دانلود مقالات ISI درباره WT، نوع وحشی + ترجمه فارسی

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Dynamic expression of nectins in enamel organs of mouse incisors

Keywords: WT، نوع وحشی; Ameloblast; Cell adhesion; Enamel organ; Mice; Nectin; AJ, adherens junction; H-E, hematoxylin and eosin; KO, deficient; micro-CT, micro-computed tomography; M1, first molar; qRT-PCR, quantitative reverse transcription-PCR; SI, stratum intermedium; WT, wi

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

تشخیص بازدارنده های مونوآسیلیک گلیسرول آتیل ترانسفراز 2 توسط یک پروب جدید در آزمایش های اتصال

Characterization of monoacylglycerol acyltransferase 2 inhibitors by a novel probe in binding assays

Keywords: WT، نوع وحشی; MGAT2; Enzyme inhibitor binding assay; Enzyme inhibitor kinetics; Acyltransferase; Triglyceride synthesisMGAT2, monoacylglycerol acyltransferase 2; TG, triacylglycerol; KO, knockout; WT, wild-type; SAR, structure–activity relationship; DGAT1, diacylglycer

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

دو پروتئین جعبه ای گروهی از دو گروه تقسیم مجدد مخمر در حفظ یکپارچگی ژنوم به دنبال توهین دکسوروبیسین

Two fission yeast high mobility group box proteins in the maintenance of genomic integrity following doxorubicin insult

Keywords: WT، نوع وحشی; DXR, doxorubicin resistance; HMG, high mobility group; WT, wild-type; HR, homologous recombinationDoxorubicin; Drug resistance; High mobility group; Rhp54; Hap2; Nht1; Fission yeast; S. pombe

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

بررسی نقش آمینو اسیدها در واکنش اکسیم توسط عامل عصبی - استیل کولین استراز انسانی مهار شده

Probing the role of amino acids in oxime-mediated reactivation of nerve agent-inhibited human acetylcholinesterase

Keywords: WT، نوع وحشی; ACh, acetylcholine; AChE, acetylcholinesterase; rHu AChE, recombinant human acetylcholinesterase; WT, wild-type; OP, organophosphorus compounds; GA, tabun; GB, sarin; GD, soman; GF, cyclosarin; VX, O-ethyl-S-[2-(diisopropylamino) ethyl] methyl phosphonoth

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

یک موتیف دم جدید سیتوپلاسمی تنظیم بیان موش سوری بر روی سطح سلول را تنظیم می کند

A novel cytoplasmic tail motif regulates mouse corin expression on the cell surface

Keywords: WT، نوع وحشی; Corin; Cytoplasmic tail; Intracellular trafficking; Natriuretic peptides; Transmembrane proteasesFBS, fetal bovine serum; HEK, human embryonic kidney; TTSP, type II transmembrane serine protease; WT, wild-type

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

توصیف جنبشی تیروپروکسیداز انسانی. بیان عصاره و آنزیم پاتولوژیک در سیستم باکولو ویروس: یک مدل مولکولی از بیان عملکردی

Kinetic characterization of human thyroperoxidase. Normal and pathological enzyme expression in Baculovirus System: A molecular model of functional expression

Keywords: WT، نوع وحشی; hTPO, human thyroperoxidase gene (according to the recommendations of the HUGO Gene Nomenclature Committee) and protein; TG, thyroglobulin; IOD, iodine organification defects; WT, wild-type; EGF, epidermal growth factor; RT-PCR, reverse transcription poly

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

عملکرد و ساختار تجزیه و تحلیل یک تعویض آسپارتات از گلیسین ثابت در مارپیچ دامنه α1-α1، اینتگرین βI

Function and conformation analyses of an aspartate substitution of the invariant glycine in the integrin βI domain α1-α1′ helix

Keywords: WT، نوع وحشی; EGTA, ethylene glycol tetra-acetic acid; WT, wild-type; NOE, Nuclear Overhauser Effect; I-EGF, Integrin-Epidermal Growth Factor; HEK, Human Embryonic Kidney; Asp, Aspartic Acid; Gly, Glycine.Mutation; Integrin activation; Ligand binding; NMR; Conformation

