Keywords: ترانس گلوتامیناز 2; AED; antiepileptic drug; AGA; anti-gliadin antibody; EMA; endomysial antibody; HLA; human leukocyte antigen; MRI; magnetic resonance imaging; NAA/Cr; N-acetyl aspartate:creatine ratio; PHT; patients without clinical evidence of ataxia; PHTA; patients with
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Keywords: ترانس گلوتامیناز 2; DIV; days in vitro; ECM; extracellular matrix; MCAL; middle cerebral artery ligation; NES; nuclear export signal; NLS; nuclear localization signal; OGD; oxygen and glucose deprivation; scr; scrambled; TG2; transglutaminase 2; Transglutaminase; Neurons; RN
Keywords: ترانس گلوتامیناز 2; Cell survival; Hypoxia; Neuroblastoma cells; Neurite outgrowth; NGF; Transglutaminase 2;
Keywords: ترانس گلوتامیناز 2; Transglutaminase 2; Astrocytes; Neuroprotection; CNS injury;
Keywords: ترانس گلوتامیناز 2; Dopaminergic (DA) neurons; Inflammatory mediators; Mast cells; Parkinson's disease; Substantia nigra; Transglutaminase 2; BMMCs; Bone marrow-derived mast cells; DA neurons; Dopaminergic neurons; DAT; dopamine transporter; LTs; Leukotrienes; MAOB; Monoamin
Keywords: ترانس گلوتامیناز 2; ASO; antisense oligonucleotide; ECM; extracellular matrix; DDR; discoidin domain receptor; FAP; fibroblast activation protein; HSC; hepatic stellate cell(s); MF; myofibroblast(s); Lox; lysyl oxidase; Loxl; lysyl oxidase-like; MMP; matrix metalloproteinase
Keywords: ترانس گلوتامیناز 2; Transglutaminase 2; Apoptosis; Protein expression; Cisplatin; Hepatocarcinoma; Chemotherapy;
Keywords: ترانس گلوتامیناز 2; VEGF; vascular endothelial growth factor; miR; microRNA; HUVEC; human vein endothelial cells; BECN1; Beclin1; HIFs; hypoxia inducible factors; PDGFb; platelet-derived growth factor B; Endotheliocyte; microRNAs; Mitochondrial dysfunction; Oxidative stress;
Keywords: ترانس گلوتامیناز 2; Transglutaminase 2; On-chip TG2 kinase activity assay; Michaelis-Menten constants (Km); Substrate affinity map;
Keywords: ترانس گلوتامیناز 2; Monocyte-Macrophage Precursor Cells; Gastrointestinal Motility; Enteric Nervous System; Interstitial Cells of Cajal; BMP; bone morphogenetic protein; CCR2; C-C chemokine receptor type 2; CD206; mannose receptor C, Type 1 aka MRC1; CSF1; colony-stimulat
Keywords: ترانس گلوتامیناز 2; AB; Apoptotic body; ADP; Adenosine diphosphate; Anx; Annexin; ASARM; Acidic serine- and aspartate-rich motif; ATP; Adenosine triphosphate; BMP; Bone morphogenetic protein; CK; Choline kinase; CKD; Chronic kidney disease; ECM; Extracellular matrix; GPI; Gl
Keywords: ترانس گلوتامیناز 2; Bcl-2; B-cell lymphoma 2; IL-6; interleukin-6; INF-γ; interferon-γ; MGD; Meibomian gland dysfunction; MMP9; matrix metalloproteinase 9; RT PCR; real-time polymerase chain reaction; SS; Sjögren syndrome; TBUT; tear film break-up time; TG2; transglutamin
Keywords: ترانس گلوتامیناز 2; Castration-resistant prostate cancer; Inflammation; NF-κB; Transglutaminase 2; Androgen receptor;
Nicotine induces apoptosis in human osteoblasts via a novel mechanism driven by H2O2 and entailing Glyoxalase 1-dependent MG-H1 accumulation leading to TG2-mediated NF-kB desensitization: Implication for smokers-related osteoporosis
Keywords: ترانس گلوتامیناز 2; Nicotine; H2O2; Glyoxalase 1; MG-H1; AGEs; Transglutaminase 2; NF-kB;
Efferocytosis in atherosclerotic lesions: Malfunctioning regulatory pathways and control mechanisms
