کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10130390 | 1645337 | 2018 | 30 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Camel whey protein hydrolysates displayed enhanced cholesteryl esterase and lipase inhibitory, anti-hypertensive and anti-haemolytic properties
ترجمه فارسی عنوان
هیدرولیز پروتئین آب پنیر شتر نشان داده است که افزایش کلسترول استراز و مهار کننده های لیپاز مهار کننده، ضد فشار خون بالا و ضد کلسترول
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
شتر گوشتی، هیدرولیزات، ضد فشار خون، ضد چاقی، تریپسین، پپسین،
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
دانش تغذیه
چکیده انگلیسی
Camel whey protein hydrolysates were generated using gastric (pepsin) and pancreatic (trypsin and chymotrypsin) enzymes for 3 and 6â¯h of hydrolysis time. Hydrolysates were characterized using degree of hydrolysis (DH) and reverse phase-high performance liquid chromatography (RP-HPLC). Camel whey protein hydrolysates (CWPHs) showed DH ranging from 11 to 47.5%, with chymotrypsin (6â¯h) and trypsin (3â¯h) generated hydrolysates exhibiting highest and lowest DH, respectively. HPLC analysis revealed that α-lactalbumin underwent complete degradation and newer shorter peptides were generated. Inhibition of cholesteryl esterase, (CE) pancreatic lipase and anti-hypertensive properties via angiotensin converting enzyme (ACE) inhibition were found to be higher in pepsin (6â¯h) and (3â¯h) generated CWPHs, respectively. Pepsin (P3 and P6) and trypsin (T6) generated hydrolysates exhibited highest anti-haemolytic activity followed by chymotrypsin generated CWPHs. Whereas, trypsin (T3) generated hydrolysate showed minimum anti-haemolytic activity (8.02%â¯Â±â¯1.40). Overall, CWPHs displayed enhanced inhibition of CE, lipase, ACE and anti-hemolytic properties upon hydrolysis, providing a strong scientific base for their potential to be considered as functional and nutraceutical ingredients. This study provides a strong indication of biologically active peptides responsible for health related bioactive properties reported herein. Future work must include identification of the peptides in the most potent camel whey protein hydrolysates.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: LWT - Volume 98, December 2018, Pages 212-218
Journal: LWT - Volume 98, December 2018, Pages 212-218
نویسندگان
Sabika Jafar, Hina Kamal, Priti Mudgil, Hassan Mohamed Hassan, Sajid Maqsood,