Keywords: V-ATPase; Bafilomycin; Vas deferens fluid; Testosterone;
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Keywords: kidney calculi; nephrolithiasis; precision medicine; genetics; hypercalciuria; AKI; acute kidney injury; CaSR; calcium-sensing receptor; CKD; chronic kidney disease; dRTA; distal renal tubular acidosis; ESKD; end-stage kidney disease; HHRH; hereditary hyp
Keywords: DAMPs; danger associated molecular patterns; ER; endoplasmic reticulum; HMGB1; high mobility group box 1; IL-1Ra; IL-1 receptor antagonist; LPS; lipopolysaccharide; MS; mass spectrometry; PAMPs; pathogen associated molecular patterns; SDC; sodium deoxycho
Keywords: Bmax; maximum binding capacity; CNV; choroidal neovascularization; DCT; dopachrome tautomerase; DHI; 5,6-dihydroxyindole; DHICA; 5,6-dihydroxyindole-2-carboxylic acid; DOPA; dihydroxyphenylalanine; HPLC; high performance liquid chromatography; IQ; 5,6-ind
Keywords: AZ; active zone; BoNT; botulinum neurotoxin; CAZ; cytomatrix at the active zone; GFAP; glial fibrillary acidic protein; Munc; mammalian uncoordinated; Nrxn1; Neurexin 1-alpha; RABV; rabies virus; RIM; regulating synaptic membrane exocytosis protein; RIM-B
Keywords: AD; Alzheimer Disease; DS; Down Syndrome; Aβ; amyloid-β; HSA21; Chromosome 21; APP; Amyloid precursor protein; BACE1/2; β-site APP cleaving enzyme 1/2; βCTF; β carboxyl-terminal fragment; PSEN1; presenilin 1; APPL1; adaptor protein containing pleckst
Keywords: Growth factors; Angiogenesis; Innate lymphocytic cells; V-ATPase;
Keywords: UV; ultraviolet; PMF; polymethoxyflavone; Tyrp; tyrosinase-related protein; NHE; Na+/H+ exchanger; MSH; melanocyte-stimulating hormone; v-ATPase; vacuolar-type H+-adenosine triphosphatase; NCKX; Na+/Ca2+/K+ exchanger; FBS; fetal bovine serum; DMEM; Dulbec
Keywords: Breast cancer; Necrosis; Apoptosis; Cytotoxicity; Cancer therapeutics; HMA; 5-(N,N-hexamethylene) amiloride; DCFH-DA; carboxy-2â²,7â²-dichloro-dihydro-fluorescein diacetate; ROS; reactive oxygen species; PI3K; phosphatidylinositol-3 kinase; PKB; protein
Keywords: Osteoclast; Mathematical model; Acidification; V-ATPase; ClC-7; HV1;
Keywords: Cathelicidin; Helminth; Macrophage; Lysosome; Autoimmune disease; Toll like receptor; HDMs; helminth defence molecules; HDPs; cathelicidin-like host defence peptides; TLR; toll like receptor; v-ATPase; vacuolar H+-ATPase; DCs; dendritic cells; Th2; T help
Keywords: AQP5; aquaporin-5; BM; basement membrane; BPE; bovine pituitary extract; BSA; bovine serum albumin; CEA; carcinoembryonic antigen; CFTR; cystic fibrosis transmembrane conductance regulator; CJ; cell junctions; D; duct; DAPI; 4â², 6-diamidino-2-phenylindo
Keywords: Neurotrophins; Signalling endosome; Endosome acidification; Trk receptors; Membrane motility; Receptor internalization; AP-2; adaptor protein complex 2; BDNF; brain-derived neurotrophic factor; CREB; cAMP response element-binding protein; EEA1; early endo
Keywords: Japanese eel; Gill; Mitochondrion-rich cell; V-ATPase; NHE3; NKCC1a; Osmoregulation;
Keywords: ÎΨ; mitochondrial membrane potential; cmDCF; chloromethyldichlorofluorescein; cmH2DCF-DA; chloromethyldihydrodichlorofluorescein diacetate; IR; ischemia-reperfusion; KRH; Krebs-Ringer-Hepes; LTR; LysoTracker Red; MCU; mitochondrial Ca2+ uniporter;
Keywords: AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; ANOVA; Analysis of variance; Aβ; amyloid β; bHLH; basic Helix-Loop-Helix; C4; complement C4; CLEAR; coordinated lysosomal expression and regulation; Cyba; cytochrome b-245 light chain; DW; d
