Keywords: پراکندگی جامد; Solid dispersions; D-optimal mixture experimental design; Surface adsorbent; Poorly soluble drugs; Polymorphism; Polymorphic conversion;
مقالات ISI پراکندگی جامد (ترجمه نشده)
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Keywords: پراکندگی جامد; Melt mixing; Solid dispersions; Soluplus; PVP; Poloxamer; Felodipine; Dissolution enhancement;
Keywords: پراکندگی جامد; nonpolar solvent; polar protic solvent; molecular interaction; solid dispersion; felodipine; spray drying; SDs; solid dispersions; ASDs; amorphous solid dispersions; DCM; dichloromethane; DSC; differential scanning calorimetry; EtOH; ethanol; FLDP; felodi
Keywords: پراکندگی جامد; sodium dodecyl sulfate; soluplus; amorphous solid dispersions; felodipine; hot melt extrusion; medium uptake; erosion; APIs; active pharmaceutical ingredients; SDs; solid dispersions; ASDs; amorphous solid dispersions; DSC; differential scanning calorimet
Keywords: پراکندگی جامد; Solid dispersions; Solid-liquid interfaces; Supersaturation; Mathematical model; Dissolution; Agglomeration; Ibuprofen; Polyvinylpyrrolidone;
Keywords: پراکندگی جامد; Self-micellizing; Fenofibrate; Dissolution/solubility; Hypolipidemic efficacy; Solid dispersions;
Keywords: پراکندگی جامد; Hot melt extrusion; Injection moulding; Surfactants; Solid dispersions; Physical stability; Polymorph;
Keywords: پراکندگی جامد; Solid dispersions; Ritonavir; Efavirenz; Nanoparticles; Precipitation; Solubility;
Keywords: پراکندگی جامد; Micro- and nanotechnologies in pain management; Cyclodextrin complexation; Solid dispersions; Vesicular systems; Micro and nanoparticles; Microemulsions
Keywords: پراکندگی جامد; Tadalafil; Soluplus®; High energy ball milling; Supercritical fluids; Glassy molecular alloys; Solid dispersions; Dissolution enhancement;
Keywords: پراکندگی جامد; Benznidazole; Solid dispersions; Sodium deoxycholate; Low-substituted hydroxypropylcellullose; Dissolution rate; Trypanocidal activity;
Keywords: پراکندگی جامد; Inorganic excipients; Solid dispersions; Continuous extrusion
Keywords: پراکندگی جامد; solid dispersions; tableting; compression; mixing; glass transition; spray drying; extrusion; calorimetry (DSC); X-ray diffrac-tometry; spectroscopy;
Keywords: پراکندگی جامد; Electrostatics; Solid dispersions; Triboelectrification; Indomethacin; d-Glucosamine HCl; PolymorphismGLU, glucosamine hydrochloride; DSC, differential scanning calorimetry; XRPD, X-ray powder diffraction; FTIR, Fourier transform infra-red; BCS, biopharma
Keywords: پراکندگی جامد; Solid dispersions; Carbamazepin-gluconolactone; Dissolution enhancement; Eutectic mixtures; Mechanistic solid state analysis
Keywords: پراکندگی جامد; Raman imaging; Drug delivery; Chemometrics; Multivariate methods; Pre-processing; Solid dispersions; Drug dissolution; Polymeric microparticles;
Keywords: پراکندگی جامد; Cystic echinococcosis; Echinococcus granulosus; Albendazole; Solid dispersions;
Keywords: پراکندگی جامد; Benznidazole; Solid dispersions; Physicochemical characterization; Dissolution study; Trypanocidal activity;
Keywords: پراکندگی جامد; polyethylene glycol (PEG); solid dispersions; physical characterization; solubility; miscibility; crystallinity; thermal analysis; powder X‐ray diffraction; pair distribution function
Keywords: پراکندگی جامد; Hot-melt extrusion; Solid dispersions; Polymer matrix; Glass-transition temperature; Amorphous; Crystallinity;
Keywords: پراکندگی جامد; Artemisinin; Solid dispersions; Solubility parameter; Miscibility; Molecular dynamics; Permeability coefficient;
Keywords: پراکندگی جامد; Solid dispersions; Hot melt extrusion; Spray drying; Amorphous; Dissolution; Compactibility;
Effect of HPMCAS on recrystallization inhibition of nimodipine solid dispersions prepared by hot-melt extrusion and dissolution enhancement of nimodipine tablets
