR; caloric restriction; MnSOD; manganese superoxide dismutase; CuZnSOD; copper zinc superoxide dismutase; EcSOD; extracellular superoxide dismutase; O2−; superoxide; H2O2; hydrogen peroxide; HO; hydroxyl radical; Sirt1â

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Sirt3 inhibits hepatocellular carcinoma cell growth through reducing Mdm2-mediated p53 degradation

Keywords: Sirt3; Hepatocellular carcinoma; p53; Mdm2

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

The role of sirtuins in modulating redox stressors

Keywords: SIRT1; SIRT3; Sirtuins; Mitochondria; Redox stress; Resveratrol; Metabolism; Free radicals

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Murine Sirt3 protein isoforms have variable half-lives

Keywords: NAD, nicotinamide adenine dinucleotide; HSP, heat shock protein; PCR, polymerase chain reactionSirtuin; Sirt3; Mitochondria; Proteasome; Protein half-life; HSP60

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

SIRT3 and cancer: Tumor promoter or suppressor?

Keywords: NAD+; Nicotinamide adenine dinucleotide; NAM; Nicotinamide; CR; Calorie Restriction; OSCC; Oral Squamous Cell Carcinoma; Sirtuin-3; SIRT3; Cancer; Tumor promoter; Tumor suppressor;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Mitochondrial sirtuins

Keywords: Mitochondria; Sirtuin; SIRT3; SIRT4; SIRT5; O-Acetyl-ADP-ribose; Acetylation

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

SIRT3 is regulated by nutrient excess and modulates hepatic susceptibility to lipotoxicity

Keywords: SIRT3; Lipotoxicity; Electron transfer chain; Reactive oxygen species; Palmitate; Free radicals

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Localization of mouse mitochondrial SIRT proteins: Shift of SIRT3 to nucleus by co-expression with SIRT5

Keywords: SIR2; silent information regulator 2; MTS; mitochondrial targeting signal; NLS; nuclear localization signal; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; PNS; post-nuclear supernatant; PHB; prohibitin; ER; estrogen receptor; SIRT3; SIRT4; SIRT5; Intra

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Characterization of a bidirectional promoter shared between two human genes related to aging: SIRT3 and PSMD13

Keywords: SIRT3; PSMD13; Bidirectional promoter; Human longevity

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

A novel VNTR enhancer within the SIRT3 gene, a human homologue of SIR2, is associated with survival at oldest ages

Keywords: SIRT3; Human longevity; VNTR enhancer;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه