Apple polyphenols suppress antigen presentation of ovalbumin by THP-1-derived dendritic cells
Keywords: Antigen presentation; Dendritic cells; THP-1; Polyphenol; Procyanidin;
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Anticancer activity of chemically prepared shrimp low molecular weight chitin evaluation with the human monocyte leukaemia cell line, THP-1
Keywords: CHI3L1; chitinase 3-like 1; 13C NMR; 13carbon nuclear magnetic resonance; DNA; desoxyribonucleotid; FBS; foetal bovine serum; FPLC; fast performance liquid chromatography; FT-I; Fourier transform infrared; HC gp-39; human cartilage glycoprotein 39; HL-60
Endogenous aggregates of amyloidogenic cystatin C variant are removed by THP-1 cells in vitro and induce differentiation and a proinflammatory response
Keywords: Cystatin C; Amyloid; THP-1; Cerebral Amyloid Angiopathy; Alzheimer's disease;
Aloe vera downregulates LPS-induced inflammatory cytokine production and expression of NLRP3 inflammasome in human macrophages
Keywords: ATP; adenosine-5â²-triphosphate; ASC; apoptosis-associated speck-like protein containing a caspase recruitment domain; ELISA; enzyme-linked immunosorbent assay; ERK; extracellular-signal-regulated kinase; GM-CSF; granulocyte-macrophage colony stimulating
Season linked responses to fine and quasi-ultrafine Milan PM in cultured cells
Keywords: PM; A549; THP-1; ROS; DNA damage;
Antibodies enhance the infection of phorbol-ester-differentiated human monocyte-like cells with coxsackievirus B4
Keywords: THP-1; Monocyte; Coxsackievirus B4; Alpha interferon; infection;
Evaluation of selected biomarkers for the detection of chemical sensitization in human skin: A comparative study applying THP-1, MUTZ-3 and primary dendritic cells in culture
Keywords: Dendritic cell; Sensitization assay; Biomarker; Contact allergy; PD-L1; DCIR; NAP-2; IL-16; MIP-1α; THP-1; MUTZ-3;
BaeR protein from Salmonella enterica serovar Paratyphi A induces inflammatory response in murine and human cell lines
Keywords: BaeR; Cytokines; Nitric oxide; RAW 264.7 cells; Salmonella enterica Paratyphi A; THP-1
Stem-bark of Terminalia arjuna attenuates human monocytic (THP-1) and aortic endothelial cell activation
Keywords: AE; alcohol extract; Butylated hydroxytoluene; (BHT); H2DCFDA; 2´,7´-dichlorofluorescin diacetate; HAECs; Human aortic endothelial cells; 3-hydroxy-3-methylglutaryl coenzyme A; HMG-CoA reductase; ICAM-1; Intercellular adhesion molecule-1; IL-8; Interleu
Anti-inflammatory activity of Mitraphylline isolated from Uncaria tomentosa bark
Keywords: IL; Interleukin; LPS; Lipopolysaccharide; THP-1; monocytic cells (ATCC TIB-202); TNF; tumor necrosis factor; XTT; sodium 3â²-[1-(phenylaminocarbonyl)-3,4-tetrazolium]-bis(4-methoxy-6-nitro) benzene sulfonic acid hydrate.; Inflammation; Uncaria tomentosa;
CD44 activation enhances acute monoblastic leukemia cell survival via Mcl-1 upregulation
Keywords: CD44; AML; Survival; Mcl-1; THP-1; Acute monoblastic leukemia; Apoptosis resistance;
Peripheral human γδ T cells control growth of both avirulent and highly virulent strains of Francisella tularensis in vitro
Keywords: Francisella tularensis; Human γδ T cells; In vitro; THP-1; IFN-γ
