دانلود مقالات ISI درباره Zbg + ترجمه فارسی

اثرات ضد سرطان از ترکیبات به طور طبیعی مشتق شده با هدف هیستون دیازتیلاز 6 مرتبط است

Anti-cancer effects of naturally derived compounds targeting histone deacetylase 6-related pathways

Keywords: FK228 (PubChem CID: 5352062); PXD101 (PubChem CID: 6918638); SAHA (PubChem CID: 5311); LBH-589 (PubChem CID: 6918837); tubacin (PubChem CID: 6675804); tubastatin A (PubChem CID: 49850262); ACY-1215 (PubChem CID: 53340666); ACY-241 (PubChem CID: 53340426);

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2018 سفارش ترجمه

کنگوات های بیفکنیک با فعالیت مهار کننده قوی نسبت به سیکلوکوکسیژناز و هیستون دیازتیلاز

Bifunctional conjugates with potent inhibitory activity towards cyclooxygenase and histone deacetylase

Keywords: HDAC; histone deacetylase; HDACi; histone deacetylase inhibitors; COX; cyclooxygenases; NSAIDs; non-steroidal anti-inflammatory drugs; AR; androgen receptor; ZBG; zinc binding group; PGE2; prostaglandin E2;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2017 سفارش ترجمه

Design, synthesis and evaluation of antiproliferative activity of melanoma-targeted histone deacetylase inhibitors

Keywords: HDAC; histone deacetylase; HDACi; histone deacetylase inhibitors; ZBG; zinc binding group;

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2017 سفارش ترجمه

طراحی، سنتز و ارزیابی بیولوژیکی بنزامید های جدید کومارین مبتنی بر مهار کننده های هیستون دیازتیلاز و داروهای ضد سرطان

Design, synthesis and biological evaluation of novel coumarin-based benzamides as potent histone deacetylase inhibitors and anticancer agents

Keywords: Histone deacetylase inhibitors; Coumarin; 2-AminoBenzamide; Docking; Molecular dynamics; HDAC; Histone Deacetylases; HATs; Histone Acetyl Transferases; HSP 90; Heat Shock Protein 90; SAHA; suberoylanilide hydroxamic acid; TSA; Trichostatin A; ZBG; Zinc Bi

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2017 سفارش ترجمه

Design, synthesis and biological screening of 2-aminobenzamides as selective HDAC3 inhibitors with promising anticancer effects

Keywords: B16F10; murine melanoma cells; CDCl3; deuterated chloroform; CTCL; cutaneous T-cell lymphoma; DCM; dichloromethane; DFT; density functional theory; DMAP; 4-Dimethylaminopyridine; DMEM; Dulbecco's modified Eagle's media; DMF; dimethylformamide; DMSO; dimet

دانلود رایگان متن کامل مقاله ISI 53 صفحه سال انتشار : 2018 سفارش ترجمه

Structural insights of SmKDAC8 inhibitors: Targeting Schistosoma epigenetics through a combined structure-based 3D QSAR, in vitro and synthesis strategy

Keywords: 3D QSAR; Three-Dimensional Quantitative Structure-Activity Relationships; BZDs; Benzodiazepine Derivatives; hKDAC; Human Lysine Deacetylase; KDACI; Lysine Deacetylase Inhibitor; NCI; National Cancer Institute; NEt3; Triethylamine; SLAs; Simplified Largazo

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2017 سفارش ترجمه

Potent dual inhibitors of Plasmodium falciparum M1 and M17 aminopeptidases through optimization of S1 pocket interactions

Keywords: Plasmodium falciparum; Malaria; Aminopeptidase inhibitors; Hydroxamic acid; Zinc-binding group; MAP; metalloaminopeptidase; ZBG; zinc binding group; Pf; Plasmodium falciparum; Dd2 SpiroR; NITD609-RDd2 clone#2; CDI; carbonyldiimidazole; FCC; flash column c

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2016 سفارش ترجمه

Design, synthesis and biological evaluation of bisthiazole-based trifluoromethyl ketone derivatives as potent HDAC inhibitors with improved cellular efficacy

Keywords: Bisthiazole; Histone deacetylases; ZBG; Trifluoromethyl ketones;

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2016 سفارش ترجمه

A dual inhibitor of matrix metalloproteinases and a disintegrin and metalloproteinases, [18F]FB-ML5, as a molecular probe for non-invasive MMP/ADAM-targeted imaging

Keywords: ACN; acetonitrile; AcOH; acetic acid; ADAM; a disintegrin and metalloproteinase; CD; catalytic domain; DCC; N,N′-dicyclohexylcarbodiimide; DCM; dichloromethane; DMF; N,N-dimethylformamide; ECM; extracellular matrix; EOB; end of bombardment; EOS; end of

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Saccharin: A lead compound for structure-based drug design of carbonic anhydrase IX inhibitors

Keywords: CA; carbonic anhydrase; Ki; inhibition constant; ZBG; zinc binding group; Saccharin; Metalloenzyme; Carbonic anhydrase IX; CA IX-mimic; Structure-based drug design;

دانلود رایگان متن کامل مقاله ISI 24 صفحه سال انتشار : 2015 سفارش ترجمه

Design, synthesis and biological evaluation of 5-hydroxy, 5-substituted-pyrimidine-2,4,6-triones as potent inhibitors of gelatinases MMP-2 and MMP-9

Keywords: MMP; Gelatinases; ZBG; QSAR; Molecular docking

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

New hydroxypyrimidinone-containing sulfonamides as carbonic anhydrase inhibitors also acting as MMP inhibitors

Keywords: BSA; benzenesulfonamide; HPM; hydroxypyrimidinone; CA; carbonic anhydrase; MMP; matrix metalloproteinase; ZBG; zinc-binding group; HA; hydroxamic acid; Hydroxypyrimidinones; Carbonic anhydrase inhibitors; Sulfonamides; MMP inhibitors;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه