TLR2 has a detrimental role in mouse transient focal cerebral ischemia
Keywords: تی‌ال‌آر; Cerebral ischemia; Toll-like receptor; TLR2; Stroke; MCAO; Knockout mice;
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Toll-like receptors in the uterus, cervix, and placenta: is pregnancy an immunosuppressed state?
Keywords: تی‌ال‌آر; innate immune system; pregnancy; Toll-like receptor;
Differentiation-dependent expression of interferon gamma and toll-like receptor 9 in 3T3-F442A adipocytes
Keywords: تی‌ال‌آر; Adipocyte; Differentiation; Interferon gamma; Toll-like receptor; T lymphocyte; MacrophageAT, adipose tissue; CD, cluster of differentiation; E2-PDH, E2 subunit of pyruvate dehydrogenase; ELISA, enzyme linked immunosorbent assay; GAPDH, glyceraldehyde-3-p
Innate immune function of the human decidual cell at the maternal–fetal interface
Keywords: تی‌ال‌آر; Fetal inflammatory process; Interluekin-8; Preterm birth; Term pregnancy; Toll-like receptor
Measles virus–dendritic cell interaction via SLAM inhibits innate immunity: Selective signaling through TLR4 but not other TLRs mediates suppression of IL-12 synthesis
Keywords: تی‌ال‌آر; Measles virus; Dendritic cell; SLAM; Toll-like receptor; IL-12; Immunosuppression
Signalling pathways mediating type I interferon gene expression
Keywords: تی‌ال‌آر; Virus; Interferon; Toll-like receptor; Signalling
The effects of suplatast tosilate (IPD-1151T) on innate immunity and antigen-presenting cells
Keywords: تی‌ال‌آر; Suplatast tosilate; Dendritic cells; Toll-like receptor; Antigen-presenting cells; T-helper cytokines
The role of the innate immune response in autoimmune disease
Keywords: تی‌ال‌آر; Autoimmune disease; Interferon; Innate immune system; Tolerance; Ignorance; Toll-like receptor
Toll-like receptor 2 and 4 combination engagement upregulate IL-15 synergistically in human rheumatoid synovial fibroblasts
Keywords: تی‌ال‌آر; Toll-like receptor; Inflammation; IL-15; Rheumatoid arthritis; Fibroblast-like synoviocyte
Association of Toll-like receptor–4 (Asp299Gly and Thr399Ileu) gene polymorphisms with gastritis and precancerous lesions
Keywords: تی‌ال‌آر; Innate immunity; Toll-like receptor; Polymorphism; Gastritis; Risk
Reducing the Toll of Inflammatory Lung Disease
Keywords: تی‌ال‌آر; hygiene; infection; Toll-like receptor; treatmentCpG, cytosine-guanine dinucleotide; IFN, interferon; IL, interleukin; LPS, lipopolysaccharide; MAPK, mitogen-activated protein kinase; NF, nuclear factor; Th1, T-helper type 1; Th2, T helper type 2; TLR, To
HIF-1alpha expression is associated with an atheromatous inflammatory plaque phenotype and upregulated in activated macrophages
Keywords: تی‌ال‌آر; Atherosclerosis; Inflammation; Immune system; Angiogenesis; Hypoxia; Peripheral artery disease; Macrophage; Vascular endothelial growth factor; Vulnerable plaque; Neovascularization; Microvessel; Toll-like receptor; TLR4; Peripheral vascular disease; LPS
TLR-ligand stimulated interleukin-23 subunit expression and assembly is regulated differentially in murine plasmacytoid and myeloid dendritic cells
Keywords: تی‌ال‌آر; Dendritic; Interleukin-23; Toll-like receptor; TLR; LPS; CpG; Plasmacytoid; Myeloid; Langerhans; Interleukin-12; p19; p40; Splice variant
Innate immune sensing of pathogens and danger signals by cell surface Toll-like receptors
Keywords: تی‌ال‌آر; Toll-like receptor; Innate immunity; Lipopolysaccharide; Lipopeptide; Radioprotective 105
Identification by surface plasmon resonance of the mycobacterial lipomannan and lipoarabinomannan domains involved in binding to CD14 and LPS-binding protein
Keywords: تی‌ال‌آر; LM; lipomannan; LAM; lipoarabinomannan; LBP; LPS-binding protein; MMP; matrix metalloproteinase; LPS; lipopolysaccharide; MPI; mannosyl-phosphatidyl-myo-inositol; TLR; Toll-like receptor; PIM2; phosphatidyl-myo-inositol dimannoside; PIM; phosphatidyl-myo-
Expression of toll-like receptors 2, 3, 4, and 9 genes in the human endometrium during the menstrual cycle
Keywords: تی‌ال‌آر; Toll-like receptor; Endometrium; Expression; In situ hybridization
Cell surface receptors for molecular chaperones
Keywords: تی‌ال‌آر; Extracellular; Heat shock protein; Receptor; Scavenger; Toll-like receptor; Tumor; Immunity; Signaling
Leptospirosis renal disease: Understanding the initiation by Toll-like receptors
