دانلود مقالات ISI درباره حمل و نقل + ترجمه فارسی

FhuA interactions in a detergent-free nanodisc environment

Keywords: حمل و نقل; BN; blue-native; CN; clear-native; DDM; dodecyl-β-d-maltoside; LDAO; N-lauryldimethyl amine-N-oxide; Fc; ferricrocin; ITC; isothermal titration calorimetry; MSP; membrane scaffold protein; Membrane; Transporters; β-Barrel proteins; Channels; Nanodiscs;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Le passage transplacentaire des médicaments

Keywords: حمل و نقل; placenta; médicaments; modèles in vitro; perfusion placentaire; transporteurs; placenta; drugs; in vitro models; placental perfusion; transporters; ABC; adenosine triphosphate-bindingcassette; AGA; α-1 glycoprotéine acide; AMM; autorisation de mise su

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Blood pressure effects of sodium–glucose co-transport 2 (SGLT2) inhibitors

Keywords: حمل و نقل; Diabetes; hypertension; glucose; transporters; SGLT2

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Transport proteins promoting Escherichia coli pathogenesis

Keywords: حمل و نقل; Escherichia coli; Pathogenesis; Transporters; Toxins; Iron acquisition; Intra vs. extracellular pathogens

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2014 سفارش ترجمه

Inhibition of ileal apical but not basolateral bile acid transport reduces atherosclerosis in apoE−/− mice

Keywords: حمل و نقل; Bile acids; Cholesterol; apoE knockout mouse; Atherosclerosis; Fibroblast growth factor 15; Ileum; Transporters;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Renal Uptake of Substrates for Organic Anion Transporters Oat1 and Oat3 and Organic Cation Transporters Oct1 and Oct2 is Altered in Rats with Adenine-Induced Chronic Renal Failure

Keywords: حمل و نقل; adenine-induced CRF; distribution; elimination; kidney uptak clearance; pharmacokinetics; transport; transporters;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Domoic acid toxicokinetics in Dungeness crabs: New insights into mechanisms that regulate bioaccumulation

Keywords: حمل و نقل; Transporters; Disposition; Extracellular; Hepatopancreas;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Essentials of cell physiology

Keywords: حمل و نقل; Cell membrane; channels; oedema; organelles; signalling; transporters; volume regulation

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

The cell membrane and receptors

Keywords: حمل و نقل; Endocytosis; exocytosis; ion channels; phospholipids; transporters

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Relationship Between the Urinary Excretion Mechanisms of Drugs and Their Physicochemical Properties

Keywords: حمل و نقل; renal clearance; renal transport; renal reabsorption; transporters; physicochemical

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Investigation of the effect of active efflux at the blood–brain barrier on the distribution of nonsteroidal aromatase inhibitors in the central nervous system

Keywords: حمل و نقل; blood–brain barrier; CNS; disposition; efflux pumps; P-glycoprotein; endothelial; transporters

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Kinetic Analysis of Human and Canine P-Glycoprotein-Mediated Drug Transport in MDR1-MDCK Cell Model: Approaches to Reduce False-Negative Substrate Classification

Keywords: حمل و نقل; ABC transporters; transporters; P-glycoprotein; MDCK cells; mathematical model; membrane transporter; in vitro model; drug transport; drug interactions

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Investigation of the role of transporters on the hepatic elimination of an LAT1 selective inhibitor JPH203

Keywords: حمل و نقل; ADME; biliary excretion; bioavailability; cancer chemotherapy; hepatocytes; transporters

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Absolute measurement of species differences in sodium taurocholate cotransporting polypeptide (NTCP/Ntcp) and its modulation in cultured hepatocytes

Keywords: حمل و نقل; target proteomics; hepatic transport; hepatocytes; LC–MS/MS; NTCP; transporters

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Selectivity in the impact of P-glycoprotein upon pulmonary absorption of airway-dosed substrates: A study in ex vivo lung models using chemical inhibition and genetic knockout

Keywords: حمل و نقل; isolated perfused rat lung (IPRL); isolated perfused mouse lung (IPML); transporters; active transport; efflux pumps; passive transport; permeability; pulmonary delivery

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Amino acids as promoieties in prodrug design and development

Keywords: حمل و نقل; Solubility; Permeability; Hydrolysis; Stability; Drug delivery; Targeting; Transporters; Formulation; Challenges

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2013 سفارش ترجمه

An updated review on drug-induced cholestasis: Mechanisms and investigation of physicochemical properties and pharmacokinetic parameters

Keywords: حمل و نقل; drug-induced cholestasis; bile acid; transporters; physicochemical properties; pharmacokinetic parameters; in silico modeling

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2013 سفارش ترجمه

Carrier-mediated γ-aminobutyric acid transport across the basolateral membrane of human intestinal Caco-2 cell monolayers

