Late preconditioning with isoflurane in cultured rat cortical neurones

Isoflurane induced late preconditioning in cultured rat cortical neurones. Ischaemic and pharmacological preconditioning with diazoxide and isoflurane induced ischaemic tolerance in the cultured neurones via mitoKATP channels without an increase in Kir6.2 expression, and induced upregulation of EAAC1 expression.