USF2 inhibits the transcriptional activity of Smurf1 and Smurf2 to promote breast cancer tumorigenesis
Keywords: اسمورف; USF2; Smurf; Transcriptional activity; Breast cancer;
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MicroRNA-181a and its target Smad 7 as potential biomarkers for tracking child acute lymphoblastic leukemia
Keywords: اسمورف; ALL; Acute lymphoblastic leukemia; AML; acute myeloid leukemia; CDKs; cyclin-dependent kinases; CLL; chronic lymphocytic leukemia; ELISA; enzyme linked immunosorbent assay; GSK3β; glycogen synthase kinase 3β; I-Smads; inhibitory Smads; qRT-PCR; quantita
Inflammation-driven colon neoplasmatogenesis in uPA-deficient mice is associated with an increased expression of Runx transcriptional regulators
Keywords: اسمورف; BMP; bone morphogenetic protein; Cldn1; Claudin1; Co-Smad; common-partner Smad; CRC; colorectal cancer; DSS; dextran sodium sulfate; ECM; extracellular matrix; EMT; epithelial to mesenchymal transition; GALT; gut-associated lymphoid tissue; Id; inhibitor
Regulation of the TGF-β pathway by deubiquitinases in cancer
Keywords: اسمورف; AMSH; Associated molecule with SH3 domain proteases; AMSH-LP; Associated molecule with SH3 domain-like proteases; ATXN3; ataxin-3; ATXN3L; ataxin 3-like; BMPs; bone morphogenetic proteins; BRCC36; BRCA1/BRCA2-containing complex subunit 36; CHIP; carboxy t
X-linked intellectual disability gene CUL4B targets Jab1/CSN5 for degradation and regulates bone morphogenetic protein signaling
Keywords: اسمورف; CUL4B; Cullin 4B; XLID; X-linked intellectual disability; Jab1; Jun activation domain-binding protein; CSN; the constitutive photomorphogenic-9 (COP9) signalosome; BMP; bone morphogenetic protein; CRLs; the cullin-RING ubiquitin ligases; DWD; DDB1-binding
Smurf-mediated differential proteolysis generates dynamic BMP signaling in germline stem cells during Drosophila testis development
Keywords: اسمورف; Drosophila; Spermatogenesis; Germline stem cells; BMP; Smurf; Proteolysis;
The TGF-β co-receptor, CD109, promotes internalization and degradation of TGF-β receptors
Keywords: اسمورف; TGF-β; transforming growth factor-β; Smurf; SMAD ubiquitination regulatory factor; GPI; glycosylphosphatidylinositol; MβCD; methyl-β-cyclodextrin; EEA-1; early endosome antigen-1; HA; hemagglutinin; TGF-β receptor; CD109; Internalization; Degradation
Pharmacological application of caffeine inhibits TGF-β-stimulated connective tissue growth factor expression in hepatocytes via PPARγ and SMAD2/3-dependent pathways
Keywords: اسمورف; 15-PGJ2; 15 deoxy prostaglandin J2; 8-Br-cAMP; 8-bromoadenosine-3â²,5â²-cyclic adenosine monophosphate; Alk4/Alk5; activin like receptor 4/5; cAMP; cyclic adenosine monophosphate; cAMP-PDE; cAMP-specific phosphodiesterase; CBP; CREB binding protein; co;