Keywords: TCR، گیرنده سلول T; CML, cell-mediated lympholysis; CTL, cytotoxic lymphocyte; CTLp, CTL precursors; MHC, major histocompatibility complex; PBMC, peripheral blood mononuclear cell; TCR, T-cell receptor; 51Cr, chromium-51; TNF-α, tumor necrosis factor-alphaCell-mediated lymph
مقالات ISI TCR، گیرنده سلول T (ترجمه نشده)
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CD4+HLA-G+ regulatory T cells: Molecular signature and pathophysiological relevance
Keywords: TCR، گیرنده سلول T; cAMP, cyclic adenosine monophosphate; CCR5, chemokine (C–C motif) receptor 5; CNS, central nervous system; FoxP3, forkhead box protein P3; GvHD, graft-versus-host disease; MS, multiple sclerosis; TCR, T-cell receptor; Teff, effector T cells; tTreg, thymus
Absence of CD4+ T cell help generates corrupt CD8+ effector T cells in sarcoma-bearing Swiss mice treated with NLGP vaccine
Keywords: TCR، گیرنده سلول T; NLGP, neem leaf glycoprotein; TCR, T-cell receptor; TDLN, tumor draining lymph node; KLRG1, killer cell lectin-like receptor subfamily G member 1; DCs, dendritic cells; CTL, cytotoxic T lymphocytes; IDO, indoleamine 2,3-dioxygenase; APC, antigen presentin
CD28 costimulatory signals in T lymphocyte activation: Emerging functions beyond a qualitative and quantitative support to TCR signalling
Keywords: TCR، گیرنده سلول T; MHC, major histocompatibility complex; TCR, T-cell receptor; APC, antigen presenting cell; Ig, immunoglobulin; IL, interleukin; IS, immunological synapse; PLCγ1, phospholipase Cγ1; LAT, linker for activation of T cells; Grb2, growth-factor receptor-bound
In-silico analysis of Pasteurella multocida to identify common epitopes between fowl, goat and buffalo
Keywords: TCR، گیرنده سلول T; FC, Fowl Cholera; HS, Haemorrhagic Septicaemia; OM, Outer membrane; APC, Antigen Presenting Cells; BCR, B-cell Receptors; MHC, Major Histocompatibility Complex; CTL, Cytotoxic T Lymphocytes; CD8, Cluster of Differentiation 8; TCR, T-cell Receptor; HTL, He
Association of UBASH3A gene polymorphisms and systemic lupus erythematosus in a Chinese population
Keywords: TCR، گیرنده سلول T; SLE, systemic lupus erythematosus; HWE, Hardy–Weinberg equilibrium; OR, odds ratio; CI, confidence interval; GWAS, genome-wide association study; IFC, Integrated Fluidic Circuit; PTPRT, protein tyrosine phosphatase receptor type; TCR, T-cell receptor; TUL
Modulation of human gamma/delta T-cell activation and phenotype by histone deacetylase inhibitors
Keywords: TCR، گیرنده سلول T; BrHPP, bromohydrin pyrophosphate; HDACi, histone deacetylase inhibitor; PHA, phytohaemagglutinin; PBMC, peripheral blood mononuclear cells; TCR, T-cell receptor; VPA, valproic acid; VPM, valpromideHistone deacetylation inhibitor; Valproic acid; Toxicity;
Redirection of Regulatory T Cells With Predetermined Specificity for the Treatment of Experimental Colitis in Mice
Keywords: TCR، گیرنده سلول T; CR, chimeric receptor; EAE, experimental allergic encephalitis; MBP, myelin basic protein; TNBS, 2,4,6-trinitrobenzene sulphonic acid; TCR, T-cell receptor; TPCR, tripartite chimeric receptor; Tregs, regulatory T cells
S100A4 regulates the Src-tyrosine kinase dependent differentiation of Th17 cells in rheumatoid arthritis
Keywords: TCR، گیرنده سلول T; mBSA, methylated bovine serum albumin; WT, wild-type; KO, knock-out; IFNγ, interferon-gamma; IL, interleukin; RORγt, retinoic acid orphan receptor gamma t; RA, rheumatoid arthritis; TNF, tissue necrosis factor; TCR, T-cell receptor; Th, helper T cell; STA
Role of Fas/FasL signaling in regulation of anti-viral response during HSV-2 vaginal infection in mice
Keywords: TCR، گیرنده سلول T; BMDC, bone marrow derived dendritic cell; DC, dendritic cell; HSV-2, herpes simplex virus type 2; IFN, interferon; MHC, major histocompatibility complex; NK cells, natural killer cells; STD, sexually transmitted diseases; TCR, T-cell receptor; TGF, transf