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

بیان ژن تطبیقی و تحلیل فنوتیپ عضله اسکلتی از موش های بالغ نوع وحشی با اختلال PAPP-A

Comparative gene expression and phenotype analyses of skeletal muscle from aged wild-type and PAPP-A-deficient mice

Keywords: WT، نوع وحشی; PAPP-A, pregnancy-associated plasma protein-A; WT, wild-type; KO, knock-out; IGF, insulin-like growth factor; CSA, cross-sectional area; mtDNA, mitochondrial DNAPregnancy-associated plasma protein-A; Soleus; Mitochondria

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Mutation of the key residue for extraribosomal function of ribosomal protein S19 cause increased grooming behaviors in mice

Keywords: WT، نوع وحشی; ANOVA, analysis of variance; CNS, central nervous system; RP S19, ribosomal protein S19; KI, knock-in; WT, wild-type; Gln, glutamine; Glu, glutamic acid; C5a, complement 5aAnxiety-like behavior; Complement system; Extraribosomal function; Fear memory; Gro

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Influence of cAMP receptor protein (CRP) on bacterial virulence and transcriptional regulation of allS by CRP in Klebsiella pneumoniae

Keywords: WT، نوع وحشی; CRP, cAMP receptor protein; K. pneumoniae, Klebsiella pneumoniae; WT, wild-type; Kp-Δcrp, crp knockout; KpC-Δcrp, the complemented knockout; E. coli, Escherichia coli; K2044, wild-type Klebsiella pneumoniae NTUH-K2044; KO, knockout; EMSA, electrophoretic

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Myopathy-causing Q147P TPM2 mutation shifts tropomyosin strands further towards the open position and increases the proportion of strong-binding cross-bridges during the ATPase cycle

Keywords: WT، نوع وحشی; TM, Tropomyosin; WT, Wild-type; S1, Myosin subfragment-1; FITC-phalloidin, Phalloidin-fluorescein isothiocyanate; 1,5-IAEDANS, N-(iodoacetaminoethyl)-1-naphthyl-amine-5-sulfonic acid; 5-IAF, 5-iodoacetamidofluorescein; SDS − PAGE, Polyacrylamide gel elect

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Cellular signalling of cysteinyl leukotriene type 1 receptor variants CysLT1-G300S and CysLT1-I206S

Keywords: WT، نوع وحشی; cysLTs, cysteinyl-leukotrienes; CysLT1, cysteinyl-leukotriene type 1 receptor; WT, wild-type; LT, leukotriene; GPCR, G-protein-coupled receptorCysteinyl-leukotriene; CysLT1; Variant; Signalling; Atopy

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

TNFα reduces eNOS activity in endothelial cells through serine 116 phosphorylation and Pin1 binding: Confirmation of a direct, inhibitory interaction of Pin1 with eNOS

Keywords: WT، نوع وحشی; eNOS, Endothelial nitric oxide synthase; BAECs, Bovine aortic endothelial cells; FL, Full-length; BSA, Bovine serum albumin; Ad, Adenovirus; WT, Wild-type; ß-gal, ß-galactosidaseEndothelial nitric oxide synthase (eNOS); Pin1; TNFα

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Splice variant insertions in the C-terminus impairs YAP’s transactivation domain

Keywords: WT، نوع وحشی; YAP, yes-associated protein; TAD, transcriptional activation domain; hYAP:, human YAP; aa:, Amino acid; mYAP:, mouse YAP; WT, wild-type; Con, control; EV, empty vectorYes-associated protein (YAP); Alternate splicing; Transcriptional co-activator; Lucifera

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

DRME: Count-based differential RNA methylation analysis at small sample size scenario

Keywords: WT، نوع وحشی; N6-Methyladenosine (m6A); RNA methylation; MeRIP-Seq; Differential methylation; R/Bioconductor package; Negative binomial distributionK/O, knockout; WT, wild-type; DAA, 3-deazaadenosine; GEO, Gene Expression Omnibus; m6A, N6-methyladenosine; FTO, Fat mass

