Recent advances in hypoxia-inducible factor (HIF)-1 inhibitors
Keywords: مهار کننده های مولکولی کوچک; HIF-1; Angiogenesis; Anticancer drug; Small molecule inhibitors
مقالات ISI مهار کننده های مولکولی کوچک (ترجمه نشده)
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Strategies to inhibit viral protein nuclear import: HIV-1 as a target
Keywords: مهار کننده های مولکولی کوچک; HIV-1; Nuclear import; Pre-integration complex; Importins; Nuclear localization signal; Peptides; Small molecule inhibitors
Synthesis and biological evaluation of thio-benzodiazepines as novel small molecule inhibitors of the p53-MDM2 protein-protein interaction
Keywords: مهار کننده های مولکولی کوچک; p53-MDM2; Small molecule inhibitors; Thio-benzodiazepine; Antitumor activity;
Emerging importance of ALK in neuroblastoma
Keywords: مهار کننده های مولکولی کوچک; Neuroblastoma; ALK; Tyrosine kinase receptor; Targeted therapy; Crizotinib; Drug resistance; Point mutations; Small molecule inhibitors; Combination treatment
Identification of novel small molecule inhibitors of 4-diphosphocytidyl-2-C-methyl-d-erythritol (CDP-ME) kinase of Gram-negative bacteria
Keywords: مهار کننده های مولکولی کوچک; Isoprenoid biosynthesis; Gram-negative bacteria; 4-Diphosphocytidyl-2-C-methyl d-erythritol (CDP-ME); CDP-ME kinase; IspE; Yersinia pestis; Biodefense; Anti-terrorism; Small molecule inhibitors; Antibiotics; Antimicrobials
Targeted anti-cancer therapy in the elderly
Keywords: مهار کننده های مولکولی کوچک; Elderly; Targeted therapy; Small molecule inhibitors; Monoclonal antibodies
Identification of small molecule inhibitors of pyruvate kinase M2
Keywords: مهار کننده های مولکولی کوچک; PK, pyruvate kinase; FDG-PET, 18F-deoxyglucose positron emission tomography; FBP, fructose-1,6-bisphosphate; PEP, phosphoenolpyruvate; LDH, lactate dehydrogenasePyruvate kinase M2; Glycolysis; Cellular metabolism; Small molecule inhibitors; High-throughpu
MDM2 inhibitor MI-319 in combination with cisplatin is an effective treatment for pancreatic cancer independent of p53 function
Keywords: مهار کننده های مولکولی کوچک; MDM2 and p53; Small molecule inhibitors; Cisplatin; Apoptosis; Pancreatic cancer
Human AP endonuclease 1 (APE1): From mechanistic insights to druggable target in cancer
Keywords: مهار کننده های مولکولی کوچک; Cancer; Human AP endonuclease 1; APE1; Small molecule inhibitors
Development of quantitative and high-throughput assays of polyomavirus and papillomavirus DNA replication
Keywords: مهار کننده های مولکولی کوچک; Polyomavirus; Papillomavirus; DNA replication; Luciferase; SV40; HPV31; High-throughput; Cell-based assay; Small molecule inhibitors
Targeting DNA repair pathways: A novel approach to reduce cancer therapeutic resistance
Keywords: مهار کننده های مولکولی کوچک; DNA repair; Cancer therapy; Chemotherapy and radiotherapy resistance; Small molecule inhibitors
Role of APE1 in differentiated neuroblastoma SH-SY5Y cells in response to oxidative stress: Use of APE1 small molecule inhibitors to delineate APE1 functions
Keywords: مهار کننده های مولکولی کوچک; APE1; human apurinic (apyrimidinic) endonuclease/redox effector factor; WT-APE1; wild type APE1; C65-APE1; repair competent/redox deficient APE1; 177/226-APE1; repair deficient/redox competent APE1; MX; methoxyamine; BQP; 3-[5-(2,3-dimethoxy-6-methyl-1,4-
BRAF Signaling and Targeted Therapies in Melanoma
Keywords: مهار کننده های مولکولی کوچک; BRAF; Melanoma; MAPK signaling; Targeted therapies; Small molecule inhibitors;
HA14-1, a small molecule inhibitor of Bcl-2, bypasses chemoresistance in leukaemia cells
Keywords: مهار کننده های مولکولی کوچک; Bcl-2; Leukaemia; Small molecule inhibitors
Therapeutic options for hormone-refractory prostate cancer in 2007
Keywords: مهار کننده های مولکولی کوچک; Prostate cancer; Hormone refractory; Antisense oligonucleotides; Small molecule inhibitors; Targeted therapy
Design, synthesis, and biochemical evaluation of novel cruzain inhibitors with potential application in the treatment of Chagas’ disease
Keywords: مهار کننده های مولکولی کوچک; Chagas’ Disease; Cruzain inhibitors; Thiosemicarbazone functionality; Small molecule inhibitors; Molecular recognition; Drug discovery and development
Molecular targets and the treatment of myeloid leukemia
Keywords: مهار کننده های مولکولی کوچک; Targeted therapy; Chromosomal translocations; Apoptosis; Cell cycle; Small molecule inhibitors
Emergence and prevention of resistance against small molecule inhibitors
Keywords: مهار کننده های مولکولی کوچک; Cancer; Drug resistance; Small molecule inhibitors; CML; Gleevec; Imatinib; Somatic evolution; Mathematical models; Computational biology;