MyDths and un-TOLLed truths: Sensor, instructive and effector immunity to tuberculosis
Keywords: تی‌ال‌آر; Mycobacterium tuberculosis; Macrophage; Toll-like receptor; MyD88
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Toll-like receptor 2 plays a critical role in the progression of atherosclerosis that is independent of dietary lipids
Keywords: تی‌ال‌آر; Atherosclerosis; Toll-like receptor; Inflammation; Macrophages
Extended exposure of lipopolysaccharide fraction from Porphyromonas gingivalis facilitates mononuclear cell adhesion to vascular endothelium via Toll-like receptor-2 dependent mechanism
Keywords: تی‌ال‌آر; LPS fraction; Inflammation; Adhesion molecules; Toll-like receptor
TLR2-mediated cell stimulation in bacterial vaginosis
Keywords: تی‌ال‌آر; Bacterial vaginosis; Toll-like receptor; HIV LTR; Vaginal flora; Pelvic inflammatory disease; Macrophage
Importance of myeloid differentiation factor 88 in innate and acquired immune protection against genital herpes infection in mice
Keywords: تی‌ال‌آر; MyD88; Toll-like receptor; HSV-2; Genital herpes; Female genital tract immunity
Role of Toll-like receptor 2 in innate resistance to Group B Streptococcus
Keywords: تی‌ال‌آر; Streptococcus agalactiae; Toll-like receptor 2; Penicillin-binding protein 1a; GBS; Group B Streptococcus; PBP; penicillin-binding protein; PG; peptidoglycan; WT; wild-type; TLR; toll-like receptor; TNF; tumor necrosis factor; IL-6; interleukin-6; AMP; an
Innate immunomodulatory effects of cereal grains through induction of IL-10
Keywords: تی‌ال‌آر; Rice; wheat; cereal grains; food; IL-10; immunomodulation; lipopolysaccharide; Con A; Concanavalin A; DSS; Dextran sulfate sodium; FITC; Fluorescein isothiocyanate; HDM; House dust mite; PE; Phycoerythrin; TLR; Toll-like receptor;
Mucosal macrophages and the regulation of immune responses in the intestine
Keywords: تی‌ال‌آر; Intestine; Macrophage; Toll-like receptor; Immunoregulation
Immune pathogenesis of Mixed Connective Tissue Disease: A short analytical review
Keywords: تی‌ال‌آر; Autoimmune; Mixed Connective Tissue Disease; Systemic lupus erythematosus; T cell; Autoantibody; Antigen; Ribonucleoprotein; Apoptosis; Pathogenesis; Toll-like receptor
A Toll receptor in shrimp
Keywords: تی‌ال‌آر; Toll-like receptor; Shrimp; Innate immunity; Toll/interleukin-1 receptor
Functional characterization of chicken TLR5 reveals species-specific recognition of flagellin
Keywords: تی‌ال‌آر; Toll-like receptor; Evolution; Chicken; Flagellin; NF-κB
Tollip, a negative regulator of TLR-signalling, is encoded by twin genes in salmonid fish
Keywords: تی‌ال‌آر; Rainbow trout; Atlantic salmon; Innate immunity; Gene duplication; Tollip; Toll-like receptor; VHSVAA, amino acid; EST, expressed sequence tag; IRAK, interleukin receptor associated kinase; MyD88, myeloid differentiation factor 88; nt, nucleotide; ORF, op
A Toll receptor from Chinese shrimp Fenneropenaeus chinensis is responsive to Vibrio anguillarum infection
Keywords: تی‌ال‌آر; Toll-like receptor; Shrimp; Vibrio anguillarum; WSSV; Innate immunity; Real-time PCR
Inhibition of IL-1β transcription by peptides derived from the hCMV IE2 transactivator
Keywords: تی‌ال‌آر; hCMV; human cytomegalovirus; DBD; DNA-binding domain; IL1B; gene encoding IL-1β; TLR; Toll-like receptor; bZIP; basic leucine zipper domain; Interleukin 1β; Cytomegalovirus; IE2; Transcription factors; Peptide inhibitor;
Neonatal goats display a stronger TH1-type cytokine response to TLR ligands than adults
Keywords: تی‌ال‌آر; Neonate; Toll-like receptor; Cytokine; Goat; Small ruminant; Innate immunityTLR, toll-like receptor; MLN, mesenteric lymph node; CpG-ODN, CpG oligodeoxynucleotide; FBS, fetal bovine serum; Poly I:C, polyinosinic–polycytidylic acid; PBS, phosphate-buffered
