DNAJB1 destabilizes PDCD5 to suppress p53-mediated apoptosis
Keywords: یوبی کوئیتینه شدن ; DNAJB1; PDCD5; p53; Ubiquitination; Apoptosis;
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Cbl-b and c-Cbl negatively regulate osteoblast differentiation by enhancing ubiquitination and degradation of Osterix
Keywords: یوبی کوئیتینه شدن ; Cbl; Osterix; Ubiquitination; Osteoblast differentiation;
PKCβII inhibits the ubiquitination of β-arrestin2 in an autophosphorylation-dependent manner
Keywords: یوبی کوئیتینه شدن ; Conventional PKC; β-Arrestin; Ubiquitination; Autophosphorylation; GPCR kinase 2; G protein-coupled receptor;
E3 ligase CHIP and Hsc70 regulate Kv1.5 protein expression and function in mammalian cells
Keywords: یوبی کوئیتینه شدن ; Kv1.5 protein; CHIP E3 ligase; Hsc70; Ubiquitination; Proteasome;
Mitophagy and mitochondrial dynamics in Saccharomyces cerevisiae
Keywords: یوبی کوئیتینه شدن ; AIM; Atg8 family interacting motif; ALP; alkaline phosphatase; Ape1; aminopeptidase I; ATG; autophagy-related; CCCP; carbonyl cyanide m-chlorophenylhydrazone; CJ; crista junction; CM; cristae membrane; CMA; chaperone-mediated autophagy; Cvt; cytoplasm to
Crosstalk between translesion synthesis, Fanconi anemia network, and homologous recombination repair pathways in interstrand DNA crosslink repair and development of chemoresistance
Keywords: یوبی کوئیتینه شدن ; Interstrand DNA crosslinks; Ubiquitination; Rad6; PCNA
CD166 positively regulates MCAM via inhibition to ubiquitin E3 ligases Smurf1 and βTrCP through PI3K/AKT and c-Raf/MEK/ERK signaling in Bel-7402 hepatocellular carcinoma cells
Keywords: یوبی کوئیتینه شدن ; Apoptosis; Ubiquitination; Signaling transduction; Tumorigenesis; Membrane protein;
BCAS2 interacts with HSF4 and negatively regulates its protein stability via ubiquitination
Keywords: یوبی کوئیتینه شدن ; HSF4; Lens; BCAS2; αB-crystallin; Ubiquitination;
Similarities and differences between Arabidopsis PCNA1 and PCNA2 in complementing the yeast DNA damage tolerance defect
Keywords: یوبی کوئیتینه شدن ; Arabidopsis; PCNA; Ubiquitination; Sumoylation; DNA damage tolerance; Protein–protein interaction
Selenoprotein W controls epidermal growth factor receptor surface expression, activation and degradation via receptor ubiquitination
Keywords: یوبی کوئیتینه شدن ; ANOVA, analysis of variance; CHX, cycloheximide; BS3, bis(sulfosuccinimidyl)suberate; SE, standard error of the mean; Sec, selenocysteineSelenium; Selenoprotein W; Epidermal growth factor receptor; Ubiquitination; Cancer
Low level DNA damage occurs as PAMPs, chitin and flg22, activates PR genes, and increases pisatin and disease resistance in pea endocarp tissue
Keywords: یوبی کوئیتینه شدن ; PR gene transcription; Ubiquitination; Histones H2A/H2B; Chitosan; Chitin oligomers; Calyculin A
Heat shock protein gp96 decreases p53 stability by regulating Mdm2 E3 ligase activity in liver cancer
Keywords: یوبی کوئیتینه شدن ; gp96; Apoptosis; Ubiquitination; Chaperone
Trim21 regulates Nmi-IFI35 complex-mediated inhibition of innate antiviral response
Keywords: یوبی کوئیتینه شدن ; Trim21; IFI35; Nmi; ISG; Innate antiviral signaling; Ubiquitination;
