Keywords: MAP1LC3; microtubule-associated protein 1 light chain 3; LAMP1; lysosomes associated membrane protein 1; ROS; reactive oxygen species; EGCG; epigallocatechin gallate; CCCP; carbonyl cyanide 3-chlorophenylhydrazone; VDAC1; voltage-dependent anion-selective
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Keywords: Mitochondria; Proteomics; Mass spectrometry; Cancer; 1DE; one-dimensional gel electrophoresis; 2DE; two-dimensional gel electrophoresis; 2D-DIGE; fluorescent two-dimensional difference gel electrophoresis; AP; affinity purification; ACAT1; mitochondrial a
Keywords: AD; Alzheimer's disease; BBB; blood brain barrier; RAGE; Receptor for Advanced Glycation End products; AGE; advanced glycation end products; IL1β; interleukin 1 beta; Aβ; amyloid beta; TNF â;  tumor necrosis factor alpha; TGFβ; transforming growth
Keywords: DCFH-DA; 2â²,7â²-Dichlorodihydrofluorescein diacetate; CCCP; carbonyl cyanide m-chlorophenylhydrazone; AMPK; AMP-activated protein kinase; PGC1; Peroxisome proliferator-activated receptor gamma coactivator 1; NOX4; NADPH oxidase 4; SOD2; manganese-depen
Keywords: AB; Apoptotic body; ADP; Adenosine diphosphate; Anx; Annexin; ASARM; Acidic serine- and aspartate-rich motif; ATP; Adenosine triphosphate; BMP; Bone morphogenetic protein; CK; Choline kinase; CKD; Chronic kidney disease; ECM; Extracellular matrix; GPI; Gl
Keywords: 1,25(OH)2D; 1,25 dihydroxy vitamin D (calcitriol); 3βHSD; 3β-hydroxysteroid dehydrogenase; ACAT; acyl transferase; ACTH; adrenocorticotropic hormone; ANT; adenine nucleotide transporter; ER; endoplasmic reticulum; CRAC; cholesterol recognition amino aci
Sennoside A protects mitochondrial structure and function to improve high-fat diet-induced hepatic steatosis by targeting VDAC1
Keywords: Mitochondria; Hepatic steatosis; Sennoside A; VDAC1; Complex I; ATP;
Mitophagy is activated in brain damage induced by cerebral ischemia and reperfusion via the PINK1/Parkin/p62 signalling pathway
Keywords: PINK1; PTEN-induced kinase 1; i.p.; intraperitoneal; CCA; common carotid artery; ECA; external carotid artery; ICA; internal carotid artery; MCAO; middle cerebral artery occlusion; H&E; haematoxylin and eosin; LC3; Microtubule-associated protein 1 light c
Targeting Liver Cancer and Associated Pathologies in Mice with a Mitochondrial VDAC1-Based Peptide
Keywords: VDAC1; voltage-dependent anion channel 1; HK; hexokinase; Cyto c; cytochrome c; DEN; diethylnitrosamine; HCC; hepatocellular carcinoma; HFD; high fat diet; AIF; apoptosis-inducing factor; LDH; lactate dehydrogenase; NASH; nonalcoholic steatohepatitis; TfR
Labelling proteins and peptides with phosphorescent d6 transition metal complexes
Keywords: Aβ; amyloid-β; BRD4; bromodomain-containing protein 4; BSA; bovine serum albumin; COX-2; cyclooxygenase-2; D/P; dye:protein ratio, used to quantify the number of metal complexes attached per protein; DNA; deoxyribonucleic acid; EC50; half maximal effect
TDP-43 interacts with mitochondrial proteins critical for mitophagy and mitochondrial dynamics
Keywords: APP; amyloid precursor protein; VDAC1; voltage dependent anion channel 1; TDP-43; TAR DNA binding protein of 43â¯kDa; PSEN1/PS1; presenilin 1; AD; Alzheimer disease; hnRNP; heterogeneous nuclear ribonucleoprotein; ALS; amyotrophic lateral sclerosis; MND;
WDR26/MIP2 interacts with VDAC1 and regulates VDAC1 expression levels in H9c2 cells
Keywords: MIP2; VDAC1; Protein-protein interaction; Apoptosis; Mitochondria;
Artesunate-induced mitophagy alters cellular redox status
Keywords: ACADVL; very long-chain specific acyl-CoA dehydrogenase; ACC; acetyl-CoA carboxylase 1; ATP; adenosine triphosphate, vacuolar-type H+-ATPase (V-ATPase); COX â
