دانلود مقالات ISI درباره Stearoyl-Coa Desaturase-1 + ترجمه فارسی

مشارکت اورکسین در تجمع چربی در کبد

Involvement of orexin in lipid accumulation in the liver

Keywords: Srebp1; Sterol regulatory element binding protein 1; Cd36; Cluster of differentiation 36; Ppar; Peroxisomal proliferator-activated receptor; Ucp2; Uncoupling protein 2; Socs3; STAT-induced suppressor of cytokine signaling 3; Fatp2/5; Fatty acid transporte

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

اسید اولئانوولی باعث افزایش چاقی ناشی از رژیم غذایی با تنظیم ترجیح چربی و التهاب در موش می شود

Oleanolic acid improves diet-induced obesity by modulating fat preference and inflammation in mice

Keywords: Oleanolic acid; High-fat diet; Fat taste perception; Inflammation; STD; Standard diet; HFD; High-fat diet; [Ca2+]i; free intracellular Ca2+ concentrations; OLA; Oleanolic acid; IGTT; Intraperitoneal glucose tolerance test; TL; Total lipid; TG; Triglycerid

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

گلیکوزید پلی آتییلن آسیب کلیه ایسکمیک را کاهش می دهد با همکاری مهار التهاب، اختلال در عملکرد میتوکندری و سمیت چربی

Polyacetylene glycoside attenuates ischemic kidney injury by co-inhibiting inflammation, mitochondria dysfunction and lipotoxicity

Keywords: AKI; acute kidney injury; ATP5a1; ATP synthase, H+ transporting, mitochondrial F1 complex, alpha 1; Bax; BCL2 associated X; BUN; blood urea nitrogen; CREA; serum creatinine; CC; creatinine clearance; CCK-8; cell counting kit-8; CD36; cluster of differenti

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2018 سفارش ترجمه

اجزای غذا با فعالیت ضد انعقاد و پیامدهای پیشگیری از بیماری کبد

Food components with antifibrotic activity and implications in prevention of liver disease

Keywords: ACC; acetyl-CoA carboxylase; ASTX; astaxanthin; BAMBI; BMP and activin membrane-bound inhibitor homolog; BDL; bile duct ligation; CCL4; chemokine (C-C motif) ligand 4; CCR; chemokine receptor C-C motif; ChREBP; carbohydrate response element binding protei

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2018 سفارش ترجمه

مصرف شربت ذرت با فروکتوز بالا باعث تغییر متابولیسم لیپیدی های کبدی و تجمع تری گلیسیرید می شود

High-fructose corn syrup-55 consumption alters hepatic lipid metabolism and promotes triglyceride accumulation

Keywords: ALT; alanine aminotransferase; ChREBP; carbohydrate response element binding protein; CXCL10; CXC motif chemokine ligand 10; DGAT2; diglyceride acyltransferase 2; DNL; de novo lipogenesis; FAME; fatty acid methyl ester; FAS; fatty acid synthase; GAPDH; gl

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2017 سفارش ترجمه

آسیب های کبدی در موش های چاق / دیابتی به علت ارتقاء لیپولیز آدپیوسیت و مهار واژن کبدی

Branched Chain Amino Acids Cause Liver Injury in Obese/Diabetic Mice by Promoting Adipocyte Lipolysis and Inhibiting Hepatic Autophagy

Keywords: β-AR; β-adrenergic receptor; 4-HNE; 4-hydroxynonenal; ACC; acetyl-coA carboxylase; ALT; alanine aminotransferase; AMPK; adenosine monophosphate-activated protein kinase; ANOVA; analysis of variance; AST; aspartate transaminase; ATGL; adipose triglycerid

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

بررسی اثربخشی و ریسک درمانهای ضد دیابتی: تجویز داروهای سنتی - تجدیدنظر مکانیکی برای درک نحوه عملکرد آنها

Efficacy and risk profile of anti-diabetic therapies: Conventional vs traditional drugs-A mechanistic revisit to understand their mode of action

Keywords: GLUT; Glucose transporter; T1DM; Type-1 diabetes mellitus; T2DM; Type-2 diabetes mellitus; PKB/Akt; protein kinase B; GSK-3; glycogen synthase kinase-3; PGC-1α; peroxisome proliferator-activated receptor gamma coactivator-1α; FOXO; forkhead box O; VLDL;

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2016 سفارش ترجمه

ارزیابی سیستماتیک بیوایستئید آمید که منجر به کشف مهار کننده های تیزی ایزولولی میداازولیدین جدید و قوی در درمان بیماری های متابولیکی می شود

Systematic evaluation of amide bioisosteres leading to the discovery of novel and potent thiazolylimidazolidinone inhibitors of SCD1 for the treatment of metabolic diseases