SIRT1 inactivation induces inflammation through the dysregulation of autophagy in human THP-1 cells
Keywords: SIRT1; Sirtinol; Autophagy; Inflammation; mTOR; THP-1
In vivo hydroquinone exposure impairs MCP-1 secretion and monocyte recruitment into the inflamed lung
Keywords: LPS; Tracheal tissue; Alveolar macrophage; Chemotaxis; THP-1; Environmental pollution;
Porphyromonas gingivalis lipopolysaccharide induces miR-146a without altering the production of inflammatory cytokines
Keywords: miR-146a; Porphyromonas gingivalis; LPS; THP-1;
Combining the observation of cell morphology with the evaluation of key inflammatory mediators to assess the anti-inflammatory effects of geranyl flavonoid derivatives in breadfruit
Keywords: AC-1; 6-geranyl-7,4â²-dihydroxyflavanone; AC-2; 4,2â²,4â²-trihydroxy-3â²-[6-hydroxy-3,7-dimethyl-2(E),7-octadienyl]chalcone; AC-3; 3,4,2â²,4â²-tetrahydroxy-3â²-geranyldihydrochalcone; AC-4; 4,2â²,4â²-trihydroxy-5â²-geranyldihydrochalcone; THP-1;
Inhibition of the transcription factor c-Jun by the MAPK family, and not the NF-κB pathway, suggests that peanut extract has anti-inflammatory properties
Keywords: Lipopolysaccharide; THP-1; NF-κB; Tumor necrosis factor-α; Tumor necrosis factor-α converting enzyme
Efficacy of tetracycline encapsulated O-carboxymethyl chitosan nanoparticles against intracellular infections of Staphylococcus aureus
Keywords: Nps; nanoparticles; O-CMC; o-carboxymethyl chitosan; Tet; tetracycline; Tet-O-CMC Nps; tetracycline loaded-O-carboxymethyl chitosan nanoparticles; Rod123; Rhodamine-123; WGA-AF; wheat germ agglutinin-Alexa fluor; SA113; Staphylococcus aureus 113 (specific
TGF-β inhibits the uptake of modified low density lipoprotein by human macrophages through a Smad-dependent pathway: A dominant role for Smad-2
Keywords: AcLDL; acetylated low density lipoprotein; ABCA-1; ATP-binding cassette transporter A-1; ABCG-1; ATP-binding cassette transporter G-1; ApoE; apolipoprotein E; ApoEâ/â; apolipoprotein E deficient; CD36; cluster of differentiation 36; DiI; 1,1â²-diocta
Formulation of oryzalin (ORZ) liposomes: In vitro studies and in vivo fate
Keywords: CL; cutaneous leishmaniasis; MCL; mucocutaneous leishmaniasis; VL; visceral leishmaniasis; TFL; Trifluralin; ORZ; Oryzalin; DPPC; Dipalmitoylphosphatidylcholine; DPPG; Dipalmitoylphosphatidylglycerol; DMPC; Dimyristoylphosphatidylcholinel; DMPG; Dimyristo
Copy number variation of CCL3L1 influences asthma risk by modulating IL-10 expression
Keywords: Asthma; Chemokine ligand 3-like 1; Copy number variation; Immunoglobulin E; Interleukin-10; THP-1;
Tamm-Horsfall protein 1 macrophage lipid accumulation unaffected by fatty acid double-bond geometric or positional configuration
Keywords: BSA; bovine serum albumin; CE; cholesteryl ester; EC; esterified cholesterol; FBS; fetal bovine serum; FC; free cholesterol; LDL; low-density lipoprotein; PUFA; polyunsaturated fatty acids; TC; total cholesterol; TG; triglycerides; THP-1; Tamm-Horsfall pr
2-Hydroxy-3-methylanthraquinone from Hedyotis diffusa WILLD Induces Apoptosis via Alteration of Fas/FasL and Activation of Caspase-8 in Human Leukemic THP-1 Cells
Keywords: 2-hydroxy-3-methylanthraquinone; Hedyotis diffusa WILLD; THP-1; Apoptosis; Fas; FasL