Keywords: تی‌ال‌آر; leptospirosis; Toll-like receptor; tubulo-interstitial nephritis; interstitial fibrosis
Opposing roles of RNA receptors TLR3 and RIG-I in the inflammatory response to double-stranded RNA in a Kaposi’s sarcoma cell line
Keywords: تی‌ال‌آر; Kaposi’s sarcoma; Poly(I:C); TLR3; RIG-I; MDA5; Toll-like receptor; Pattern recognition receptor
TLR2 synergizes with both TLR4 and TLR9 for induction of the MyD88-dependent splenic cytokine and chemokine response to Streptococcus pneumoniae
Keywords: تی‌ال‌آر; Toll-like receptor; Streptococcus pneumoniae; Innate immunity; Cytokine; Chemokine; MyD88; Bacteria; Mouse; In vitro
Toll-like receptor (TLR)2 and TLR3 sensing is required for dendritic cell activation, but dispensable to control Schistosoma mansoni infection and pathology
Keywords: تی‌ال‌آر; Parasitic helminth; Rodent; Dendritic cell; Toll-like receptor; Th1/Th2 responseTLR, Toll-like receptor; DCs, dendritic cells; ISG, IFN-stimulated gene; PRR, pattern recognition receptor; WT, wild type; GARG, glucocorticoid-attenuated response gene; IP-10
Using house dust extracts to understand the immunostimulatory activities of living environments
Keywords: تی‌ال‌آر; Allergy; Dendritic cell; Endotoxin; House dust; Hygiene hypothesis; Toll-like receptor; BMDDC; Bone marrow derived dendritic cell; HDE; house dust extract; ISS; immunostimulatory sequence phosphorothioate oligodeoxynucleotide; MAMP; microbe-associated mol
Innate control of adaptive immunity: Dendritic cells and beyond
Keywords: تی‌ال‌آر; Dendritic cells; Th1; Cytotoxic T lymphocytes; Lymph node; Toll-like receptor
Staphylococcal enterotoxin B increases TIM4 expression in human dendritic cells that drives naïve CD4 T cells to differentiate into Th2 cells
Keywords: تی‌ال‌آر; T helper cell; Dendritic cell; Staphylococcal enterotoxin B; Toll-like receptor
Toll-like receptor 2 ligand mediates the upregulation of angiogenic factor, vascular endothelial growth factor and interleukin-8/CXCL8 in human rheumatoid synovial fibroblasts
Keywords: تی‌ال‌آر; Toll-like receptor; Angiogenesis; Vascular endothelial growth factor: Interleukin-8; Rheumatoid arthritis
Decreased suppression of immune stimulatory CpG motifs in plant DNA
Keywords: تی‌ال‌آر; HEL, hen-egg lysozyme; Ig-Tg, Ig transgenic; BC, Brassica Chinensis; EC, E. coli; CT, calf thymus; CpG-S, stimulatory CpG motifs; CpG-N, neutralizing CpG-containing oligomersCpG motif; Plant DNA; Immune; Suppression; Toll-like receptor
Effect of intramammary infusion of bacterial lipopolysaccharide on experimentally induced Staphylococcus aureus intramammary infection
Keywords: تی‌ال‌آر; Endotoxin; Inflammation; Lipopolysaccharide; Mastitis; Staphylococcus aureus; Toll-like receptor
Involvement of Toll-like receptors in the immune response of nasal polyp epithelial cells
Keywords: تی‌ال‌آر; Toll-like receptor; Double-stranded RNA; Peptidoglycan; Lipopolysaccharide; Epithelial cells; Chronic rhinosinusitis
A Toll-like receptor 7 single nucleotide polymorphism protects from advanced inflammation and fibrosis in male patients with chronic HCV-infection
Keywords: تی‌ال‌آر; HCV, hepatitis C virus; TLR, Toll-like receptor; SNP, single nucleotide polymorphism; HBV, hepatitis B virus; UTR, untranslated region; pDC, plasmacytoid dendritic cellHCV; Fibrosis; Toll-like receptor; Genetic polymorphism; Innate immunity
Glycomics-driven discoveries in schistosome research
Keywords: تی‌ال‌آر; Schistosoma; Glycoprotein; Carbohydrate; Host-parasite interaction; Immunomodulation; Antigen; Glycome; Glycan; Lectin; CAA; circulating anodic antigen; CCA; circulating cathodic antigen; CD; cluster of differentiation; DC; dendritic cell; DC-SIGN; dend
Molecular cloning and characterization of Toll-like receptor 9 in Japanese flounder, Paralichthys olivaceus
Keywords: تی‌ال‌آر; Innate immunity; Japanese flounder; Luciferase; Myeloid differentiation factor 88; Promoter; Reporter assay; Toll-like receptor; Tumor necrosis factor
TLR2 and TLR4 agonists synergistically up-regulate SR-A in RAW264.7 through p38
Keywords: تی‌ال‌آر; Rodent; Macrophages; Lipopolysaccharide; Class A scavenger receptor; Toll-like receptor
Parental smoking impairs vaccine responses in children with atopic genotypes
