کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10235187 | 45015 | 2015 | 33 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Optimizing the biological activity of Fab fragments by controlling their molecular orientation and spatial distribution across porous hydrogels
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی شیمی
بیو مهندسی (مهندسی زیستی)
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Optimizing the biological activity of Fab fragments by controlling their molecular orientation and spatial distribution across porous hydrogels Optimizing the biological activity of Fab fragments by controlling their molecular orientation and spatial distribution across porous hydrogels](/preview/png/10235187.png)
چکیده انگلیسی
- Fab fragments were gradually immobilized on aldehyde/chelate activated agarose.
- The new protocol improved the spatial distribution of immobilized Fabs.
- High Fab loads and antigen binding were achieved in the structure of the support.
- The strategy also favoured Fab functional orientation on the support.
- Immune conjugates were successfully tested with C. perfringens É-toxin.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Process Biochemistry - Volume 50, Issue 10, October 2015, Pages 1565-1571
Journal: Process Biochemistry - Volume 50, Issue 10, October 2015, Pages 1565-1571
نویسندگان
M. Ferrari, R. Barreto, E. Jackson, J.M. Guisan, F. Lopez-Gallego, L. Betancor,