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Fasudil, a Rho kinase inhibitor, promotes the autophagic degradation of A53T α-synuclein by activating the JNK 1/Bcl-2/beclin 1 pathway

Keywords: WT، نوع وحشی; α-syn, α-synuclein; PD, Parkinson׳s disease; ROCK, Rho kinase; WT, wild-type; LBs, Lewy bodies; UPS, ubiquitin proteasome system; BSA, bovine serum albumin; CMA, chaperone-mediated autophagy; 3-MA, 3-methyladenine; Co-IP, Co-Immunoprecipitation; TEM, Tran

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Functional and transcriptomic analysis of the key unfolded protein response transcription factor HacA in Aspergillus oryzae

Keywords: WT، نوع وحشی; UPR, unfolded protein response; HacA-DE, a homokaryotic hacA disruption mutant; HacA-CA, a strain that expressed a constitutively active form of HacA; WT, wild-type; ER, endoplasmic reticulum; bZIP, the basic leucine zipper; ERAD, ER-associated degradatio

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Characterization of novel cytochrome P450 2E1 knockout rat model generated by CRISPR/Cas9

Keywords: WT، نوع وحشی; Chlorzoxazone (PubChem CID: 2733); 3-Acetamidophenol (PubChem CID: 12124); 6-Hydroxychlorzoxazone (PubChem CID: 2734)CYP, cytochrome P450; KO, knockout; WT, wild-type; ZFNs, zinc-finger nucleases; TALENs, transcription activator-like effector nucleases; C

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

The Termination Phase in Protein Synthesis is not Obligatorily Followed by the RRF/EF-G-Dependent Recycling Phase

Keywords: WT، نوع وحشی; RRF, ribosomal recycling factor; Rluc, Renilla luciferase; Fluc, firefly luciferase; SD, Shine–Dalgarno; RRFts, temperature-sensitive RRF; WT, wild-type; Pth, peptidylhydrolase; Pthts, temperature-sensitive Pthprotein synthesis; termination of protein syn

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Overexpression of CHMP7 from rapeseed and Arabidopsis causes dwarfism and premature senescence in Arabidopsis

Keywords: WT، نوع وحشی; ESCRT, endosomal sorting complexes required for transport; MVB, multi-vesicular body; CHMP7, charged multi-vesicular body protein 7; VPS, vacuolar protein sorting; SNF7, sucrose non-fermenting 7; WT, wild-type; BiFC, bifluorescence complementation; CLSM,

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Design and synthesis of a C7-aryl piperlongumine derivative with potent antimicrotubule and mutant p53-reactivating properties

Keywords: WT، نوع وحشی; Hybrid drugs; Oxidative stress; Combretastatin-A4; Protein glutathionylation; Cancer chemotherapyROS, reactive oxygen species; GSH, glutathione; CA4, combretastatin A4; PL, piperlongumine; wt, wild-type; DCF-DA, 2′,7′-dichlorofluorescein diacetate; KSS-9,

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Resolution of Specific Nucleotide Mismatches by Wild-Type and AZT-Resistant Reverse Transcriptases during HIV-1 Replication

Keywords: WT، نوع وحشی; RT, reverse transcriptase; WT, wild-type; AZTR, AZT-resistant; RIO, retroviral inside-out; LTR, long terminal repeat; ppt, polypurine tract; RSV, Rous sarcoma virus; PBS, primer binding site; RRE, Rev response elementretroviral error mechanisms; forced co

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Walker-A Motif Acts to Coordinate ATP Hydrolysis with Motor Output in Viral DNA Packaging

Keywords: WT، نوع وحشی; IHF, integration host factor; WT, wild-type; CD, circular dichroism; SV-AUC, sedimentation velocity analytical ultracentrifugation; DC, defective coupling; SA, streptavidinviral DNA packaging motor; terminase; Optical tweezers; ATPase; mutagenesis of Walk

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2016 سفارش ترجمه

Identification of E545k mutation in plasma from a PIK3CA wild-type metastatic breast cancer patient by array-based digital polymerase chain reaction: Circulating-free DNA a powerful tool for biomarker testing in advance disease

