Characterization and comparison of recombinant human and rat TRPV1 receptors: effects of exo- and endocannabinoidsâ€

There were small differences in the pharmacology of rat and human TRPV1 receptors. Whilst capsaicin activated TRPV1 and Δ9-tetrahydrocannabinol activated CB1, anandamide is an endogenous agonist for both receptor systems.