دانلود مقالات ISI درباره Β-Trcp + ترجمه فارسی

عناصر پاسخ آنتی اکسیدان: کشف، کلاس ها، تنظیمات و برنامه های کاربردی بالقوه

Antioxidant response elements: Discovery, classes, regulation and potential applications

Keywords: 3-MC; 3-methylcholanthrene; Ah; aryl hydrocarbon; AhE; aryl hydrocarbon receptor; AP-1; activator protein-1; ARE; antioxidant response element; ATF4; activating transcription factor 4; β-NF; β-naphthoflavone; β-NF-RE; β-NF-responsive element; β-TRCP;

دانلود رایگان متن کامل مقاله ISI 61 صفحه سال انتشار : 2018 سفارش ترجمه

A partnership with the proteasome; the destructive nature of GSK3

Keywords: AMPK; AMP-activated protein kinase; ARE; antioxidant response element; β-TrCP; beta-transducin repeat containing protein; CKI; casein kinase-1; CHD; chromatin helicase DNA-binding factor; CRY; cryptochrome; EMT; epithelial-mesenchymal transition; FGD; fa

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

Mkp-1 protects mice against toxin-induced liver damage by promoting the Nrf2 cytoprotective response

Keywords: ALT; alanine aminotransferase; ARE; antioxidant response element; AST; aspartate transaminase; BHA; butylated hydroxyanisole; CCl4; carbon tetrachloride; β-TrCP; β-transducin repeat-containing protein; DMSO; dimethyl sulfoxide; GAPDH; glyceraldehyde-3-p

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2018 سفارش ترجمه

ERK1/2 activated PHLPP1 induces skeletal muscle ER stress through the inhibition of a novel substrate AMPK

Keywords: 2-NBDG; 2-(N-[7-nitrobenz-2-oxa-1,3-diazol-4-yl]amino)-2-deoxyglucose; AICAR; 5-aminoimidazole-4-carboxamide-1-b-d-ribofuranoside; AMPK; AMP-activated protein kinase; AS160; Akt Substrate of 160 kDa; ATF4; Activating Transcription Factor 4; AUC; area un

دانلود رایگان متن کامل مقاله ISI 64 صفحه سال انتشار : 2018 سفارش ترجمه

Deubiquitinase USP33 is negatively regulated by β-TrCP through ubiquitin-dependent proteolysis

Keywords: Protein ubiquitination; E3 ligase; β-TrCP; USP33;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

Modulation of proteostasis by transcription factor NRF2 and impact in neurodegenerative diseases

Keywords: α-SYN; alpha synuclein; β-TrCP; β-transducin repeat containing E3 ubiquitin protein ligase; Aβ; amyloid beta; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; AMPK; AMP-activated protein kinase; ARE; antioxidant response element; ASK1; apo

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Complexity of the Wnt/β‑catenin pathway: Searching for an activation model

Keywords: APC; adenomatous polyposis coli; BCL-9; B-cell lymphoma 9; BMPs; bone morphogenetic proteins; CARM; coactivator-associated arginine methyltransferase; CBP; CREB-binding protein; CK1α; casein kinase 1α; CRD; Cysteine-Rich Domain; DIX; Dishevelled interac

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2017 سفارش ترجمه

WNT inhibitory factor 1 promoter hypermethylation is an early event during gallbladder cancer tumorigenesis that predicts poor survival

Keywords: GBC; gallbladder cancer; WIF-1; WNT inhibitory factor 1; APC; adenomatous polyposis coli; CK1; casein kinase 1; GSK3; glycogen synthase kinase 3; β-Trcp; β-tranducin repeat-containing protein; TCF/LEF; T-cell factor family/lymphocyte enhancer factor; AF

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2017 سفارش ترجمه

BH3-only protein BIM: An emerging target in chemotherapy

Keywords: A1; Bcl-2-related protein A1; Apaf-1; Apoptotic protease-activating factor 1; ASK1; Apoptosis Signal Regulated Kinase 1; Bad; Bcl-2 associated agonist of cell death; Bak; Bcl-2 homologous antagonist/killer; Bax; Bcl-2-associated X protein; Bcl-2; B-cell l

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2017 سفارش ترجمه

Redox signaling in the gastrointestinal tract

Keywords: HNE; 4-hydroxynonenal; 8-OHdG; 8-oxo-7,8-dihydro-2′-deoxyguanosine; AP-1; Activator protein 1; APC; Adenomatous polyposis coli; APE-1; Apurinic/apyrimidinic endonuclease 1; Math1; Atonal homolog 1; Bax; BCL2-associated X protein; β-TrCP; Beta-transduci

دانلود رایگان متن کامل مقاله ISI 150 صفحه سال انتشار : 2017 سفارش ترجمه

Cullin 5-RING E3 ubiquitin ligases, new therapeutic targets?