£; cytochrome c oxidase IV; CPS; carbamoyl-phosphate synthase; CQ; chloroquine; GSH; glutathione
VDAC1 deacetylation is involved in the protective effects of resveratrol against mitochondria-mediated apoptosis in cardiomyocytes subjected to anoxia/reoxygenation injury
Keywords: Resveratrol; VDAC1; Acetylation; Silent information regulator of transcription 1; Anoxia/reoxygenation; Cardiomyocytes;
Mangiferin protects mitochondrial function by preserving mitochondrial hexokinase-II in vessel endothelial cells
Keywords: ACh; acetylcholine; CAC; citric acid cycle; DHE; dihydroethidium; FFAs; free fatty acids; HFD; high-fat diet; HIF-1α; hypoxic inducible factor-1α; HK; hexokinase; HUVECs; human umbilical vein endothelial cells; mPTP; mitochondrial permeability transitio
Influence of the APOE genotype on hepatic stress response: Studies in APOE targeted replacement mice and human liver cells
Keywords: AD; Alzheimer's disease; APOE; apolipoprotein E; ATP; adenosine triphosphate; ATP5A1; ATP synthase subunit alpha, mitochondrial; B2M; beta-2 microglobulin; BAX; BCL2-associated X protein; BCL2; B-cell leukemia/lymphoma 2; BiP; binding immunoglobulin prote
Epigallocatechin gallate and mitochondria-A story of life and death
Keywords: ADP; adenosine diphosphate; AIF; apoptosis-inducing factor; ALT; alanine aminotransferase; AMP; adenosine monophosphate; AP-1; activator protein-1; ASK1; apoptosis signal-regulating kinase 1; ATP; adenosine triphosphate; Bax; BCL2-Associated X Protein; Bc
VDAC1-interacting anion transport inhibitors inhibit VDAC1 oligomerization and apoptosis
Keywords: Anion transport inhibitors; Apoptosis; Oligomerization; Mitochondria; VDAC1;
Reducing VDAC1 expression induces a non-apoptotic role for pro-apoptotic proteins in cancer cell differentiation
Keywords: Apoptosis; Cell differentiation; Glioblastoma; Metabolism; Mitochondria; VDAC1;
ER functions of oncogenes and tumor suppressors: Modulators of intracellular Ca2Â + signaling
Keywords: a.a.; amino acid; ATP; adenosine triphosphate; BH domain; Bcl-2-homology domain; BI-1; Bax inhibitor-1; BIRD-2; Bcl-2/IP3R disruptor-2; BRCA1; breast and ovarian cancer susceptibility gene 1; [Ca2Â +]cyt; cytosolic Ca2Â + concentration; CLL; chronic lymph
Disruption of the human COQ5-containing protein complex is associated with diminished coenzyme Q10 levels under two different conditions of mitochondrial energy deficiency
Keywords: 2D BN-PAGE; two-dimensional blue native-polyacrylamide gel electrophoresis; BHA; butylated hydroxyanisole; CoQ; coenzyme Q; FCCP; carbonyl cyanide-p-trifluoromethoxyphenylhydrazone; HPLC; high-performance liquid chromatography; m-COQ5; mature form of COQ5
Vorinostat synergizes with EGFR inhibitors in NSCLC cells by increasing ROS via up-regulation of the major mitochondrial porin VDAC1 and modulation of the c-Myc-NRF2-KEAP1 pathway
Keywords: AREs; Antioxidant response elements; CI; Combination index; DRI; Dose reduction index; EGFR; Epidermal growth factor receptor; EMT; Epithelial-to-mesenchymal transition; GSK3β; Glycogen synthase kinase 3β; HDACi; Histone deacetylase inhibitor; HK1; Hexo
The mitochondrial voltage-dependent anion channel 1 in tumor cells
Keywords: Apoptosis; Cancer; Mitochondria; Metabolism; VDAC1
Organelle communication: Signaling crossroads between homeostasis and disease
Keywords: Organelles; Endoplasmic reticulum; Mitochondria; Calcium signaling; BNIP1; BCL2/adenovirus E1B interacting protein 1; Ca2+; calcium; CERT; ceramide transfer protein; CMT2A; Charcot-Marie-Tooth type 2A; ÎÏmt; mitochondrial transmembrane potential; Dr