Keywords: پراکندگی جامد; Nimodipine; HPMCAS; Recrystallization inhibition; Solid dispersions; Hot-melt extrusion; Bioavailability;
Assessing the potential of solid dispersions to improve dissolution rate and bioavailability of valsartan: In vitro-in silico approach
Keywords: پراکندگی جامد; Solid dispersions; Poorly soluble drugs; Bioavailability; in silico modeling;
Solid dispersions to enhance the delivery of a potential drug candidate LPSF/FZ4 for the treatment of schistosomiasis
Keywords: پراکندگی جامد; Schistosomiasis; Solid dispersions; Solubility enhancement; Drug candidate; Supersaturation; Bioavailability;
The pharmacokinetics and anti-inflammatory effects of chelerythrine solid dispersions in vivo
Keywords: پراکندگی جامد; CHE; Solid dispersions; Pharmacokinetic; Anti-inflammation;
Research paperEudragit® RL as a stabilizer for supersaturation and a substrate for nanocrystal formation
Keywords: پراکندگی جامد; Solid dispersions; Eudragit RL; Supersaturation; Nanocrystals; Thermal analysis; X-ray powder diffraction; Spray drying; INDO; indomethacin; NAP; naproxen; CINN; cinnarizine; ERL; Eudragit RL; PVP; polyvinylpyrrolidone; Tg; glass transition temperature; m
Application of miscibility analysis and determination of Soluplus solubility map for development of carvedilol-loaded nanofibers
Keywords: پراکندگی جامد; Poorly soluble drugs; Solvent mapping; Electrospinning; Solid dispersions; Solubility enhancement; Interaction parameter;
Sodium alginate as a potential carrier in solid dispersion formulations to enhance dissolution rate and apparent water solubility of BCS II drugs
Keywords: پراکندگی جامد; Telmisartan; Sodium alginate; Solid dispersions; Mechanical grinding process
Unexpected solvent impact in the crystallinity of praziquantel/poly(vinylpyrrolidone) formulations. A solubility, DSC and solid-state NMR study
Keywords: پراکندگی جامد; Praziquantel (PubChem CID: 4891); PZQ; praziquantel; PVP; poly(vinylpyrrolidone); NMR; nuclear magnetic resonance; DSC; differential scanning calorimetry; SEM; scanning electron microscopy; PMs; physical mixtures; SDs; solid dispersions; Praziquantel; Pol
Hot melt extruded transdermal films based on amorphous solid dispersions in Eudragit RS PO: The inclusion of hydrophilic additives to develop moisture-activated release systems
Keywords: پراکندگی جامد; Transdermal; Polymeric drug delivery systems; Amorphous; Solid dispersions; hot melt extrusion; Hydration; Excipients; Physicochemical characterization;
Enhanced hypotensive effect of nimodipine solid dispersions produced by supercritical CO2 drying
Keywords: پراکندگی جامد; Nimodipine; PVP K-30; Solid dispersions; Supercritical fluid technology
Pharmacological and histological examination of atorvastatin-PVP K30 solid dispersions
Keywords: پراکندگی جامد; Atorvastatin; Solid dispersions; Physicochemical characterization; Histological examination; Pharmacological efficiency
Influence of formulation composition and process on the characteristics and in vitro release from PLGA-based sustained release injectables
Keywords: پراکندگی جامد; Solid dispersions; PLGA; PVP; Dissolution; Microspheres; Controlled release; MDSC; ToF-SIMS; Surface analysis
In vivo evaluation of different formulation strategies for sustained release injectables of a poorly soluble HIV protease inhibitor
Keywords: پراکندگی جامد; Solid dispersions; PLGA; Microspheres; Controlled release; In vivo;
Molecular interaction between glimepiride and Soluplus®-PEG 4000 hybrid based solid dispersions: Characterisation and anti-diabetic studies
Keywords: پراکندگی جامد; Solid dispersions; Anti-diabetic; Hybrid polymers; Bioavailability; Soluplus®; Dissolution studies; Glimepiride;