Keywords: E3 ubiquitin ligase; Cullin RING ligase; Ubiquitin-proteasome system; Therapeutic targets; ASB; ankyrin repeat-containing proteins with a SOCS box; β-Trcp; β-transducin repeat-containing protein; BTB; bric-a-brac; CIS1; cytokine-inducible Src homology

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

The emerging roles of F-box proteins in pancreatic tumorigenesis

Keywords: Pancreatic cancer; F-box proteins; β-TrCP; Fbxw7; Fbxw8;

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2016 سفارش ترجمه

Regulation of the CNC-bZIP transcription factor Nrf2 by Keap1 and the axis between GSK-3 and β-TrCP

Keywords: Nrf2; Keap1; GSK-3; PKB/Akt; PI3K; PTEN; β-TrCP; ARE; antioxidant response element; tBHQ; tert-butyl hydroquinone; bZIP; basic-region leucine zipper; CDDO-Im; 1[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole; CNC; cap'n'collar; Cul1; cullin-1; Cu

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2016 سفارش ترجمه

Withaferin A induces Nrf2-dependent protection against liver injury: Role of Keap1-independent mechanisms

Keywords: Akt PKB; protein kinase B; APAP; acetaminophen; ALT; alanine aminotransferase; ARE; antioxidant response element; β-Trcp; beta-transducin repeat containing protein; CDDO-Im; 1[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole; Cul3; cullin-3; DMSO;

دانلود رایگان متن کامل مقاله ISI 37 صفحه سال انتشار : 2016 سفارش ترجمه

Skp1: Implications in cancer and SCF-oriented anti-cancer drug discovery

Keywords: Arf6; ADP-ribosylation factor 6; BIMEL; extra-long isoform of BIM; β-TRCP; β-transducin repeat-containing protein; CDCA3; cell division cycle associated 3; CDK; cyclin-dependent kinase; CENP-E; centrosome-associated protein E; Cks1; cyclin-dependent pro

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2016 سفارش ترجمه

An overview of chemical inhibitors of the Nrf2-ARE signaling pathway and their potential applications in cancer therapy

Keywords: AA; Ascorbic acid; AEM1; ARE expression modulator 1; AEG1; Astrocyte elevated gene-1; Akt; Protein kinase B; AMPK; AMP-activated protein kinase; APL; Acute promyelocytic leukemia; ARE; Antioxidant response element; ATO; Arsenic trioxide; Bach; BTB and CNC

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2016 سفارش ترجمه

Heme oxygenase-1-derived bilirubin counteracts HIV protease inhibitor-mediated endothelial cell dysfunction

Keywords: PI; protease inhibitors; ROS; reactive oxygen species; HO-1; heme oxygenase-1; CO; carbon monoxide; CORM2; carbon monoxide releasing molecule-2; iCORM2; inactivated carbon monoxide releasing molecule-2; CM-H2DCFDA; 5-(and-6)-chloromethyl-2,7-dichlorodihyd

دانلود رایگان متن کامل مقاله ISI 56 صفحه سال انتشار : 2016 سفارش ترجمه

Effect of TP53 16-bp and β-TrCP 9-bp INS/DEL polymorphisms in relation to risk of breast cancer

Keywords: BC; breast cancer; Β-TrCP; β-transducing repeat containing protein; CRC; colorectal cancer; CI; confidence interval; F; forward; HER2; human epidermal growth factor receptor 2; INS; insertion; OR; odds ratio; PCR; polymerase chain reaction; R; reverse;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Functional roles of HIV-1 Vpu and CD74: Details and implications of the Vpu-CD74 interaction

Keywords: AGTR1; angiotensin II type 1 receptor; β-TrCP; β-transducin repeat-containing protein; CD74-ICD; CD74 intracellular domain; CLIP; class-II-associated Ii-chain peptide; ER; endoplasmic reticulum; ERK-1/2; p44/p42 extracellular-signal-regulated kinase fam