Keywords: WT، نوع وحشی; cfDNA, circulating-free DNA; dPCR, digital polymerase chain reaction; ER, estrogen receptor; PR, progesterone receptor; wt, wild-type

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Functional analyses of carnivorous plant-specific amino acid residues in S-like ribonucleases

Keywords: WT، نوع وحشی; Carnivorous plants; Drosera adelae; kcat/Km; Protein structure; S-like ribonucleaseCAS, conserved active site; QS, quadruple substitution; 3D, three dimension(al); Wt, wild-type

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Characterization of single amino acid substitutions in the β2 integrin subunit of patients with leukocyte adhesion deficiency (LAD)-1

Keywords: WT، نوع وحشی; LAD-1, Leukocyte adhesion deficiency-1; LFA-1, Leukocyte function associated antigen-1 (αLβ2); Mac-1, Macrophage antigen-1 (αMβ2); ICAM, Intercellular adhesion molecule; BSA, Bovine serum albumin; WT, Wild-type; NMR, Nuclear magnetic resonanceLAD-1; Misse

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Muscle spindles exhibit core lesions and extensive degeneration of intrafusal fibers in the Ryr1I4895T/wt mouse model of core myopathy

Keywords: WT، نوع وحشی; Core myopathy; Ryanodine receptor type 1; Muscle spindle; Intrafusal fibers; Muscle weakness; Mouse modelCCD, central core disease; MmD, multiminicore disease; NM, nemaline rod myopathy; RyR1, ryanodine receptor type 1; TB, toluidine blue; WT, wild-type

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Adaptive mutation PB2 D701N promotes nuclear import of influenza vRNPs in mammalian cells

Keywords: WT، نوع وحشی; CHX, cycloheximide; LMB, leptomycin B; NLS, nuclear localisation signal; NP, nucleoprotein; TPCK, tosyl phenylalanyl chloromethyl ketone; vRNP, viral ribonucleoprotein; WT, wild-type; w/o, withoutInfluenza virus; Nuclear import; PB2

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Should diffuse bronchiectasis still be considered a CFTR-related disorder?

Keywords: WT، نوع وحشی; CFTR, cystic fibrosis transmembrane conductance regulator; CF, cystic fibrosis; CFTR-RD, CFTR-related disorder; DB, diffuse bronchiectasis; WT, wild-type; IQR, interquartile range; M, mild; UV, unclassified variant; P, rare polymorphism; NNV, non-neutral

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

The dopamine D3 receptor regulates the effects of methamphetamine on LPS-induced cytokine production in murine mast cells

Keywords: WT، نوع وحشی; METH, methamphetamine; HIV, human immunodeficiency virus; D3R, dopamine D3 receptor; DA, dopamine; LPS, lipopolysaccharide; TNF-a, tumour necrosis factor; TLR4, Toll-like receptor 4; NSn, ormal saline; BMMC, bone marrow-derived mast cells; WT, wild-type;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

MicroRNAs are implicated in the suppression of CD4+CD25− conventional T cell proliferation by CD4+CD25+ regulatory T cells

Keywords: WT، نوع وحشی; Tregs, CD4+CD25+ regulatory T cells; Tcons, CD4+CD25− conventional T cells; miRNA, microRNA; WT, wild-type; GFP-Tg, green fluorescent protein transgenic; mAbs, monoclonal antibodies; PBS, phosphate-buffered saline; PI, propidium iodide; FCM, flow cytometr

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Involvement of mortalin/GRP75/mthsp70 in the mitochondrial impairments induced by A53T mutant α-synuclein

Keywords: WT، نوع وحشی; α-syn, α-synuclein; PD, Parkinson׳s disease; SNpc, the substantia nigra pars compacta; ROS, reactive oxygen species; WT, wild-type; mthsp70, mitochondrial chaperone of the heat shock protein 70; GRP75, glucose-regulated protein 75; AD, Alzheimer׳s disease

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

The role of alpha5 nicotinic acetylcholine receptors in mouse models of chronic inflammatory and neuropathic pain

