Interleukin 6 inhibits the differentiation of rat stem Leydig cells
Keywords: آمار; IL-6; Stem Leydig cells; Proliferation; Differentiation; JAK1; STAT;
مقالات ISI آمار (ترجمه نشده)
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Clinical variables and ethnicity may influenced by polymorphism of CAT â262C/T and MnSOD 47C/T antioxidant enzymes in Algerian type1 diabetes without complications
Keywords: آمار; T1D; type1 diabetes; CAT; Catalase; MnSOD; manganese superoxide dismutase; SOD; superoxide dismutase; WHO; World Health Organization; TAHINA; survey Transition And Health Impact in North Africa; INSP; National Institute of Public Health; ROS; Reactive oxy
gga-miR-454 suppresses infectious bursal disease virus (IBDV) replication via directly targeting IBDV genomic segment B and cellular Suppressors of Cytokine Signaling 6 (SOCS6)
Keywords: آمار; MicroRNA; Type I IFN; IBDV; SOCS; STAT;
STAT3: The art of multi-tasking of metabolic and immune functions in obesity
Keywords: آمار; Signal transducer and activator of transcription 3; Obesity; Metabolism; Lipid; Immune; AgRP; Agouti-related peptide; AMPK; AMP-activated protein kinase; AOX; acyl-CoA oxidase; ARC; arcuate nucleus; ATGL; adipose triglyceride lipase; BAT; brown adipose ti
Flaviviridae virus nonstructural proteins 5 and 5A mediate viral immune evasion and are promising targets in drug development
Keywords: آمار; AAF; IFN-α-activated factor; ATA; Aurintricarboxylic acid; BDV; border disease virus; BPgV; GBV-D; BVDV-1; bovine viral diarrhea virus-1; C; capsid protein; CLRs; C-type lectin receptors; Core; core protein; CSFV; classical swine fever virus; DENV; dengu
Biallelic interferon regulatory factor 8 mutation: AÂ complex immunodeficiency syndrome with dendritic cell deficiency, monocytopenia, and immune dysregulation
Keywords: آمار; Interferon regulatory factor 8; immunodeficiency; dendritic cell; monocyte; myeloproliferation; interferon; AICE; Activator protein 1-interferon regulatory factor composite element; BAL; Bronchoalveolar lavage; cDC; Conventional dendritic cell; CDR3; Co
The role of TAM family receptors and ligands in the nervous system: From development to pathobiology
Keywords: آمار; ACSF; artificial cerebral spinal fluid; APP; amyloid precursor protein; BBB; blood-brain-barrier; BCECs; brain capillary endothelial cells; C57Bl6/J; strain of mice for MOG-induce EAE and cuprizone studies; CNS; central nervous system; DKO; Gas6â/âAxl
Protein tyrosine phosphatase conjugated with a novel transdermal delivery peptide, astrotactin 1-derived peptide recombinant protein tyrosine phosphatase (AP-rPTP), alleviates both atopic dermatitis-like and psoriasis-like dermatitis
Keywords: آمار; Atopic dermatitis; psoriasis; transdermal delivery peptide; protein tyrosine phosphatase; T-cell protein tyrosine phosphatase; transcutaneous drug; immunomodulatory protein; AD; Atopic dermatitis; AP; Astrotactin 1-derived peptide; CHS; Contact hypersen
Phosphatase wild-type p53-induced phosphatase 1 controls the development of TH9 cells and allergic airway inflammation
Keywords: آمار; Allergy; Wip1; TH9 cell development; IL-9; phosphatase; AP-1; Activator protein 1; BAL; Bronchoalveolar lavage; BATF; Basic leucine zipper ATF-like transcription factor; ChIP; Chromatin immunoprecipitation; dLN; Draining lymph node; Foxp3; Forkhead box pr
Autophagy as a pharmacological target in hematopoiesis and hematological disorders
Keywords: آمار; 3-MA; 3-methyladenine; ALL; acute lymphoblastic leukemia; AMKL; acute megakaryoblastic leukemia; AML; acute myeloid leukemia; AMPK; 5â²-adenosine monophosphate-activated protein kinase; APL; acute promyelocytic leukemia; Atg; autophagy-related proteins;
