دانلود مقالات ISI درباره TAM، تاموکسیفن + ترجمه فارسی

بررسی متابولیکی مقایسه شده بین دو مولکول گیرنده استروژن، ترمیفن و تاموکسیفن در میکروسوم های کبدی انسانی

Comparative metabolic study between two selective estrogen receptor modulators, toremifene and tamoxifen, in human liver microsomes

Keywords: TAM، تاموکسیفن; Toremifene; Tamoxifen; Metabolite kinetics; Bioactivation; CYP2D6; CYP3A4; CYP2C9; Pharmacogenomics; PolymorphismsTOR, toremifene; TAM, tamoxifen; SERM, selective estrogen receptor modulator; SSRI, selective serotonin reuptake inhibitor; 4OH, 4-hydroxy; N

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

کلسترول 5،6-اپوکسیدها: شیمی، بیوشیمی، سرنوشت متابولیک و سرطان

Cholesterol-5,6-epoxides: Chemistry, biochemistry, metabolic fate and cancer

Keywords: TAM، تاموکسیفن; 5,6-Epoxy-cholesterol; Cholesterol oxide; Cholesterol epoxide; Dendrogenin; Cancer; AEBS; antiestrogen binding site; ChEH; cholesterol epoxide hydrolase; Tam, tamoxifen; trans-2-[4-(1,2-diphenyl-1-butenyl)phenoxy]-N,N-dimethylethylamine; D8D7I; 3β-hydrox

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Tamoxifen-induced cytotoxicity in breast cancer cells is mediated by glucose-regulated protein 78 (GRP78) via AKT (Thr308) regulation

Keywords: TAM، تاموکسیفن; GRP78, glucose-regulated protein 78; UPR, unfolded protein response; TAX, paclitaxel; DOX, doxorubicin; 5-FU, 5 fluorouracil; TAM, tamoxifen; ER, estrogen receptorAKT signaling; Breast cancer; Chemoresistance; Endoplasmic reticulum stress; Tamoxifen

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Secretory prostate apoptosis response (Par)-4 sensitizes multicellular spheroids (MCS) of glioblastoma multiforme cells to tamoxifen-induced cell death

Keywords: TAM، تاموکسیفن; CM, conditioned medium; GBM, glioblastoma multiforme; LGG, low grade gliomas; MCS, multicellular spheroids; TAM, tamoxifen; TCGA, The Cancer Genome AtlasGlioblastoma; Par-4; Drug resistance; Multicellular spheroids (MCS); Tamoxifen; Cytotoxicity

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

PKCα inhibited apoptosis by decreasing the activity of JNK in MCF-7/ADR cells

Keywords: TAM، تاموکسیفن; PKC, protein kinase C; JNK, c-Jun NH2-terminal kinase; MDR, multidrug resistant; TAM, tamoxifen; DCC-FBS, fatal bovine serum stripped with dextrin-coated charcoal; SP, sp600125; Go, Go6976Apoptosis; MDR; PKCα; JNK; Breast cancer

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Importance of cholesterol and oxysterols metabolism in the pharmacology of tamoxifen and other AEBS ligands

Keywords: TAM، تاموکسیفن; AEBS, microsomal antiestrogen binding site; ER, estrogen receptor; PR, progesterone receptor; SERM, selective estrogen receptor modulator; Tam, tamoxifen; ACAT, Acyl-coA:Cholesterol Acyl-Transferase; SOAT, sterol O-acyltransferase; D8D7I, 3β-hydroxysterol

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

The effect of tamoxifen and raloxifene on estrogen metabolism and endometrial cancer risk

Keywords: TAM، تاموکسیفن; SERM, selective estrogen receptor modulator; EC, endometrial cancer; TAM, tamoxifen; RAL, raloxifene; EM1, nonmalignant immortalized human endometrial glandular cell line; EM, estrogen/estrogen metabolites; E2, estradiol; E1, estrone; HPLC–ESI-MS2, high p

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Locating the binding sites of anticancer tamoxifen and its metabolites 4-hydroxytamoxifen and endoxifen on bovine serum albumin