Structural insight into the physical stability of amorphous Simvastatin dispersed in pHPMA: Enhanced dynamics and local clustering as evidenced by solid-state NMR and Raman spectroscopy
Keywords: پراکندگی جامد; Solid dispersions; Simvastatin; Pharmaceuticals; Solid-state NMR; Raman spectroscopy; Fluorescence
Development and evaluation of gastroretentive raft forming systems incorporating curcumin-Eudragit® EPO solid dispersions for gastric ulcer treatment
Keywords: پراکندگی جامد; Curcumin; Raft forming systems; Solid dispersions; Stomach-specific delivery; Gastric ulcers;
A new combination approach of CI jet and QESD to formulate pH-susceptible amorphous solid dispersions
Keywords: پراکندگی جامد; ASDs; Amorphous solid dispersions; BCS; Biopharmaceutics classification system; BI; Boehringer Ingelheim Pharmaceuticals; CIJ; Confined impinging jet; CQAs; Critical quality attributes; DCM; Dicholoromethane; HP-55; Hydroxypropyl methylcellulose phthalate
Matrix-Assisted Cocrystallization (MAC) Simultaneous Production and Formulation of Pharmaceutical Cocrystals by Hot-Melt Extrusion
Keywords: پراکندگی جامد; cocrystals; matrix; formulation; extrusion; continuous manufacturing; dissolution; supersaturation; crystal engineering; polymers; crystallization; solid dispersions
Hydrophilic polymer solubilization on norfloxacin solubility in preparation of solid dispersion
Keywords: پراکندگی جامد; Hydrophilic polymers; Norfloxacin; Polymer complexation; Solid dispersions;
Solid dispersion of berberine-phospholipid complex/TPGS 1000/SiO2: preparation, characterization and in vivo studies
Keywords: پراکندگی جامد; Berberine; Phospholipid-complex; TPGS 1000; Silica; Solid dispersions; P-glycoprotein;
Formulation and in vitro absorption analysis of Rhizoma paridis steroidal saponins
Keywords: پراکندگی جامد; SD; solid dispersions; PHY; phytosome; RPS; Rhizoma paridis steroidal saponin extract; PK 30; Povidone K-30; P 407; poloxamer 407; P 188; poloxamer 188; PEG 4000; polyethylene glycol 4000; PEG 6000; polyethylene glycol 6000; Steroidal saponins; Solid disp
Unexpected Performance of Physical Mixtures over Solid Dispersions on the Dissolution Behavior of Benznidazole from Tablets
Keywords: پراکندگی جامد; solid dispersions; dissolution; excipients; formulation; tablet;
Development of PVP/PEG mixtures as appropriate carriers for the preparation of drug solid dispersions by melt mixing technique and optimization of dissolution using artificial neural networks
Keywords: پراکندگی جامد; Melt mixing; Solid dispersions; Tibolone; PVP/PEG; Polymer blends; Artificial neural networks;
Sustained release solid lipid matrices processed by hot-melt extrusion (HME)
Keywords: پراکندگی جامد; Extrusion; Lipids; Solid dispersions; Tablet; Solid dosage form;
Impact of amorphous and semicrystalline polymers on the dissolution and crystallization inhibition of pioglitazone solid dispersions
Keywords: پراکندگی جامد; Solid dispersions; Active pharmaceutical ingredients; Amorphous polymers; Semicrystalline polymers; Crystallization inhibition; A supersaturated state;
Effect of drug–polymer interactions on the aqueous solubility of milled solid dispersions
Keywords: پراکندگی جامد; Saturation solubility; Solid dispersions; Drug–polymer interactions; Particle size; Crystallization
A novel lipid-based solid dispersion for enhancing oral bioavailability of Lycopene – In vivo evaluation using a pig model
Keywords: پراکندگی جامد; Lycopene bioavailability; Lipid-based formulation; SEDDS; Solid dispersions; Gelucire 44/14; Pig model
Characterization of solid polymer dispersions of active pharmaceutical ingredients by 19F MAS NMR and factor analysis
Keywords: پراکندگی جامد; Solid-state NMR; Factor analysis; 19F MAS NMR; API; Solid dispersions; Magnetic susceptibility