The role of T cells in the pathogenesis of Parkinson's disease
Keywords: آمار; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; APC; antigen-presenting cell; AQP4; Aquaporin-4; BBB; blood-brain barrier; BCL6; B cell lymphoma 6; BCR; B cell receptor; BEC; brain endothelial cells; CCL20; C-C motif ligand 20; CCR2; C-C
STAT6 silencing induces hepatocellular carcinoma-derived cell apoptosis and growth inhibition by decreasing the RANKL expression
Keywords: آمار; STAT6; signal transducer and activator of transcription-6; HCC; hepatocellular carcinoma; RANKL; receptor activator of NF-κB ligand; RFA; radiofrequency ablation; OPG; osteoprotegerin; TNFR; tumor necrosis factor receptor; I/R; ischemia/reperfusion; STAT
Hypoxia-induced activation of specific members of the NF-kB family and its relevance to pulmonary vascular remodeling
Keywords: آمار; pH; pulmonary hypertension; SMC; human pulmonary artery smooth muscle cells; EC; human pulmonary microvascular endothelial cells HPMECSt1.6R; NF-kB; nuclear factor kappa-light-chain-enhancer of activated B cells; RelA; v-rel avian reticuloendotheliosis vi
The JAK/STAT signaling pathway and photobiomodulation in chronic wound healing
Keywords: آمار; AP; activator protein; ATP; adenosine triphosphate; Ca2+; calcium ions; cAMP; cyclic adenosine monophosphate; Cox; cytochrome c oxidase; Cu; copper; Cyto c; cytochrome c; DNA; deoxyribonucleic acid; ECM; extracellular matrix; EGF; epidermal growth factor;
High fat diet-induced obesity increases myocardial injury and alters cardiac STAT3 signaling in mice after polymicrobial sepsis
Keywords: آمار; CLP; cecal ligation and puncture; cTnI; cardiac troponin; STAT; signal transducer and activator of transcription; SOCS3; suppressor of the cytokine signaling family; Sepsis; Obesity; STAT3; Cardiac inflammation;
Tumour-associated macrophages activate migration and STAT3 in pancreatic ductal adenocarcinoma cells in co-cultures
Keywords: آمار; Macrophages; Pancreatic cancer; Invasion; STAT; Polarization;
Effect of luteolin on inflammatory responses in RAW264.7 macrophages activated with LPS and IFN-γ
Keywords: آمار; LPS; lipopolysaccharide; IFN-γ; interferon-γ; iNOS; inducible nitric oxide synthase; IL-1β; interleukin-1β; CD; cluster of differentiation; TNF; tumour necrosis factor; STAT; signal transducer and activator of transcription; HPLC; high performance liq
Tofacitinib ameliorates inflammation in a rat model of airway neutrophilia induced by inhaled LPS
Keywords: آمار; JAK; Inhaled LPS rat model; Tofacitinib; Lung inflammation; BALF; STAT3; BALF; bronchoalveolar lavage fluid; JAK; janus kinase; LPS; lipopolysaccharide; pSTAT3; phosphorylated STAT3; STAT; signal transducers and activators of transcription; TLR; toll-like
Interleukin-10 inhibits neuroinflammation-mediated apoptosis of ventral mesencephalic neurons via JAK-STAT3 pathway
Keywords: آمار; PD; Parkinson's disease; IL-10; interleukin-10; IL-10R; interleukin-10 receptor; LPS; lipopolysaccharide; TH; tyrosine hydroxylase; TNF-α; tumor necrosis factor-α; BDNF; brain derived neurotrophic factor; JAK; Janus kinase; STAT; signal transducer and a
STAT3 activation in infection and infection-associated cancer
Keywords: آمار; Bacteria; Colon cancer; Inflammation; Infection; JAK; Salmonella; STAT; STAT3; STAT5; Virus;
The evolutionary divergence of STAT transcription factor in different Anopheles species