Cilostazol inhibits matrix invasion and modulates the gene expressions of MMP-9 and TIMP-1 in PMA-differentiated THP-1 cells
Keywords: Cilostazol; Atherosclerosis; THP-1; Invasion; MMP-9; TIMP-1;
Lipoxin A4 and its analog suppress hepatocellular carcinoma via remodeling tumor microenvironment
Keywords: BSA; bovine serum albumin; ACM; activated macrophage-conditioned media; CCM; control macrophage-conditioned media; DMSO; dimethyl sulfoxide; ECL; enhanced chemiluminescence; ELISA; enzyme-linked immunosorbent assay; FBS; fetal bovine serum; HepG2; human h
Ubiquitous hazardous metal lead induces TNF-α in human phagocytic THP-1 cells: Primary role of ERK 1/2
Keywords: Pb; THP-1; TNF-α; MAPKs; Immunotoxicity;
Nitroglycerin alters matrix remodeling proteins in THP-1 human macrophages and plasma metalloproteinase activity in rats
Keywords: Nitroglycerin; Matrix metalloproteinase-9; Extracellular matrix; Tissue inhibitor of metalloproteinase-1; THP-1; Nuclear factor-κB
Divergent cytokine responses of macrophages to Mycobacterium avium subsp. paratuberculosis strains of Types II and III in a standardized in vitro model
Keywords: Mycobacterium avium subsp. paratuberculosis; MAP-genotypes; Cytokines; THP-1; Quantitative real-time PCR
Flow cytometric screening for anti-leishmanials in a human macrophage cell line
Keywords: Leishmania amazonensis; Parasite; Amastigote; Drug screening; THP-1; Flow cytometry
Effect of chickpea protein hydrolysates on cell proliferation and in vitro bioavailability
Keywords: Chickpea; Protein hydrolysates; Bioactive peptides; Cell proliferation; THP-1; Caco-2; In vitro bioavailability; Healthy foods
Terbinafine stimulates the pro-inflammatory responses in human monocytic THP-1 cells through an ERK signaling pathway
Keywords: Terbinafine; Butenafine; THP-1; Drug-induced liver injury
Prediction of the contact sensitizing potential of chemicals using analysis of gene expression changes in human THP-1 monocytes
Keywords: Skin sensitizers; THP-1; In vitro; Gene expression
Scavenger receptor A1 is required for sensing HCMV by endosomal TLR-3/-9 in monocytic THP-1 cells
Keywords: HCMV; THP-1; SR-A1; TLR-2/-3/-9; TNF-α; IFN-β; IL-12p35
Pro-inflammatory responses in human monocytes are β1-adrenergic receptor subtype dependent
Keywords: ARs; adrenergic receptors; Bmax; maximal specific binding of radioligand; CGP 20712A; [1-(2-((3-carbamoyl-4-hydroxy)phenoxy)ethylamino)-3-(4-(1-methyl-4-trifluoromethyl-2-imidazoylyl)phenoxy)-2-propanol methanesulfonate, 2-hydroxy-5-(2-(hydroxy-3-(4-((1-m
Leishmania (Viannia) peruviana (MHOM/PE/LCA08): Comparison of THP-1 cell and murine macrophage susceptibility to axenic amastigotes for the screening of leishmanicidal compounds
Keywords: THP-1; Murine macrophages; Leishmania; Leishmania peruviana; Leishmanicidal; Amphotericin B
Metformin restores impaired HDL-mediated cholesterol efflux due to glycation
Keywords: Cholesterol efflux; HDL; Glycation; Metformin; 3-Deoxyglucosone; ABCG1; THP-1
The p38 pathway inhibitor SB202190 activates MEK/MAPK to stimulate the growth of leukemia cells
Keywords: SB202190; Leukemia; p38; ERK; Cell growth; THP-1; MV4-11