Keywords: TAM، تاموکسیفن; Endoxifen; Tamoxifen; BSA; Binding mode; Secondary structure; FTIR; CD; Fluorescence spectroscopyBSA, bovine serum albumin; Tam, tamoxifen; 4-Hydroxtam, 4-hydroxytamoxifen; Endox, endoxifen; Trp, tryptophan; FTIR, Fourier transform infrared spectroscopy;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Inhibition of MAP kinase promotes the recruitment of corepressor SMRT by tamoxifen-bound estrogen receptor alpha and potentiates tamoxifen action in MCF-7 cells

Keywords: TAM، تاموکسیفن; MAPK; Corepressor; Nuclear hormone receptor; TamoxifenERα, estrogen receptor alpha; TAM, tamoxifen; 4-OHT, 4-hydroxytamoxifen; MAPK, mitogen-activated protein kinase; SMRT, silencing mediator for retinoid and thyroid hormone receptors; PR, progesterone re

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Antitumor agents 270. Novel substituted 6-phenyl-4H-furo[3,2-c]pyran-4-one derivatives as potent and highly selective anti-breast cancer agents

Keywords: TAM، تاموکسیفن; ER, estrogen receptor; HER2, human epidermal growth factor receptor 2; SAR, structure–activity relationship; TAM, tamoxifen; DIEA, diisopropylethylamine; DMAP, 4-(dimethyl amino) pyridine; LDA, lithium diisopropylamide; TMEDA, tetramethylethylenediamine6-

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Effects of binary mixtures of estrogen and antiestrogens on Japanese medaka (Oryzias latipes)

Keywords: TAM، تاموکسیفن; DWC, dilution water control; E2, 17β-estradiol; EDC, endocrine-disrupting chemical; ER, estrogen receptor; GSI, gonadosomatic index; HSI, hepatosomatic index; LET, letrozole; SC, solvent control; TAM, tamoxifen; TBT, tributyltin; VTG, vitellogeninMixture;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

131I labeling of tamoxifen and biodistribution studies in rats

Keywords: TAM، تاموکسیفن; TAM, tamoxifen; 131I-TAM, 131I-labeled tamoxifen; 131I-Rec-TAM, biodistribution in rats after receptor saturationAntiestrogen; 131I; Iodogen (1,3,4,6-tetrachloro-3α,6α-diphenylglycouril); 131I-TAM

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Enterodiol and enterolactone, two major diet-derived polyphenol metabolites have different impact on ERα transcriptional activation in human breast cancer cells

Keywords: TAM، تاموکسیفن; ED, enterodiol; EL, enterolactone; ER, estrogen receptor; MMP, matrix metalloproteases; V, vehicle; E2, 17β-estradiol; Tam, tamoxifen; ICI, ICI 182, 780; DMEM, Dubelcco's modified Eagle's medium; FCS, fetal calf serum; RT, reverse transcription; PCR, poly

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Cost-utility of adjuvant hormone therapies with aromatase inhibitors in post-menopausal women with breast cancer: Upfront anastrozole, sequential tamoxifen-exemestane and extended tamoxifen-letrozole

Keywords: TAM، تاموکسیفن; Breast cancer; Aromatase inhibitors; Tamoxifen; Cost-utility analysisANA, anastrozole; EXE, exemestane; LET, letrozole; TAM, tamoxifen; ATAC, Arimidex, Tamoxifen Alone or in Combination trial; IES, international exemestane study; DFS, disease free surviva

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Loss of tumourigenicity of stably ERβ-transfected MCF-7 breast cancer cells

Keywords: TAM، تاموکسیفن; EMT, epithelial–mesenchymal transition; E2, 17β-estradiol; ERα, estrogen receptor alpha; ERβ, estrogen receptor beta; GFP, green fluorescence protein; ICI, ICI 182,780; tam, tamoxifen; wt, wild-typeBreast cancer; Cell cycle; Estrogen receptors; Xenograft

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Delayed and persistent ERK1/2 activation is required for 4-hydroxytamoxifen-induced cell death

Keywords: TAM، تاموکسیفن; Tam, tamoxifen; OHT, 4-hydroxytamoxifen; ER, estrogen receptor; ERK, extracellular signal-regulated kinase; EGF, epidermal growth factor; JNK, Jun N-terminal kinase; RNAi, RNA interference; SERM, selective estrogen receptor modulator; E2, 17β-estradiol; M

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2007 سفارش ترجمه