Keywords: WT، نوع وحشی; nAChRs, nicotinic acetylcholine receptors; CCI, chronic constriction nerve injury; PWL, paw withdrawal latency; CFA, complete Freund's adjuvant; KO, knock-out; WT, wild-type; TNF-α, tumor necrosis factor-alpha; AUC, area under the curvealpha5; Nicotinic a

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Molecular mechanism of HIV-1 resistance to 3′-azido-2′,3′-dideoxyguanosine

Keywords: WT، نوع وحشی; RT, reverse transcriptase; RNase H, ribonuclease H; WT, wild-type; NRTI, nucleoside RT inhibitor; TP, triphosphate; DP, diphosphate; MP, monophosphate; T/P, template/primer; NRTIs, nucleoside reverse transcriptase inhibitors; 3′-Azido-ddG, 3′-azido-2′,3′-

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Genetic or pharmacologic disruption of the calcineurin-nuclear factor of activated T-cells axis prevents social stress-induced voiding dysfunction in a murine model

Keywords: WT، نوع وحشی; Social stress; Voiding dysfunction; Barrington's nucleus; Nuclear factor of activated T-cells; Corticotropin releasing factorNFAT, nuclear factor of activated T cells; CsA, cyclosporine; KO, knockout; WT, wild-type; BN, Barrington's nucleus; CRF, corticot

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Cannabinoid control of brain bioenergetics: Exploring the subcellular localization of the CB1 receptor

Keywords: WT، نوع وحشی; Brain bioenergetics; CB1 receptor; mitochondria; electron microscopy; antibodies; organelle purificationCB1, cannabinoid type 1 receptor; BSA, bovine serum albumin; DAB–Ni, Ni-intensified 3,3ʹ-diaminobenzidine–4HCl; DMSO, dimethyl sulfoxide; WT, wild-type

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Essential role of IL-10/STAT3 in chronic stress-induced immune suppression

Keywords: WT، نوع وحشی; TLR4, toll-like receptor 4; WT, wild-type; KO, knockout; DC, dendritic cell; IHC, immunohistochemistry; Th1, T helper-1; Th2, T helper-2TLR4; STAT3; p38; Chronic stress; Apoptosis; Immune suppression

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

S100A4 regulates the Src-tyrosine kinase dependent differentiation of Th17 cells in rheumatoid arthritis

Keywords: WT، نوع وحشی; mBSA, methylated bovine serum albumin; WT, wild-type; KO, knock-out; IFNγ, interferon-gamma; IL, interleukin; RORγt, retinoic acid orphan receptor gamma t; RA, rheumatoid arthritis; TNF, tissue necrosis factor; TCR, T-cell receptor; Th, helper T cell; STA

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

The Assembly Pathway of an Icosahedral Single-Stranded RNA Virus Depends on the Strength of Inter-Subunit Attractions

Keywords: WT، نوع وحشی; CCMV, cowpea chlorotic mottle virus; ssRNA, single-stranded RNA; BMV, brome mosaic virus; VLP, virus-like particle; CP, capsid protein; wt, wild-type; EM, electron microscopy; cryo-EM, cryo-electron microscopy; ARM, arginine-rich motif; DOL, density of la

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Functional role of alpha7 nicotinic receptor in chronic neuropathic and inflammatory pain: Studies in transgenic mice

Keywords: WT، نوع وحشی; nAChR(s), nicotinic acetylcholine receptor(s); i.p., intraperitoneal; KO, knock-out; KI, knock-in; WT, wild-type; CFA, complete Freund's adjuvantChronic pain; Alpha7 nicotinic receptors; Inflammation; Nicotine; Mice

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Longitudinal assessment of endothelial function in the microvasculature of mice in-vivo

Keywords: WT، نوع وحشی; ACh, Acetylcholine; CVD, Cardiovascular disease; LDI, Laser Doppler imaging; L-NAME, N (G)-nitro-l-arginine methyl ester hydrochloride; NO, Nitric oxide; PE, Phenylephrine; SNP, Sodium nitroprusside; WT, Wild-type

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Albumin domain II mutant with high bilirubin binding affinity has a great potential as serum bilirubin excretion enhancer for hyperbilirubinemia treatment

