Keywords: Atherosclerosis; T2DM; NGAL; YKL-40; FABP-4;
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Keywords: Inflammation; Bipolar disorder; Mania; Depression; Biomarkers; ADHD; Attention Deficit Hyperactivity Disorder; ANCOVA; Analysis of Covariance; AITD; Autoimmune Thyroid Disease; α1-AT; α1-Antitrypsin; α1S; α1 Acid glycoprotein; BA; Broadmann's Area; BA
Keywords: Helicobacter pylori; Atherosclerosis; YKL-40; Inflammation; Vascular dementia
Keywords: Status epilepticus; Pilocarpine; Hippocampus; YKL-40; Neuronal injury; Inflammation
Chitinase 3 like 1 (CHI3L1) promotes vasculogenic mimicry formation in cervical cancer
Keywords: YKL-40; vasculogenic mimicry; angiogenesis; dual staining;
Relationship between cortical thickness and cerebrospinal fluid YKL-40 in predementia stages of Alzheimer's disease
Keywords: Cortical thickness; YKL-40; Neuroinflammation; Preclinical Alzheimer's disease; CSF biomarkers; Structural MRI;
Alzheimer's disease biomarker-guided diagnostic workflow using the added value of six combined cerebrospinal fluid candidates: Aβ1-42, total-tau, phosphorylated-tau, NFL, neurogranin, and YKL-40
Keywords: Alzheimer's disease; Alzheimer's disease dementia; Diagnostic biomarkers; Biomarker combination; Cerebrospinal fluid; Neurofilament light chain; Neurogranin; YKL-40; Pathophysiological pathways; Neurodegeneration; Clinical diagnosis; Cognitive aging; Mild
Mortality prediction in stable hemodialysis patients is refined by YKL-40, a 40-kDa glycoprotein associated with inflammation
Keywords: cardiovascular; chronic inflammation; hemodialysis; mortality; risk; YKL-40;
YKL-40 levels increase with declining ankle-brachial index and are associated with long-term cardiovascular mortality in peripheral arterial disease patients
Keywords: YKL-40; CHI3L1; Cardiovascular mortality; Peripheral arterial disease; Atherosclerosis;
YKL-40: A biomarker for early nephropathy in type 2 diabetic patients and its association with inflammatory cytokines
Keywords: Diabetic Nephropathy; YKL-40; Cytokines; Type-2-diabetes; Inflammation;
Differential regulation of the pro-inflammatory biomarker, YKL-40/CHI3L1, by PTEN/Phosphoinositide 3-kinase and JAK2/STAT3 pathways in glioblastoma
Keywords: YKL-40; PTEN; PI3K; JAK2/STAT3; Transcriptomes;
Genetic and epigenetic regulation of YKL-40 in childhood
Keywords: YKL-40; CHI3L1; asthma; epigenetics; DNA methylation; genetics; adjOR; Adjusted odds ratio; BAMSE; Swedish Barn/Children, Allergy, Milieu, Stockholm, Epidemiological survey; CHI3L1; Chitinase 3-like 1; GWAS; Genome-wide association study; INMA; Spanish
YKL-40 is a novel biomarker for predicting hypertension incidence among prehypertensive subjects: A population-based nested case-control study in China
Keywords: YKL-40; Prehypertension; Hypertension; Nested case-control study;
Featured ArticleTwo-level diagnostic classification using cerebrospinal fluid YKL-40 in Alzheimer's disease
Keywords: Alzheimer's disease; Biomarkers; Biomarker-based diagnosis; Cerebrospinal fluid; Clinical diagnosis; Dementia; Diagnostic biomarkers; Frontotemporal dementia; Mild cognitive impairment; Neurodegeneration; Neuroinflammation; YKL-40;
HIV/neuroAIDS biomarkers
Keywords: Aβ42-β; amyloid of 42 kiloDaltons; AD; Alzheimer's disease; APP; amyloid precursor protein; ALS; amyotrophic lateral sclerosis; BOLD; blood oxygen level-dependent contrast imaging; cART; combination anti-retroviral therapy; CBF; cerebral blood flow; C
Short CommunicationYKL-40 as marker of severe lung disease in cystic fibrosis patients
Keywords: YKL-40; Cystic fibrosis; Pulmonary pseudomonas infection; Acute pulmonary exacerbation; Lung function decline;
Effect of serum YKL-40 on coronary collateral development and SYNTAX score in stable coronary artery disease
Keywords: YKL-40; Inflammation; Angiogenesis; Collateral development; SYNTAX score;
Levels of the inflammation marker YKL-40 in young adults exposed to intrauterine hyperglycemia
Keywords: BMI; body mass index; BP; background population; CV; coefficient of variation; GDM; gestational diabetes mellitus; 2-h; 2Â hour; LGA; large for gestational age; MS; metabolic syndrome; NoGDM; not GDM; O; offspring; OGTT; oral glucose tolerance test; SGA;
Study of serum YKL-40 in children with bronchial asthma
Keywords: Asthma; YKL-40; Biomarker; (Chitinase-3-like-1); Severity
YKL-40 is a CSF biomarker of intrathecal inflammation in secondary progressive multiple sclerosis
Keywords: Multiple sclerosis; SF; Biomarker; YKL-40; GFAp; sCD14; MRI;
Diagnostic potential of YKL-40 in bladder cancer
Keywords: Bladder cancer; YKL-40; Bladder tumor antigen;
Diagnostic and prognostic values of preoperative serum levels of YKL-40, HE-4 and DKK-3 in endometrial cancer
Keywords: Endometrial cancer; HE-4; YKL-40; DKK-3; Tumor markers; Prognostic factors
Chitinase-3-like protein-1 (YKL-40) as a marker of endothelial dysfunction in obstructive sleep apnea
Keywords: Obstructive sleep apnea; YKL-40; Chitinase-3-like protein-1; Endothelial dysfunction; Hypertension;
Serum YKL-40 in young patients with β-thalassemia major: Relation to hepatitis C virus infection, liver stiffness by transient elastography and cardiovascular complications
Keywords: β-thalassemia; YKL-40; Liver fibrosis; Transient elastography; Hepatitis C; Cardiac disease; Iron overload;
Chitinase 3-like 1 expression by human (MG63) osteoblasts in response to lysophosphatidic acid and 1,25-dihydroxyvitamin D3
Keywords: Osteoblasts; Active vitamin D; Lysophosphatidic acid; Differentiation; Alkaline phosphatase; YKL-40;
Cerebrospinal fluid ratios with Aβ42 predict preclinical brain β-amyloid accumulation
Keywords: Amyloid; PiB; PET; Cerebrospinal fluid; Biomarkers; Preclinical AD; Alzheimer's disease; Biological parametric mapping; Aβ42; Tau; NFL; MCP-1; YKL-40; Linear mixed-effects
Evaluation of pleural fluid YKL-40 as a marker of malignant pleural effusion
Keywords: YKL-40; Pleural effusion; Malignant pleural effusion
Plasma YKL-40 during pregnancy and gestational diabetes mellitus
Keywords: YKL-40; IL-6; Gestational diabetes mellitus;
Serum YKL-40 levels as a prognostic factor in patients with intracerebral hemorrhage
Keywords: Intracerebral hemorrhage; Inflammation; Prognosis; YKL-40
Protective role of bortezomib in steatotic liver ischemia/reperfusion injury through abrogation of MMP activation and YKL-40 expression
Keywords: Bortezomib; Matrix metalloproteinases; YKL-40; Liver transplantation; I/R injury
Circulating YKL-40 in patients with essential thrombocythemia and polycythemia vera treated with the novel histone deacetylase inhibitor vorinostat
Keywords: Ykl-40; Essential thrombocythemia; Polycythemia vera; Vorinostat; Phase II study;
Prognostic effect of serum and tissue YKL-40 levels in bladder cancer
Keywords: Bladder cancer; YKL-40; Prognosis; Inflammation; Serum; Urine;
Partially acetylated chitooligosaccharides bind to YKL-40 and stimulate growth of human osteoarthritic chondrocytes
Keywords: Cell culture; Chitolectin; Chitooligosaccharides; Chondrocytes; High affinity binding; Rheumatoid arthritis; YKL-40;
Serum YKL-40 predicts long-term mortality in patients with stable coronary disease: A prognostic study within the CLARICOR trial
Keywords: AP; angina pectoris; CABG; coronary bypass surgery; CAD; coronary artery disease; ECG; electrocardiography; HF; heart failure; hs-CRP; high-sensitivity C-reactive protein; LVEF; left ventricular ejection fraction; MI; myocardial infarction; NT-proBNP; N-t