Peripheral accumulation of newly produced T and B lymphocytes in natalizumab-treated multiple sclerosis patients
Keywords: TCR، گیرنده سلول T; MS, multiple sclerosis; VLA-4, very late antigen-4; VCAM-1, vascular cell adhesion molecule 1; BBB, blood–brain barrier; CNS, central nervous system; BM, bone marrow; TCR, T-cell receptor; TRECs, T-cell receptor excision circles; KRECs, kappa-deleting rec
Clinical and histopathologic spectrum of alopecia mucinosa/follicular mucinosis and its natural history in children
Keywords: TCR، گیرنده سلول T; alopecia mucinosa; cutaneous T-cell lymphoma; follicular mucinosis; mycosis fungoidesAM, alopecia mucinosa; FM, follicular mucinosis; HL, Hodgkin lymphoma; ISCL, International Society of Cutaneous Lymphomas; MF, mycosis fungoides; TCR, T-cell receptor
Short-term immunological effects of non-ethanolic short-chain alcohols
Keywords: TCR، گیرنده سلول T; NFAT, nuclear factor of activated T cells; AP-1, activator protein-1; NF-κB, nuclear factor-κB; ERK, extracellular signal-regulated kinase; MAPK, mitogen-activated protein kinase; TLR4, Toll-like receptor 4; TCR, T-cell receptor; APC, antigen-presenting c
Genetically modulating T-cell function to target cancer
Keywords: TCR، گیرنده سلول T; TCR, T-cell receptor; MHC, major histocompatibility complex; HLA, human leukocyte antigen; ACT, adoptive cell transfer; CTL, cytotoxic T-cells; TAA, tumor associated antigens; OR, objective response; PR, partial responder; CR, complete responderGenetic im
Fish immune system and its nutritional modulation for preventive health care
Keywords: TCR، گیرنده سلول T; FAO, Food and Agriculture Organization; IgM, immunoglobulin M; GIT, gastrointestinal tract; GALT, gut associated lymphoid tissue; NCC, non-specific cytotoxic cells; MHC, major histocompatibility complex; IgT, immunoglobulin T; TCR, T-cell receptor; ELISA,
The molecular mechanisms of Foxp3 gene regulation
Keywords: TCR، گیرنده سلول T; Foxp3; CD4+ T cells; TGF-β; Id3; E2A; GATA3; c-RelTGF-β, transforming growth factor beta; Foxp3, forkhead box P3; TCR, T-cell receptor; Id3, inhibitor of DNA binding protein 3; E2A, basic Helix-Loop-Helix protein E2A; GATA3, trans-acting T-cell-specific t
Structural in silico analysis of cross-genotype-reactivity among naturally occurring HCV NS3-1073-variants in the context of HLA-A*02:01 allele
Keywords: TCR، گیرنده سلول T; HCV, Hepatitis C Virus; MHC, major histocompatibility complex; pMHC, MHC-peptide complex; HLA, human leukocyte antigen; TCR, T-cell receptor; PCA, principal component analysisCross-reactivity; Immunogenicity; Structural bioinformatics; Hepatitis C virus
T cell hybridomas to study MHC-II restricted B-cell receptor-mediated antigen presentation by human B cells
Keywords: TCR، گیرنده سلول T; APC, antigen presenting cell; BCR, B cell receptor; TCR, T-cell receptor; RT, reverse transcriptase; HAT, hypoxanthine/aminopterin/thymadineB cells; Antigen presentation; B cell receptor; MHC class II
Immune pathomechanism of drug hypersensitivity reactions
Keywords: TCR، گیرنده سلول T; Drug hypersensitivity; hapten; prohapten; p-i concept; dendritic cells; T lymphocytesp-i concept, Pharmacological interactions of drugs with immune receptors concept; SJS, Stevens-Johnson syndrome; TCR, T-cell receptor; TEN, Toxic epidermal necrolysis; Tr
Characterization of Interleukin-17–Producing Regulatory T Cells in Inflamed Intestinal Mucosa From Patients With Inflammatory Bowel Diseases
Keywords: TCR، گیرنده سلول T; Immune System; T-Cell Development; TGF-β; Immune SuppressionIFN, interferon; IL, interleukin; LP, lamina propria; MLN, mesenteric lymph node; PB, peripheral blood; TCR, T-cell receptor; TGF, transforming growth factor; Th17, T-helper interleukin-17–produc
