دانلود مقالات ISI درباره Vdss + ترجمه فارسی

کشف یک آنتاگونیست پپتید 1 با گلوکاگون طولانی مدت با تمایل تجمع افزایش یافته

Discovery of a long-acting glucagon-like peptide-1 analog with enhanced aggregation propensity

Keywords: ABD3; albumin-binding domain 3; ACN; acetonitrile; AUC; area under the curve; BA; bioavailability; cAMP; cyclic adenosine monophosphate; CHO; Chinese hamster ovary; DIEA; diisopropyl ethylene diamine; Cmax; peak plasma concentration; CLp; plasma clearance

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2018 سفارش ترجمه

طراحی، سنتز و ارزیابی بیولوژیکی مهار کننده های رنین با هدایت شبیه سازی شده شبیه سازی شبیه سازی پتانسیل شیمیایی

Design, synthesis and biological evaluation of renin inhibitors guided by simulated annealing of chemical potential simulations

Keywords: SACP; simulated annealing of chemical potential; CFA; constrained fragment analysis; FE Pred; predicted relative free energy; ΔΔGs; relative solvation change; D5W; 5% dextrose (glucose) in water; Vdss; steady-state volume of distribution; Cl; clearance;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2017 سفارش ترجمه

در جنوب تبت، ضخیم تر به نظر می رسد

Weakly coupled lithospheric extension in southern Tibet

Keywords: Tibetan plateau; E-W extension; N-S trending rift; VDSS; crustal structure;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Safety, immunogenicity, and clinical outcomes in patients with Morquio A syndrome participating in 2 sequential open-label studies of elosulfase alfa enzyme replacement therapy (MOR-002/MOR-100), representing 5 years of treatment

Keywords: Morquio A; Mucopolysaccharidosis IVA; Long-term extension; Elosulfase alfa; 3MSCT; 3-min stair climb test; 6MWT; 6-min walk test; AE; adverse event; AUC0−t; area under the curve from time 0 to last measurable concentration; AUCinf; area under the curve

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Synthesis and profiling of benzylmorpholine 1,2,4,5-tetraoxane analogue N205: Towards tetraoxane scaffolds with potential for single dose cure of malaria

Keywords: AUC; area under the curve; BA; bioavailability; CLplasma; plasma clearance; CLint; intrinsic clearance; CYP; cytochrome P450; DCM; dichloromethane; DMF; dimethyl formamide; ED; effective dose; FaSSIF; fasted state simulated intestinal fluid; FeSSIF; fed s

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2018 سفارش ترجمه

Evaluating the intestinal and oral absorption of the prodrug valacyclovir in wildtype and huPepT1 transgenic mice

Keywords: ACV; Acyclovir; AUC0-180; Area under the plasma concentration-time curve from 0 to 180 min; CL; Clearance; Cmax; Maximum plasma concentration; F; Bioavailability; Gly-Sar; glycylsarcosine; huPepT1; Humanized peptide transporter 1; Inu; Inulin; Km; Micha

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2018 سفارش ترجمه

A PEGylated analog of short-length Neuromedin U with potent anorectic and anti-obesity effects

Keywords: Neuromedin U (NMU); NMU-8; Polyethylene glycol (PEG); Diabetes; Obesity; NMU; neuromedin U; PEG; polyethyleneglycol; PipAc; 2-(piperazin-1-yl)acetic acid; CNS; central nervous system; DIO; diet-induced obesity; EMCS; N-(6-maleimidocaproyloxy)succinimide;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2017 سفارش ترجمه

Studies of CDK 8/19 inhibitors: Discovery of novel and selective CDK8/19 dual inhibitors and elimination of their CYP3A4 time-dependent inhibition potential

Keywords: ADME; absorption, distribution, metabolism, and excretion; AML; acute myelogenous leukemia; AUC; area under the blood concentration time curve; b.i.d.; twice a day; CDK; Cyclin-dependent kinase; CLtotal; clearance; Cmax; maximum drug concentration; CRC; c

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2017 سفارش ترجمه

Simulations of Cytochrome P450 3A4-Mediated Drug-Drug Interactions by Simple Two-Compartment Model-Assisted Static Method

Keywords: bioavailability; cytochrome P450; drug interaction; dynamic simulation; first pass metabolism; hepatic clearance; intestinal metabolism; pharmacokinetics; simulations; parallel tube model; Ae (Ae,oral); dose fractions of urinary excreted unchanged drug af

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2017 سفارش ترجمه

Pharmacokinetics of Intravenous Lorazepam in Pediatric Patients with and without Status Epilepticus

Keywords: CL; Clearance; Vdss; Steady state volume of distribution; ED; Emergency department; NC; Non-compartmental; SE; Status epilepticus; T1/2; Half-life; T1/2 Beta; Elimination half-life;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Immunopharmacotherapeutic manifolds and modulation of cocaine overdose

Keywords: mAb; monoclonal antibody; IgG; immunoglobulin G; Fab; Fab antibody fragment; scFv; single-chain antibody fragment; VH and VL; antibody heavy- and light-chain variable domains; GNC-BSA; GNC hapten conjugated to bovine serum albumin carrier protein; i.v.;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Discovery of potent, efficacious, and orally bioavailable inhibitors of blood coagulation factor Xa with neutral P1 moieties

Keywords: Blood coagulation; Factor Xa; Thrombin, trypsin; Selectivity; BMS-740808; Aminobenzisoxazole; P-methoxyphenyl and 3-phenylcarboxamido P1; Dog ‘N-in-one’ pharmacokinetics; Oral bioavailability; Clearance; Vdss; Half-life; Rabbit AV Shunt efficacy

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2006 سفارش ترجمه