Macrophage-activating lipopeptide-2 (MALP-2) induces a localized inflammatory response in rats resulting in activation of brain sites implicated in fever
Keywords: تی‌ال‌آر; Macrophage-activating lipopeptide-2; Fever; Sickness behavior; Toll-like receptor; Circumventricular organ; Cytokine
Poor allostimulatory function of liver plasmacytoid DC is associated with pro-apoptotic activity, dependent on regulatory T cells
Keywords: تی‌ال‌آر; DC; dendritic cells; Flt3L; fms-like tyrosine kinase 3 ligand; mDC; myeloid DC; pDC; plasmacytoid DC; Treg; regulatory T cells; Foxp3; forkhead winged helix protein-3; Dendritic cells; Liver; T cells; Mouse; Endotoxin; Toll-like receptor; Tolerance;
Toll-like receptor 4 and cytokine expression involved in functional immune response in an originally established porcine intestinal epitheliocyte cell line
Keywords: تی‌ال‌آر; PRRs; pattern recognition receptors; PAMPs; pathogen-associated molecular patterns; TLR; Toll-like receptor; PIE; Porcine Intestinal Epitheliocytes; LPS; Lipopolysaccharide; ETEC; Enterotoxigenic Escherichia coli; DIC; differential interference contrast;
Oral dendritic cells mediate antigen-specific tolerance by stimulating TH1 and regulatory CD4+ T cells
Keywords: تی‌ال‌آر; dendritic cell; mucosal immunity; sublingual immunotherapy; APCs; Antigen-presenting cells; BM-DC; Bone marrow-derived dendritic cell; CFSE; Carboxy-fluorescein diacetate, succinimyl ester; DC; Dendritic cell; FACS; Fluorescence-activated cell sorting;
Effective prevention and therapy of experimental allergic asthma using a GATA-3-specific DNAzyme
Keywords: تی‌ال‌آر; Allergic asthma; GATA-3; DNAzymes; TH2 cells; antisense DNA; small interference RNA; AHR; Airway hyperresponsiveness; asDNA; Antisense DNA; BAL; Bronchoalveolar lavage; BDNF; Brain-derived neurotrophic factor; FACS; Fluorescence-activated cell sorting; HE
A mouse Fcγ-Fcε protein that inhibits mast cells through activation of FcγRIIB, SH2 domain-containing inositol phosphatase 1, and SH2 domain-containing protein tyrosine phosphatases
Keywords: تی‌ال‌آر; FcγRIIB; mast cell inhibition; FcεRI signaling; BMMC; Bone marrow-derived mast cells; DNP; Dinitrophenyl; ERK; Extracellular signal-regulated kinase; hGE2; Human GE2; ITIM; Immunoreceptor tyrosine-based inhibitory motif; mGE; Mouse homolog of human GE
Innate responsiveness of CD8 memory T-cell populations nonspecifically inhibits allergic sensitization
Keywords: تی‌ال‌آر; CD8 T cell; immunologic memory; innate immunity; allergy; TH1/TH2; dendritic cell; IL-12; BAL; Bronchoalveolar lavage; CD8 Tm; CD8 memory T cell; DC; Dendritic cell; NK; Natural killer; PAMP; Pathogen-associated molecular pattern; SEB; Staphylococcal ente
The zinc finger protein and transcriptional repressor Gfi1 as a regulator of the innate immune response
Keywords: تی‌ال‌آر; Gfi1; Endotoxin; Apoptotsis; Toll-like receptor; Inflammation; Innate immune response; Cytokines
IFN regulation and functions in myeloid dendritic cells
Keywords: تی‌ال‌آر; Myeloid DC; Type I IFN; Toll-like receptor; Gene regulation; Immunoregulation
Gastrointestinal nematode challenge induces some conserved gene expression changes in the gut mucosa of genetically resistant sheep
Keywords: تی‌ال‌آر; Ovine; Sheep; Nematode; Toll-like receptor; Reactive oxygen; Inflammatory response; Resistant;
Application of six-color flow cytometry for the assessment of dendritic cell responses in whole blood assays
Keywords: تی‌ال‌آر; PBDC; peripheral blood dendritic cell; WB; whole blood; TLR; toll-like receptor; mDC; myeloid DC; pDC; plasmacytoid DC; TNF; tumor-necrosis factor; IFN; interferon; PBMCs; peripheral blood mononuclear cells; poly(I:C); polyribosinoinic-polyribocytidylic