Ubiquitin conjugating enzyme E2-N and sequestosome-1 (p62) are components of the ubiquitination process mediated by the malin-laforin E3-ubiquitin ligase complex
Keywords: یوبی کوئیتینه شدن ; LD; Lafora disease; RING; really interesting new gene; SDS-PAGE; sodium dodecylsulfate electrophoresis; SQSTM1; sequestosome-1; UBE2B2; ubiquitin conjugating enzyme E2-D2; UBE2N; ubiquitin conjugating enzyme E2-N; UBE2N; E2-conjugase; p62 (SQSTM1); Ubiq
Improved plasma membrane expression of the trafficking defective P344R mutant of muscle, skeletal, receptor tyrosine kinase (MuSK) causing congenital myasthenic syndrome
Keywords: یوبی کوئیتینه شدن ; Muscle, skeletal, receptor tyrosine kinase (MuSK); Congenital Myasthenic Syndromes (CMSs); Endoplasmic Reticulum Associated Degradation (ERAD); Trafficking; Neuromuscular junction; Ubiquitination; Proteasome; Protein misfolding;
The dichotomy of the Insulin-like growth factor 1 receptor: RTK and GPCR: friend or foe for cancer treatment?
Keywords: یوبی کوئیتینه شدن ; IGF-1R; RTK; GPCR; beta-Arrestin; GRK; Biased signalling; Cancer; Ubiquitination;
Activation of AHR mediates the ubiquitination and proteasome degradation of c-Fos through the induction of Ubcm4 gene expression
Keywords: یوبی کوئیتینه شدن ; Aryl hydrocarbon receptor; Ubiquitination; UbcM4; c-Fos; TCDD;
Sch9 regulates intracellular protein ubiquitination by controlling stress responses
Keywords: یوبی کوئیتینه شدن ; SCH9; Yeast; Ubiquitination; Oxidation; Hydrogen peroxide
Roles of ubiquitination-mediated protein degradation in plant responses to abiotic stresses
Keywords: یوبی کوئیتینه شدن ; Ubiquitination; E3 ligase; Plants; Abiotic stress; Signaling
RIP1 modulates death receptor mediated apoptosis and autophagy in macrophages
Keywords: یوبی کوئیتینه شدن ; Tumor necrosis factor-related apoptosis-inducing ligand; Apoptosis; Autophagy; RIP1; Ubiquitination; Deathc-FLIP, cellular FLICE inhibitory protein; DISC, death-inducing signaling complex; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; LC3, microtubule-
Overexpression of alpha-synuclein at non-toxic levels increases dopaminergic cell death induced by copper exposure via modulation of protein degradation pathways
Keywords: یوبی کوئیتینه شدن ; α-Synuclein; A53T; Autophagy; Proteasome; Ubiquitination; Oxidative stress; AMPK; Copper and Parkinson's disease;
Role of post-translational modifications on structure, function and pharmacology of class C G protein-coupled receptors
Keywords: یوبی کوئیتینه شدن ; GPRC6A; CaSR; mGluR; Post-translational modifications; Glycosylation; Phosphorylation; Ubiquitination; Palmitoylation;
Functional role of lysine 12 in Leishmania major AQP1
Keywords: یوبی کوئیتینه شدن ; Sb(III); antimonite; AQP1; Leishmania major aquaglyceroporin; MPK2; Leishmania major mitogen-activated protein kinase 2; Antimonite; Aquaglyceroporin; Leishmania; Post-translational regulation; Ubiquitination; Volume regulation;
Participation of proteasome-ubiquitin protein degradation in autophagy and the activation of AMP-activated protein kinase