Keywords: AMD; Autophagy; βA3/A1-crystallin; Lysosome; mTORC1; Oxidative stress; RPE; V-ATPase
Genome-wide identification and transcript analysis of vacuolar-ATPase genes in citrus reveal their possible involvement in citrate accumulation
Keywords: Citric acid; Citrus; Fruit acidity; Fruit development; Vacuole-acidification; V-ATPase;
Vacuolar ATPase in phago(lyso)some biology
Keywords: DAMP; 3 (2,4-dinitroanilino)-30-amino-N-methyldipropylamine; mTORC1; mechanistic target of rapamycin complex 1; SNARE; soluble N-ethylmaleimide sensitive factor attachment protein receptors; V-ATPase; vacuolar ATPase; Intracellular pathogen; pH quantifica
Roles of VPH2 and VMA6 in localization of V-ATPase subunits, cell wall functions and filamentous development in Candida albicans
Keywords: Candida albicans; Vph2; Vma6; Cell wall; Hyphal development; Virulence; V-ATPase; the vacuolar-type H+-ATPase; CWI; cell wall integrity; ER; endoplasmic reticulum; UPR; unfolded protein response;
Analysis of two transcript isoforms of vacuolar ATPase subunit H in mouse and zebrafish
Keywords: V-ATPase; vacuolar ATPase; ATP6V1H; subunit H of vacuolar ATPase; SFD; sub fifty-eight-kDa dimer, or doublet; V-ATPase; Osteoclasts; ATP6V1H; Isoform; Alternative splicing; Zebrafish;
The Hog1p kinase regulates Aft1p transcription factor to control iron accumulation
Keywords: BPS; bathophenanthrolinedisulfonate; GST; glutathione S-transferase; PDS; post-diauxic-shift; TORC1; target of rapamycin complex 1; V-ATPase; vacuolar H+-ATPase; YPD; yeast extract peptone dextrose; Iron; Sphingomyelinase; Isc1p; Aft1p; Hog1p; Cell signal
Hepatocyte-specific deletion of LASS2 protects against diet-induced hepatic steatosis and insulin resistance
Keywords: DCF-DA; dichlorofluorescein diacetate; ERK1/2; extracellular signal-regulated kinase 1 and 2; GTTs; glucose tolerance tests; HFD; high-fat diet; ITTs; insulin tolerance tests; JNK/SAPK; c-Jun N-terminal kinase/stress activated protein kinase; KEGG; Kyoto
FLCN: The causative gene for Birt-Hogg-Dubé syndrome
Keywords: AEC; alveolar epithelial type II cell; AKT; protein kinase B; AMPK/Ampk; 5â²-AMP activated protein kinase; AMPKα (also AAK-2); AMPKα subunit; ATP; adenosine triphosphate; Bcl-2; B-cell lymphoma 2; BHD; Birt-Hogg-Dubé; BAT; brown adipose tissue; C. ele
JTC801 Induces pH-dependent Death Specifically in Cancer Cells and Slows Growth of Tumors in Mice
Keywords: Tumor Microenvironment; Drug Development; Targeted Therapy; Pancreas; AE; anion exchanger; CA; carbonic anhydrase; GPCR; G protein-coupled receptor; GPX; glutathione peroxidase; GSH; glutathione; HCQ; hydroxychloroquine; HMGB1; high mobility group box 1;
Autophagy as a pharmacological target in hematopoiesis and hematological disorders
Keywords: 3-MA; 3-methyladenine; ALL; acute lymphoblastic leukemia; AMKL; acute megakaryoblastic leukemia; AML; acute myeloid leukemia; AMPK; 5â²-adenosine monophosphate-activated protein kinase; APL; acute promyelocytic leukemia; Atg; autophagy-related proteins;
Energy and information flows in biological systems: Bioenergy transduction of V1-ATPase rotary motor and dynamics of thermodynamic entropy in information flows
Keywords: V-ATPase; Molecular rotary motor; Bioenergy transduction; Ergodicity; Entropy increase; Open quantum systems;
Pah1p negatively regulates the expression of V-ATPase genes as well as vacuolar acidification
Keywords: PAH1; Vacuole; V-ATPase; Vacuolar fusion; Gene expression; Vacuolar acidification;
(Pro)renin receptor as a therapeutic target for the treatment of cardiovascular diseases?