KSR1 Protects From Interleukin-10 Deficiency-Induced Colitis in Mice by Suppressing T-Lymphocyte Interferon-γ Production
Keywords: TCR، گیرنده سلول T; KSR1; IL-10; IFN-γ; IL-17ABM, bone marrow; IBD, inflammatory bowel disease; IFN-γ, interferon-γ; IL, interleukin; KSR1, kinase suppressor of Ras 1; TCR, T-cell receptor; Th, T helper; TNF, tumor necrosis factor; VDR, vitamin-D receptor; WT, wild-type
Multiple myeloma patients at peripheral blood stem cell harvest: Restricted usage of TCR beta variable families
Keywords: TCR، گیرنده سلول T; RT–PCR, reverse transcription–polymerase chain reaction; TCRBV, T-cell receptor beta variable; TCR, T-cell receptor; BV, beta variable; PBMC, peripheral blood mononuclear cells; MM, multiple myeloma; PCR, polymerase chain reaction; ICT, initial chemothera
Towards a quantitative understanding of stem cell–niche interaction: Experiments, models, and technologies
Keywords: TCR، گیرنده سلول T; BM, bone marrow; CAFC, cobblestone area-forming cells; ECM, extracellular matrix; EGF, epidermal growth factor; HSC, hematopoietic stem cells; LTC, long-term culture; MSC, mesenchymal stem cells; PCA, principal component analysis; TCR, T-cell receptor; TN
Sulfatide-Mediated Activation of Type II Natural Killer T Cells Prevents Hepatic Ischemic Reperfusion Injury In Mice
Keywords: TCR، گیرنده سلول T; Ischemia; Liver Injury; Inflammation; CD1αGalCer, α-galactosyl ceramide; IFN, interferon; IRI, ischemic reperfusion injury; NKT, natural killer T; TCR, T-cell receptor; WT, wild type
CaMKII targets Bcl10 in T-cell receptor induced activation of NF-κB
Keywords: TCR، گیرنده سلول T; CaM, calmodulin; CaMK, CaM dependent kinase; TCR, T-cell receptor; PLC-γ, phospholipase C-γ; DAG, diacylglycerol; IP3, inositol 1,4,5-triphosphate; PKC, protein kinase C; CBM, Carma1, Bcl10, Malt1 complex; CARD, caspase recruitment domain; IKK, IκB kinase
Teleost IgSF immunoregulatory receptors
Keywords: TCR، گیرنده سلول T; Ig, immunoglobulin; NK, natural killer; IgSF, immunoglobulin superfamily; TCR, T-cell receptor; BCR, B-cell receptor; Chr, chromosome; FcR, Fc receptor; ADCC, antibody dependent cellular cytotoxicity; MHC I, major histocompatibility class I; KIR, killer I
Disparate Degrees of Hypervariable Loop Flexibility Control T-Cell Receptor Cross-Reactivity, Specificity, and Binding Mechanism
Keywords: TCR، گیرنده سلول T; TCR, T-cell receptor; CDR, complementarity-determining region; MHC, major histocompatibility complex; pMHC, peptide/MHC; HLA-A2, HLA-A⁎0201; MD, molecular dynamics; TRFA, time-resolved fluorescence anisotropy; TCSPC, time-correlated single-photon counting
T-Cell Receptor Signaling Enhances Transcriptional Elongation from Latent HIV Proviruses by Activating P-TEFb through an ERK-Dependent Pathway
Keywords: TCR، گیرنده سلول T; HIV, human immunodeficiency virus; TCR, T-cell receptor; P-TEFb, positive transcription elongation factor b; RNAP, RNA polymerase; TAR, transactivation response region; CycT1, cyclin T1; CDK, cyclin-dependent kinase; NELF, negative elongation factor; DRB,
Natural killer T cells are important in the pathogenesis of asthma: The many pathways to asthma
Keywords: TCR، گیرنده سلول T; Asthma; airway hyperreactivity; natural killer T cells; TH2 cells; innate immunityAHR, Airway hyperreactivity; BAL, Bronchoalveolar lavage; β2m, β2-Microglobulin; NKT, Natural killer T; TCR, T-cell receptor
Structural Basis for the Presentation of Tumor-Associated MHC Class II-Restricted Phosphopeptides to CD4+ T Cells
Keywords: TCR، گیرنده سلول T; MHC, major histocompatibility complex; MART-1, melanoma antigen recognized by T cells-1; pMART-1, MART-1 phosphopeptide; TCR, T-cell receptor; EBV, Epstein–Barr virus; GM-CSF, granulocyte–macrophage colony-stimulating factor; APC, antigen-presenting cell;
