کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10027759 | 1591914 | 2005 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Antibiotic resistance and class 1 integron patterns of non-typhoidal human Salmonella serotypes isolated in Hungary in 2002 and 2003
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
میکروبیولوژی و بیوتکنولوژی کاربردی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Antibiotic resistance and class 1 integron patterns of non-typhoidal human Salmonella serotypes isolated in Hungary in 2002 and 2003 Antibiotic resistance and class 1 integron patterns of non-typhoidal human Salmonella serotypes isolated in Hungary in 2002 and 2003](/preview/png/10027759.png)
چکیده انگلیسی
The antibiotic resistance profiles of 5178 Salmonella strains representing 19 non-typhoidal serotypes isolated from human salmonellosis cases in Hungary in 2002 and 2003 were analysed for resistance to 10 antibiotic agents. The most frequent resistances were to nalidixic acid (Nx), streptomycin (S), tetracycline (Tc), ampicillin (Amp) and chloramphenicol (Cm) (ranging from 27% to 13%). Forty-five percent of the Salmonella Typhimurium strains were multiple resistant and belonged mainly to the definitive phage types 104 and U302. A prevalence of 83-94% of strains of serotypes S. Infantis, S. Hadar and S. Virchow was observed with the NxSTc resistance pattern, sometimes complemented with other resistances. Multiple resistance was uncommon in S. Enteritidis; nevertheless, 20% of the strains, most of which belonged to phage type 4, were nalidixic acid resistant. One strain of S. Typhimurium was found to be resistant to ciprofloxacin. Four S. Typhimurium strains were resistant to cefotaxime and produced extended-spectrum β-lactamase. Selected isolates were screened for the presence of class 1 integrons by polymerase chain reaction (PCR). Nucleotide sequencing of the PCR products revealed nine different variable regions. One resistance gene was identified in five variable regions (aadA1, aadA2, aadA23, dfrV and pse-1), and four variable regions carried two resistance gene cassettes (aadB-catB3, dhfrI-aadA, dfrA17-aadA5 and oxa-1-aadA1).
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Antimicrobial Agents - Volume 26, Issue 2, August 2005, Pages 126-132
Journal: International Journal of Antimicrobial Agents - Volume 26, Issue 2, August 2005, Pages 126-132
نویسندگان
Noémi Nógrády, István Gadó, Ákos Tóth, Judit Pászti,