Keywords: ترانس گلوتامیناز 2; ABC; ATP-binding cassette; ABCA1; ATP-binding membrane cassette transporter A1; ABCG1; ATP binding cassette transporter G1; ABCA7; ATP-binding cassette transporters A7; Abs; Antibodies; ACs; Apoptotic cells; AICAR; 5-aminoimidazole-4-carboxamide-1-β-d-ri
HLA-DQ-Gluten Tetramer Blood Test Accurately Identifies Patients With and Without Celiac Disease in Absence of Gluten Consumption
Keywords: ترانس گلوتامیناز 2; CD38; Gluten-Sensitive; Gut-Homing; Noninvasive Test; β7; integrin β7; CI; confidence interval; DGP; deamidated gliadin peptide; gluten-specific T cells; HLA-DQ-gluten-tetramer+ integrin β7+ effector-memory T cells; ELISA; enzyme-linked immunosorbent
Role of transglutaminase 2 in A1 adenosine receptor- and β2-adrenoceptor-mediated pharmacological pre- and post-conditioning against hypoxia-reoxygenation-induced cell death in H9c2 cells
Keywords: ترانس گلوتامیناز 2; A1 adenosine receptor; β2-adrenoceptor; Cardiomyocytes; Transglutaminase 2; Pre-conditioning; Post-conditioning;
Inhibition or ablation of transglutaminase 2 impairs astrocyte migration
Keywords: ترانس گلوتامیناز 2; Transglutaminase 2; Astrocytes; Migration; TGFβ; Transamidation;
New insights in the pathogenesis of immunoglobulin A vasculitis (Henoch-Schönlein purpura)
Keywords: ترانس گلوتامیناز 2; ADCC; antibody-dependent cellular cytotoxicity; AECA; Anti-epithelial cell antibodies; ANCA; Anti-neutrophil cytoplasmic antibodies; β2GPI; β2-glycoprotein I; CDC; Complement-dependent cytotoxicity; EC; endothelial cell; FcαRI; Fc receptor for IgA; Gal
A B-Cell Gene Signature Correlates With the Extent of Gluten-Induced Intestinal Injury in Celiac Disease
Keywords: ترانس گلوتامیناز 2; Oral Tolerance; Mucosal Immunity; Autoimmunity; Regulatory B Cell; Cd; crypt depth; CeD; celiac disease; cRNA; complementary RNA; TG2; transglutaminase 2; TR; T-cell receptor; Vh; villus height; Vh:Cd; ratio of villus height to crypt depth;
β2-adrenoceptor-induced modulation of transglutaminase 2 transamidase activity in cardiomyoblasts
Keywords: ترانس گلوتامیناز 2; β2-adrenoceptor; Phosphorylation; Protein kinase A; ERK1/2; H9c2 cardiomyocytes; Transglutaminase 2;
Age dictates a steroid-resistant cascade of Wnt5a, transglutaminase 2, and leukotrienes in inflamed airways
Keywords: ترانس گلوتامیناز 2; Age; airway remodeling; airway inflammation; allergy; asthma; bronchial epithelial cells; house dust mite; leukotrienes; lipid mediators; nasal polyps; secretory phospholipase A2; transglutaminase 2; Wnt5a; AEC; Airway epithelial cell; ASMC; Airway smooth
Similar Responses of Intestinal T Cells From Untreated Children and Adults With Celiac Disease to Deamidated Gluten Epitopes
Keywords: ترانس گلوتامیناز 2; Autoimmunity; CD4+ T Cell; TG2; PreventCD Study; CT-gluten; chymotrypsin digest of gluten; IL; interleukin; PT-gliadin; pepsin-trypsin digest of gliadin; TCC; T-cell clone; TCL; T-cell line; TCR; T-cell receptor; TG2; transglutaminase 2;
Mineralization-inhibiting effects of transglutaminase-crosslinked polymeric osteopontin
Keywords: ترانس گلوتامیناز 2; OPN; osteopontin; SIBLING; Small, Integrin-Binding LIgand N-linked Glycoprotein; PHEX; Phosphate-regulating gene with Homologies to Endopeptidase on the X chromosome; TGs; transglutaminases; TG2; transglutaminase 2 (tissue transglutaminase); iTG2; inactiv
Immobilization of proteins onto microbeads using a DNA binding tag for enzymatic assays
Keywords: ترانس گلوتامیناز 2; scCro; OR consensus DNA; Transglutaminase 2; Manganese peroxidase; Flow cytometry; Cell-free protein synthesis