Analysis of subcellular [57Co] cobalamin distribution in SH-SY5Y neurons and brain tissue
Keywords: AdoCbl; adenosyl cobalamin; Cbl; cobalamin; Hcy; homocysteine; LAMP2; lysosomal-associated membrane protein 2; LER; Lysosome Enrichment Reagent; Met; methionine; MS; methionine synthase; MeCbl; methyl Cbl; MMCM; methylmalonyl-coenzyme A mutase; 5-methyl-T
The role of calcium in VDAC1 oligomerization and mitochondria-mediated apoptosis
Keywords: Cyto c; cytochrome c; EGS; ethylene glycol bis[succinimidylsuccinate]; OMM; outer mitochondrial membrane; PLB; planar lipid bilayer; RuR; Ruthenium red; STS; staurosporine; VDAC; voltage-dependent anion channel; Apoptosis; Ca2Â +; Mitochondria; Oligomeriz
TMEM126A is a mitochondrial located mRNA (MLR) protein of the mitochondrial inner membrane
Keywords: HON; hereditary optic neuropathy; RGC; retinal ganglion cell; mtDNA; mitochondrial DNA; LHON; Leber's Hereditary Optic Neuropathy; OPA; optic atrophy; TMEM126A; transmembrane protein 126A; IMS; intermembrane space; OM; outer membrane; IM; inner membrane;
Visualization and quantification of cardiac mitochondrial protein clusters with STED microscopy
Keywords: STED; STimulated Emission Depletion; VDAC1; Voltage Dependent Anion Channel 1; Cox2; Cytochrome c Oxidase subunit 2; SFKs; Src family of tyrosine kinases; PPI; protein proximity index; FWHM; Full Width Half Maximum; TDE; 2,2â²-Thiodiethanol; STED; Mitoch
Emerging role of p62/sequestosome-1 in the pathogenesis of Alzheimer's disease
Keywords: AD; Alzheimer's disease; AKT; protein kinase B; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate receptor; aPKC; atypical protein kinase C; APP; amyloid-β precursor protein; ATG; AuTophaGy-related; BDNF; brain-derived neurotrophic factor; C/EBP; C
Proteomic analysis of lipid raft-enriched membranes isolated from internal organelles
Keywords: DRMs; detergent-resistant membranes; ETC; electron transport chain; ER; endoplasmic reticulum; IP3R3; inositol 1,4,5-trisphosphate receptor type 3; LRs; lipid rafts; MAM; mitochondria-associated ER membrane; MS/MS; tandem mass spectrometry; PM; plasma mem
Molecular model of hexokinase binding to the outer mitochondrial membrane porin (VDAC1): Implication for the design of new cancer therapies
Keywords: Hexokinase; VDAC1; Mitochondrial outer membrane permeabilization; Protein modeling; Docking simulations; Apoptosis; Cancer;
p32 regulates mitochondrial morphology and dynamics through parkin
Keywords: parkin; Parkinson's disease; mitochondria; neurodegeneration; autophagy; ARJP; autosomal recessive juvenile form of Parkinsonism; DAPI; 4â²-6-Diamidino-2-phenylindole; FPD; familial Parkinson's disease; GST-NPK; GST-tagged N-terminal parkin fragment; Mfn
Lipid peroxidation and neurodegenerative disease
Keywords: Aβ; amyloid-β peptide; ALDO1; aldolase; AD; Alzheimer disease; ALS; amyotrophic lateral sclerosis; APP; amyloid precursor protein; BDNF; brain-derived neurotrophic factor; CK; creatine kinase; CR1; carbonyl reductase; CSF; cerebrospinal fluid; DHA; doco
Phosphorylation by Nek1 regulates opening and closing of voltage dependent anion channel 1
Keywords: Nek1; VDAC1; Apoptosis; Atomic force microscopeAFM, atomic force microscopy; DTT, dithiothreitol; EDTA, ethylenediaminetetraacetic acid; GST, glutathione S-transferase; Nek1, never-in-mitosis A related kinase 1; PBS, phosphate buffered saline; SBP, strept
Voltage-dependent anion-selective channel 1 (VDAC1)-a mitochondrial protein, rediscovered as a novel enzyme in the plasma membrane
Keywords: VDAC1; Plasma membrane NADH; Ferricyanide reductase; Redox homeostasis; Apoptosis;