Keywords: Stearoyl-CoA desaturase-1; SCD1 inhibitors; Amide bioisosteres; Thiazolylimidazolidinone; Desaturation index;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

درمان استروئید غیرطبیعی، پروتئین لیپیدی میلین را در نوروپاتی محیطی دیابتی متبلور می کند

Neuroactive steroid treatment modulates myelin lipid profile in diabetic peripheral neuropathy

Keywords: Progesterone; Testosterone; Metabolites; Streptozotocin; Peripheral nerve; 3α-diol; 5α-androstane-3α,17β-diol; ACC; acetyl-CoA carboxylase α; AR; androgen receptor; DPN; diabetic peripheral neuropathy; DHP; dihydroprogesterone; ESI; electrospray ioni

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

سازگاری متابولیک با محدودیت های متیونین که به سلامتی و طول عمر در جوندگان کمک می کند

Metabolic adaptations to methionine restriction that benefit health and lifespan in rodents

Keywords: ACC; acetyl-CoA carboxylase; Ahcy; adenosylhomocysteinase; AT; adipose tissue; ATGL; adipose triglyceride lipase; AMPK; AMP-activated protein kinase; Bhmt; betaine-homocysteine S-methyltransferase; CR; caloric restriction; CBS; cystathionine β-synthase;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

زیست شناسی رادیکال آزاد برای پزشکی: یادگیری از بیماری کبدی چربی غیرالکلی

Free radical biology for medicine: learning from nonalcoholic fatty liver disease

Keywords: ROS; reactive oxygen species; NR; nuclear receptor; FA; fatty acid; TAG; triacylglycerol; MCD; malonyl-CoA decarboxylase; ACC; acetyl-CoA carboxylase; FAS; fatty acid synthase; SCD1; stearoyl-CoA desaturase-1; G-3-P; glycerol 3-phosphate; CPT-1; carnitine

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2013 سفارش ترجمه

Cissus quadrangularis extract (CQR-300) inhibits lipid accumulation by downregulating adipogenesis and lipogenesis in 3T3-L1 cells

Keywords: ACC; acetyl-CoA carboxylase; AMPK; AMP-activated protein kinase; aP2; fatty acid binding protein (aP2); BCS; bovine calf serum; C/EBPα; CCAAT/enhancer-binding protein α; CQR-300; Cissus quadrangularis extract; DMEM; Dulbecco's modified Eagle's mediu

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

Dietary grape seed proanthocyanidin extract regulates metabolic disturbance in rat liver exposed to lead associated with PPARα signaling pathway

Keywords: Hepatic fatty acids metabolism; Grape seed proanthocyanidin extract; Lead; Transcriptional regulation; PPARα signaling pathway; GSPE; Grape seed proanthocyanidin extract; PbA; Lead acetate; PPARα; Peroxisome proliferator-activated receptor alpha; ROS; R

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Exendin-4, a glucagon-like peptide-1 receptor agonist, reduces hepatic steatosis and endoplasmic reticulum stress by inducing nuclear factor erythroid-derived 2-related factor 2 nuclear translocation

Keywords: Glucagon-like peptide-1; Exendin-4; Nuclear factor erythroid-derived 2-related factor 2; Endoplasmic reticulum stress; Nonalcoholic fatty liver disease; ATF6; Activation transcription factor-6; Bip; Binding immunoglobulin protein; CHOP; C/EBP homologous p

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Long-term exposure to high-sucrose diet down-regulates hepatic endoplasmic reticulum-stress adaptive pathways and potentiates de novo lipogenesis in weaned male mice

Keywords: GAPDH; glyceraldehyde-3-phosphate dehydrogenase; ChREBP; carbohydrate-responsive element-binding protein; SREBP-1c; sterol regulatory element-binding protein 1c; SCD1; stearoyl-CoA desaturase-1; FASN; fatty acid synthase; CPT-1α; carnitine palmitoyltrans

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

PMFs-rich Citrus extract prevents the development of non-alcoholic fatty liver disease in C57BL/6J mice induced by a high-fat diet

Keywords: NAFLD; non-alcoholic fatty liver disease; NASH; non-alcoholic steatohepatitis; Nrf2; nuclear factor erythroid-2 related factor 2; DIO; diet -induced obese; TGs; triglycerides; ROS; reactive oxygen species; Keap1; Kelch-like ECH-associated protein 1; NQO1;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Polydatin prevents fructose-induced liver inflammation and lipid deposition through increasing miR-200a to regulate Keap1/Nrf2 pathway

Keywords: ASC; apoptosis-associated speck-like protein; CPT-1; carnitine palmitoyl transferase-1; GST; glutathione S-transferase; HO-1; hemeoxygenase-1; H2O2; hydrogen peroxide; IL; interleukin; Keap1; Kelch-like ECH-associated protein 1; MDA; malondialdehyde; miR-

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2018 سفارش ترجمه

High-fat diet alters PAS kinase regulation by fasting and feeding in liver

Keywords: ACC; acetyl CoA carboxylase; Akt/PKB; protein kinase B; CHREBP; carbohydrate-responsive element-binding protein; CPT1-A; carnitine palmitoyltransferase 1A; DAPI; 4,6-diamidino-2-phenylindole; FAS; fatty acid synthase; FOXO1; forkhead box protein O1; GCK;

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2018 سفارش ترجمه

A negative feedback loop between microRNA-378 and Nrf1 promotes the development of hepatosteatosis in mice treated with a high fat diet

Keywords: 3′UTRs; 3′ untranslated regions; Acad1; Acyl-coenzyme A dehydrogenase 1; Acox1; Acyl-coenzyme A oxidase 1; ASO; anti-sense oligonucleotide; ChIP; chromatin immunoprecipitation; Cpt1a; Carnitine palmitoyltransferase 1A; FAO; fatty acid oxidation; Fasn;

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2018 سفارش ترجمه

GCN2 deficiency protects against high fat diet induced hepatic steatosis and insulin resistance in mice

Keywords: ALT; alanine transaminase; AST; aspartate transaminase; Atgl; adipose triglyceride lipase; AU; arbitrary unit; AUC; area under the curve; BSA; bovine serum albumin; CHOP; C/EBP homologous protein; Cpt2; carnitine palmitoyltransferase 2; DHE; dihydroethidi

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2018 سفارش ترجمه

Natural products as modulators of the nuclear receptors and metabolic sensors LXR, FXR and RXR

Keywords: Natural products; Nuclear receptors; Liver X receptor; Farnesoid X receptor; Retinoid X receptor; Metabolic syndrome; Precision medicine; 6-ECDCA; 6α-ethyl-chenodeoxycholic acid (obeticholic acid); AA; arachidonic acid; ABC; ATP-binding cassette transpor

دانلود رایگان متن کامل مقاله ISI 78 صفحه سال انتشار : 2018 سفارش ترجمه

Experimental Nonalcoholic Steatohepatitis and Liver Fibrosis Are Ameliorated by Pharmacologic Activation of Nrf2 (NF-E2 p45-Related Factor 2)

Keywords: NASH; Nrf2; TBE-31; ACACA; acetyl-CoA carboxylase alpha; ACLY; ATP citrate lyase; ACOT7; acetyl-CoA thioesterase 7; ACOX2; acetyl-CoA oxidase 2; ADRP; adipose differentiation-related protein; AP-1; activator protein 1; ApoB; apolipoprotein B; ATF4; activa

دانلود رایگان متن کامل مقاله ISI 79 صفحه سال انتشار : 2018 سفارش ترجمه

Red paprika (Capsicum annuum L.) and its main carotenoid capsanthin ameliorate impaired lipid metabolism in the liver and adipose tissue of high-fat diet-induced obese mice

Keywords: NAFLD; non-alcoholic fatty liver disease; WAT; white adipose tissue; ND; normal diet; HD; high-fat diet; RP; red paprika-supplemented diet; CS; capsanthin-supplemented diet; TG; triacylglycerol; TC; total cholesterol; HDL; high-density lipoprotein; NEFA;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2017 سفارش ترجمه

Leptin concentrations and SCD-1 indices in classical homocystinuria: Evidence for the role of sulfur amino acids in the regulation of lipid metabolism

Keywords: AdoHcy; S-adenosylhomocysteine; AdoMet; S-adenosylmethionine; BIA; bioelectrical impedance analysis; BMD; bone mineral density; CβS; cystathionine β-synthase; DXA; dual X-ray absorptiometry; FAMEs; fatty acid methyl esters; GSH; glutathione; HCU; classi

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2017 سفارش ترجمه

Dihydrosterculic acid from cottonseed oil suppresses desaturase activity and improves liver metabolomic profiles of high-fat-fed mice

Keywords: Fatty acid oxidation; Desaturation; Metabolomics; Bioactive lipids; Nuclear magnetic resonance (NMR) spectroscopy; 18:2; linoleic acid-rich diet; 18:2n6; linoleic acid; CHO; carbohydrate; CPFA; cyclopropyl fatty acid; CSO; cottonseed oil; DHSA; dihydros

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2017 سفارش ترجمه

Honokiol activates the LKB1-AMPK signaling pathway and attenuates the lipid accumulation in hepatocytes

Keywords: ACC; acetyl-CoA carboxylase; AMPK; AMP-activated protein kinase; ATGL; adipose triglyceride lipase; CaMKK; calcium/calmodulin-dependent protein kinase kinase; FAS; fatty acid synthase; FFA; free fatty acid; HFD; high fat diet; Hon; honokiol; LKB1; liver k