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Silencing the alarms: Innate immune antagonism by rotavirus NSP1 and VP3

Keywords: Rotavirus; Innate immunity; Interferon signaling pathway; OAS/RNase L pathway; β-TrCP; NF-κB; Viral E3 ubiquitin ligase; Viral phosphodiesterase;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

The Nuclear Factor κB pathway: A link to the immune system in the radiation response

Keywords: Nuclear Factor κB; Immune system; Cellular radiation response; Linear energy transfer; Bystander effect; Chemokines; A20 (TNFAIP3); tumor necrosis factor inducible protein 3; ARD; ankyrin repeat domain; ATM; ataxia telangiectasia mutated protein; β-TrCP

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2015 سفارش ترجمه

Functional polymorphisms in Nrf2: implications for human disease

Keywords: AAO; age at onset; ALI; acute lung injury; AMD; age-related macular degeneration; ARE; antioxidant response element; BPD; bronchopulmonary dysplasia; β-TrCP; β-transducin repeats-containing proteins; CCA; cholangiocarcinoma; Cns; non-synonymous coding;

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2015 سفارش ترجمه

Mechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative disease

Keywords: Nrf2; Keap1; β-TrCP; GSK-3; Reactive oxygen species; Inflammation; Nutrient supply; Lipid metabolism; Glutathione; Thioredoxin; Free radicals; aldo-keto reductase (AKR);

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2015 سفارش ترجمه

Structural and functional characterization of Nrf2 degradation by glycogen synthase kinase 3/β-TrCP

Keywords: Nrf2; GSK-3; β-TrCP; Cell signaling; Oxidative stress;

دانلود رایگان متن کامل مقاله ISI 52 صفحه سال انتشار : 2015 سفارش ترجمه

The VTLISFG motif in the BH1 domain plays a significant role in regulating the degradation of Mcl-1

Keywords: Apoptosis; Mcl-1; Degradation motif; PEST domain; β-TrCP; β-transducin repeat-containing protein; Bax; Bcl-2-associated X protein; Bcl-2; B-cell lymphoma-2; BH domain; Bcl-2 homology domain; Bim; Bcl-2-interacting mediator; BSA; bovine serum albumin; Ca

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

TRIB2 inhibits Wnt/β-Catenin/TCF4 signaling through its associated ubiquitin E3 ligases, β-TrCP, COP1 and Smurf1, in liver cancer cells

Keywords: TRIB2; Tribbles homolog 2; CHX; cycloheximide; Smurf1; Smad ubiquitination regulatory factor 1; β-TrCP; beta-transducin repeat-containing E3 ubiquitin protein ligase; Ub; ubiquitin; IF; immunofluorescence; WB; Western blotting; Protein stability; Wnt/β-

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

A calpain-cleaved fragment of β-catenin promotes BCRABL1 + cell survival evoked by autophagy induction in response to imatinib

Keywords: ULK1; unc-51-like kinase; ATG; autophagy-related proteins; FIP200; focal adhesion interacting protein 200; PI3K; class III phosphoinositide 3-kinase; Vps; vacuolar protein sorting; LC3; microtubule-associated protein 1 light chain 3; PE; phosphatidylethan

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Wnt signaling in adult intestinal stem cells and cancer

Keywords: APC; Adenomatous Polyposis Coli; Axin; axis inhibition protein; β-TrCP; beta-transducin repeat containing protein; BMP; bone morphogenic protein; CBC; crypt base columnar; CRC; colorectal carcinoma; CSCs; cancer stem cells; Dkk; Dickkopf; FAP; Familial A

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Modulation of NRF2 signaling pathway by nuclear receptors: Implications for cancer

Keywords: AKR1C; aldo-keto reductases 1C1 and 1C2; ARE; antioxidant response element; ATRA; all-trans retinoic acid; Bach1; BTB and CNC homologue 1; BBN; (N-nitrosobutyl(4-hydroxybutyl)amine); Bcl-2; B-cell lymphoma 2; Bcl-xL; B-cell lymphoma-extra-large; β-TrCP

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Nrf2, the master redox switch: The Achilles' heel of ovarian cancer?

Keywords: ARE; antioxidant response element; ATF; artificial transcription factor; BER; base excision repair; β-TrCP; beta-transducin repeat-containing protein; CNL; copy number loss; dsDNA; double strand DNA; EOC; epithelial ovarian cancer; EEE; engineered epigen

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2014 سفارش ترجمه

Functional characterization of Anaphase Promoting Complex/Cyclosome (APC/C) E3 ubiquitin ligases in tumorigenesis

Keywords: APC/C; Anaphase Promoting Complex/Cyclosome; AOM; azoxymethane; Bub3; budding uninhibited by benzimidazole protein 3; BubR1; bub1-related protein; Cdc20; cell division cycle 20; Cdh1; Cdc20 homologue protein 1; DMBA; 7,12-dimethylbenz-α-anthracene; Emi1;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2014 سفارش ترجمه

Ubiquitin E3 ligase SCFβ-TRCP regulates TRIB2 stability in liver cancer cells

Keywords: TRIB2; tribbles homolog 2; HCC; hepatocellular carcinoma; IF; immunofluorescence; CHX; cycloheximide; β-TRCP; beta-transducin repeat containing E3 ubiquitin protein ligase; SCF complex; SKP1-cullin-F-box complex; TDD domain; TRIB2 degradation domain;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

SIRT1 suppresses cellular accumulation of β-TrCP E3 ligase via protein degradation

Keywords: β-TrCP; SIRT1; Post-translational degradation; Pyruvate; Resveratrol; Nucleus;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Tubulin polymerization promoting protein 1 (TPPP1) increases β-catenin expression through inhibition of HDAC6 activity in U2OS osteosarcoma cells

Keywords: CK1; caesin kinase 1; GSK3β; glycogen synthase kinase 3β; HDAC6; histone deacetylase 6; ROCK; rho-associated coiled-coil kinase; TPPP1; tubulin polymerization promoting protein 1; β-TrCP; β-transducin repeat-containing protein; β-Catenin; TPPP1; ROCK

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

The F-box protein β-TrCP promotes ubiquitination of TRF1 and regulates the ALT-associated PML bodies formation in U2OS cells

Keywords: TRF1; β-TrCP; Ubiquitination; PML;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

MicroRNA-106b-25 cluster targets β-TRCP2, increases the expression of Snail and enhances cell migration and invasion in H1299 (non small cell lung cancer) cells

Keywords: β-TRCP; β-transducin repeat-containing protein; NSCLC; non small cell lung cancer; TGF-β; transforming growth factor-β; EV; pmiRex-EV (empty vector) expressing H1299 cells; CL; pmiRex-CL (miR-106b-25 cluster) expressing H1299 cells; β-TRCP; miR-106b-

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Wnt/β-catenin signaling activates bone morphogenetic protein 2 expression in osteoblasts

Keywords: ALP; alkaline phosphatase; BGJ medium; Biggers, Gwatkin, and Judah medium; BMP; bone morphogenetic protein; β-TrCP; β-transducin repeat-containing protein; Col1a1; type I collagen 1a1; CTGF; connective-tissue growth factor; CREB; cAMP responsive element

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2013 سفارش ترجمه

Modulators of the hedgehog signaling pathway

Keywords: Antitumor agents; Cyclopamine; Hedgehog signaling; AKT; protein kinase B; ALP; alkaline phosphatase; BCC; basal cell carcinoma; BCR-ABL1; breakpoint cluster region-Abelson murine leukemia; β-TrCP; β-transducin repeat containing protein; BMP; bone morpho

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2010 سفارش ترجمه

Multiple isoforms of β-TrCP display differential activities in the regulation of Wnt signaling

Keywords: β-TrCP; Isoforms; Alternative splicing; β-catenin; Wnt; Ubiquitination;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Clinorotation prevents differentiation of rat myoblastic L6 cells in association with reduced NF-κB signaling

Keywords: DMEM; Dulbecco's modified Eagle's medium; IKK; IκB kinase; MHC; myosin heavy chain; JAXA; Japan Aerospace Exploration Agency; PAGE; polyacrylamide gel electrophoresis; PBS; phosphate-buffered saline; RT-PCR; reverse transcription-polymerase chain reactio

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه

Solution structure of a peptide derived from the oncogenic protein β-Catenin in its phosphorylated and nonphosphorylated states

Keywords: β-Catenin; β-TrCP; Molecular modeling; NMR spectroscopy; Phosphorylated peptide structure; Wingless/Wnt signals;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2005 سفارش ترجمه