Keywords: آمار; STAT; Signal Transducer and Activator of Transcription; JAK; Janus kinase; NJ; Neighbor-Joining; An.; Anopheles; MEGA; Molecular Evolutionary Genetics Analysis; UTR; untranslated region; MYA; million years ago; P. berghei; Plasmodium berghei; SOCS; suppre
The good and the bad faces of STAT1 in solid tumours
Keywords: آمار; BAD; Bcl2-associated agonist of cell death; Bcl; B-cell lymphoma; CD; cluster of differentiation; CDK; cyclin-dependent kinase; CTL; cytotoxic T lymphocyte; CUG; cancer upregulated gene; CXCL; C-X-C motive ligand; DC; dendritic cells; DAMP; danger-associa
Characterization of non-lethal West Nile Virus (WNV) infection in horses: Subclinical pathology and innate immune response
Keywords: آمار; Flavivirus; Arbovirus; Equine; Interferons; Innate immune response; CNS; central nervous system; CXCL10; chemokine (C-X-C motif) ligand 10; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; HE; hematoxylin and eosin; HIF-1α; hypoxia inducible factor 1α; IF
JAK/STAT disruption induces immuno-deficiency: Rationale for the development of JAK inhibitors as immunosuppressive drugs
Keywords: آمار; JAK; STAT; Immunosuppression; Myeloproliferative neoplasia; Autoimmunity; GVHD;
Crosstalk between STAT5 activation and PI3K/AKT functions in normal and transformed mammary epithelial cells
Keywords: آمار; Signal transduction; Janus kinase; STAT; Phosphatidylinositol 3-Kinases; Proto-oncogene proteins c-akt; Mammary gland development; Breast cancer;
Mitogen-activated protein kinase phosphatase 1 (MKP-1) in macrophage biology and cardiovascular disease. A redox-regulated master controller of monocyte function and macrophage phenotype
Keywords: آمار; ANP; Atrial natriuretic peptide; ARE; AU-rich elements; CS; catalytic sequence; DUSP; dual-specificity phosphatases; ERK; extracellular signal-regulated kinase; Grx; glutaredoxin; HA; hyaluronic acid; IFN; Interferon; IL; Interleukin; JNK; c-Jun N-termina
Adipose-Derived Stem Cells Protect Skin Flaps against Ischemia/Reperfusion Injury via IL-6 Expression
Keywords: آمار; ADSC; adipose-derived stem cell; CM; conditioned medium; ERK; extracellular signal-regulated kinase; Exo; exosome; I/R; ischemia/reperfusion; KO; knockout; MSC; mesenchymal stem cell; p-; phosphorylated; STAT; signal transducer and activator of transcri
Perioperative NT-proBNP level: Potential prognostic markers in children undergoing congenital heart disease surgery
Keywords: آمار; N-terminal pro-brain natriuretic peptide; congenital heart disease; surgery; predictor; children; ACC; aorta crossclamp; AKI; acute kidney injury; AUC; area under the curve; CHD; congenital heart disease; CICU; cardiac intensive care unit; CPB; cardiopu
Fluoro and pentafluorothio analogs of the antitumoral curcuminoid EF24 with superior antiangiogenic and vascular-disruptive effects
Keywords: آمار; CA/VM; chorioallantoic/vitelline membrane; COX; cyclooxygenase; DMEM; Dulbecco's modified Eagle medium; dpf; days past fertilization; FBS; fetal bovine serum; hpa; hours past application; hpf; hours past fertilization; HRP; horseradish peroxidase; mAb;
Age-related remodeling of the JAK/STAT/SOCS signaling pathway and associated myocardial changes: From histological to molecular level
Keywords: آمار; JAK; STAT; Aging; Histology; Immunohistochemistry;
Liver immunology: How to reconcile tolerance with autoimmunity
Keywords: آمار; PPR; pattern recognition receptor; HBV; hepatitis B virus; HCV; hepatitis C virus; TLR; toll-like receptor; IFN; interferon; LSEC; liver sinusoidal endothelial cell; APC; antigen presenting cell; MHC; major histocompatibility complex; PDL-1; program death