Keywords: Renin-angiotensin system; (Pro)renin receptor; V-ATPase; Cardiovascular diseases; Lipoprotein metabolism;
Haloacetophenones as newly potent nematicides against Meloidogyne incognita
Keywords: V-ATPase; vacuolar H+ adenosine triphosphate; DMSO; dimethyl sulfoxide; GC-MS; gas chromatography-mass spetrometry; SD; standard deviation; TMS; tetramethylsilane; Nematicidal compounds; V-ATPase; Metabolomics; 1-Dodecanol; Talose;
The vacuolar H+ ATPase V0 subunit d2 is associated with chondrocyte hypertrophy and supports chondrocyte differentiation
Keywords: Chondrocyte; Hypertrophy; Endochondral ossification; ATP6V0D2; Vacuolar H+-ATPase; ABH; alcian blue/haematoxylin/eosin/acid fuchsin stain; ATP6V0D2; vacuolar H+ ATPase V0 subunit d2; DAPI; 4â²,6-diamidino-2-phenylindole; DMEM; Dulbecco's modified Eagle's
Inhibition of stress induced premature senescence in presenilin-1 mutated cells with water soluble Coenzyme Q10
Keywords: Aβ; amyloid-beta peptide; AD; Alzheimer's disease; APP; amyloid precursor protein; CoQ10; Coenzyme Q10; DCF; 2â²,7â²-dichlorofluorescein; DIC; differential interference contrast; H2DCFDA; 2â²-7â²-dichlorofluorescin diacetate; HBSS; Hank's Balanced Sa
Dehydropachymic acid decreases bafilomycin A1 induced β-Amyloid accumulation in PC12 cells
Keywords: AD; Alzheimer's disease; ALP; autophagy-lysosome pathway; APP; amyloid precursor protein; ATG; autophagy-related gene; AVs; autophagic vacuoles; Aβ; β-amyloid peptide; DPA; dehydropachymic acid; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; GSK-3; Gl
In vivo effects of metal ions on conformation and mechanical performance of silkworm silks
Keywords: ASG; anterior silk gland; CD; circular dichroism; CDS; coding sequence; EST; expressed sequence tag; FTIR; Fourier-transform infrared spectroscopy; ICP-AAS; inductively coupled plasma atomic absorption spectroscopy; MSG; middle silk gland; NCBI; National
Bafilomycin analogue site-specifically fluorinated at the pharmacophore macrolactone ring has potent vacuolar-type ATPase inhibitory activity
Keywords: Fluorine-label; Chemical synthesis; V-ATPase; Bafilomycin; Conformational analysis;
The F-actin modulator SWAP-70 controls podosome patterning in osteoclasts
Keywords: Actin cytoskeleton; Podosome pattering; Membrane binding; PIP3; Swap-70; V-ATPase
Ammonia excretion in Caenorhabditis elegans: Physiological and molecular characterization of the rhr-2 knock-out mutant
Keywords: Rh-proteins; Na+/K+-ATPase; V-ATPase; NHX-3; Ammonia trapping
Dot1l deficiency leads to increased intercalated cells and upregulation of V-ATPase B1 in mice
Keywords: V-ATPase; Histone methyltransferase Dot1l; Conditional knockout; Principal cells; Intercalated cells
MDM2 antagonist nutlin-3a sensitizes tumors to V-ATPase inhibition
Keywords: Cancer; Therapy; p53; V-ATPase; Nutlin-3a; V-ATPase; vacuolar-type ATPase; OXPHOS; oxidative phosphorylation; TIGAR; TP53-induced glycolysis and apoptosis regulator; U87; U87MG; IGFBP3; insulin-like growth factor-binding protein 3;
Adipose tissue (P)RR regulates insulin sensitivity, fat mass and body weight