Keywords: WT، نوع وحشی; BR, 4Z,15Z-bilirubin-IXα; HSA, human serum albumin; BDL, bile duct ligation; SPR, surface plasmon resonance; WT, wild-type; HRP, horseradish peroxidaseHuman serum albumin; Bilirubin; Liver failure; Hyperbilirubinemia; Phage display

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Experimental nonalcoholic fatty liver disease in mice leads to cytochrome p450 2a5 upregulation through nuclear factor erythroid 2-like 2 translocation

Keywords: WT، نوع وحشی; ARE, Antioxidant response element; Nrf2, Nuclear factor erythroid 2-like 2; KO, Knockout; WT, Wild-type; P450, Cytochrome P450; NASH, Nonalcoholic steatohepatitis; NAFLD, Nonalcoholic fatty liver disease; co-IP, Co-immunoprecipitationCoumarin 7-hydroxylas

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Dual Effects of IL-1 Overactivity on the Immune System in a Mouse Model of Arthritis due to Deficiency of IL-1 Receptor Antagonist

Keywords: WT، نوع وحشی; Arthritis; Gene expression; Mouse; TranscriptomeRA, rheumatoid arthritis; IL-1, interleukin 1; IL-1rn, IL-1 receptor antagonist; Pira, paired-Ig-like receptor A; BFA, brefeldin A; WT, wild-type; KO, IL-1rn knockout; 1M, 1 month; 4M, 4 months; Hsp, heat sh

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Deletion of circadian gene Per1 alleviates acute ethanol-induced hepatotoxicity in mice

Keywords: WT، نوع وحشی; Per1, Period; TG, triglyceride; WT, wild-type; PPAR, peroxisome proliferators activated receptor; ALD, alcohol liver disease; CYP2E1, cytochrome P450-2E1; GSH, glutathione; SOD, superoxide dismutase; SREBP-1c, sterol regulatory element binding protein-1c;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Transgenic mice with high endogenous omega-3 fatty acids are protected from spinal cord injury

Keywords: WT، نوع وحشی; PUFAs, polyunsaturated fatty acids; CNS, central nervous system; SCI, spinal cord injury; TBI, traumatic brain injury; WT, wild-type; DRG, dorsal root ganglion; AA, arachidonic acid; BMS, Basso Mouse Scale; CO2, carbon dioxide; MSD, Meso Scale Discovery;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Membrane-bound α-synuclein interacts with glucocerebrosidase and inhibits enzyme activity

Keywords: WT، نوع وحشی; α-syn, α-synuclein; PD, Parkinson disease; LBs, Lewy bodies; GD, Gaucher disease; GCase, glucocerebrosidase; WT, wild-type; α-glu A, acid α-glucosidase; N15, α-syn peptide residues 1–15; C23, α-syn peptide residues 118–140; MES, 2-(N-morpholino)ethanesulf

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Effects of endoplasmic reticulum stressors on maturation and signaling of hemizygous and heterozygous wild-type and mutant forms of KIT

Keywords: WT، نوع وحشی; KIT receptor; Cell line; Imatinib; Glycosylation; Protein trafficking; AKTER, endoplasmic reticulum; IM, imatinib mesylate; RTK, receptor tyrosine kinase; WT, wild-type

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Generating conformation-specific synthetic antibodies to trap proteins in selected functional states

Keywords: WT، نوع وحشی; sAB, synthetic antibody; CDR, complementarity determining region; ELISA, enzyme linked immunosorbent assay; PTM, post translational modification; WT, wild-type; CMC, critical micelle concentration; ChIP, chromatin immunoprecipitationSynthetic antibody; Ph

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Cell-cycle and DNA damage regulation of the DNA mismatch repair protein Msh2 occurs at the transcriptional and post-transcriptional level

Keywords: WT، نوع وحشی; uORF, upstream open reading frame; MMS, methyl methane sulfonate; HU, hydroxyurea; αF, alpha factor; WT, wild-type; CAN, canavanine; 5-FOA, 5-fluoro-orotic acid; MCB, MluI cell cycle box; SCB, Swi6/4 cell cycle box; CCB, cell-cycle boxMismatch repair; Cel

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه