Inhibition of ceramide de novo synthesis by myriocin produces the double effect of reducing pathological inflammation and exerting antifungal activity against A. fumigatus airways infection
Keywords: BALT; Bronchial Associated Lymphoid Tissue; CF; Cystic Fibrosis; COPD; Chronic Obstructive Pulmonary Disease; CFTR; CF transmembrane conductance regulator; CFU; Colony Forming Units; Gapdh; glyceraldehyde-3-phosphate dehydrogenase; HO1; heme oxygenase 1;