Carp Il10a and Il10b exert identical biological activities in vitro, but are differentially regulated in vivo
Keywords: آمار; Interleukin-10; Teleost; Paralogues; Gene duplication; APCs; antigen presenting cells; RTqPCR; real-time quantitative PCR; CTL; cytotoxic T lymphocyte; Socs3; suppressor of cytokine signaling 3; AP-1; activator protein-1; AP1R; MAF and AP1 related factors
Therapeutic effect of Cryptotanshinone on experimental rheumatoid arthritis through downregulating p300 mediated-STAT3 acetylation
Keywords: آمار; RA; rheumatoid arthritis; CTS; Cryptotanshinone; DMARDs; disease-modifying anti-rheumatic drugs; FLS; fibroblast-like synoviocytes; CIA; type-II collagen-induced arthritis; STAT; Signal transducer and activator of transcription; IGU; iguratimod; Treg; reg
The Society of Thoracic Surgeons Congenital Heart Surgery Database: 2017 Update on Research
Keywords: آمار; CCAS; Congenital Cardiac Anesthesia Society; CHD; congenital heart disease; CHSD; Congenital Heart Surgery Database; CI; confidence interval; DCRI; Duke Clinical Research Institute; DHCA; deep hypothermic circulatory arrest; dSLO; duration of sternum left
Attenuated in vitro effects of IFN-α, IL-2 and IL-12 on functional and receptor characteristics of peripheral blood lymphocytes in metastatic melanoma patients
Keywords: آمار; NK; natural Killer; CTL; cytotoxic T lymphocytes; MM; metastatic melanoma; NKG2D; natural killer group 2 D; NCR; natural cytotoxicity receptor; KIR; killer cell immunoglobulin-like receptor; HLA; human leukocyte antigen; MICA/B; MHC-class-I-polypeptide-re
Diversity of fungal assemblages in roots of Ericaceae in two Mediterranean contrasting ecosystems
Keywords: آمار; BLAST; basic local alignment search tool; DNA; deoxyribonucleic acid; DSE; dark septate endophytes; ErM; ericoid mycorrhizae; ITS; internal transcribed spacer; K; potassium; MA; malt agar; MCA; multiple correspondence analysis; MMN; modified Melin-Norkr
The role of interleukin-17A in the pathogenesis of kidney diseases
Keywords: آمار; Interleukin-17A; inflammation; kidney disease; AHR; aryl hydrocarbon receptor; AKI; acute kidney injury; ANCA; antineutrophil cytoplasmic antibody; APOE; apolipoprotein E; ASC; apoptosis-associated speck-like protein containing a carboxy-terminal CARD; Ct
Trisubstituted purine inhibitors of PDGFRα and their antileukemic activity in the human eosinophilic cell line EOL-1
Keywords: آمار; PDGFRα; platelet derived growth factor receptor alpha; CDK2; cyclin-dependent kinase 2; TK; tyrosine kinase; MAPK; mitogen-activated protein kinase; STAT; signal transducers and activators of transcription;
Helicobacter pylori Infection Promotes Methylation and Silencing of Trefoil Factor 2, Leading to Gastric Tumor Development in Mice and Humans
Keywords: آمار; Tumor Suppressor; Epigenetics; Stomach Cancer; Trefoil Factor 2; 5â²-Aza-C; 5â²-aza-2â²-deoxycytidine; AB/PAS; alcian blue periodic acid-Schiff; Erk; extracellular signal-regulated kinase; IFN; interferon; IL; interleukin; IM; intestinal metaplasia; MN
JAK-inhibitor tofacitinib suppresses interferon alfa production by plasmacytoid dendritic cells and inhibits arthrogenic and antiviral effects of interferon alfa
Keywords: آمار; CMV; cytomegalovirus; HCV; hepatitis C virus; IFNα; interferon alpha; JAK; Janus kinase; PBMC; peripheral blood mononuclear cells; PDCs; plasmacytoid dendritic cells; RA; rheumatoid arthritis; RASFs; rheumatoid arthritis synovial fibroblasts; SLE; system
Treatment of Hypereosinophilic Syndrome with Cutaneous Involvement with the JAK Inhibitors Tofacitinib and Ruxolitinib