Influenza-induced expression of functional tumor necrosis factor-related apoptosis-inducing ligand on human peripheral blood mononuclear cells
Keywords: تی‌ال‌آر; TRAIL; Influenza; ssRNA; Toll-like receptor
Innate microbial sensors and their relevance to allergy
Keywords: تی‌ال‌آر; Innate; immunity; receptor; microbial recognition; Toll-like receptor; PAMP; PRR; CLR; NOD-like receptor; antimicrobial peptide; allergy; asthma; hygiene hypothesisAD, Atopic dermatitis; APC, Antigen-presenting cell; CLR, C-type lectin receptor; CRP, C-re
Corticosteroid-resistant asthma is associated with classical antimicrobial activation of airway macrophages
Keywords: تی‌ال‌آر; Corticosteroids; asthma; resistance; genes; endotoxin; BAL; Bronchoalveolar lavage; CR; Corticosteroid resistant; CS; Corticosteroid sensitive; LAL; Limulus amebocyte lysate; TLR; Toll-like receptor;
Analysis of innate immune signal transduction with autocatalytic expression vectors
Keywords: تی‌ال‌آر; IL-1; interleukin-1; IL8; interleukin-8; TLR; toll-like receptor; IL-1RI; type 1 interleukin-1 receptor; TIR; Toll/interleukin-1 receptor; miR; micro-ribonucleic acid; LPS; lipopolysaccharide: NF-κB, Nuclear Factor kappa B(see also RelA); RelA; reticuloe
Human immature myeloid dendritic cells trigger a TH2-polarizing program via Jagged-1/Notch interaction
Keywords: تی‌ال‌آر; Dendritic cells; TH1; TH2; Toll-like receptors; Notch; Jagged-1; Delta-4; STAT-4; STAT-6; IL-4; IL-12; BDCA; Blood dendritic cell antigen; DAPT; N(N-[3,5-difluorophenacetyl-L-alanyl])-S-phenylglycine t-butyl ester; DC; Dendritic cell; iDC; Immature dendri
Toll-Like Receptor 5 Engagement Modulates Tumor Development and Growth in a Mouse Xenograft Model of Human Colon Cancer
Keywords: تی‌ال‌آر; ENA-78; epithelial cell-derived neutrophil-activating peptide-78; MCP-1; monocyte chemoattractant protein-1; MIP3α; macrophage-inflammatory protein α; MyD88; myeloid differentiation factor 88; NAP-2; neutrophil-activating peptide 2; PECAM; platelet/endo
Presymptomatic differences in Toll-like receptor function in infants who have allergy
Keywords: تی‌ال‌آر; Toll-like receptors; hygiene hypothesis; cord blood; allergic disease; cytokines; endotoxin; APC; Antigen-presenting cell; mDC; Myeloid dendritic cell; MFI; Mean fluorescence intensity; MxA; Myxovirus resistance protein A; NK; Natural killer; pDC; Plasmac
Animal shed Bacillus licheniformis spores possess allergy-protective as well as inflammatory properties
Keywords: تی‌ال‌آر; Allergy protection; animal shed dust; hygiene hypothesis; Bacillus licheniformis spores; ovalbumin mouse model; BAL; Bronchoalveolar lavage; Blspo; Bacillus licheniformis 467 spores; DC; Dendritic cell; hiBlspo; Heat-inactivated Bacillus licheniformis 467
Neuro-immune interactions in inflammatory bowel disease and irritable bowel syndrome: Future therapeutic targets
Keywords: تی‌ال‌آر; Inflammatory bowel disease; Irritable bowel syndrome; Neuro-immune interaction; NANC nerve; Cytokine; Chemokine; Toll-like receptor; Immunoglobulin
Disruption of T-cell immunoglobulin and mucin domain molecule (TIM)-1/TIM4 interaction as a therapeutic strategy in a dendritic cell-induced peanut allergy model
Keywords: تی‌ال‌آر; Intestine; peanut allergy; TH cell; dendritic cell; bacteria; BMDC; Bone marrow-derived dendritic cell; CFSE; Carboxyfluorescein diacetate succinimidyl ester; C-mice; Mice in which bone marrow-derived dendritic cells were stimulated with cholera toxin alo
Do all of the neurologic diseases in patients with DNA repair gene mutations result from the accumulation of DNA damage?
