کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10064744 | 1599917 | 2005 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Apoptosis of HeLa cell lines incubated with retinol
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موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
زنان، زایمان و بهداشت زنان
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Apoptosis of HeLa cell lines incubated with retinol Apoptosis of HeLa cell lines incubated with retinol](/preview/png/10064744.png)
چکیده انگلیسی
The higher concentrations of soluble APO-1/Fas antigen in supernatants from the HeLa cell line without retinol may constitute a protective mechanism of the cells infected with the virus before undergoing Fas/FasL-dependent apoptosis. Lower concentrations of sAPO-1/Fas antigen in the supernatant from HeLa cell culture incubated with retinol may suggest that mechanisms protecting infected cells against Fas/FasL-mediated apoptosis become defective under the influence of retinol. Our studies confirm that Vitamin A and its analogues inhibit the proliferation of cells associated with HPV infection and suggest promising effects of retinoid therapy in inhibiting the progression of early cervical lesions to cancer.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Obstetrics & Gynecology and Reproductive Biology - Volume 119, Issue 1, 1 March 2005, Pages 119-122
Journal: European Journal of Obstetrics & Gynecology and Reproductive Biology - Volume 119, Issue 1, 1 March 2005, Pages 119-122
نویسندگان
U. Gasowska-Giszczak, D. Darmochwal-Kolarz, A. Kwasniewska, I. Dziubinska-Parol, J. Rolinski, J. Oleszczuk,