Hprt mutant frequency and p53 gene status in mice chronically exposed by inhalation to benzene
Keywords: TCR، گیرنده سلول T; CE, cloning efficiency; Hprt, hypoxanthine-guanine phosphoribosyltransferase; MFs, mutant frequencies; M-F, Monday–Friday; MWF, Monday–Wednesday–Friday; PigA, phosphatidylinositol glycan-class A; TCR, T-cell receptor; WT, wild-typeBenzene; Hprt; Loss of h
Age-related changes in immune function: Effect on airway inflammation
Keywords: TCR، گیرنده سلول T; Asthma; atopy; aging; elderly; immune function; immunosenescenceAM, Airway macrophage; BALF, Bronchoalveolar lavage fluid; Foxp3, Forkhead box protein 3; mDC, Myeloid dendritic cell; NK, Natural killer; ROS, Reactive oxygen species; TCR, T-cell receptor;
Biomolecular Network Reconstruction Identifies T-Cell Homing Factors Associated With Survival in Colorectal Cancer
Keywords: TCR، گیرنده سلول T; Integrative Biology; Colorectal Cancer; Chemokines; Immune ReactionCT, center; CRC, colorectal cancer; DFS, disease-free survival; HR, hazard ratio; IM, invasive margin; PCR, polymerase chain reaction; TCR, T-cell receptor; TH, T-helper–specific
Dissection of the IgNAR V Domain: Molecular Scanning and Orthologue Database Mining Define Novel IgNAR Hallmarks and Affinity Maturation Mechanisms
Keywords: TCR، گیرنده سلول T; CDR, complementarity determining region; HRP, horseradish peroxidase; PBS, phosphate-buffered saline; HBS-P, Hepes-buffered saline phosphate; RU, response units; Fw, framework; HEL, hen egg lysozyme; HV, hypervariable region; TCR, T-cell receptor; PBS-MB,
A fast and robust method to clone and functionally validate T-cell receptors
Keywords: TCR، گیرنده سلول T; UTR, untranslated region; TCR, T-cell receptor; PCR, polymerase chain reaction; wt, wild type; PMA, phorbol myristate acetate; NFAT, nuclear factor of activated T cellsTCR; T cells; Cellular immunology; Signal transduction; Immunotherapy
Presentation and Long-Term Follow-up of Refractory Celiac Disease: Comparison of Type I With Type II
Keywords: TCR، گیرنده سلول T; CT, computed tomography; EC, epithelial cell; GFD, gluten-free diet; IEL, intraepithelial lymphocyte; RCD, refractory celiac disease; TCR, T-cell receptor
Oligoclonal myelin-reactive T-cell infiltrates derived from multiple sclerosis lesions are enriched in Th17 cells
Keywords: TCR، گیرنده سلول T; NAWM, normal appearing white matter; MS, multiple sclerosis; CNS, central nervous system; TCR, T-cell receptor; CDR, complementarity-determining region; RORC, retinoic acid-related orphan nuclear hormone receptor C; PBMC, peripheral blood mononuclear cell
Celiac Disease: From Pathogenesis to Novel Therapies
Keywords: TCR، گیرنده سلول T; CCL25, chemokine ligand 25; CCR, chemokine receptor; EATL, enteropathy-associated T-cell lymphoma; IEL, intraepithelial lymphocyte; IFN, interferon; IL, interleukin; MMP, matrix metalloproteinase; PEP, prolyl endopeptidase; TCR, T-cell receptor; TG2, tiss
Potential role of phospholipase D2 in increasing interleukin-2 production by T-lymphocytes through activation of mitogen-activated protein kinases ERK1/ERK2
Keywords: TCR، گیرنده سلول T; PLD2, phospholipase D2; PA, phosphatidic acid; DAG, diacylglycerol; PC, phosphatidylcholine; TCR, T-cell receptor; IL-2, interleukin-2; MAPK, mitogen-activated protein kinase; ERK, extracellular signal-regulated kinase; LFA-1, lymphocyte function-associat
A patient with clinicopathologic features of small plaque parapsoriasis presenting later with plaque-stage mycosis fungoides: Report of a case and comparative retrospective study of 27 cases of “nonprogressive” small plaque parapsoriasis
Keywords: TCR، گیرنده سلول T; HE, hematoxylin-eosin; MF, mycosis fungoides; SPP, small plaque parapsoriasis; TCR, T-cell receptor