Keywords: تی‌ال‌آر; Aicardi–Goutières syndrome; Cockayne syndrome; Oligodendrocytes; Myelin; Calcification; Vascular disease; Thyroid hormone; TREX1; RNASEH2; Toll-like receptor; Innate immune system
Receptor mosaics of neural and immune communication: Possible implications for basal ganglia functions
Keywords: تی‌ال‌آر; Ab; amyloid-beta protein; ABGA; antibasal ganglia antibody; AD; Alzheimer's disease; AGE; advanced glycation endproducts; AIDS; acquired immunodeficiency syndrome; ALS; amyotrophic lateral sclerosis; CA; cornu ammonis; CB; cannabinoid; CD; cluster designa
Bovine viral diarrhea viruses modulate toll-like receptors, cytokines and co-stimulatory molecules genes expression in bovine peripheral blood monocytes
Keywords: تی‌ال‌آر; Monocytes; Toll-like receptor; Interferon de Type I; Cytokine Pro-inflammatoire; BVDV; Th1/Th2Monocytes; Toll-like receptor; Type I IFN; Pro-inflammatory cytokine; BVDV; Th1/Th2
A Transient Breach in the Epithelial Barrier Leads to Regulatory T-Cell Generation and Resistance to Experimental Colitis
Keywords: تی‌ال‌آر; DC; dendritic cell; IFN; interferon; IL; interleukin; LAP; latency-associated peptide; LP; lamina propria; LPMC; lamina propria mononuclear cell; siRNA; small interfering RNA; TGF; transforming growth factor; TLR; Toll-like receptor; TNBS; trinitrobenzene
Impairment of T-regulatory cells in cord blood of atopic mothers
Keywords: تی‌ال‌آر; Adaptive; cord blood; cytokines; innate; IL; regulatory T cells; TH17 cells; Toll-like receptor; CBMC; Cord blood mononuclear cell; cpm; Counts per minute; CT; Threshold cycle; CTLA4; Cytotoxic T-lymphocyte-associated protein 4; D+L; Dermatophagoides pt
Inhibition of lipid A-mediated type I interferon induction by Bactericidal/permeability-increasing protein (BPI)
Keywords: تی‌ال‌آر; Toll-like receptor; TICAM-1; Interferon-beta; Chemically synthesized lipid A;
From Tolerance to Autoimmunity: Is There a Risk in Early Life Vaccination?
Keywords: تی‌ال‌آر; vaccine; autoimmunity; Toll-like receptor; T helper cell
Study of disease-relevant polymorphisms in the TLR4 and TLR9 genes: A novel method applied to the analysis of the Portuguese population
Keywords: تی‌ال‌آر; Bi-PASA; Toll-like receptor; Polymorphism
Photoperiod alters macrophage responsiveness, but not expression of Toll-like receptors in Siberian hamsters
Keywords: تی‌ال‌آر; Photoperiod; Immunity; Seasonal; Toll-like receptor; Lipopolysaccharide; Ecoimmunology;
Toll-like receptor 9-mediated cytosolic phospholipase A2 activation regulates expression of inducible nitric oxide synthase
Keywords: تی‌ال‌آر; Toll-like receptor; Cytosolic phospholipase A2; Arachidonic acid; iNOS
Hyperthermia differentially regulates TLR4 and TLR2-mediated innate immune response
Keywords: تی‌ال‌آر; TLR, toll-like receptor; LPS, lipopolysaccharide; LTA, lipoteichoic acids; PAMP, pathogen associated molecule pattern; MAPK, mitogen-activated protein kinaseFever; Toll-like receptor; NF-κB; Macrophages; Cytokines
Toll-like receptor 2 mediates CNS injury in focal cerebral ischemia
Keywords: تی‌ال‌آر; Stroke; Focal cerebral ischemia; Toll-like receptor; Microglia
Dendritic cells in human aging
Keywords: تی‌ال‌آر; Phagocytosis; Migration; Toll-like receptor; CD4+ T
The role of indoor allergens in chronic allergic disease
Keywords: تی‌ال‌آر; Indoor allergens; asthma; atopic dermatitis; mammalian allergens; total IgE; tolerance; modified TH2 response; AD; Atopic dermatitis; TLR; Toll-like receptor;