Keywords: PTM; post-translational modification; RBR; RING-between-RING; DUB; deubiquitinase; USP; ubiquitin-specific protease; SCF; Skp1-Cullin-F-box; CaMKII; Ca2Â +/calmodulin-dependent kinase 2; Cbl; Casitas B-lineage lymphoma; TKB; tyrosine kinase binding; RTK;
مقالات ISI (ترجمه نشده)
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Two Libyan siblings with beta-ketothiolase deficiency: A case report and review of literature
Keywords: 2MAA; 2-methylacetoacetate; 2M3HB; 2-methyl-3-hydroxybutyrate; MS/MS; tandem mass spectrometry; SCOT; succinyl-CoA:3-oxoacid CoA transferase; T2; mitochondrial acetoacetyl-CoA thiolase; TIG; tiglylglycine; TKB; total ketone body; T2 deficiency; ACAT1; Mut
Targeting of the MET receptor tyrosine kinase by small molecule inhibitors leads to MET accumulation by impairing the receptor downregulation
Keywords: RTK; receptor tyrosine kinase; TKI; tyrosine kinase inhibitor; HGF; hepatocyte growth factor; wt; wild type; TKB; tyrosine kinase binding; MET; Small molecule tyrosine kinase inhibitor; Receptor downregulation; CBL; Receptor ubiquitination; MET Tyr1003;
An adjacent arginine, and the phosphorylated tyrosine in the c-Met receptor target sequence, dictates the orientation of c-Cbl binding
Keywords: TKB; tyrosine kinase binding; SH2; Src homology 2; SPR; surface plasmon resonance; EGFR; epidermal growth factor receptor; Met; hepatocyte growth factor receptor; Cbl; casitas B-lineage lymphoma; c-Casitas B-lineage lymphoma tyrosine kinase binding domain
The Cbl RING finger C-terminal flank controls epidermal growth factor receptor fate downstream of receptor ubiquitination
Keywords: EGF-R; epidermal growth factor receptor; HEK; human embryonic kidney; TKB; tyrosine kinase-binding; RF; RING finger; Ubc; ubiquitin-conjugating enzyme; E2; E2/ubiquitin-conjugating enzyme; RTK; receptor tyrosine kinase; EGF; epidermal growth factor; SH2;
The multidomain protooncogenic protein c-Cbl binds to tubulin and stabilizes microtubules
Keywords: DSP; Dithiobis[succinimidylpropionate]; GST; glutathione-S-transferase; HPAEC; Human pulmonary artery endothelial cells; MAP; Microtubule-associated proteins; PTK; protein tyrosine kinase; TKB; tyrosine kinase-binding domain; c-Cbl; Tubulin; Microtubules;