Real-time kinetic method to monitor isopeptidase activity of transglutaminase 2 on protein substrate
Keywords: ترانس گلوتامیناز 2; Transglutaminase 2; S100A4; Isopeptidase activity; Fluorescence anisotropyTG2, transglutaminase 2; BSA, bovine serum albumin; EDTA, ethylenediaminetetraacetic acid; DTT, dithiothreitol; SDS–PAGE, sodium dodecyl sulfate–polyacrylamide gel electrophoresis;
Inhibition of transglutaminase 2 reduces efferocytosis in human macrophages: Role of CD14 and SR-AI receptors
Keywords: ترانس گلوتامیناز 2; Transglutaminase 2; Cystamine; Macrophages; Efferocytosis; Interleukin-10; CD14 antigen; Scavenger receptor SR-AI;
An unprecedented dual antagonist and agonist of human Transglutaminase 2
Keywords: ترانس گلوتامیناز 2; Transglutaminase 2; Celiac disease; Oxoindole; Allostery;
The activation status of human macrophages presenting antigen determines the efficiency of Th17 responses
Keywords: ترانس گلوتامیناز 2; Antigen presentation; Human; Macrophage activation; T cell polarisation; Th17; APC; antigen presenting cell; DC; dendritic cell; KLH; keyhole limpet haemocyanin; PPD; purified protein derivative; SOCS; suppressor of cytokine signalling; TGM2; transglutami
Tissue transglutaminase promotes serotonin-induced AKT signaling and mitogenesis in pulmonary vascular smooth muscle cells
Keywords: ترانس گلوتامیناز 2; MDC; monodansylcadaverine; PASMC; pulmonary arterial smooth muscle cells; 5-HT; 5-hydroxytryptamine (serotonin); SERT; serotonin transporter; TG2; transglutaminase 2 aka tissue transglutaminase; Transglutaminase 2; AKT; S6K; S6; Serotonin; SERT;
Glutenase ALV003 Attenuates Gluten-Induced Mucosal Injury in Patients With Celiac Disease
Keywords: ترانس گلوتامیناز 2; Duodenal Biopsy; Drug Treatment; Morphometry; Clinical Trial; AE; adverse event; CDQ; Celiac Disease Questionnaire; DGP; deamidated gliadin peptide; ELISA; enzyme-linked immunosorbent assay; EMA; endomysial antibody; GSRS; gastrointestinal symptom rating
Methylglyoxal in cells elicits a negative feedback loop entailing transglutaminase 2 and glyoxalase 1
Keywords: ترانس گلوتامیناز 2; Transglutaminase 2; Glyoxalase 1; Methylglyoxal; Oxidative stress
A possible role of transglutaminase 2 in the nucleus of INS-1E and of cells of human pancreatic islets
Keywords: ترانس گلوتامیناز 2; FPIS; first phase insulin secretion; TG2; transglutaminase 2.; Transglutaminase 2; Insulin secretion; Calcium concentration; β-Cell; INS-1E; Human islet;
Comparative characterization of direct and indirect substrate probes for on-chip transamidating activity assay of transglutaminases
Keywords: ترانس گلوتامیناز 2; On-chip activity assay; Transglutaminase 2; Factor XIII; Substrate probes; Biotin-cadaverine;
Transglutaminase 2 facilitates or ameliorates HIF signaling and ischemic cell death depending on its conformation and localization
Keywords: ترانس گلوتامیناز 2; TG2; transglutaminase 2; HIF; hypoxia inducible factor; HRE; hypoxia response element; XRE; xenobiotic response element; OGD; oxygen glucose deprivation; NLS; nuclear localization signal; NES; nuclear export signal; CAT; catalytic; ChIP; chromatin immunop
Gliadin Does Not Induce Mucosal Inflammation or Basophil Activation in Patients With Nonceliac Gluten Sensitivity
Keywords: ترانس گلوتامیناز 2; Allergy; Duodenal Immune Response; Diagnostic; In Vitro Challenge; AGA; antigliadin antibodies; a-tTG; anti-tissue transglutaminase antibody; CD; celiac disease; EMA; anti-endomysium antibody; FD; free diet; GFD; gluten-free diet; HC; healthy control; IC