Structural Basis for the Interaction between Focal Adhesion Kinase and CD4
Keywords: TCR، گیرنده سلول T; FAK, focal adhesion kinase; HIV, human immunodeficiency virus; FAT, focal adhesion targeting; FA, focal adhesion; PYK2, proline-rich tyrosine kinase 2; TCR, T-cell receptor; ITC, isothermal titration calorimtery; PDB, Protein Data Bank; mAb, monoclonal an
Direct Presentation of Antigen by Lymph Node Stromal Cells Protects Against CD8 T-Cell-Mediated Intestinal Autoimmunity
Keywords: TCR، گیرنده سلول T; BM, bone marrow; DTg, double transgenic; EGC, enteric glial cell; GFAP, glial fibrillary acidic protein; HA, hemagglutinin; LN, lymph node; MHC, major histocompatibility complex; MLN, mesenteric lymph node; STg, single transgenic; TCR, T-cell receptor
Toward an atomistic understanding of the immune synapse: Large-scale molecular dynamics simulation of a membrane-embedded TCR–pMHC–CD4 complex
Keywords: TCR، گیرنده سلول T; IS, immunological synapse; MD, molecular dynamics; TCR, T-cell receptor; MHC, major histocompatibility complex; pMHC, peptide-major histocompatibility complex; pMHCII, peptide-major histocompatibility complex class II; APC, antigen-presenting cell; PDB, p
Transplantation Immunology: What the Clinician Needs to Know for Immunotherapy
Keywords: TCR، گیرنده سلول T; APC, antigen-presenting cell; CNI, calcineurin inhibitor; CTLA-4, cytotoxic T lymphocyte–associated antigen 4; DC, dendritic cell; IL, interleukin; MHC, major histocompatibility complex; NK, natural killer; PD-1, programmed death-1; TCR, T-cell receptor;
Structural and Functional Evidence that Nck Interaction with CD3ε Regulates T-Cell Receptor Activity
Keywords: TCR، گیرنده سلول T; TCR, T-cell receptor; ITAM, immune tyrosine activation motif; MHC, major histocompatibility complex; APC, antigen-presenting cell; pMHC, peptide/MHC; PRS, proline-rich sequence; WT, wild type; sc, single chain; LN, lymph node; GFP, green fluorescent prote
Decreased ER-associated degradation of α-TCR induced by Grp78 depletion with the SubAB cytotoxin
Keywords: TCR، گیرنده سلول T; CHX, cycloheximide; ER, endoplasmic reticulum; ERAD, ER-associated degradation; HUS, hemolytic-uremic syndrome; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; TCR, T-cell receptor; UFD, ubiquitin-fusion degradation; UPS, ubiquitin–prot
Expansion of Pulmonary CD8+CD56+ Natural Killer T-Cells in Hypersensitivity Pneumonitis
Keywords: TCR، گیرنده سلول T; interstitial lung diseases; hypersensitivity pneumonitis; natural killer T cellsBALF, BAL fluid; IFN, interferon; ILD, interstitial lung disease; NK, natural killer; NKT, natural killer T; TCR, T-cell receptor; Th1, T-helper type 1
Modulation of T-cell signalling by non-esterified fatty acids
Keywords: TCR، گیرنده سلول T; PUFAs, polyunsaturated fatty acids; HI, heparin+intralipid; NEFA, non-esterified fatty acids; TCR, T-cell receptor; LAT, linker for activated T cells; PLCγ1, phospholipase C-gamma1; MBCD, methyl-beta-cyclodextrin; TNF, tumour necrosis factor; IL-6, interl
Immunohistochemical staining for CD45R isoforms in paraffin sections to diagnose mycosis fungoides–type cutaneous T-cell lymphoma
Keywords: TCR، گیرنده سلول T; CTCL, cutaneous T-cell lymphoma; MF, mycosis fungoides; PCR-DGGE, polymerase chain reaction denaturing gradient gel electrophoresis; TCR, T-cell receptor
Particular genetic variants of ligands for natural killer cell receptors may contribute to the HLA associated risk of primary sclerosing cholangitis
Keywords: TCR، گیرنده سلول T; PSC, primary sclerosing cholangitis; KIR, killer immunoglobulin-like receptor; HLA, human leukocyte antigen; TCR, T-cell receptor; NK cells, natural killer cells; MICA/MICB, major histocompatibility complex class I chain-related A/BPrimary sclerosing chol