Hiperbilirubinemia noworodków w aspekcie polimorfizmu genu UGT1A1

Identification of UGT1A1 gene polymorphism can explain the causes of neonate hiperbilirubinemia in children with no risk factors. Moreover it would allow individual treatment options. It would also be useful in patients' development as UDP-glucuronosyltransferase is engaged in metabolism of many widely used drugs. The performed analysis justify further UGT1A1 gene polymorphism studies in Polish population and can be useful in determination of an treatment algorithm for neonates suffering from hiperbilirubinemia.