Keywords: تی‌ال‌آر; Genetics; environmental exposure; atopy; public health; smoking; toxicology; DTPa; Diphtheria-tetanus-pertussis acellular; DTPw; Diphtheria-tetanus-pertussis whole cell; ETS; Environmental tobacco smoke; IL-4Rα; IL-4 receptor α; PS; Parental smoking; SE
TLR signaling
Keywords: تی‌ال‌آر; Innate immunity; Signal transduction; Toll-like receptor
Oral resiquimod in chronic HCV infection: Safety and efficacy in 2 placebo-controlled, double-blind phase IIa studies
Keywords: تی‌ال‌آر; Resiquimod; Hepatitis C virus; Toll-like receptor; TLR7 agonist; TLR8 agonist; Clinical trial; Treatment; Pharmacokinetics; Pharmacodynamics
Molecular cloning and characterisation of the griffon vulture (Gyps fulvus) toll-like receptor 1
Keywords: تی‌ال‌آر; Toll-like receptor; Innate immunity; Vulture; CD molecules
Structural characterisation and expression analysis of Toll-like receptor 2 gene from catfish
Keywords: تی‌ال‌آر; Catfish; Fish; TLR2; Immunity; Toll-like receptor; Gene expression; Disease
Innate host defense: Nox and Duox on phox's tail
Keywords: تی‌ال‌آر; NADPH oxidase; Innate Immunity; Toll-like receptor; Dendritic cells; Reactive oxygen species
Suppression of NF-κB and AP-1 activation in monocytic cells persistently infected with measles virus
Keywords: تی‌ال‌آر; Measles virus; NF-κB; AP-1; Immunosuppression; Monocyte; Toll-like receptor; Signal transduction
Lipoteichoic acid downregulates FcεRI expression on human mast cells through Toll-like receptor 2
Keywords: تی‌ال‌آر; Mast cells; basophils; Fc receptors; allergy; β-hex; β-Hexosaminidase; ERK; Extracellular signal-regulated kinase; FITC; Fluorescein isothiocyanate; LTA; Lipoteichoic acid; MC; Mast cell; MFI; Mean fluorescence intensity; NP; Nitrophenylacetyl; ODN; O
Gut Microbiota: Mining for Therapeutic Potential
Keywords: تی‌ال‌آر; AIEC; adherent-invasive Escherichia coli; CARD; caspase recruitment domain; DC; dendritic cell; IBD; inflammatory bowel disease; IL; interleukin; IFN; interferon; MAP; Mycobacterium avium subspecies paratuberculosis; MDP; muramyl dipeptide; NF; nuclear fa
Myeloid differentiation factor 88-independent Toll-like receptor pathway: Sustaining inflammation or promoting tolerance?
Keywords: تی‌ال‌آر; Toll-like receptor; MyD88; Trif; Endotoxin tolerance;
Different roles of TiR8/Sigirr on toll-like receptor signaling in intrarenal antigen-presenting cells and tubular epithelial cells
Keywords: تی‌ال‌آر; SIGIRR; toll-like receptor; lipopolysaccharide; infection
Human rheumatoid synovial fibroblasts promote osteoclastogenic activity by activating RANKL via TLR-2 and TLR-4 activation
Keywords: تی‌ال‌آر; Toll-like receptor; Osteoclastogenesis; FLS; RANKL; Autoimmune arthritis
Administration of a dual toll-like receptor 7 and toll-like receptor 8 agonist protects against influenza in rats
Keywords: تی‌ال‌آر; Toll-like receptor; Influenza; Innate immunity; Interferon; Cytokine;
Characterization of twin toll-like receptors from rainbow trout (Oncorhynchus mykiss): Evolutionary relationship and induced expression by Aeromonas salmonicida salmonicida
Keywords: تی‌ال‌آر; Rainbow trout; Innate immunity; Gene expression; Gene duplication; Toll-like receptor; Atlantic salmon; PathogenTLR, Toll-like receptors; LRR, Leucine-rich repeat, PCR, Polymerase chain reaction; RT-PCR, PCR following reverse transcription of RNA
Divergent Toll-like receptors in catfish (Ictalurus punctatus): TLR5S, TLR20, TLR21
Keywords: تی‌ال‌آر; Catfish; Genome; TLR5; TLR20; TLR21; Toll-like receptor; Disease; Innate immunity
Ligand-induced differential cross-regulation of Toll-like receptors 2, 4 and 5 in intestinal epithelial cells
Keywords: تی‌ال‌آر; Toll-like receptor; Cross-regulation; Mucosa
Toll-Like Receptor-4 Promotes the Development of Colitis-Associated Colorectal Tumors
Keywords: تی‌ال‌آر; AOM; azoxymethane; BrdU; bromodeoxyuridine; CAC; colitis-associated cancer; Cox; cyclooxygenase; DSS; dextran sodium sulfate; EGFR; epidermal growth factor receptor; IECs; intestinal epithelial cells; LPS; lipopolysaccharide; NF-κB; nuclear factor κ B;
Adenoviral infection induces a multi-faceted innate cellular immune response that is mediated by the toll-like receptor pathway in A549 cells
Keywords: تی‌ال‌آر; Ad; Innate immune response; Microarray; Toll-like receptor