Keywords: آمار; HES; hypereosinophilic syndrome; JAK; Janus kinase; L-HES; lymphocytic variant HES; STAT; signal transducer and activator of transcription; Th2; T helper type 2;
MicroRNA-21 drives severe, steroid-insensitive experimental asthma by amplifying phosphoinositide 3-kinase-mediated suppression of histone deacetylase 2
Keywords: آمار; Severe asthma; corticosteroids; airway hyperresponsiveness; miR-21; PI3 kinase; histone deacetylase 2; Chlamydia species; Haemophilus influenzae; influenza; respiratory syncytial virus; AAD; Allergic airway disease; AHR; Airway hyperresponsiveness; Ant-21
Ruxolitinib reverses dysregulated T helper cell responses and controls autoimmunity caused by a novel signal transducer and activator of transcription 1 (STAT1) gain-of-function mutation
Keywords: آمار; STAT1 gain of function; IFN-γ; ruxolitinib; autoimmunity; TH1 cell; TH17 cell; follicular T helper cell; T helper cell polarization; ATG; Anti-thymocyte globulin; BSA; Body surface area; GOF; Gain of function; IC50; Half-maximal inhibitory concentration
Functional analyses of the interaction of chicken interleukin 23 subunit p19 with IL-12 subunit p40 to form the IL-23 complex
Keywords: آمار; JAK; Janus kinase; STAT; signal transducer and activator of transcription; SOCS; suppressor of cytokine signaling; TYK2; tyrosine kinase 2; NF-κB; nuclear factor kappa B; C/EBP; CCAAT-enhancer-binding proteins; GATA-1; GATA-binding factor 1; AP-1; Activa
Original ArticleMACC1 regulates Fas mediated apoptosis through STAT1/3 - Mcl-1 signaling in solid cancers
Keywords: آمار; Solid cancers; MACC1; STAT signaling; Fas mediated apoptosis; Bcl-2 family proteins; MACC1; Metastasis associated in colon cancer 1; CRC; Colorectal cancer; STAT; Signal transducers and activators of transcription; JAK; Janus kinase; Mcl-1; Myeloid cell l
Studies of CDK 8/19 inhibitors: Discovery of novel and selective CDK8/19 dual inhibitors and elimination of their CYP3A4 time-dependent inhibition potential
Keywords: آمار; ADME; absorption, distribution, metabolism, and excretion; AML; acute myelogenous leukemia; AUC; area under the blood concentration time curve; b.i.d.; twice a day; CDK; Cyclin-dependent kinase; CLtotal; clearance; Cmax; maximum drug concentration; CRC; c
The 20Â kDa and 22Â kDa forms of human growth hormone (hGH) exhibit different intracellular signalling profiles and properties
Keywords: آمار; 22K-GH; 22Â kDa growth hormone; 20K-GH; 20Â kDa growth hormone; GHR; growth hormone receptor; JAK; Janus kinase; STAT; signal transducers and activators of transcription; 22Â kDa GH; 20Â kDa GH; Signalling pathway; JAK2-STAT5;
A Phase 1/2 Trial of Ruxolitinib and Erlotinib in Patients with EGFR-Mutant Lung Adenocarcinomas with Acquired Resistance to Erlotinib
Keywords: آمار; EGFR; Acquired resistance; Ruxolitinib; Erlotinib; JAK; STAT;
Molecular Classification of Hepatocellular Adenoma Associates With Risk Factors, Bleeding, and Malignant Transformation
Keywords: آمار; HCC; Tumor Progression; Benign; SHH; bex7,8HCA; β-catenin mutated hepatocellular adenoma in exon 7 or 8; bex7,8IHCA; β-catenin mutated inflammatory hepatocellular adenoma in exon 7 or 8; bex3IHCA; β-catenin mutated inflammatory hepatocellular adenoma i
AHR in the skin: From the mediator of chloracne to a therapeutic panacea?
Keywords: آمار; Arylhydrocarbon receptor; Skin; Inflammation; Dietary ligands; Air pollution; AHR; aryl hydrocarbon receptor; AHRR; AHR-repressor; TCDD; 2,3,7,8-tetrachlorodibenzo-p-dioxin; IDO; indoleamin-2,3,-dioxygenase; NFκB; nuclear factor κB; DC; dendritic cell;