کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3391823 | 1221087 | 2007 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Innate control of adaptive immunity: Dendritic cells and beyond
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
ایمونولوژی
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چکیده انگلیسی
Innate immune recognition of pathogens triggers both immediate defenses against the invading pathogens and the initiation of adaptive immune responses. Dendritic cells (DCs) play a key role in sensing and processing microbial information and directing the differentiation of naïve lymphocytes to effector cells suitable against particular types of infections. These processes within DCs are intricately controlled at the levels of the cell, anatomical location, migration and their interaction with other cell types. This review focuses on recent understanding of the contributions of several key cell types, which regulate, and are regulated by DCs, in the generation of adaptive immune responses.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Seminars in Immunology - Volume 19, Issue 1, February 2007, Pages 48–55
Journal: Seminars in Immunology - Volume 19, Issue 1, February 2007, Pages 48–55
نویسندگان
Heung Kyu Lee, Akiko Iwasaki,