کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10222579 | 1700997 | 2018 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Intracranial and systemic manifestations of familial leptomeningeal amyloidosis, as seen on CT and MRI
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
رادیولوژی و تصویربرداری
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Intracranial and systemic manifestations of familial leptomeningeal amyloidosis, as seen on CT and MRI Intracranial and systemic manifestations of familial leptomeningeal amyloidosis, as seen on CT and MRI](/preview/png/10222579.png)
چکیده انگلیسی
Leptomeningeal amyloidosis is a subset of familial transthyretin amyloidosis, a family of diseases occurring in conjunction with multiple known mutations of the transthyretin gene. Though this is primarily a disease of the central nervous system, amyloid deposition is multisystemic. We describe a case of a 61-year-old man with known central nervous system amyloidosis presenting to the emergency room with stroke-like symptoms, including left hemineglect, right gaze paresis, and left hemiplegia, atop baseline dementia. A noncontrast CT head demonstrated ventriculomegaly and no acute hemorrhage. Urinalysis indicated an underlying urinary tract infection, ultimately believed to have prompted a breakthrough seizure. Electroencephalogram revealed diffuse encephalopathy. Contrast-enhanced MRI demonstrated hallmarks of intracranial amyloid with no new infarct. Previously taken noncontrast CT neck and thorax demonstrated evidence of systemic disease.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Radiology Case Reports - Volume 13, Issue 6, December 2018, Pages 1179-1184
Journal: Radiology Case Reports - Volume 13, Issue 6, December 2018, Pages 1179-1184
نویسندگان
Saralyn BS, Kamran MD,