Keywords: حمل و نقل; GABA; δ-Aminolevulinic acid; Basolateral transport; Caco-2 cells; Transporters

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Absorption and Bioavailability of Glucosamine in the Rat

Keywords: حمل و نقل; absorption; active transport; bioavailability; intestinal metabolism; transporters;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Long-Lasting Inhibition of the Intestinal Absorption of Fexofenadine by Cyclosporin a in Rats

Keywords: حمل و نقل; intestinal absorption; drug interactions; OATP; transporters; membrane transport; bioavailability; cyclosporin A; fexofenadine;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Differential Selectivity of Efflux Transporter Inhibitors in Caco-2 and MDCK-MDR1 Monolayers: A Strategy to Assess the Interaction of a New Chemical Entity with P-gp, BCRP, and MRP2

Keywords: حمل و نقل; ABC transporters; MDCK cells; active transport; Caco-2 cells; transporters; P-glycoprotein; membrane transporter; in vitro models; intestinal absorption; multidrug resistance transporters;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Pharmacokinetic and Pharmacodynamic Modeling for the Effect of Sodium-Glucose Cotransporter Inhibitors on Blood Glucose Level and Renal Glucose Excretion in db/db Mice

Keywords: حمل و نقل; pharmacokinetic/pharmacodynamic models; mathematical model; renal transport; simulations; transporters; SGLT inhibitor; blood glucose; renal glucose excretion; db/db mice;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Insights into physiological traits of Bifidobacterium animalis subsp. lactis BB-12 through membrane proteome analysis

Keywords: حمل و نقل; Bifidobacterium; LC–MS; Membrane proteomics; Probiotics; Transporters

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Assessment of Biliary Clearance in Early Drug Discovery using Sandwich-cultured Hepatocyte Model

Keywords: حمل و نقل; biliary excretion; hepatobiliary disposition; drug interactions; in vitro-in vivo correlations (IVIVC); hepatic clearance; permeability; transporters; hepatocytes;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

GABA, glutamate, dopamine and serotonin transporters expression on forgetting

Keywords: حمل و نقل; Forgetting; Autoshaping; Transporters; Serorotonin; Glutamate; GABA; Dopamine; Drugs

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Prediction of the in vivo OATP1B1-mediated drug–drug interaction potential of an investigational drug against a range of statins

Keywords: حمل و نقل; Transporters; Drug–drug interactions (DDI); In vitro; OATP1B1; Statins; US Food and Drug Administration (US FDA)

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

GABA, glutamate, dopamine and serotonin transporters expression on memory formation and amnesia

Keywords: حمل و نقل; Memory; Amnesia; Neurotransmission systems; Transporters; Autoshaping; Rats; Drugs;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2012 سفارش ترجمه

The Effects of Media on Pharmaceutically Relevant Transporters in the Human HT-29 Adenocarcinoma Cell Line: Does Culture Media Need to be Controlled?

Keywords: حمل و نقل; Caco-2 cells; peptide drug delivery; drug transport; in vitro models; transporters; peptide transporters; polymerase chain reaction; solute transporters; ABC transporters; permeability;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2012 سفارش ترجمه

Transporter-Targeted Lipid Prodrugs of Cyclic Cidofovir: A Potential Approach for the Treatment of Cytomegalovirus Retinitis

Keywords: حمل و نقل; transporters; bioavailability; drug transport; HIV/AIDS; lipids; MDCK cells; membrane transport; ophthalmic drug delivery; prodrugs; targeted drug delivery

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2012 سفارش ترجمه

Development of a Physiologically Based Pharmacokinetic Model for the Rat Central Nervous System and Determination of an In Vitro-In Vivo Scaling Methodology for the Blood-Brain Barrier Permeability of Two Transporter Substrates, Morphine and Oxycodone

Keywords: حمل و نقل; BBB; blood-brain barrier; Caco-2 cells; CNS; IVIVE; PBPK; pharmacokinetics; physiological model scaling; transporters;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2012 سفارش ترجمه

The effects of intralaboratory modifications to media composition and cell source on the expression of pharmaceutically relevant transporters and metabolizing genes in the Caco‐2 cell line

Keywords: حمل و نقل; Caco‐2 cells; cell culture; variability; media composition; active transport; paracellular transport; transporters; gene expression; permeability; intestinal metabolism;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2012 سفارش ترجمه

Molecular basis of essential amino acid transport from studies of insect nutrient amino acid transporters of the SLC6 family (NAT-SLC6)

Keywords: حمل و نقل; Insect nutrition; Essential amino acids; Epithelial absorption; Transporters; Midgut; Alimentary canal

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2012 سفارش ترجمه

Pt-rotaxanes as cytotoxic agents

Keywords: حمل و نقل; Transporters; Rotaxanes; Pt-drugs

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

Essentials of cell physiology

Keywords: حمل و نقل; Cell membrane; channels; oedema; organelles; signalling; transporters; volume regulation

