
Human syndromes of immunodeficiency and dysregulation are characterized by distinct defects in T-cell receptor repertoire development
Keywords: T-cell receptor; recombination activating gene; Omenn syndrome; T-cell receptor sequencing; CDR3; Complementarity-determining region 3; IL2RG; IL-2 receptor γ; OS; Omenn syndrome; RAG; Recombination activating gene; SCID; Severe combined immunodeficiency