Implication for transglutaminase 2-mediated activation of β-catenin signaling in neointimal vascular smooth muscle cells in chronic cardiac allograft rejection
Keywords: ترانس گلوتامیناز 2; cardiac allograft vasculopathy; β-catenin signaling; vascular smooth muscle cells; transglutaminase 2; platelet derived growth factor;
Transglutaminase 2: A molecular Swiss army knife
Keywords: ترانس گلوتامیناز 2; Transglutaminase 2; Transcription regulation; Transamidase; Calcium; GTP; Cell death;
Acylideneoxoindoles: A new class of reversible inhibitors of human transglutaminase 2
Keywords: ترانس گلوتامیناز 2; Transglutaminase 2; Oxoindole; Celiac sprue; Structure–activity relationships; Allostery
Transglutaminase 2 regulates early chondrogenesis and glycosaminoglycan synthesis
Keywords: ترانس گلوتامیناز 2; Chondrocyte; Mesenchymal cells; Transglutaminase 2; Glycosaminoglycan; PKA; Cell differentiation
Tolerance to Ingested Deamidated Gliadin in Mice is Maintained by Splenic, Type 1 Regulatory T Cells
Keywords: ترانس گلوتامیناز 2; Food Allergy; Mucosal Tolerance Induction; Treg Cells; Immune Regulation; BM-DC; bone marrow-derived dendritic cells; DC; dendritic cell; DTH; delayed-type hypersensitivity; FACS; fluorescence-activated cell sorter; IFN; interferon; IL; interleukin; MLN
Diagnostic methods beyond conventional histology in coeliac disease diagnosis
Keywords: ترانس گلوتامیناز 2; Coeliac disease; Endomysial antibodies; Intraepithelial lymphocytes; IgA deposit; Transglutaminase 2
Transglutaminase 2 gene ablation protects against renal ischemic injury by blocking constant NF-κB activation
Keywords: ترانس گلوتامیناز 2; Transglutaminase 2; Transglutaminase 2 knockout mouse; Unilateral ureteral obstruction; Ischemia; Nuclear factor-κB; Renal injuryTGase 2, transglutaminase 2; NF-κB, nuclear factor-κB; I-κBα, inhibitory subunit of NF-κB; UUO, unilateral ureteral obstructio
Transglutaminase 2-targeted autoantibodies in celiac disease: Pathogenetic players in addition to diagnostic tools?
Keywords: ترانس گلوتامیناز 2; Celiac disease; Gliadin; Transglutaminase 2; Autoantibody
Effect of transglutaminase 2 (TG2) deficiency on atherosclerotic plaque stability in the apolipoprotein E deficient mouse
Keywords: ترانس گلوتامیناز 2; Transglutaminase 2; Apolipoprotein E; Plaque stability; Calcification; Mouse;
Transglutaminase 2 expression levels regulate sensitivity to cystamine plus TRAIL-mediated apoptosis
Keywords: ترانس گلوتامیناز 2; TRAIL; Cystamine; c-FLIP; Apoptosis; Transglutaminase 2
The role of transglutaminase 2 and osteopontin in matrix protein supplemented microencapsulation of marrow stromal cells
Keywords: ترانس گلوتامیناز 2; Cell therapy; Mesenchymal stem cells (MSCs); Microencapsulation; Extracellular matrix (ECM); Osteopontin; Transglutaminase 2
Transglutaminase 2 protects against ischemic stroke
Keywords: ترانس گلوتامیناز 2; Transglutaminase 2; Stroke; Ischemia; Hypoxia; Hypoxia inducible factor; Neuron; Noxa;
Glucosamine is an effective chemo-sensitizer via transglutaminase 2 inhibition
Keywords: ترانس گلوتامیناز 2; Transglutaminase 2; Drug resistance; Glucosamine; NF-κB; I-κBα; IKK
Over-expression of integrin β3 can partially overcome the defect of integrin β3 signaling in transglutaminase 2 null macrophages
Keywords: ترانس گلوتامیناز 2; Macrophages; Apoptotic cells; Transglutaminase 2; Integrin signaling