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

Effect of Early Glutamate Exposure on EAAT-3 and GAT-1 Protein Expression in Cells of the Dentate Gyrus and CA1 Region of the Adult Rat Hippocampus

Keywords: حمل و نقل; EAAT-3; GAT-1; Hippocampus; Immunofluorescence; Monosodium glutamate; Transporters

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Reliability and Robustness of Simultaneous Absolute Quantification of Drug Transporters, Cytochrome P450 Enzymes, and Udp-Glucuronosyltransferases in Human Liver Tissue by Multiplexed MRM/Selected Reaction Monitoring Mode Tandem Mass Spectrometry with Nan

Keywords: حمل و نقل; multiplexed MRM quantification of proteins; transporters; membrane transporter; cytochrome P450; UDP-glucuronosyltransferases; nano-LC; LC–MS/MS; mass spectrometry; proteomics

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Permeation and Systemic Absorption of R- and S-Baclofen Across the Nasal Mucosa

Keywords: حمل و نقل; nasal absorption; nasal drug delivery; permeability; transporters; bioavailability; pharmacokinetics;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

The Regulation of Renal Phosphate Transport

Keywords: حمل و نقل; PTH; Phosphate; Transporters; Proximal tubule; Regulation;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

The Oligopeptide Transporters: A Small Gene Family with a Diverse Group of Substrates and Functions?

Keywords: حمل و نقل; Molecular transport; nutrient and metal transport; transporters; Oligopeptide Transporters

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Ultrastructural analysis, zinc transporters, glucose transporters and hormones expression in new world primate (Callithrix jacchus) and human pancreatic islets

Keywords: حمل و نقل; Marmoset (Callithrix jacchus); Transporters; Ultrastructure; Pancreatic islets; Zinc

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

In vitro risk assessment of AZD9056 perpetrating a transporter-mediated drug–drug interaction with methotrexate

Keywords: حمل و نقل; Transporters; Drug development; Breast cancer resistance protein; Drug–drug interactions; Rheumatoid arthritis; Methotrexate

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

Evaluation of Transport Mechanism of Prodrugs and Parent Drugs Formed by Intracellular Metabolism in Caco-2 Cells with Modified Carboxylesterase Activity: Temocapril as a Model Case

Keywords: حمل و نقل; Caco-2 cells; prodrugs; metabolism; intestinal absorption; membrane transport; inhibition; transporters; peptide transporters; multidrug resistance-associated proteins; P-glycoprotein

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Potassium and sodium uptake systems in fungi. The transporter diversity of Magnaporthe oryzae

Keywords: حمل و نقل; Potassium; Sodium; Transporters; Fungi;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

The role of lithocholic acid in the regulation of bile acid detoxication, synthesis, and transport proteins in rat and human intestine and liver slices

Keywords: حمل و نقل; Lithocholic acid; VDR; FXR; PXR; GR; Intestinal slices; Liver slices; Cytochrome P450; Transporters; Bile acid; Induction

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Establishment of In Vitro P-Glycoprotein Inhibition Assay and Its Exclusion Criteria to Assess the Risk Of Drug–Drug Interaction at the Drug Discovery Stage

Keywords: حمل و نقل; P-glycoprotein; in vitro models; P-gp inhibition; transporters; digoxin; drug interactions; difference of IC50 values; mathematical model; risk assessment for DDI; pharmacokinetics

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Inner Blood–Retinal Barrier Mediates L-Isomer-Predominant Transport of Serine

Keywords: حمل و نقل; l-serine; d-serine; system ASC; blood–retinal barrier; blood–brain barrier; transporters; active transport; distribution; pharmacokinetics; endothelial cell

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

Quantitative Membrane Protein Expression at the Blood-Brain Barrier of Adult and Younger Cynomolgus Monkeys

Keywords: حمل و نقل; blood-brain barrier; transporters; ABC transporters; P-glycoprotein; CNS; membrane transporter; proteomics; mass spectrometry;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

Development of a new permeability assay using low‐efflux MDCKII cells

Keywords: حمل و نقل; absorption; P‐glycoprotein; ADME; drug transport; in vitro models; bioavailability; LC-MS; Biopharmaceutics Classification System (BCS); cell culture; MDCK cells; transporters;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

Synthesis and In Vitro Evaluation of Gabapentin Prodrugs that Target the Human Apical Sodium-Dependent Bile Acid Transporter (hASBT)

Keywords: حمل و نقل; transporters; prodrugs; gabapentin; apical sodium-dependent bile acid transporter; bile acid; active transport; bioavailability; permeability; stability;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

Transporters Contributing to Iron Trafficking in Plants

Keywords: حمل و نقل; Nutrient and metal transport; transporters; gene regulation; iron; nicotianamine; phytosiderophores

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2011 سفارش ترجمه