کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10235463 | 45043 | 2014 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Improved microbial biosynthesis strategies and multifarious applications of the natural biopolymer epsilon-poly-l-lysine
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی شیمی
بیو مهندسی (مهندسی زیستی)
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Improved microbial biosynthesis strategies and multifarious applications of the natural biopolymer epsilon-poly-l-lysine Improved microbial biosynthesis strategies and multifarious applications of the natural biopolymer epsilon-poly-l-lysine](/preview/png/10235463.png)
چکیده انگلیسی
Epsilon-poly-l-lysine (É-PL) is a water-soluble, thermostable, biodegradable, and cationic homo-biopolymer with no toxicity to human health and the environment. It exhibits a characteristic peptide bond between the α-carboxyl groups and É-amino groups of 25-35 l-lysine residues. It has a wide antimicrobial spectrum. Microorganisms such as bacteria and fungi do not easily develop resistance to it. É-PL is polycationic in nature; therefore, it interferes with their cell membranes by ionic adsorption, leading to physiological damage to the microbial cell. É-PL producers commonly possess a membrane-bound É-PL-degrading aminopeptidase, which has high enzyme activity at pH above 4.0 and may play a role in self-protection. Because É-PL is safe for human consumption and is biodegradable, therefore it has been used in many novel applications in the fields of food, medicine, environment, agriculture, and electronics in past decades. This review article addresses the occurrence, microbial synthesis, physiochemical properties, production enhancement, biodegradation, and potential applications of É-PL.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Process Biochemistry - Volume 49, Issue 3, March 2014, Pages 496-505
Journal: Process Biochemistry - Volume 49, Issue 3, March 2014, Pages 496-505
نویسندگان
Ajay Kumar Pandey, Awanish Kumar,