Keywords: IPG, immobilized pH gradient strips; TFA, trifluoro acetic acid; KNG-1, kininogen-1; HMWK, high molecular weight kininogen; LMWK, low molecular weight kininogen; MET RTK, MET receptor tyrosine kinase; ASD, autism spectrum disorder; PLAUR, urokinase plasmi
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Synchrotron μ-FTIR highlights amyloid-β conformational changes under the effect of surface wettability and external agents
Keywords: AChE, acetylcholinesterase; NS, nanostructured; Aβ, amyloid beta; TFA, trifluoro acetic acid; DMSO, dimethyl sulfoxide; μFTIR, micro Fourier transform infrared spectroscopyβ-amyloid peptide; Surface wettability; Conformational changes; Synchrotron radiati
Designed low amphipathic peptides with α-helical propensity exhibiting antimicrobial activity via a lipid domain formation mechanism
Keywords: TFA, trifluoro acetic acid; HPLC, high performance liquid chromatography; POPC, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine; POPG, 1-palmitoyl-2-oleoyl-sn-glycero-3-[phospho-rac-(1-glycerol)]; DMPC, 1,2-dimyristoyl-sn-glycero-3-phosphocholine; DMPG,
A novel toxin from the venom of the scorpion Tityus trivittatus, is the first member of a new α-KTX subfamily
Keywords: KTx, K+ channel toxin; hERG, human ether-a-go-go related gene; HPLC, high performance liquid chromatography; TFA, trifluoro acetic acid; Kv, voltage-gated K+ channel; IKCa1, Ca2+-activated K+ channelsTityus trivittatus; α-KTx20.1; Voltage-gated K+ channel
The first potassium channel toxin from the venom of the Iranian scorpion Odonthobuthus doriae
Keywords: ESI-Q-TOF MSMS, electrospray ionization hybrid quadrupole time of flight tandem mass spectrometry; HPLC, high performance liquid chromatography; KTx, K+ channel toxin; Kv, voltage-gated K+ channel; TFA, trifluoro acetic acid; 4-AP, 4-aminopyridineα-KTx 8.
OD1, the first toxin isolated from the venom of the scorpion Odonthobuthus doriae active on voltage-gated Na+ channels
Keywords: DTT, dithiothreitol; MS, mass spectrometry; RP-HPLC, reversed-phase high performance liquid chromatography; TEVC, two-electrode voltage clamp; TFA, trifluoro acetic acid; VGSC(s), voltage-gated Na+ channel(s)Iranian scorpion Odonthobuthus doriae; α-like t