Keywords: یوبی کوئیتینه شدن ; AMPK; AMP-activated protein kinase AICAR; ROS; reactive oxygen species; ÎÏm; mitochondrial membrane potential; AMP kinase; Bioenergetics; Proteasome; Ubiquitination; Autophagy; PARK2;
Ubiquitin C-terminal hydrolase L1 interacts with choline transporter in cholinergic cells
Keywords: یوبی کوئیتینه شدن ; UCHL1; CHT; Acetylcholine; Ubiquitination; SN56 cells;
Prostaglandin receptor EP1-mediated differential degradation of cyclooxygenases involves a specific lysine residue
Keywords: یوبی کوئیتینه شدن ; Cyclooxygenase; COX-2; COX-1; EP1; Ubiquitination; Degradation;
Ubiquitin proteasome system-mediated degradation of synaptic proteins: An update from the postsynaptic side
Keywords: یوبی کوئیتینه شدن ; Ubiquitination; Synapse; E3 ligase; Plasticity; Proteasome; Neuronal activity;
Ubiquitin ligase Cbl-b acts as a negative regulator in discoidin domain receptor 2 signaling via modulation of its stability
Keywords: یوبی کوئیتینه شدن ; DDR2; Collagen receptor; Ubiquitination; Degradation; Cbl-b;
Cbl regulates the activity of SIRT2
Keywords: یوبی کوئیتینه شدن ; SIRT2; Cbl; Protein stability; Ubiquitination
Cytohesin-associated scaffolding protein (CASP) is a substrate for granzyme B and ubiquitination
Keywords: یوبی کوئیتینه شدن ; NK cell; CASP; Granzyme B; Ubiquitination;
Cancer-testis antigen HCA587/MAGE-C2 interacts with BS69 and promotes its degradation in the ubiquitin-proteasome pathway
Keywords: یوبی کوئیتینه شدن ; Cancer-testis antigen; HCA587; BS69; Ubiquitination;
A site-directed mutagenesis study of the MdmX RING domain
Keywords: یوبی کوئیتینه شدن ; Mdm; Murine Double Minute; RING; Really Interesting New Gene; Mdm2; MdmX; E3 ligase; Ubiquitination;
eEF1Bγ is a positive regulator of NF-кB signaling pathway
Keywords: یوبی کوئیتینه شدن ; NF-кB signaling pathway; Mitochondrial antiviral-signaling protein (MAVS); Eukaryotic elongation factor 1B gamma (eEF1Bγ); Ubiquitination;
Classification and interaction modes of 40 rice E2 ubiquitin-conjugating enzymes with 17 rice ARM-U-box E3 ubiquitin ligases
Keywords: یوبی کوئیتینه شدن ; HECT; homology to E6-AP carboxyl-terminus; MBP; maltose binding protein; PCR; polymerase chain reaction; RING; really interesting new gene; E2 ubiquitin-conjugating enzyme; ARM-U-box E3 ubiquitin-ligase; E2-E3 interaction; Rice (Oryza sativa L.); Ubiqui
Wwp2 targets SRG3, a scaffold protein of the SWI/SNF-like BAF complex, for ubiquitination and degradation
Keywords: یوبی کوئیتینه شدن ; Ubiquitination; Wwp2; SRG3; SWI/SNF-like BAF complex; Protein stability;
Underwater trauma causes a long-term specific increase in the expression of cyclooxygenase-2 in the ventral CA1 of the hippocampus
Keywords: یوبی کوئیتینه شدن ; Cyclooxygenase-2; Mdm2; Emotional trauma; Hippocampus; Ubiquitination; Elevated plus maze; Underwater trauma; Post trauma;
Ubiquitin in the peroxisomal protein import pathway
Keywords: یوبی کوئیتینه شدن ; Ubiquitination; Peroxisome; PEX5; Thioester; Protein trafficking; AAA; ATPases associated with diverse cellular activities; DTM; docking/translocation module; DUBs; deubiquitinating enzymes; E1; ubiquitin-activating enzyme; E2; ubiquitin-conjugating enzym