Keywords: (Pro)renin receptor; Renin-angiotensin system; Adipose tissue knock-out mice; Obesity; Adipose tissue; Insulin resistance; ANG; Angiotensin; BAT; brown adipose tissue; BB; beam break; HACT; horizontal activity; HFD; high-fat diet; HRP; handle-region pepti
Biological characterization of the hygrobafilomycin antibiotic JBIR-100 and bioinformatic insights into the hygrolide family of natural products
Keywords: DiOC2(3); 3,3â²-diethyloxacarbocyanine iodide; ACP; acyl carrier protein; AT; acyltransferase; BGC; biosynthetic gene cluster; CCDC; Cambridge Crystallographic Data Centre; CID; collision-induced dissociation; DIC; differential interference contrast; DTT
Disorders of lysosomal acidification-The emerging role of v-ATPase in aging and neurodegenerative disease
Keywords: Lysosome; Acidification; pH; v-ATPase; Endocytosis; Autophagy; Lysosomal storage disease; Alzheimer's disease; Parkinson's disease; mTORC; Calcium; TFEB; Cathepsin; Caloric restriction;
Leucine induced dephosphorylation of Sestrin2 promotes mTORC1 activation
Keywords: 4E-BP1; eukaryotic initiation factor 4E binding protein 1; AMPK; AMP-activated protein kinase; Atg13; autophagy-related 13; FIP200; 200Â kilodalton focal adhesion kinase family kinase-interacting protein; GAP; GTPase activator protein; GATOR; GAP activity
Synthesis and structure-activity studies of the V-ATPase inhibitor saliphenylhalamide (SaliPhe) and simplified analogs
Keywords: V-ATPase; Antiviral; Anticancer; Benzolactone; Salicylihalamide;
Phosphorylation control of protein tyrosine phosphatase A activity in Mycobacterium tuberculosis
Keywords: Mtb; Mycobacterium tuberculosis; TB; tuberculosis; PtkA; protein tyrosine kinase A; PtpA; protein tyrosine phosphatase A; PknA; protein kinase A; VPS33B; vacuolar protein sorting 33B; V-ATPase; vacuolar H+-ATPase; SDM; site-directed mutagenesis; Protein t
A cyclohexadepsipeptide from entomogenous fungi Metarhizium anisopliae inhibits the Helicobacter pylori induced pathogenesis through attenuation of vacuolating cytotoxin-A activity
Keywords: Destruxin B; Helicobacter pylori; Vacuolating cytotoxin A; V-ATPase
The effects of JM-20 on the glutamatergic system in synaptic vesicles, synaptosomes and neural cells cultured from rat brain
Keywords: JM-20; Glutamatergic system; Synaptic vesicle; Synaptosomes; Astrocytes; Neurons; VGLUTs; vesicular glutamate transporters; V-ATPase; vacuolar-type ATPases; JM-20; 3-ethoxycarbonyl-2-methyl-4-(2-nitrophenyl)-4,11-dihydro-1H-pyrido[2,3-b][1,5]benzodiazepin
Role of vacuolar-type proton ATPase in signal transduction
Keywords: V-ATPase; Wnt; mTOR; Notch; Signaling pathway;
Proton-dependent glutamine uptake by aphid bacteriocyte amino acid transporter ApGLNT1
Keywords: AAAP; amino acid/auxin permease; APC; amino acid-polyamine-organocation; ApGLNT1; Acyrthosiphon pisum glutamine transporter 1; PAT; proton-dependent amino acid transporter; SLC; solute carrier; TEVC; two-electrode voltage clamp; V-ATPase; vacuolar-typ
Predominant expression and activity of vacuolar H+-ATPases in the mixed segment of the wood-feeding termite Nasutitermes takasagoensis
Keywords: Transcriptome; Termite; Mixed segment; V-ATPase; Gut