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

The miR-200 family differentially regulates sensitivity to paclitaxel and carboplatin in human ovarian carcinoma OVCAR-3 and MES-OV cells

Keywords: Carboplatin; Drug resistance; Epithelial mesenchymal transition; miRNA-200; Paclitaxel; ALDH1A3; aldehyde dehydrogenase 1A3; AKR1C1 and AKRIC4; aldo-keto reductase family 1 and 4; CDH6; cadherin 6; COL5A1; collagen type V alpha 1; COL6A1; collagen type VI

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2015 سفارش ترجمه

Discovery of thiazolylpyridinone SCD1 inhibitors with preferential liver distribution and reduced mechanism-based adverse effects

Keywords: Stearoyl-CoA desaturase-1; SCD1 inhibitors; Thiazolylpyridinone; Liver selective; Desaturation index;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Research ArticleThioredoxin-interacting protein mediates hepatic lipogenesis and inflammation via PRMT1 and PGC-1α regulation in vitro and in vivo

Keywords: NAFLD; non-alcoholic fatty liver disease; NASH; non-alcoholic steatohepatitis; TXNIP; thioredoxin-interacting protein; PA; palmitic acid; SA; stearic acid; ACC; acetyl-CoA carboxylase; FAS; fatty acid synthase; SCD1; stearoyl-CoA desaturase-1; LPL; lipopr

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

LXR-α antagonist meso-dihydroguaiaretic acid attenuates high-fat diet-induced nonalcoholic fatty liver

Keywords: ABCA1, ABCG1; ATP-binding cassette transporter A1 or G1; AMPK; AMP-activated protein kinase; ACC; acetyl-coenzyme A carboxylase; FAS; fatty acid synthase; HDL; high density lipoprotein; HFD; high fat diet; LBD; ligand binding domain; LXR; liver X receptor

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Multi-faceted integrated omics analysis revealed parsley (Petroselinum crispum) as a novel dietary intervention in dextran sodium sulphate induced colitic mice

Keywords: AA; amino acid; Ala; alanine; Asn; asparagine; Asp; aspartic acid; Arg1; arginase 1; Ccl; chemokine (C-C motif) ligand; Cebp/d; CCAAT/enhancer binding protein (C/EBP), delta; Cd163; cluster of differentiation 163; Cxcl; chemokine (C-X-C motif) ligand; DAI

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Role of adipose tissue in methionine-choline-deficient model of non-alcoholic steatohepatitis (NASH)

Keywords: ATGL; adipose triglyceride lipase; ACC1; acetyl-CoA carboxylase; ACSL1; long-chain fatty-acid-coenzyme A ligase; ap2/FABP4; adipocyte protein 2/fatty acid binding protein 4; ATP5B; ATP synthase, H + transporting mitochondrial F1 complex, beta subunit; BA

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

The role of membrane fatty acid remodeling in the antitumor mechanism of action of 2-hydroxyoleic acid

Keywords: 2OHOA; 2-hydroxyoleic acid; DAG; diacylglycerol; DPH; 1,6-diphenyl-1,3,5-hexatriene; FAME; fatty acid methyl ester; HPTLC; high performance TLC; LUV; large unilamellar vesicle; MLV; multilamellar vesicle; MUFA; monounsaturated fatty acid; PC; phosphatidyl

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Omega-3 fatty acid deficiency augments risperidone-induced hepatic steatosis in rats: Positive association with stearoyl-CoA desaturase

Keywords: Omega-3 fatty acids; Risperidone; Atypical antipsychotic; Stearoyl-CoA desaturase-1; Oleic acid; Polyunsaturated fatty acids; Triglycerides; Glucose; Liver; Rat

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Ghrelin neutralization during fasting-refeeding cycle impairs the recuperation of body weight and alters hepatic energy metabolism

Keywords: 6PGDH; 6-phosphogluconate dehydrogenase; ACCα; acetyl-CoA carboxylase alpha; ACL; ATP citrate lyase; AKT; total serine/threonine kinase protein kinase B; AMPKα; 5′AMP-activated protein kinase alpha; CPT1A; liver isoform of carnitine palmitoyltransfera

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

Modulation of the hepatic fatty acid pool in peroxisomal 3-ketoacyl-CoA thiolase B-null mice exposed to the selective PPARalpha agonist Wy14,643

Keywords: Peroxisomal 3-ketoacyl-CoA thiolase B; PPARα; Mono-unsaturated fatty acids n-7 and n-9; Stearoyl-CoA desaturase-1; Wy14,643; ThB; peroxisomal 3-ketoacyl-CoA thiolase B; ThA; peroxisomal 3-ketoacyl-CoA thiolase A; ACOX-I; peroxisomal acyl-CoA oxidase-I; P

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه