ORIGINAL RESEARCH-PHARMACOTHERAPY: Efficacy of Sildenafil Citrate in Men with Erectile Dysfunction Following Radical Prostatectomy: A Systematic Review of Clinical Data

The results of these studies demonstrate that with sildenafil, more than one third of patients with postprostatectomy ED achieved erection sufficient for intercourse. The odds of responding improved 12‐fold with preservation of at least one neurovascular bundle. Early treatment failure does not necessarily imply lack of efficacy in the future, and patients should be encouraged to continue trying sildenafil, titrating up to 100 mg as needed. Montorsi F, and McCullough A. Efficacy of sildenafil citrate in men with erectile dysfunction following radical prostatectomy: a systematic review of clinical data. J Sex Med 2005;2:658-667.