Evaluation on anti-adipogenic activity of flavonoid glucopyranosides from Salicornia herbacea

► We isolated isorhamnetin and quercetin O-β-D-glucopyranosides from S. herbacea. ► The flavonoid glucopyranosides effectively suppressed adipogenic differentiation. ► Quercetin O-β-D-glucopyranoside effectively attenuated adipogenic differentiation. ► Its anti-adipogenic activity was confirmed by activation of AMPK.