Î9-Tetrahydrocannabinol and cannabidiol modulate mitogen-induced tryptophan degradation and neopterin formation in peripheral blood mononuclear cells in vitro
Keywords: Î9-Tetrahydrocannabinol; Cannabidiol; PBMC; THP-1; Indoleamine-2,3-dioxygenase; Neopterin;
Progress on the development of human in vitro dendritic cell based assays for assessment of the sensitizing potential of a compound
Keywords: Animal alternative; U-937; THP-1; MUTZ-3; Monocyte derived dendritic cell; CD34+ derived dendritic cell; Test; Research; Validation; Biomarker; Allergen; Irritant; EU Directive 76/768/EEC; Sensitizer; Non-sensitizer
Ligand-induced Flt3-downregulation modulates cell death associated proteins and enhances chemosensitivity to idarubicin in THP-1 acute myeloid leukemia cells
Keywords: Flt3; AML; SILAC; THP-1; Chemotherapy; Apoptosis
Evaluation of photoallergic potential of chemicals using THP-1 cells
Keywords: Photoallergy; Photohapten; Prohapten; THP-1;
Pyrazinoindolone inhibitors of MAPKAP-K2
Keywords: MAPKAP-K2; THP-1
Leukotriene C4 synthase promoter driven expression of GFP reveals cell specificity
Keywords: Leukotriene; Leukotriene C4 synthase; Expression; GFP; TPA; Promoter; Retinoic acid; DMSO; AP-2; activating protein 2; C/EBP; CCAAT/enhancer binding protein; eGFP; enhanced green fluorescent protein; HEK293/T; human embryonic kidney 293T cell line; HL-60;
Effects of an anti-oxidative ACAT inhibitor on apoptosis/necrosis and cholesterol accumulation under oxidative stress in THP-1 cell-derived foam cells
Keywords: Foam cell; Apoptosis; Necrosis; ACAT inhibitor; Oxidative stress; Cholesterol; THP-1;
Regulation of the class II and class I MHC pathways in human THP-1 monocytic cells by interleukin-27
Keywords: IL-27; MHC; CIITA; IRF-1; THP-1
Novel leads from Heliotropium ovalifolium, 4,7,8-trimethoxy-naphthalene-2-carboxylic acid and 6-hydroxy-5,7-dimethoxy-naphthalene-2-carbaldehyde show specific IL-6 inhibitory activity in THP-1 cells and primary human monocytes
Keywords: Il-6; Heliotropium ovalifolium; THP-1; Human monocytes; Inflammatory disorders;
ADMA induces monocyte adhesion via activation of chemokine receptors in cultured THP-1 cells
Keywords: ACEI; angiotensin-converting enzyme inhibitor; ADMA; asymmetric dimethylarginine; Ang II; angiotensin II; ARB; angiotensin receptor blocker; AS; atherosclerosis; DDAH; dimethylarginine dimethylaminohydrolase; HPLC; high performance liquid chromatography;
Toxoplasma gondii triggers secretion of interleukin-12 but low level of interleukin-10 from the THP-1 human monocytic cell line
Keywords: Interleukin-12; Interleukin-10; Toxoplasma gondii; THP-1; Human
Long-term treatment with theophylline reduces neutrophils, interleukin-8 and tumor necrosis factor-α in the sputum of patients with chronic obstructive pulmonary disease
Keywords: Theophylline; COPD; IL-8; TNF-α; THP-1; LPS; NeutrophilsCOPD, chronic obstructive pulmonary disease; FEV, forced expiratory volume; FVC, forced vital capacity; HDAC, histone deacetylase; IL, interleukin; LPS, lipopolysaccharide; TNF, tumor necrosis factor
Differential effects of Chlamydia pneumoniae infection on cytokine levels in human T lymphocyte- and monocyte-derived cell cultures
Keywords: Chlamydia pneumoniae; Th1/Th2 cytokines; MOLT-4; THP-1