The chitinase-like protein YKL-40 increases mucin5AC production in human bronchial epithelial cells
Keywords: Mucin5AC; YKL-40; Protease-activating receptor 2; Extracellular signal-regulated kinase; Nuclear factor κB; Focal adhesion kinase;
The relation of circulating YKL-40 to levels and decline of lung function in adult life
Keywords: YKL-40; Lung function; Smoking;
Serum Biomarkers and Transient Elastography as Predictors of Advanced Liver Fibrosis in a United States Cohort: The Boston Children's Hospital Experience
Keywords: ALT; Alanine aminotransferase; APRI; Aspartate aminotransferase:platelet ratio index; AST; Aspartate aminotransferase; AUC; Area under the receiver operating characteristic curve; GGTP; Gamma-glutamyl transpeptidase; HA; Hyaluronic acid; NAFLD; Nonalcohol
Clinical implication of plasma and urine YKL-40, as a proinflammatory biomarker, on early stage of nephropathy in type 2 diabetic patients
Keywords: Type 2 diabetes mellitus; Diabetic nephropathy; YKL-40; Albuminuria; Inflammation
A promoter variant in the chitinase 3-like 1 gene is associated with serum YKL-40 level and personality trait
Keywords: Schizophrenia; Chitinase-3-like 1 (CHI3L1) gene; YKL-40; Temperament and character inventory (TCI); Self-transcendence
Comparative study of YKL-40, S-100B and LDH as monitoring tools for Stage IV melanoma
Keywords: Metastatic melanoma; Prognosis; Serum marker; S100B; LDH; YKL-40;
Pre-analytical effects of blood sampling and handling in quantitative immunoassays for rheumatoid arthritis
Keywords: ACR; American College of Rheumatology; BD; Becton Dickinson; cAPOE; citrullinated apolipoprotein; cBig; citrullinated biglycan; cClu; citrullinated clusterin; CCP; cyclic citrullinated peptides cFibA1 and cFibA2, citrullinated fibrinogen; cH2B; citrullina
Study of biomaterial-induced macrophage activation, cell-mediated immune response and molecular oxidative damage in patients with dermal bioimplants
Keywords: AOPPs; advanced oxidation protein products; AR; adverse reactions; CAHA; calcium hydroxylapatite; ChT; human chitotriosidase; FACS; fluorescence-activated cell sorting; FLPs; fluorescent peroxidation products; HA; hyaluronic acid; HLA-class II; human leuk
IL-6, but not TNF-α, increases plasma YKL-40 in human subjects
Keywords: Cytokines; YKL-40; IL-6; TNF-α
Increased tissue immunoexpression of YKL-40 protein in high grade serous ovarian cancers
Keywords: YKL-40; Ki-67; Proliferation; Ovarian serous tumors
Plasma YKL-40 levels in healthy subjects from the general population
Keywords: Biomarkers; CHI3L1; Reference levels; YKL-40
Genetic polymorphisms in chitinase 3-like 1 (CHI3L1) are associated with circulating YKL-40 levels, but not with angiographic coronary artery disease in a Chinese population
Keywords: Polymorphism; Coronary artery disease; Inflammation; YKL-40;
Serum and BALF YKL-40 levels are predictors of survival in idiopathic pulmonary fibrosis
Keywords: YKL-40; Chitinase-like proteins; Interstitial lung disease; CHI3L1; Single nucleotide polymorphism
The Prognostic Value of YKL-40 Concentrations in Nonmyeloablative Conditioning Allogeneic Hematopoietic Cell Transplantation
Keywords: YKL-40; Ch13L1; Hematopoietic cell transplantation; Nonmyeloblative conditioning; Graft-versus-host disease; Prognosis
Increased serum YKL-40 and C-reactive protein levels are associated with angiographic lesion progression in patients with coronary artery disease
Keywords: YKL-40; C-reactive protein; Coronary artery disease; Angiography;
The chitinase 3-like 1 gene and schizophrenia: Evidence from a multi-center case–control study and meta-analysis
Keywords: Schizophrenia; Chitinase-3-like-1 (CHI3L1) gene; YKL-40; Single nucleotide polymorphism (SNP); Association study; Meta-analysis