Chronic morphine treatment induces over-expression of HSP70 in mice striatum related with abnormal ubiquitin-proteasome degradation
Keywords: یوبی کوئیتینه شدن ; Heat shock protein 70; Morphine dependence; Opioid withdrawal; Striatum; Ubiquitination;
HDAC6 mediates the acetylation of TRIM50
Keywords: یوبی کوئیتینه شدن ; TRIM50; HDAC6; Acetylation; Ubiquitination; NES;
The splicing factor U2AF65 stabilizes TRF1 protein by inhibiting its ubiquitin-dependent proteolysis
Keywords: یوبی کوئیتینه شدن ; TRF1; U2AF65; Fbx4; Telomere; Ubiquitination;
Rock2 promotes the invasion and metastasis of hepatocellular carcinoma by modifying MMP2 ubiquitination and degradation
Keywords: یوبی کوئیتینه شدن ; Hepatocellular carcinoma; Invasion; Metastasis; Rock2; MMP2; Ubiquitination
SIPL1-facilitated PTEN ubiquitination contributes to its association with PTEN
Keywords: یوبی کوئیتینه شدن ; SIPL1/sharpin; PTEN; Ubiquitination; Protein-protein interaction;
TRIB2 inhibits Wnt/β-Catenin/TCF4 signaling through its associated ubiquitin E3 ligases, β-TrCP, COP1 and Smurf1, in liver cancer cells
Keywords: یوبی کوئیتینه شدن ; TRIB2; Tribbles homolog 2; CHX; cycloheximide; Smurf1; Smad ubiquitination regulatory factor 1; β-TrCP; beta-transducin repeat-containing E3 ubiquitin protein ligase; Ub; ubiquitin; IF; immunofluorescence; WB; Western blotting; Protein stability; Wnt/β-
Alteration of miRNA activity via context-specific modifications of Argonaute proteins
Keywords: یوبی کوئیتینه شدن ; Argonaute; miRNA; hydroxylation; phosphorylation; ubiquitination; PARylation
A Feedback Loop between RUNX2 and the E3 Ligase SMURF1 in Regulation of Differentiation of Human Dental Pulp Stem Cells
Keywords: یوبی کوئیتینه شدن ; Adult stem cell research; cell differentiation; dental pulps; feedback; ligases; mesenchymal stem cells; runt-related transcription factor 2; smad ubiquitylation regulatory factor-1; ubiquitination
Sesamin increases heme oxygenase-1 protein in RAW 264.7 macrophages through inhibiting its ubiquitination process
Keywords: یوبی کوئیتینه شدن ; Sesamin; Heme oxygenase-1; Ubiquitination; Macrophage;
Cbl negatively regulates erythropoietin-induced growth and survival signaling through the proteasomal degradation of Src kinase
Keywords: یوبی کوئیتینه شدن ; Cbl; Erythropoietin; Proteasome; Src; Ubiquitination;
Airborne acrolein induces keratin-8 (Ser-73) hyperphosphorylation and intermediate filament ubiquitination in bronchiolar lung cell monolayers
Keywords: یوبی کوئیتینه شدن ; c:t; control:treated ratio; CV; coefficient of variation; DPBS; Dulbeccos phosphate buffered saline; FITC; fluorescein isothiocyanate; pK8-Ser73; phospho-keratin-8 (Ser73); TEER; transepithelial electrical resistance; Acrolein; Air-liquid interface; Ker
Parkin ubiquitinates mTOR to regulate mTORC1 activity under mitochondrial stress
Keywords: یوبی کوئیتینه شدن ; mTOR; mTORC1; Parkin; Ubiquitination; Mitochondrial stress;
Enhanced ubiquitin-dependent degradation by Nedd4 protects against α-synuclein accumulation and toxicity in animal models of Parkinson's disease
Keywords: یوبی کوئیتینه شدن ; Lysosome; Ubiquitination; Protein-degradation; Endosomal-trafficking;